Dr. Denese SkinScience Wrinkle RX 76% Peptide Solution Concentrate

Dr. Denese SkinScience Wrinkle RX 76% Peptide Solution Concentrate
3.9
/ 10
Moisturizing
7.2 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
$$$$

Review

Results you may expect from using Dr. Denese SkinScience Wrinkle RX 76% Peptide Solution Concentrate:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Dr. Denese SkinScience Wrinkle RX 76% Peptide Solution Concentrate:

  • Light moisturizing. It has a moisturizing rating of 3.9 out of 10.

How moisturizing is it?

Lightly moisturizing: Dr. Denese SkinScience Wrinkle RX 76% Peptide Solution Concentrate has a moisturizing rating of 3.9 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a high humectancy of 7.2 out of 10, primarily due to the high content of Glycerin (est. ≈3.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Dr. Denese SkinScience Wrinkle RX 76% Peptide Solution Concentrate has a zero anti-wrinkle rating.

It contains some ingredients marketed as effective in reducing wrinkles, specifically Malus Domestica Fruit Cell Culture Extract, Tripeptide-1, Caprooyl Tetrapeptide-3, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, and Adenosine. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:
Function:
Origin:

Ratings

All humectants
7.2
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.3
1.3
Benchmark
20
Moisturizing rating
3.9
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.2 10
7.2
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.3 20
0.6
1.3
Moisturizing rating
3.9
Ingredient Est. % Benchmark Humectancy
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 7.2 10
7.2
All humectants
7.2
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.3
All occlusives 1.3 20
0.6
All occlusives
1.3
1.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Malus Domestica Fruit Cell Culture Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Caprooyl Tetrapeptide-3
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Oligopeptide
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-5
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
0.3
0.3
0.3
All antioxidants 2.4 3 No
All antioxidants
2.4
Sodium Hyaluronate
1.5
Malus Domestica Fruit Cell Culture Extract
0.3
rh-Polypeptide-79
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Cyclomethicone
Est. %6
Function
Origin
A blend of emollient silicones that leaves a smooth and non-greasy after-feel. Unlike other types of oils, it does not leave any residue on the skin, which is part of what makes it so popular.
Caprylic Acid
Est. %4
Function
Origin
Description is coming soon
Glycerin
Est. %3
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Dipropylene Glycol
Est. %2
Function
Origin
A clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Sodium Hyaluronate
Est. %1.5
Function
Origin

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Dimethicone
Est. %1.3
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
PEG/PPG-19/19 Dimethicone
Est. %1
Function
Origin
Description is coming soon
Hydrolyzed Rice Protein
Est. %0.3
Function
Origin
A protein derived from rice bran with film-forming abilities. It can help increase moisturization in skin.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Acetyl sh-Heptapeptide-1
Est. %0.3
Function
Origin
Description is coming soon
Malus Domestica Fruit Cell Culture Extract
Est. %0.3
Function
Origin
An extract that comes from a certain apple cultivar. It is claimed to have superior properties over any other apple extracts and the patent holder claims that it has anti-wrinkle activity.
rh-Polypeptide-79
Est. %0.3
Function
Origin
Description is coming soon
Tripeptide-1
Est. %0.3
Function
Origin

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Caprooyl Tetrapeptide-3
Est. %0.3
Function
Origin

A synthetically made peptide that was designed to emulate the skin growth factor. It is said to boost the production of the skin's structural elements and the dermo-epidermal junction, although this has not been independently tested.

Avena Sativa (Oat) Kernel Protein
Est. %0.3
Function
Origin
Description is coming soon
Palmitoyl Oligopeptide
Est. %0.3
Function
Origin

This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Palmitoyl Tripeptide-8
Est. %0.3
Function
Origin

Description is coming soon

Palmitoyl Tripeptide-5
Est. %0.3
Function
Origin

A small synthetic peptide that signals the skin to produce more collagen. It has been clinically tested and proven to reduce skin roughness and the appearance of wrinkles.

Oligopeptide-4
Est. %0.3
Function
Origin
Description is coming soon
Diacetyl Boldine
Est. %0.3
Function
Origin
Description is coming soon
Adenosine
Est. %0.3
Function
Origin

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Arginine
Est. %0.3
Function
Origin
A humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Dipotassium Glycyrrhizate
Est. %0.3
Function