SKINRx LAB MadeCera Cream

SKINRx LAB MadeCera Cream
6.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.9 Occlusivity icon Occlusivity
7.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Results you may expect from using SKINRx LAB MadeCera Cream:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using SKINRx LAB MadeCera Cream:

  • Significant moisturizing. It has a moisturizing rating of 6.0 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 7.5 out of 10, SKINRx LAB MadeCera Cream is effective in minimizing wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Highly moisturizing: SKINRx LAB MadeCera Cream has a moisturizing rating of 6.0 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.9 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%), Butylene Glycol (est. ≈6.0%) and Betaine (est. ≈4.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, SKINRx LAB MadeCera Cream has a high anti-wrinkle rating of 7.5 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈3.0%),
     one of the most effective and well-researched anti-wrinkle ingredients.
  • Asiaticoside (est. ≈0.3%),
     derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy confirmed by one study.
Among others, SKINRx LAB MadeCera Cream also contains some ingredients marketed as effective in reducing wrinkles, specifically Madecassic Acid, Asiatic Acid, and Adenosine. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that SKINRx LAB MadeCera Cream is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
60
Water
9
Glycerin
6
Butylene Glycol
4
Betaine
3
Niacinamide
2.5
1,2-Hexanediol
2
Hydrogenated Lecithin
1.5
Behenic Acid
1.3
Stearic Acid
1
Myristic Acid
0.3
Stearyl Alcohol
0.3
Behenyl Alcohol
0.3
Caprylic/Capric Triglyceride
0.3
Olea Europaea (Olive) Fruit Oil
0.3
Arachidyl Alcohol
0.3
Arachidyl Glucoside
0.3
Cyclopentasiloxane
0.3
Diisostearyl Malate
0.3
Ceramide NP
0.3
PEG-10 Rapeseed Sterol
0.3
Glyceryl Stearate
0.3
Glycereth-20
0.3
Dipropylene Glycol
0.3
Glycosyl Trehalose
0.3
Panthenol
0.3
PEG-100 Stearate
0.3
Dimethicone
0.3
Dimethicone/PEG-10/15 Crosspolymer
0.3
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
0.3
Lanolin
0.3
2-Hydroxyethyl Acrylate
0.3
Squalane
0.3
Polysorbate 60
0.3
Allantoin
0.3
Xanthan Gum
0.3
Asiaticoside
0.3
Madecassic Acid
0.3
Asiatic Acid
0.3
Adenosine
0.3
Dipotassium Glycyrrhizate
0.3
Madecassoside
0.3
Fragrance
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Betaine
Function:
Origin:
Niacinamide
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Behenic Acid
Function:
Origin:
Stearic Acid
Function:
Origin:
Myristic Acid
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Behenyl Alcohol
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Olea Europaea (Olive) Fruit Oil
Function:
Origin:
Arachidyl Alcohol
Function:
Origin:
Arachidyl Glucoside
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
Diisostearyl Malate
Function:
Origin:
Ceramide NP
Function:
Origin:
PEG-10 Rapeseed Sterol
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Glycereth-20
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Glycosyl Trehalose
Function:
Origin:
Panthenol
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Dimethicone
Function:
Origin:
Dimethicone/PEG-10/15 Crosspolymer
Function:
Origin:
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Function:
Origin:
Lanolin
Function:
Origin:
2-Hydroxyethyl Acrylate
Function:
Origin:
Squalane
Function:
Origin:
Polysorbate 60
Function:
Origin:
Allantoin
Function:
Origin:
Xanthan Gum
Function:
Origin:
Asiaticoside
Function:
Origin:
Madecassic Acid
Function:
Origin:
Asiatic Acid
Function:
Origin:
Adenosine
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Madecassoside
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
23.2
9
6
4
3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
3.8
1.3
1.0
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
6.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 23.2 10
10.0
9
6
4
3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 3.8 20
1.9
1.3
1.0
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
6.0
Ingredient Est. % Benchmark Humectancy
9
6
4
3
0.3
0.3
0.3
0.3
All humectants 23.2 10
10
All humectants
23.2
9
6
4
3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.3
1
0.3
0.3
0.3
0.3
0.3
All occlusives 3.8 20
1.9
All occlusives
3.8
1.3
1.0
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
3 /10 0.1 0.3 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
7.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
7.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
0.3
All antioxidants 3.9 3 Rich in antioxidants
All antioxidants
3.9
Niacinamide
3
Asiaticoside
0.3
Olea Europaea (Olive) Fruit Oil
0.3
Madecassoside
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
0.3
0.3
All soothing 4.2 5 No
All soothing
4.2
3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %6
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Betaine
Est. %4
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

1,2-Hexanediol
Est. %2.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Hydrogenated Lecithin
Est. %2
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Behenic Acid
Est. %1.5
Function
Origin
Behenic AcidA naturally-occuring ingredient from certain plant oils, behenic acid acts as an emulsifier and surfactant and provides a soft cushiony feeling.
Stearic Acid
Est. %1.3
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Myristic Acid
Est. %1
Function
Origin
Myristic AcidA common fatty acid found in various vegetable oils, most notably palm and coconut oil. It is a strongly occlusive moisturizing, emollient, and emulsifying ingredient.
Stearyl Alcohol
Est. %0.3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Behenyl Alcohol
Est. %0.3
Function
Origin
Behenyl AlcoholA fatty alcohol with emollient properties. It is used as a co-emulsifier and thickener and tends to result in a product with a smooth and creamy application texture.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Olea Europaea (Olive) Fruit Oil
Est. %0.3
Function
Origin
Olea Europaea (Olive) Fruit Oil

A famous olive oil widely used in skincare as an emollient and occlusive moisturizer. It contains mainly unsaturated fatty acids, antioxidant flavonoids, and oleuropeins. Olive oil is listed as a common comedogenic ingredient by acne.org.

Arachidyl Alcohol
Est. %0.3
Function
Origin
Arachidyl AlcoholA non-drying fatty alcohol that functions as an emollient, emulsion stabilizer, and viscosity controlling agent. It also produces a mattifying effect when applied in a skincare product onto the skin.
Arachidyl Glucoside
Est. %0.3
Function
Origin
Arachidyl GlucosideA mild cleanser and emulsifier that helps oil and water to mix and form emulsions.
Cyclopentasiloxane
Est. %0.3
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Diisostearyl Malate
Est. %0.3
Function
Origin
Diisostearyl MalateAn emollient ester that softens the skin and keeps it feeling smooth. It is characterized by a cushiony feel and glossy sheen, which is why it is frequently used in lip products.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
PEG-10 Rapeseed Sterol
Est. %0.3
Function
Origin
PEG-10 Rapeseed SterolPEG-10 Rapeseed Sterol is a mixture of polyethylene glycol (a water-soluble bulking and lubricating synthetic compound) and fat-soluble phytosterols from rapeseed oil. This mixture is used in skincare products to assist with the solubility and the of oil and water (emulsification).
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Glycereth-20
Est. %0.3
Function
Origin
Glycereth-20Description is coming soon
Dipropylene Glycol
Est. %0.3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Glycosyl Trehalose
Est. %0.3
Function
Origin
Glycosyl TrehaloseDescription is coming soon
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Dimethicone/PEG-10/15 Crosspolymer
Est. %0.3
Function
Origin
Dimethicone/PEG-10/15 CrosspolymerA self-emulsifying surfactant, which means that it can help facilitate the formation of water-in-silicone emulsions. This results in lightweight formulas with a soft finish. It can also act as a film-former and thickener.
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Est. %0.3
Function
Origin
Lauryl PEG-9 Polydimethylsiloxyethyl DimethiconeA powerful emulsifier with the unique trait of being able to work in both oil- and silicone-based formulas. It can also function as a thickener in low concentrations.
Lanolin
Est. %0.3
Function
Origin
LanolinA yellow, waxy substance obtained from sheep wool. It is one of the best emollients and emulsifiers due to its unique composition, able to relieve dry skin and repair the lipid barrier.
2-Hydroxyethyl Acrylate
Est. %0.3
Function
Origin
2-Hydroxyethyl AcrylateDescription is coming soon
Squalane
Est. %0.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Asiaticoside
Est. %0.3
Function
Origin
Asiaticoside

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Madecassic Acid
Est. %0.3
Function
Origin
Madecassic AcidAn isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
Asiatic Acid
Est. %0.3
Function
Origin
Asiatic AcidA compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Madecassoside
Est. %0.3
Function
Origin
MadecassosideAn isolated Gotu Kola compound. It helps to increase collagen and hyaluronic acid production in the skin and assists in wound healing.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.