DermaQuest DermaClear Serum

DermaQuest DermaClear Serum
4.0
/ 10
Moisturizing
6.0 Humectancy icon Humectancy
2.1 Occlusivity icon Occlusivity
1.6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
$$$$

Review

Results you may expect from using DermaQuest DermaClear Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using DermaQuest DermaClear Serum:

  • Moderate moisturizing. It has a moisturizing rating of 4.0 out of 10.
  • Little anti-wrinkle effect: DermaQuest DermaClear Serum has an anti-wrinkle rating of 1.6 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Soothing: DermaQuest DermaClear Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: DermaQuest DermaClear Serum has a moisturizing rating of 4.0 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 2.1 out of 10 and a high humectancy of 6.0 out of 10, primarily due to Glycerin (est. ≈1.5%), Butylene Glycol (est. ≈0.3%) and Sorbitol (est. ≈0.3%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, DermaQuest DermaClear Serum has a minimal anti-wrinkle rating of 1.6 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:
    • Glycolic Acid (est. ≈4.0%),
       highly effective in peelings, yet with below-average anti-wrinkle efficacy when used in leave-on skincare products.
    • Niacinamide (est. ≈0.3%),
       one of the most effective and well-researched anti-wrinkle ingredients.
Among others, DermaQuest DermaClear Serum also contains Imperata Cylindrica Root Extract, an ingredient marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Imperata Cylindrica Root Extract provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that DermaQuest DermaClear Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈0.3%), Sodium Hyaluronate (est. ≈0.3%), Tocopheryl Acetate (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, DermaQuest DermaClear Serum is rich (> 5%) in soothing ingredients, particularly Azelaic Acid (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
60
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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0.3
0.3
0.3
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0.3
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0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
6.0
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
4.2
3.0
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
4.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 6.0 10
6.0
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 4.2 20
2.1
3.0
0.3
0.3
0.3
0.3
Moisturizing rating
4.0
Ingredient Est. % Benchmark Humectancy
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 6.0 10
6
All humectants
6.0
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
3
0.3
0.3
0.3
0.3
All occlusives 4.2 20
2.1
All occlusives
4.2
3.0
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 4 1.2
6 /10 4 0.3 0.4
n/a
- 0.3 -
Total
1.6
Glycolic Acid
1.2
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
4
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Imperata Cylindrica Root Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
1.6
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3 3 Rich in antioxidants
All antioxidants
3
Niacinamide
0.3
Sodium Hyaluronate
0.3
Tocopheryl Acetate
0.3
Hexylresorcinol
0.3
Sambucus Nigra Flower Extract
0.3
Mentha Piperita (Peppermint) Leaf Extract
0.3
Veronica Officinalis Extract
0.3
Melissa Officinalis Leaf Extract
0.3
Nordihydroguaiaretic Acid
0.3
Oleanolic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 5.6 5 Rich in soothing
All soothing
5.6
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
SD Alcohol 40-B
Est. %6
Function
Origin
A natural ingredient containing a denaturant to discourage drinking.
Glycolic Acid
Est. %4
Function
Origin

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Caprylic/Capric Triglyceride
Est. %3
Function
Origin
A natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Azelaic Acid
Est. %2
Function
Origin
A powerful dermatological ingredient that helps to treat acne and various pigmentation issues. It appears both in medicated creams and regular skincare. It reduces redness and inflammation but can be irritating in high concentrations.
Glycerin
Est. %1.5
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Hexyl Laurate
Est. %1.3
Function
Origin
An emollient ester with very high spreadability.
Cetearyl Alcohol
Est. %1
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Cetearyl Olivate
Est. %0.3
Function
Origin
A multifunctional ingredient derived from plants that primarily serves as an emulsifier. Supplied as a waxy ivory-colored flake, it can also be used as an emollient and slip modifier that gives a product an overall light, silky finish.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Sorbitol
Est. %0.3
Function
Origin
A sweet-tasting alcohol derived from glucose. Aside from its sweet taste (for which it is used as a very common sweetener), Sorbitol is also very good at retaining water and is used in skincare as a humectant.
Lactic Acid
Est. %0.3
Function
Origin
The most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Sorbitan Olivate
Est. %0.3
Function
Origin
An ester of sorbitol (a type of sugar alcohol) and olive oil fatty acids. It is used as an emulsifying agent to stabilize oil droplets in water (or vice versa).
PPG-12/SMDI Copolymer
Est. %0.3
Function
Origin
Description is coming soon
Niacinamide
Est. %0.3
Function
Origin

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Cetyl Alcohol
Est. %0.3
Function
Origin
A waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Sodium Hyaluronate
Est. %0.3
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Dicetyl Phosphate
Est. %0.3
Function
Origin
Description is coming soon
Ceteth-10 Phosphate
Est. %0.3
Function
Origin
Description is coming soon
Stearic Acid
Est. %0.3
Function
Origin
A saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Glyceryl Stearate
Est. %0.3
Function
Origin
An emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %0.3
Function
Origin
This surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Tocopheryl Acetate
Est. %0.3
Function
Origin
An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.
Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
A semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Mangifera Indica (Mango) Seed Butter
Est. %0.3
Function
Origin
A fat obtained from the kernel of the mango seed. It is a semi-solid, plant-based butter that is used for consumption, and as an emollient and occlusive moisturizer in skincare.
Dimethicone
Est. %0.3
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Ethyl Linoleate
Est. %0.3
Function
Origin
Description is coming soon
Hexylresorcinol
Est. %0.3
Function
Origin
A synthetic compound. It is an anti-pigment ingredient that has been shown to be effective in inhibiting tyrosinase activity.
Yeast Polysaccharides
Est. %0.3
Function
Origin
Description is coming soon
Propylene Glycol
Est. %0.3
Function
Origin
A clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Symphytum Officinale Rhizome/Root Extract
Est. %0.3
Function
Origin
Description is coming soon
Plantago Ovata Seed Extract
Est. %0.3
Function
Origin
Description is coming soon
Glutamine
Est. %0.3
Function
Origin
A humectant moisturizing amino acid that, aside from attracting water to the skin’s surface, can also soothe allergic itching and reduce the signs of inflammation.
Proline
Est. %0.3
Function
Origin
The best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Leucine
Est. %0.3
Function
Origin
A humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to increase water content on the skin’s surface and is often used in conjunction with anti-pigmentation products.
Serine
Est. %0.3
Function
Origin
A non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Hedera Helix (Ivy) Leaf/Stem Extract
Est. %0.3
Function
Origin
Description is coming soon
Cucumis Sativus (Cucumber) Fruit Extract
Est. %0.3
Function
Origin
A soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Sambucus Nigra Flower Extract
Est. %0.3
Function
Origin
Derived from the plant called black elder or elderberry, this extract is an occlusive and soothing ingredient that also contains antioxidant flavonoids.
Arnica Montana Flower Extract
Est. %0.3
Function
Origin
An extract derived from the flower heads of the mountain arnica plant. This plant is used as herbal medicine to treat wounds, bruises, and inflammation. In skincare, however, it is mostly added for fragrance purposes due to its pleasant pine and sage odor.
Parietaria Officinalis Extract
Est. %0.3
Function
Origin
Description is coming soon
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Ethylhexylglycerin
Est. %0.3
Function
Origin
A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Hexylene Glycol
Est. %0.3
Function
Origin
A multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Lavandula Angustifolia (Lavender) Oil
Est. %0.3
Function
Origin
An essential oil derived from common, or true, lavender. It is used in skincare for its lovely, calming scent. Like all essential oils, however, it may cause a contact skin allergy in more sensitive individuals.
Imperata Cylindrica Root Extract
Est. %0.3
Function
Origin
An extract obtained from cogongrass roots. According to the patent holder, it contains significant amounts of potassium, a humectant and anti-wrinkle compound, as well as sulfur-containing proteins.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
A synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Malva Sylvestris (Mallow) Extract
Est. %0.3
Function
Origin
A vibrant, purple extract obtained from the dark flowers of common mallow. Its main active ingredient is an emollient and soothing thick mucilage.
Mentha Piperita (Peppermint) Leaf Extract
Est. %0.3
Function
Origin
A fragrant extract derived from the leaves of peppermint. It contains a pleasant-smelling essential oil, as well as plenty of antioxidant flavonoids, terpenes, and phenolic acids.
Primula Veris Extract
Est. %0.3
Function
Origin
Derived from either the root or flower of the cowslip primrose, this soothing extract contains anti-inflammatory triterpene saponins and phenolic acids.
Alchemilla Vulgaris Extract
Est. %0.3
Function
Origin
A soothing extract that is derived from the lady's mantle plant. It contains plenty of astringent tannins and certain anti-inflammatory compounds.
Veronica Officinalis Extract
Est. %0.3
Function
Origin
An antioxidant extract obtained from a native European flowering plant called heath speedwell, otherwise known as Paul's betony.
Melissa Officinalis Leaf Extract
Est. %0.3
Function
Origin
A fragrant extract derived from lemon balm leaves with antioxidant and antiviral flavonoids and terpenes. It has a lovely, fresh, lemon-like scent.
Achillea Millefolium Extract
Est. %0.3
Function
Origin
An extract obtained from the common yarrow. It is full of astringent and anti-inflammatory phytochemicals that help with inflamed skin and wound healing, have soothing and refreshing effects on the skin, and give the product a fresh, green, and spicy scent.
Hydrolyzed Vegetable Protein
Est. %0.3
Function
Origin
A blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Glycosaminoglycans
Est. %0.3
Function
Origin
A blanket term used for the structural polysaccharides of the skin, such as hyaluronic acid and chondroitin. They add to a skincare product's film-forming and water-binding properties.
Salix Alba (Willow) Bark Extract
Est. %0.3
Function
Origin
A potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Arctostaphylos Uva-Ursi Leaf Extract
Est. %0.3
Function
Origin
Description is coming soon
Mitracarpus Scaber Extract
Est. %0.3
Function
Origin
Description is coming soon
PEG-60 Almond Glycerides
Est. %0.3
Function
Origin
Description is coming soon
Nordihydroguaiaretic Acid
Est. %0.3
Function
Origin
A powerful antioxidant and anti-inflammatory phytochemical obtained from Creosote bush. It can also be created synthetically.
Oleanolic Acid
Est. %0.3
Function
Origin

A plant-based terpenoid with antioxidant and anti-inflammatory properties.

Glycine
Est. %0.3
Function
Origin
A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Hydrolyzed Wheat Protein
Est. %0.3
Function
Origin
Wheat protein broken down into its individual amino acids. It is commonly used as a film-former and antistatic agent.
Hydrolyzed Wheat Starch
Est. %0.3
Function
Origin
Description is coming soon
Maltodextrin
Est. %0.3
Function
Origin
A formula helper manufactured from starch. It has a sweet flavor and is often used in rinse-off products to support their foaming structure. Maltodextrin is also used to stabilize emulsions and to absorb and bind other ingredients in the formula.
Syringa Vulgaris (Lilac) Leaf Cell Culture Extract
Est. %0.3
Function
Origin
Description is coming soon
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Magnesium Aluminum Silicate
Est. %0.3
Function
Origin
A naturally occurring clay that is hygroscopic, which means that it easily absorbs water. This ingredient is thus commonly used as an absorbent and emulsion stabilizer. It also modifies slip by improving the spreadability of the products it is used in.
Ammonium Hydroxide
Est. %0.3
Function
Origin
A weakly basic ingredient that can adjust pH to a higher level.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.