Murad Night Fix Enzyme Treatment Review

Murad Night Fix Enzyme Treatment
6.6
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
3.3 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does Murad Night Fix Enzyme Treatment Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Murad Night Fix Enzyme Treatment has to offer:
 
✅ Significant moisturizing. It has a moisturizing rating of 6.6 out of 10.
✅ Modest anti-wrinkle efficacy: Murad Night Fix Enzyme Treatment has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection

  

Key Benefits of Murad Night Fix Enzyme Treatment

 
These are the key benefits you can expect from using Murad Night Fix Enzyme Treatment:
 

🔵 Lightweight Moisturizer Perfect for Combination and Oily Skin

According to CreamScan analysis, Murad Night Fix Enzyme Treatment is highly moisturizing, with a moisturizing rating of 6.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈4.0%) and Propanediol (est. ≈3.0%), and a moderate occlusivity of 3.3 out of 10, mainly due to the high content of Dimethicone (est. ≈6.0%).

This type of moisturizer is ideal for people with combination and oily skin who want maximum hydration in a relatively lightweight, non-greasy formula. It combines a significant amount of humectants with a limited amount of occlusive ingredients to boost moisturizing efficacy without feeling too heavy.

This product may also be a good choice for people with normal skin who prefer fast-absorbing textures, as it balances significant moisturizing potential with a relatively lightweight texture.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to combination and oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Murad Night Fix Enzyme Treatment has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Murad Night Fix Enzyme Treatment is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Murad Night Fix Enzyme Treatment

 
Here’s an overview of the pros and cons of Murad Night Fix Enzyme Treatment to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing perfect for combination and oily skin
✅ Also a good choice for people with normal skin who prefer fast-absorbing textures
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Murad Night Fix Enzyme Treatment

 
Based on the ingredient list analysis, CreamScan AI suggests that Murad Night Fix Enzyme Treatment
, when used alone, delivers lightweight, humectant-rich moisturizing, perfect for combination and oily skin. It's also a great option for those with normal skin who prefer fast-absorbing textures. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
Murad Night Fix Enzyme Treatment contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, Murad Night Fix Enzyme Treatment helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Dimethicone
Function:
Origin:
Glycerin
Function:
Origin:
Propanediol
Function:
Origin:
Niacinamide
Function:
Origin:
Polymethylsilsesquioxane/Silica Crosspolymer
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Isononyl Isononanoate
Function:
Origin:
Chlorella Vulgaris Extract
Function:
Origin:
Haematococcus Pluvialis Extract
Function:
Origin:
Glutamylamidoethyl Imidazole
Function:
Origin:
Cucumis Sativus (Cucumber) Fruit Extract
Function:
Origin:
Hordeum Vulgare Extract
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Extract
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Urea
Function:
Origin:
Yeast Amino Acids
Function:
Origin:
Trehalose
Function:
Origin:
Inositol
Function:
Origin:
Taurine
Function:
Origin:
Betaine
Function:
Origin:
Sorbic Acid
Function:
Origin:
Lecithin
Function:
Origin:
Mannitol
Function:
Origin:
Polysilicone-11
Function:
Origin:
Ethylhexyl Isononanoate
Function:
Origin:
PEG-7 Trimethylolpropane Coconut Ether
Function:
Origin:
Polyglyceryl-10 Dioleate
Function:
Origin:
Polyglyceryl-10 Dipalmitate
Function:
Origin:
Propylene Glycol Dicaprate
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Butylene Glycol
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Decyl Glucoside
Function:
Origin:
Polyisobutene
Function:
Origin:
Disodium EDTA
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Fragrance
Function:
Origin:
Benzyl Salicylate
Function:
Origin:
Citronellol
Function:
Origin:
Limonene
Function:
Origin:
Geraniol
Function:
Origin:
Hexyl Cinnamal
Function:
Origin:
Linalool
Function:
Origin:
Mica
Function:
Origin:
Tin Oxide
Function:
Origin:
Titanium Dioxide (CI 77891)
Function:
Origin:

Ratings

All humectants
12.3
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
6.6
6.0
0.3
0.3
Benchmark
20
Moisturizing rating
6.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.3 10
10.0
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 6.6 20
3.3
6.0
0.3
0.3
Moisturizing rating
6.6
Ingredient Est. % Benchmark Humectancy
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 12.3 10
10
All humectants
12.3
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
6
0.3
0.3
All occlusives 6.6 20
3.3
All occlusives
6.6
6.0
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
Total
3
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.5 3 Rich in antioxidants
All antioxidants
3.5
Niacinamide
2
Chlorella Vulgaris Extract
0.3
Haematococcus Pluvialis Extract
0.3
Tocopheryl Acetate
0.3
Sodium Hyaluronate
0.3
Mannitol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
All soothing 2.9 5 No
All soothing
2.9
2
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Dimethicone
Est. %6
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Propanediol
Est. %3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Polymethylsilsesquioxane/Silica Crosspolymer
Est. %1.5
Function
Origin
Polymethylsilsesquioxane/Silica Crosspolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %1.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Isononyl Isononanoate
Est. %1
Function
Origin
Isononyl IsononanoateAn ester of a branched fatty acid with a branched fatty alcohol. It is an easily spreadable emollient that has a silky, dry, non-greasy feel on the skin.
Chlorella Vulgaris Extract
Est. %0.3
Function
Origin
Chlorella Vulgaris ExtractA dried mass of tiny, single-cell green algae. It is widely used as a food source or dietary supplement since it is rich in proteins, amino acids, minerals, and vitamins. This dark green extract is used as an antioxidant agent in skincare.
Haematococcus Pluvialis Extract
Est. %0.3
Function
Origin
Haematococcus Pluvialis Extract
Glutamylamidoethyl Imidazole
Est. %0.3
Function
Origin
Glutamylamidoethyl Imidazole
Cucumis Sativus (Cucumber) Fruit Extract
Est. %0.3
Function
Origin
Cucumis Sativus (Cucumber) Fruit ExtractA soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Hordeum Vulgare Extract
Est. %0.3
Function
Origin
Hordeum Vulgare ExtractA soothing and emollient extract derived from barley, a cereal grain commonly used in the breadmaking and beer fermentation process. It contains a beneficial polysaccharide called beta-glucan, as well as flavonoids and organic acids.
Helianthus Annuus (Sunflower) Seed Extract
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) Seed ExtractAn emollient extract from sunflower seeds that is packed with beneficial-for-skin ingredients such as squalene, phytosterols, phospholipids, amino acids, and antioxidant vitamin E.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Urea
Est. %0.3
Function
Origin
UreaUrea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Yeast Amino Acids
Est. %0.3
Function
Origin
Yeast Amino AcidsYeast amino acids are both essential and non-essential amino acids derived from yeast proteins. Some of the amino acids found in yeast are histidine, lysine, and cysteine. This ingredient is a humectant that moisturizes skin by attracting water.
Trehalose
Est. %0.3
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Inositol
Est. %0.3
Function
Origin
InositolA humectant moisturizing, sugar-like compound that is present in all the cells of the body, but especially the brain. It is manufactured from sugar beets or carob tree pods for skincare purposes.
Taurine
Est. %0.3
Function
Origin
Taurine
Betaine
Est. %0.3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Sorbic Acid
Est. %0.3
Function
Origin
Sorbic AcidAn organic acid that can be naturally found in the berries of the Mountain ash, although it is manufactured synthetically for skincare purposes. It is used as a preservative and antimicrobial agent, protecting a skincare product from spoiling.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Mannitol
Est. %0.3
Function
Origin
MannitolA sweet-tasting, sugar-derived, humectant alcohol that can stabilize a skincare formula and offer some antioxidant and soothing properties.
Polysilicone-11
Est. %0.3
Function
Origin
Polysilicone-11A synthetic rubber-like substance of the silicone family that has no color or distinct scent. These are large molecules that cannot penetrate the skin but instead create a thin silky film on the skin's surface.
Ethylhexyl Isononanoate
Est. %0.3
Function
Origin
Ethylhexyl IsononanoateA synthetic ester (simple oil) that does not feel greasy or heavy. It can also reduce the sticky or greasy feeling of other ingredients.
PEG-7 Trimethylolpropane Coconut Ether
Est. %0.3
Function
Origin
PEG-7 Trimethylolpropane Coconut Ether
Polyglyceryl-10 Dioleate
Est. %0.3
Function
Origin
Polyglyceryl-10 Dioleate
Polyglyceryl-10 Dipalmitate
Est. %0.3
Function
Origin
Polyglyceryl-10 Dipalmitate
Propylene Glycol Dicaprate
Est. %0.3
Function
Origin
Propylene Glycol DicaprateA thin, non-viscous emollient that gives shine with a smooth, non-greasy, and slightly powdery after-feel. It is often compared to mineral oil and can be used to replace this heavier oil without feeling overly greasy.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Decyl Glucoside
Est. %0.3
Function
Origin
Decyl GlucosideA surfactant that can function as both a cleansing agent and emulsifier. As a cleansing agent, it is very mild on the skin. As an emulsifier, decyl glucoside will produce oil-in-water emulsions. It is naturally derived from vegetable oils and starch.
Polyisobutene
Est. %0.3
Function
Origin
PolyisobuteneA highly viscous liquid that is used in lip gloss formulations to prolong wear time and add shimmer. Polyisobutene dramatically increases the thickness of skincare products it is added to.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Benzyl Salicylate
Est. %0.3
Function
Origin
Benzyl Salicylate

A fragrance ingredient with a sweet, floral, and slightly balsamic scent. It is one of the twenty-six fragrances that are considered allergens according to the International Fragrance Association (IFRA), and so its use is restricted.

Citronellol
Est. %0.3
Function
Origin
Citronellol

A fragrant compound found naturally in many essential oils (mainly lemongrass). It can have a lemon or a rose scent. People with sensitive skin should try to avoid products with citronellol, or at least do a patch test before using it.

Limonene
Est. %0.3
Function
Origin
Limonene

One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.

Geraniol
Est. %0.3
Function
Origin
Geraniol

A fragrant, volatile, plant-based, liquid chemical that can be naturally found in many essential oils (specifically rose, palmarosa, citronella). It has a rose-like scent. It is a potential irritant and may cause an allergic reaction in some people.

Hexyl Cinnamal
Est. %0.3
Function
Origin
Hexyl Cinnamal

A synthetic scent ingredient that produces a jasmine-like fragrance. According to the International Fragrance Association (IFRA), hexyl cinnamal is a skin sensitizer and allergen and so its use in skincare should be limited.

Linalool
Est. %0.3
Function
Origin
LinaloolA fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Mica
Est. %0.3
Function
Origin
MicaA mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Tin Oxide
Est. %0.3
Function
Origin
Tin OxideA multi-functional mineral that increases the physical space a product takes up, increases the viscosity of liquid products, and, when used as an opacifying agent, makes a transparent or translucent product become opaque or solid in color.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
Titanium Dioxide (CI 77891)One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.