Zo Skin Health Renewal Creme Review

Zo Skin Health Renewal Creme
3.2
/ 10
Moisturizing
5.1 Humectancy icon Humectancy
1.4 Occlusivity icon Occlusivity
2.9Anti-wrinkle icon/ 10
Anti-wrinkle
Ingredients

Zo Skin Health Renewal Creme Ingredients

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Full Ingredient List (INCI):

Water, Isocetyl Stearate, Isopropyl Palmitate, Cetearyl Alcohol, Glycerin, Lactococcus Ferment Lysate, Jojoba Esters, Silica, Steareth-21, Steareth-2, Polysorbate 60, Polysorbate 20, Cocos Nucifera (Coconut) Oil, Glycine Soja (Soybean) Oil, Avena Sativa (Oat) Kernel Extract, Epilobium Angustifolium Flower/Leaf/Stem Extract, Gardenia Taitensis Flower Extract, Plankton Extract, Glycine Soja (Soybean) Sterols, Tocopherol, Retinol, Magnesium Ascorbyl Phosphate, Ectoin, Caprylyl Glycol, Polyglutamic Acid, Hexylene Glycol, Hydrogenated Lecithin, Lecithin, Ubiquinone, Acetyl Hexapeptide-8, Tetrasodium EDTA, Sodium Hyaluronate, Carbomer, Sodium Hydroxide, Citric Acid, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Sorbic Acid, Potassium Sorbate
Review

Does Zo Skin Health Renewal Creme Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Zo Skin Health Renewal Creme has to offer:
 
✅ Light moisturizing. It has a moisturizing rating of 3.2 out of 10.
✅ Modest anti-wrinkle efficacy: Zo Skin Health Renewal Creme has an anti-wrinkle rating of 2.9 out of 10 so you may expect some, although limited, effect on wrinkles.

  

Key Benefits of Zo Skin Health Renewal Creme

 
These are the key benefits you can expect from using Zo Skin Health Renewal Creme:
 

🔵 Lightweight Moisturizer Suitable for Oily Skin

According to CreamScan analysis, Zo Skin Health Renewal Creme is lightly moisturizing, with a moisturizing rating of 3.2 out of 10.

Is it more humectant or occlusive? Rather humectant. It has a low occlusivity of 1.4 out of 10 and a moderate humectancy of 5.1 out of 10, primarily due to the high content of Glycerin (est. ≈3.0%).

This product, when used alone as a moisturizer, can provide light humectant hydration in a fast-absorbing formula with a minimal amount of occlusive ingredients. This could work for people with oily skin who need a basic level of hydration.

💧  A Humectant Add-on for Any Skincare Routine

But it’s not limited to oily skin - since it contains a moderate amount of humectants, such a humectant add-on will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Zo Skin Health Renewal Creme has a modest level of anti-wrinkle efficacy, rated 2.9 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

1️⃣ Retinol (est. ≈0.1%),
 the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
 
2️⃣ Ectoin (est. ≈0.3%),
 an amino acid-derived ingredient with moderate but proven anti-wrinkle efficacy.  A single clinical study involving 104 participants (Heinrich et al.) confirmed that a cream containing 2% ectoin reduced the average wrinkle width by 7% after 4 weeks of use, compared to the same formulation without ectoin (vehicle).
 
Among others, Zo Skin Health Renewal Creme also contains some ingredients marketed often as effective in reducing wrinkles, specifically Magnesium Ascorbyl Phosphate, Ubiquinone, and Acetyl Hexapeptide-8. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Zo Skin Health Renewal Creme

 
CreamScan identified a few things to consider before adding Zo Skin Health Renewal Creme to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

📌 Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

Pros & Cons of Zo Skin Health Renewal Creme

 
Here’s an overview of the pros and cons of Zo Skin Health Renewal Creme to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides moderate humectant moisturizing suitable for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to retinol
   

Summary: Zo Skin Health Renewal Creme

 
Based on the ingredient list analysis, CreamScan AI suggests that Zo Skin Health Renewal Creme
, when used alone, provides lightweight, moderate humectant moisturizing, making it suitable for oily skin. As part of a moisturizing routine, it offers a subtle humectant enhancement, beneficial for all skin types.
 
Zo Skin Health Renewal Creme contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
That said, there are some things about Zo Skin Health Renewal Creme worth noting.
 
This product contains retinol, the most powerful and well-researched non-prescription anti-wrinkle ingredient. However, retinol can make your skin more prone to sun damage and increase sensitivity, so it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Isocetyl Stearate
Function:
Origin:
Isopropyl Palmitate
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Glycerin
Function:
Origin:
Lactococcus Ferment Lysate
Function:
Origin:
Jojoba Esters
Function:
Origin:
Silica
Function:
Origin:
Steareth-21
Function:
Origin:
Steareth-2
Function:
Origin:
Polysorbate 60
Function:
Origin:
Polysorbate 20
Function:
Origin:
Cocos Nucifera (Coconut) Oil
Function:
Origin:
Glycine Soja (Soybean) Oil
Function:
Origin:
Avena Sativa (Oat) Kernel Extract
Function:
Origin:
Epilobium Angustifolium Flower/Leaf/Stem Extract
Function:
Origin:
Gardenia Taitensis Flower Extract
Function:
Origin:
Plankton Extract
Function:
Origin:
Glycine Soja (Soybean) Sterols
Function:
Origin:
Tocopherol
Function:
Origin:
Retinol
Function:
Origin:
Magnesium Ascorbyl Phosphate
Function:
Origin:
Ectoin
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Polyglutamic Acid
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Lecithin
Function:
Origin:
Ubiquinone
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Tetrasodium EDTA
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Carbomer
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Citric Acid
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Sorbic Acid
Function:
Origin:
Potassium Sorbate
Function:
Origin:

Ratings

All humectants
5.1
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.9
2.0
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
3.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 5.1 10
5.1
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.9 20
1.4
2.0
0.3
0.3
0.3
Moisturizing rating
3.2
Ingredient Est. % Benchmark Humectancy
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 5.1 10
5.1
All humectants
5.1
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2
0.3
0.3
0.3
All occlusives 2.9 20
1.4
All occlusives
2.9
2.0
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
2.5 /10 2 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.9
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Ectoin
0.4
Ingredient anti-wrinkle power
2.5 /10
when present at, %
2
in this formula, est. %
0.3
Magnesium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.9
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 2.1 3 No
All antioxidants
2.1
Glycine Soja (Soybean) Oil
0.3
Avena Sativa (Oat) Kernel Extract
0.3
Epilobium Angustifolium Flower/Leaf/Stem Extract
0.3
Tocopherol
0.3
Magnesium Ascorbyl Phosphate
0.3
Ubiquinone
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
All soothing 2.6 5 No
All soothing
2.6
2
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Isocetyl Stearate
Est. %9
Function
Origin
Isocetyl Stearate
Isopropyl Palmitate
Est. %6
Function
Origin
Isopropyl PalmitateAn emollient ester of palmitic acid and isopropanol that gives the skin a smooth, soft, dry, non-oily after-feel. Isopropyl palmitate is listed as a common comedogenic ingredient by acne.org.
Cetearyl Alcohol
Est. %4
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Lactococcus Ferment Lysate
Est. %2.5
Function
Origin
Lactococcus Ferment LysateA relatively new probiotic ingredient. Various patents claim its moisturizing properties and in one study it was shown to improve skin barrier function.
Jojoba Esters
Est. %2
Function
Origin
Jojoba EstersA mixture of various wax esters from jojoba oil. It is used in skincare products as a fantastic emollient, soothing, and occlusive moisturizing agent that won't leave a sticky, oily feeling on the skin.
Silica
Est. %1.5
Function
Origin
SilicaA widely used cosmetic ingredient with the same chemical composition as the sand found on beaches. A common function of silica is its ability to control viscosity. In certain chemical forms, it can effectively thicken cream-style products.
Steareth-21
Est. %1.3
Function
Origin
Steareth-21One of several emulsifiers in the 'steareth' group that helps oils and water mix, especially in highly acidic emulsions. It also offers a cleansing effect to the skin.
Steareth-2
Est. %1
Function
Origin
Steareth-2A waxy, naturally derived or synthetic emulsifier that can handle extreme formula conditions such as a low pH. It offers emulsifying properties to a formula by helping oils and water to mix.
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Cocos Nucifera (Coconut) Oil
Est. %0.3
Function
Origin
Cocos Nucifera (Coconut) OilA famous occlusive moisturizing and emollient oil. It is derived from coconuts and may give a product a lovely coconut scent. Coconut oil is listed as a common comedogenic ingredient by acne.org.
Glycine Soja (Soybean) Oil
Est. %0.3
Function
Origin
Glycine Soja (Soybean) OilAn occlusive moisturizing oil expressed from soybeans. It does not leave an oily feeling on the skin due to its low content of saturated fatty acids. Glycine soja oil contains emollient fatty acids and a significant amount of antioxidants.
Avena Sativa (Oat) Kernel Extract
Est. %0.3
Function
Origin
Avena Sativa (Oat) Kernel ExtractA beneficial extract obtained from Oat groats popular in products aimed at eczema-prone skin. It contains skin healing beta-glucan, anti-inflammatory phenolic compounds, antioxidant flavonoids, various lipids, proteins, and moisturizing amino acids.
Epilobium Angustifolium Flower/Leaf/Stem Extract
Est. %0.3
Function
Origin
Epilobium Angustifolium Flower/Leaf/Stem ExtractAn extract from a plant known in North America as Fireweed and in Europe as Willowherb. It is commonly used in traditional herbal medicine. Due to its abundant content of tannins and flavonoids, it has great astringent and antioxidant properties.
Gardenia Taitensis Flower Extract
Est. %0.3
Function
Origin
Gardenia Taitensis Flower ExtractA fragrant extract from the flowers of the Tahitian gardenia that contains essential oil which has a floral, tropical scent with fresh notes.
Plankton Extract
Est. %0.3
Function
Origin
Plankton ExtractAn extract from a mixture of various tiny marine animals, algae, seaweeds, and microscopic organisms jointly called plankton. One patent refers to it as a moisturizing humectant ingredient.
Glycine Soja (Soybean) Sterols
Est. %0.3
Function
Origin
Glycine Soja (Soybean) SterolsA mixture of phytosterols isolated from soybean oil. Phytosterols, when used in skincare products, have emollient properties and can make the skin feel softer and smoother.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Magnesium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Magnesium Ascorbyl PhosphateOne of the best-researched derivatives of vitamin C. It is more resistant to light and air and retains all the properties of ascorbic acid – antioxidant, collagen-boosting, and anti-pigmentation, but with less irritation.
Ectoin
Est. %0.3
Function
Origin
Ectoin

An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.

Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Polyglutamic Acid
Est. %0.3
Function
Origin
Polyglutamic AcidA natural polymer with incredible water-binding properties that is prepared from glutamic acid through fermentation.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Ubiquinone
Est. %0.3
Function
Origin
UbiquinoneAlso known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Tetrasodium EDTA
Est. %0.3
Function
Origin
Tetrasodium EDTAOne of the most common synthetic chelators. It can reduce the 'hardness' of water and so is often used in rinse-off products.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Sorbic Acid
Est. %0.3
Function
Origin
Sorbic AcidAn organic acid that can be naturally found in the berries of the Mountain ash, although it is manufactured synthetically for skincare purposes. It is used as a preservative and antimicrobial agent, protecting a skincare product from spoiling.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.