Sesderma Salises Moisturizing Gel Review

Sesderma Salises Moisturizing Gel
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
4.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Sesderma Salises Moisturizing Gel Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Sesderma Salises Moisturizing Gel has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Considerable anti-wrinkle efficacy: Sesderma Salises Moisturizing Gel has an anti-wrinkle rating of 4.5 out of 10, indicating a moderate ability to reduce wrinkles.
  • Soothing: Sesderma Salises Moisturizing Gel contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Key Benefits of Sesderma Salises Moisturizing Gel

 
These are the key benefits you can expect from using Sesderma Salises Moisturizing Gel:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Sesderma Salises Moisturizing Gel is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Propylene Glycol (est. ≈5.0%) and Niacinamide (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Considerable Anti-Wrinkle Efficacy

According to CreamScan analysis, Sesderma Salises Moisturizing Gel has a moderate anti-wrinkle rating of 4.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈3.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Sesderma Salises Moisturizing Gel also contains contains Ammonium Glycyrrhizate and Caffeine, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Sesderma Salises Moisturizing Gel is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin Soothing and Calming Potential

Based on the ingredient list analysis, Sesderma Salises Moisturizing Gel is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈3.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Sesderma Salises Moisturizing Gel

 
CreamScan AI identified a few things to consider before adding Sesderma Salises Moisturizing Gel to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Sesderma Salises Moisturizing Gel as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Sesderma Salises Moisturizing Gel

 
Here’s an overview of the pros and cons of Sesderma Salises Moisturizing Gel to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Humectant-rich moisturizing ideal for oily skin
  • Lightweight texture
  • A humectant moisturizing boost for any skincare routine
  • Provides considerable anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage such as UV radiation and pollution
  • Contains a high concentration of soothing ingredients, which may help reduce irritation and soothe the skin

Cons: 

  • Needs occlusives to seal in humectants if used as a standalone moisturizer

Ingredients

Est. % Ingredient Origin Functions
65
7.5
5
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Alcohol Denat.
Function:
Origin:
Propylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
Triethyl Citrate
Function:
Origin:
Citric Acid
Function:
Origin:
Hydroxyethylcellulose
Function:
Origin:
Salicylic Acid
Function:
Origin:
Butylene Glycol
Function:
Origin:
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Function:
Origin:
Acetyl Dipeptide-1 Cetyl Ester
Function:
Origin:
Aesculus Hippocastanum (Horse Chestnut) Bark Extract
Function:
Origin:
Alcohol
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Alpha-Isomethyl Ionone
Function:
Origin:
Ammonium Glycyrrhizate
Function:
Origin:
Biotin
Function:
Origin:
Boswellia Serrata Gum
Function:
Origin:
Butylparaben
Function:
Origin:
Butylphenyl Methylpropional
Function:
Origin:
Caffeine
Function:
Origin:
Red 33 (CI 17200)
Function:
Origin:
Citronellol
Function:
Origin:
Limonene
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Disodium EDTA
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Ethylparaben
Function:
Origin:
Yeast Extract
Function:
Origin:
Hexyl Cinnamal
Function:
Origin:
Laureth-3
Function:
Origin:
Lecithin
Function:
Origin:
Linalool
Function:
Origin:
Methylparaben
Function:
Origin:
Panthenol
Function:
Origin:
Fragrance
Function:
Origin:
PEG-40 Hydrogenated Castor Oil
Function:
Origin:
PEG-7
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Polysorbate 20
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Propylparaben
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Trideceth-9
Function:
Origin:
Triethanolamine
Function:
Origin:
Triisopropanolamine
Function:
Origin:
Zinc Gluconate
Function:
Origin:
Zinc PCA
Function:
Origin:

Ratings

All humectants
11.4
5
3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 11.4 10
10.0
5
3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
5
3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 11.4 10
10
All humectants
11.4
5
3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
n/a
- 0.3 -
n/a
- 0.3 -
Total
4.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Ammonium Glycyrrhizate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Caffeine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
0.3
0.3
All antioxidants 4.2 3 Rich in antioxidants
All antioxidants
4.2
Niacinamide
3
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
0.3
Aloe Barbadensis Leaf Juice
0.3
Caffeine
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
1.3
0.3
0.3
0.3
0.3
All soothing 5.5 5 Rich in soothing
All soothing
5.5
3
1.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Alcohol Denat.
Est. %7.5
Function
Origin
Alcohol Denat.

Denatured alcohol is ethanol that contains additives that make it unsafe to consume. It is mainly used as a solvent and an antimicrobial agent. A major drawback to alcohol denat. is that it dries out the skin.

Propylene Glycol
Est. %5
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Triethyl Citrate
Est. %2.5
Function
Origin
Triethyl Citrate
Citric Acid
Est. %2
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Hydroxyethylcellulose
Est. %1.5
Function
Origin
HydroxyethylcelluloseA naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Salicylic Acid
Est. %1.3
Function
Origin
Salicylic AcidThis effective peeling and anti-inflammatory BHA is used as an anti-acne agent and works by breaking down the junctions between dead skin cells. This results in the peeling of dead skin and the unclogging of pores.
Butylene Glycol
Est. %1
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Est. %0.3
Function
Origin
Pentaerythrityl Tetra-di-t-butyl HydroxyhydrocinnamateAn antioxidant that protects vulnerable ingredients from the damage caused by ultraviolet radiation, which can also lead to the generation of damaging free radical species.
Acetyl Dipeptide-1 Cetyl Ester
Est. %0.3
Function
Origin
Acetyl Dipeptide-1 Cetyl EsterA dipeptide-based ingredient claimed to stimulate elastin production and reduce the appearacne of wrinkles and sagging skin.
Aesculus Hippocastanum (Horse Chestnut) Bark Extract
Est. %0.3
Function
Origin
Aesculus Hippocastanum (Horse Chestnut) Bark Extract
Alcohol
Est. %0.3
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
Aloe Barbadensis Leaf Juice
Est. %0.3
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Alpha-Isomethyl Ionone
Est. %0.3
Function
Origin
Alpha-Isomethyl IononeA fragrance ingredient that is supplied as a pale, yellow liquid. The scent it emits is very clean and features notes of violet and orris. Alpha-isomethyl is also used as a flavoring agent in lip care products and even in some foods and drinks.
Ammonium Glycyrrhizate
Est. %0.3
Function
Origin
Ammonium GlycyrrhizateA soothing ingredient with a sweet taste that is isolated from licorice root.
Biotin
Est. %0.3
Function
Origin
BiotinBiotin is an important nutrient that can cause weak hair and nails if deficient. Unfortunately, while biotin supplements have promising studies, topical biotin in creams and serums doesn’t have a large body of evidence to support its use.
Boswellia Serrata Gum
Est. %0.3
Function
Origin
Boswellia Serrata Gum
Butylparaben
Est. %0.3
Function
Origin
ButylparabenA preservative that belongs to the class of parabens. It is highly effective against the growth of fungi and yeast. There has been a lot of controversy surrounding parabens, but the concentrations in cosmetic formulations are generally considered to be safe
Butylphenyl Methylpropional
Est. %0.1
Function
Origin
Butylphenyl Methylpropional

A synthetic fragrance ingredient used to recreate the scent of lilies, this ingredient also features fresh, green, and powdery notes. Butylphenyl Methylpropional was recently labeled as Toxic to Reproduction in the EU and will be banned in 2022.

Caffeine
Est. %0.3
Function
Origin
CaffeineAn antioxidant compound that is obtained from coffee and tea leaves. It increases the microcirculation of blood in the skin and is claimed to be able to reduce the appearance of orange peel skin (although the research is lacking).
Red 33 (CI 17200)
Est. %0.3
Function
Origin
Red 33 (CI 17200)Also known as D&C Red 33 or Acid Red 33, this ingredient is a synthetic azo used to color skincare products. It produces a cool red hue, with undertones of blue that lead to a hint of purple.
Citronellol
Est. %0.3
Function
Origin
Citronellol

A fragrant compound found naturally in many essential oils (mainly lemongrass). It can have a lemon or a rose scent. People with sensitive skin should try to avoid products with citronellol, or at least do a patch test before using it.

Limonene
Est. %0.3
Function
Origin
Limonene

One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.

Dipropylene Glycol
Est. %0.3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Ethylparaben
Est. %0.3
Function
Origin
EthylparabenA cost-effective preservative that belongs to the group of parabens. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Yeast Extract
Est. %0.3
Function
Origin
Yeast ExtractAlso labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
Hexyl Cinnamal
Est. %0.3
Function
Origin
Hexyl Cinnamal

A synthetic scent ingredient that produces a jasmine-like fragrance. According to the International Fragrance Association (IFRA), hexyl cinnamal is a skin sensitizer and allergen and so its use in skincare should be limited.

Laureth-3
Est. %0.3
Function
Origin
Laureth-3
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Linalool
Est. %0.3
Function
Origin
LinaloolA fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Methylparaben
Est. %0.3
Function
Origin
MethylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
PEG-40 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
PEG-40 Hydrogenated Castor OilA castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
PEG-7
Est. %0.3
Function
Origin
PEG-7
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Propylparaben
Est. %0.3
Function
Origin
PropylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Trideceth-9
Est. %0.3
Function
Origin
Trideceth-9
Triethanolamine
Est. %0.3
Function
Origin
TriethanolamineA clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Triisopropanolamine
Est. %0.3
Function
Origin
Triisopropanolamine
Zinc Gluconate
Est. %0.3
Function
Origin
Zinc GluconateOne of the most commonly used ingredients in anti-acne products. It is an organic salt of zinc that helps to combat microbial infections, soothes and heals inflamed pimples, and regulates hormones in the skin.
Zinc PCA
Est. %0.3
Function
Origin
Zinc PCAA two-part ingredient: Zinc helps to control sebum and bacteria in acne-prone skin, while skin-identical PCA is a moisturizing humectant. Zinc PCA may even boost collagen production and so is researched as a potential anti-wrinkle ingredient.