Radical Skincare Advanced Peptide Antioxidant Serum

Radical Skincare Advanced Peptide Antioxidant Serum
6.2
/ 10
Moisturizing
8.7 Humectancy icon Humectancy
3.8 Occlusivity icon Occlusivity
1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
$$$$

Review

Results you may expect from using Radical Skincare Advanced Peptide Antioxidant Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Radical Skincare Advanced Peptide Antioxidant Serum:

  • Significant moisturizing. It has a moisturizing rating of 6.2 out of 10.
  • Little anti-wrinkle effect: Radical Skincare Advanced Peptide Antioxidant Serum has an anti-wrinkle rating of 1.0 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Highly moisturizing: Radical Skincare Advanced Peptide Antioxidant Serum has a moisturizing rating of 6.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a very high humectancy of 8.7 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%), and a moderate occlusivity of 3.8 out of 10, mainly due to the significant content of Caprylic/Capric Triglyceride (est. ≈4.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Radical Skincare Advanced Peptide Antioxidant Serum has a minimal anti-wrinkle rating of 1.0 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:
    • Ascorbyl Tetraisopalmitate (est. ≈0.3%),
       the only derivative of Ascorbic acid with confirmed anti-wrinkle efficacy. This ingredient has below-average efficacy, proven by one study.
    • Niacinamide (est. ≈0.3%),
       one of the most effective and well-researched anti-wrinkle ingredients.
Among others, Radical Skincare Advanced Peptide Antioxidant Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Ascorbyl Glucoside, Dipalmitoyl Hydroxyproline, Camellia Sinensis Leaf Extract, Adenosine, Acetyl Hexapeptide-8, and Coffea Arabica (Coffee) Seed Extract. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Radical Skincare Advanced Peptide Antioxidant Serum is rich (> 3%) in antioxidants, specifically Ascorbyl Glucoside (est. ≈0.3%), Oryza Sativa (Rice) Bran Oil (est. ≈0.3%), Vaccinium Macrocarpon (Cranberry) Seed Oil (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
65
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
8.7
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
7.7
4.0
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
6.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 8.7 10
8.7
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 7.7 20
3.8
4.0
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
6.2
Ingredient Est. % Benchmark Humectancy
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 8.7 10
8.7
All humectants
8.7
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All occlusives 7.7 20
3.8
All occlusives
7.7
4.0
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2 /10 1 0.3 0.6
6 /10 4 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
1
Ascorbyl Tetraisopalmitate
0.6
Ingredient anti-wrinkle power
2 /10
when present at, %
1
in this formula, est. %
0.3
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Ascorbyl Glucoside
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dipalmitoyl Hydroxyproline
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Coffea Arabica (Coffee) Seed Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
1
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.9 3 Rich in antioxidants
All antioxidants
3.9
Ascorbyl Tetraisopalmitate
0.3
Niacinamide
0.3
Ascorbyl Glucoside
0.3
Oryza Sativa (Rice) Bran Oil
0.3
Vaccinium Macrocarpon (Cranberry) Seed Oil
0.3
Camellia Sinensis Leaf Extract
0.3
Euterpe Oleracea Fruit Extract
0.3
Tocopheryl Acetate
0.3
Sodium Hyaluronate
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Superoxide Dismutase
0.3
Coffea Arabica (Coffee) Seed Extract
0.3
o-Cymen-5-ol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
All soothing 1.2 5 No
All soothing
1.2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Caprylic/Capric Triglyceride
Est. %4
Function
Origin
A natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Cyclopentasiloxane
Est. %3
Function
Origin
A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Cetearyl Alcohol
Est. %2
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Cetyl Alcohol
Est. %1.5
Function
Origin
A waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Stearic Acid
Est. %1.3
Function
Origin
A saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Ceteareth-20
Est. %1
Function
Origin
A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Ascorbyl Glucoside
Est. %0.3
Function
Origin
A derivative of vitamin C. It is more stable and less irritating than ascorbic acid. There are unfortunately no clinical studies on ascorbyl glucoside’s anti-pigment or anti-acne efficacy alone.
Balanites Roxburghii Seed Oil
Est. %0.3
Function
Origin
Description is coming soon
Dipalmitoyl Hydroxyproline
Est. %0.3
Function
Origin
An amino acid derivative. It helps with skin moisturization and may have wrinkle-reducing effects.
Oryza Sativa (Rice) Bran Oil
Est. %0.3
Function
Origin
Extracted from the outer layer of rice grains, this oil is rich in occlusive moisturizing and emollient omega-6 fatty acids, vitamin E, and a potent antioxidant γ-oryzanol. It may have beneficial effects on dry or sun-damaged skin, as well as eczema.
Prunus Amygdalus Dulcis (Sweet Almond) Oil
Est. %0.3
Function
Origin
An emollient and occlusive oil derived from sweet almonds. It has a favorable fatty acid composition (mainly oleic and linoleic acids), and a high content of vitamin E. Almond oil is listed as a common comedogenic ingredient by acne.org.
Simmondsia Chinensis (Jojoba) Seed Oil
Est. %0.3
Function
Origin
A liquid plant wax, also known as Jojoba oil, pressed from the seeds of Simmondsia chinensis. These seeds can contain up to 50% of liquid wax. It is used as an occlusive moisturizer, emollient, and emulsifier.
Dimethicone
Est. %0.3
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Vaccinium Macrocarpon (Cranberry) Seed Oil
Est. %0.3
Function
Origin
Derived from cranberry seeds, this rich-in-antioxidants oil contains a combination of emollient and occlusive moisturizing omega-3,-6, and -9 fatty acids.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Argania Spinosa Leaf Extract
Est. %0.3
Function
Origin
Description is coming soon
Decarboxy Carnosine HCl
Est. %0.3
Function
Origin
Description is coming soon
Euterpe Oleracea Fruit Extract
Est. %0.3
Function
Origin
An antioxidant extract obtained from the fruits of the acai palm. It has a high content of anthocyanins, responsible for the dark purple color, as well as other antioxidant phenolic compounds.
Tocopheryl Acetate
Est. %0.3
Function
Origin
An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.
Adenosine
Est. %0.3
Function
Origin

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Sodium Hyaluronate
Est. %0.3
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
A fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
A soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Allantoin
Est. %0.3
Function
Origin
A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Ascorbyl Tetraisopalmitate
Est. %0.3
Function
Origin

Ascorbyl Tetraisopalmitate (ATIP) is an oil-soluble derivative of ascorbic acid, or vitamin C. It is more stable than ascorbic acid, with studies supporting its collagen-boosting and anti-pigment effects.

Niacinamide
Est. %0.3
Function
Origin

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Acetyl Hexapeptide-8
Est. %0.3
Function
Origin

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Superoxide Dismutase
Est. %0.3
Function
Origin
Description is coming soon
Coffea Arabica (Coffee) Seed Extract
Est. %0.3
Function
Origin
An antioxidant and emollient extract derived from coffee beans. It has been proven to improve collagen and elastin production in the skin. A small clinical study tested the anti-aging effects of coffee berry extract, and the results were very promising.
Hexapeptide-9
Est. %0.3
Function
Origin

Description is coming soon

Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Limonene
Est. %0.3
Function
Origin
One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.
Hexyl Cinnamal
Est. %0.3
Function
Origin
A synthetic scent ingredient that produces a jasmine-like fragrance. According to the International Fragrance Association (IFRA), hexyl cinnamal is a skin sensitizer and allergen and so its use in skincare should be limited.
Linalool
Est. %0.3
Function
Origin
A fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Benzyl Salicylate
Est. %0.3
Function
Origin
A fragrance ingredient with a sweet, floral, and slightly balsamic scent. It is one of the twenty-six fragrances that are considered allergens according to the International Fragrance Association (IFRA), and so its use is restricted.
Hydroxycitronellal
Est. %0.3
Function
Origin
A fragrant compound with a scent reminiscent of lilies and sweet tropical melon. It can be found in many different essential oils (such as palmarosa, ylang-ylang, and lemongrass essential oil) but is manufactured synthetically from citronellal.
Sodium Hydroxide
Est. %0.3
Function
Origin
An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
An emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Squalane
Est. %0.3
Function
Origin
An occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Cyclohexasiloxane
Est. %0.3
Function
Origin
A clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Polysorbate 60
Est. %0.3
Function
Origin
An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Sorbitan Isostearate
Est. %0.3
Function
Origin
A mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Pentylene Glycol
Est. %0.3
Function
Origin
A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.
Tromethamine
Est. %0.3
Function
Origin
An ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Chlorphenesin
Est. %0.3
Function
Origin
A preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
o-Cymen-5-ol
Est. %0.3
Function
Origin
A preservative related to chemicals found in the herb thyme. It has its own unique smell but is very effective even at small amounts.
Sodium Dehydroacetate
Est. %0.3
Function
Origin
A sodium salt of dehydroacetic acid that is most commonly used as a preservative. It is a strong fungicide and a moderate bactericide, which makes it an effective broad-spectrum preservative.