ROSE Ingleton MD Signature Moisturizer

ROSE Ingleton MD Signature Moisturizer
9.5
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
9.0 Occlusivity icon Occlusivity
3.9Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does ROSE Ingleton MD Signature Moisturizer work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using ROSE Ingleton MD Signature Moisturizer:

  • Intense moisturizing. It has a moisturizing rating of 9.5 out of 10.
  • Some anti-wrinkle efficacy: ROSE Ingleton MD Signature Moisturizer has an anti-wrinkle rating of 3.9 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Perfect moisturizer for dry skin

According to CreamScan analysis, ROSE Ingleton MD Signature Moisturizer is intensely moisturizing, with a moisturizing rating of 9.5 out of 10.

Is it more humectant or occlusive? Rather humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈4.0%) and Niacinamide (est. ≈2.5%), and a very high occlusivity of 9.0 out of 10, mainly due to the significant content of Dimethicone (est. ≈9.0%) and Caprylic/Capric Triglyceride (est. ≈6.0%).

This type of moisturizer is ideal for people with dry skin who want intense hydration. It combines a high concentration of humectants and occlusive ingredients to provide effective dual-action moisturizing specifically for dry skin.

The occlusive profile of ROSE Ingleton MD Signature Moisturizer suggests a rich, thick texture, making it perfectly suited for dry skin.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, ROSE Ingleton MD Signature Moisturizer has a slight anti-wrinkle rating of 3.9 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈2.5%),
     one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
  • Glycolic Acid (est. ≈0.3%),
     a highly effective ingredient in peelings but with moderate anti-wrinkle efficacy in leave-on skincare products, as supported by a single clinical study. This study, involving 72 participants (Thibault et al.), demonstrated that a lotion with 5% GA reduced the fine wrinkling score by 6% after 34 days of use, compared to a vehicle (the same formulation without GA).
Among others, ROSE Ingleton MD Signature Moisturizer also contains some ingredients marketed often as effective in reducing wrinkles, specifically Ascorbyl Glucoside, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that ROSE Ingleton MD Signature Moisturizer is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.5%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Dimethicone
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Glycerin
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Niacinamide
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Castanea Sativa (Chestnut) Seed Extract
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Sorbitan Stearate
Function:
Origin:
Ascorbyl Glucoside
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Ceramide NP
Function:
Origin:
Ceramide AP
Function:
Origin:
Ceramide EOP
Function:
Origin:
Trehalose
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Cucumis Sativus (Cucumber) Fruit Extract
Function:
Origin:
Vaccinium Myrtillus Fruit Extract
Function:
Origin:
Saccharum Officinarum (Sugarcane) Extract
Function:
Origin:
Acer Saccharum (Sugar Maple) Extract
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Fruit Extract
Function:
Origin:
Citrus Limon (Lemon) Fruit Extract
Function:
Origin:
Lactic Acid
Function:
Origin:
Glycolic Acid
Function:
Origin:
Citric Acid
Function:
Origin:
Malic Acid
Function:
Origin:
Tartaric Acid
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Sodium PCA
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Phytosphingosine
Function:
Origin:
Cholesterol
Function:
Origin:
Sodium Lauroyl Lactylate
Function:
Origin:
Sodium Citrate
Function:
Origin:
Carbomer
Function:
Origin:
Xanthan Gum
Function:
Origin:
Polysorbate 20
Function:
Origin:
Mica
Function:
Origin:
Titanium Dioxide (CI 77891)
Function:
Origin:
Iron Oxides (CI 77491)
Function:
Origin:
Tetrasodium Glutamate Diacetate
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:

Ratings

All humectants
10.6
4
2.5
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
18.0
9.0
6.0
3.0
Benchmark
20
Moisturizing rating
9.5
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.6 10
10.0
4
2.5
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 18.0 20
9.0
9.0
6.0
3.0
Moisturizing rating
9.5
Ingredient Est. % Benchmark Humectancy
4
2.5
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 10.6 10
10
All humectants
10.6
4
2.5
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
9
6
3
All occlusives 18.0 20
9.0
All occlusives
18.0
9.0
6.0
3.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2.5 3.8
1.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3.9
Niacinamide
3.8
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2.5
Glycolic Acid
0.1
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
0.3
Ascorbyl Glucoside
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3.9
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.1 3 Rich in antioxidants
All antioxidants
6.1
Niacinamide
2.5
Castanea Sativa (Chestnut) Seed Extract
1.5
Ascorbyl Glucoside
0.3
Sodium Hyaluronate
0.3
Vaccinium Myrtillus Fruit Extract
0.3
Saccharum Officinarum (Sugarcane) Extract
0.3
Acer Saccharum (Sugar Maple) Extract
0.3
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2.5
0.3
0.3
All soothing 3.1 5 No
All soothing
3.1
2.5
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Dimethicone
Est. %9
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Caprylic/Capric Triglyceride
Est. %6
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butyrospermum Parkii (Shea) Butter
Est. %3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Niacinamide
Est. %2.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Pentylene Glycol
Est. %2
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Castanea Sativa (Chestnut) Seed Extract
Est. %1.5
Function
Origin
Castanea Sativa (Chestnut) Seed ExtractAn antioxidant extract obtained from edible chestnut seeds that has astringent tannins and some humectant moisturizing oligosaccharides. More research is needed to explore its effects on the skin.
Cetearyl Alcohol
Est. %1.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %1
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Sorbitan Stearate
Est. %0.3
Function
Origin
Sorbitan StearateA vegetable-derived ingredient most commonly used as an emulsifier to stabilize water and oil mixtures.
Ascorbyl Glucoside
Est. %0.3
Function
Origin
Ascorbyl GlucosideA derivative of vitamin C. It is more stable and less irritating than ascorbic acid. There are unfortunately no clinical studies on ascorbyl glucoside’s anti-pigment or anti-acne efficacy alone.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Ceramide AP
Est. %0.3
Function
Origin
Ceramide APPreviously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Ceramide EOP
Est. %0.3
Function
Origin
Ceramide EOP

Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.

Trehalose
Est. %0.3
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Cucumis Sativus (Cucumber) Fruit Extract
Est. %0.3
Function
Origin
Cucumis Sativus (Cucumber) Fruit ExtractA soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Vaccinium Myrtillus Fruit Extract
Est. %0.3
Function
Origin
Vaccinium Myrtillus Fruit ExtractAn extract derived from the berries of the bilberry plant, sometimes called European blueberry. It is rich in antioxidant anthocyanins and astringent tannins.
Saccharum Officinarum (Sugarcane) Extract
Est. %0.3
Function
Origin
Saccharum Officinarum (Sugarcane) ExtractAn antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Acer Saccharum (Sugar Maple) Extract
Est. %0.3
Function
Origin
Acer Saccharum (Sugar Maple) ExtractAn antioxidant extract from sugar maple bark and sap – the same sweet sap used to make maple syrup. It has a faint vanilla smell and is used in skincare for its exfoliating properties. This is because of the small sugar crystals present in the extract.
Citrus Aurantium Dulcis (Orange) Fruit Extract
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Fruit Extract

An extract from the fruit of the sweet orange. It contains fragrant sweet orange essential oil, high amounts of antioxidant flavonoids (mainly hesperidin), and carotenoids – which give it the orange color.

Citrus Limon (Lemon) Fruit Extract
Est. %0.3
Function
Origin
Citrus Limon (Lemon) Fruit Extract

A fragrant extract from lemon peels that contains various antioxidant flavonoids, organic acids, and limonoids – which are currently under investigation as potential anti-wrinkle and anti-pigment compounds.

Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Glycolic Acid
Est. %0.3
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Malic Acid
Est. %0.3
Function
Origin
Malic AcidA simple organic alpha-hydroxy acid (AHA) commonly found in unripe fruits. It is more gentle of an exfoliant when compared to the famous and potent glycolic and lactic acids.
Tartaric Acid
Est. %0.3
Function
Origin
Tartaric AcidA less used AHA. It is mostly used as a pH adjusting ingredient and its effects on the skin are yet to be researched. Its derivatives are used in a similar manner to barrier-repairing ceramides.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Sodium PCA
Est. %0.3
Function
Origin
Sodium PCAOne of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Phytosphingosine
Est. %0.3
Function
Origin
PhytosphingosineA key component of ceramides NP, AP, and EOP. It has barrier repair properties and stimulates the production of the skin’s Natural Moisturizing Factor. Phytosphingosine has strong antimicrobial and anti-inflammatory activity, which can be used to treat acne.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Sodium Lauroyl Lactylate
Est. %0.3
Function
Origin
Sodium Lauroyl LactylateA multifunctional ingredient that produces foamy cleansers and allows oil and water to mix.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Mica
Est. %0.3
Function
Origin
MicaA mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
Titanium Dioxide (CI 77891)One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Iron Oxides (CI 77491)
Est. %0.3
Function
Origin
Iron Oxides (CI 77491)A red colorant also known as red iron oxide. This is an EU-approved colorant used in a wide variety of products.
Tetrasodium Glutamate Diacetate
Est. %0.3
Function
Origin
Tetrasodium Glutamate DiacetateA biodegradable chelating agent that chemically captures the heavy metal ions naturally present in water and disarms their harmful effects.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.