Tripeptide-1

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.
Moisturizing
Other functions
Origin
Tripeptide-1

Overview

Tripeptide-1 is a small peptide consisting of three amino acids: glycine, histidine, and alanine. If that sounds familiar, then yes, it is the same structure as Copper Tripeptide-1 (read about it here) and Palmitoyl Tripeptide-1 (read about it here).

Its function is basically the same – it is a naturally occurring peptide found in human plasma, where it delivers copper ions. It has wound repairing properties and can regulate collagen synthesis, increase the production of elastin, proteoglycans, and glycosaminoglycans, and speed up the skin’s growth rate.

It is probably one of the most studied skincare proteins, with a solid backing in science. In its natural state, however, it can have problems crossing the skin’s barrier and absorbing into the deeper layers of the skin. This is why it is usually used conjugated with palmitic acid or biotin for better absorption.

Science

1
Gorouhi, F., & Maibach, H. I. (2009). Role of topical peptides in preventing or treating aged skin. International Journal of Cosmetic Science, 31(5), 327–345.
2
Schagen, S. (2017). Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics, 4(2), 16.