NeoStrata Dermal Replenishment Face Cream

NeoStrata Dermal Replenishment Face Cream
5.4
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.8 Occlusivity icon Occlusivity

Review

Does NeoStrata Dermal Replenishment Face Cream work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using NeoStrata Dermal Replenishment Face Cream:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.4 out of 10.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, NeoStrata Dermal Replenishment Face Cream is quite moisturizing, with a moisturizing rating of 5.4 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.8 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Questionable anti-wrinkle efficacy

According to CreamScan analysis, NeoStrata Dermal Replenishment Face Cream has a zero anti-wrinkle rating.

It contains some ingredients often marketed as effective in reducing wrinkles, specifically Acetyl Glucosamine, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
55
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Maltobionic Acid
Function:
Origin:
Acetyl Glucosamine
Function:
Origin:
Octyldodecyl Neopentanoate
Function:
Origin:
Steareth-2
Function:
Origin:
C12-15 Alkyl Benzoate
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Octyldodecanol
Function:
Origin:
Steareth-20
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Isostearic Acid
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
Acetyl Tyrosinamide
Function:
Origin:
Saccharide Isomerate
Function:
Origin:
Cyclohexasiloxane
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Vitis Vinifera (Grape) Seed Extract
Function:
Origin:
Sodium PCA
Function:
Origin:
Serine
Function:
Origin:
Glycine
Function:
Origin:
Alanine
Function:
Origin:
Lysine
Function:
Origin:
Arginine
Function:
Origin:
Threonine
Function:
Origin:
Proline
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Propylene Glycol
Function:
Origin:
Betaine
Function:
Origin:
Sorbitol
Function:
Origin:
Isopropyl Myristate
Function:
Origin:
Glutamic Acid
Function:
Origin:
Butylene Glycol
Function:
Origin:
Polysorbate 60
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Carbomer
Function:
Origin:
Polysorbate 20
Function:
Origin:
Ammonium Hydroxide
Function:
Origin:
Disodium EDTA
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Sodium Bisulfite
Function:
Origin:
Xanthan Gum
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Chlorphenesin
Function:
Origin:
Methyldihydrojasmonate
Function:
Origin:
Isobutyl Methyl Tetrahydropyranol
Function:
Origin:
Ethylene Brassylate
Function:
Origin:
Methyl Decenol
Function:
Origin:
Red 4 (CI 14700)
Function:
Origin:
Yellow 5 (CI 19140)
Function:
Origin:

Ratings

All humectants
13.2
9
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.5
1.5
Benchmark
20
Moisturizing rating
5.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 13.2 10
10.0
9
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.5 20
0.8
1.5
Moisturizing rating
5.4
Ingredient Est. % Benchmark Humectancy
9
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 13.2 10
10
All humectants
13.2
9
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.5
All occlusives 1.5 20
0.8
All occlusives
1.5
1.5
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 4 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Acetyl Glucosamine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
4
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
All antioxidants 0.6 3 No
All antioxidants
0.6
Vitis Vinifera (Grape) Seed Extract
0.3
Sodium Bisulfite
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %55
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Maltobionic Acid
Est. %6
Function
Origin
Maltobionic Acid
Acetyl Glucosamine
Est. %4
Function
Origin
Acetyl GlucosamineA body-natural amino-saccharide used in skincare as an anti-pigment ingredient. Some other benefits of acetyl glucosamine include decreased skin flakiness, improved wound healing, and even a slight reduction in facial wrinkles.
Octyldodecyl Neopentanoate
Est. %3
Function
Origin
Octyldodecyl NeopentanoateA synthetic emollient ester. This clear, colorless liquid has a unique sensorial profile that is light and silky, with good lubricity.
Steareth-2
Est. %2.5
Function
Origin
Steareth-2A waxy, naturally derived or synthetic emulsifier that can handle extreme formula conditions such as a low pH. It offers emulsifying properties to a formula by helping oils and water to mix.
C12-15 Alkyl Benzoate
Est. %2
Function
Origin
C12-15 Alkyl BenzoateA synthetic emollient ester. It works to improve the appearance of the skin by filling in the microcracks on the surface, thereby making the skin appear softer and smoother. It imparts a lightweight, velvety feel.
Butyrospermum Parkii (Shea) Butter
Est. %1.5
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Octyldodecanol
Est. %1.3
Function
Origin
OctyldodecanolAn emollient fatty alcohol that spreads easily without leaving a greasy residue on the skin. It is also used as a solvent and dispersing agent for other ingredients.
Steareth-20
Est. %1
Function
Origin
Steareth-20A white to light brown reaction product of a clear gas and stearyl alcohol. Like the other steareth ingredients, steareth-20 is a waxy emulsifier that can help to form a stable emulsion, even in extreme conditions.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Isostearic Acid
Est. %0.3
Function
Origin
Isostearic AcidA saturated fatty acid used to mix oil and water and to remove dirt from the skin's surface. Isostearic acid is listed among common comedogenic ingredients by acne.org.
Cyclopentasiloxane
Est. %0.3
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Acetyl Tyrosinamide
Est. %0.3
Function
Origin
Acetyl Tyrosinamide
Saccharide Isomerate
Est. %0.3
Function
Origin
Saccharide IsomerateA naturally-derived humectant that provides moisturization at low levels and is less sticky than other humectants like glycerin.
Cyclohexasiloxane
Est. %0.3
Function
Origin
CyclohexasiloxaneA clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Vitis Vinifera (Grape) Seed Extract
Est. %0.3
Function
Origin
Vitis Vinifera (Grape) Seed ExtractA potent antioxidant and emollient extract derived from grape seeds. It contains antioxidant flavonoids, tannins, proanthocyanidins, phytosterols, carotenoids, and vitamin E. It is often used in skincare products aimed at soothing and healing irritated skin.
Sodium PCA
Est. %0.3
Function
Origin
Sodium PCAOne of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Lysine
Est. %0.3
Function
Origin
LysineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It is slightly alkaline and helps to balance the product's pH. It may have a slightly fishy smell.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Threonine
Est. %0.3
Function
Origin
ThreonineAn essential amino acid that may play a role in collagen production. However, more research is needed in order to confirm or deny these claims.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Propylene Glycol
Est. %0.3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Betaine
Est. %0.3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Sorbitol
Est. %0.3
Function
Origin
SorbitolA sweet-tasting alcohol derived from glucose. Aside from its sweet taste (for which it is used as a very common sweetener), Sorbitol is also very good at retaining water and is used in skincare as a humectant.
Isopropyl Myristate
Est. %0.3
Function
Origin
Isopropyl MyristateA fast-spreading, cost-effective, non-greasy emollient that is typically used for lubrication, spreadability, or to remove “tackiness” from a product. Isopropyl Myristate is listed as a common comedogenic ingredient by acne.org.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Ammonium Hydroxide
Est. %0.3
Function
Origin
Ammonium HydroxideA weakly basic ingredient that can adjust pH to a higher level.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Sodium Bisulfite
Est. %0.3
Function
Origin
Sodium BisulfiteAn inorganic salt that kills bacteria and protects against oxidation.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Methyldihydrojasmonate
Est. %0.3
Function
Origin
Methyldihydrojasmonate
Isobutyl Methyl Tetrahydropyranol
Est. %0.3
Function
Origin
Isobutyl Methyl Tetrahydropyranol
Ethylene Brassylate
Est. %0.3
Function
Origin
Ethylene BrassylateA synthetic fragrance ingredient known for its musky scent. Like most fragrance ingredients, it can be irritating.
Methyl Decenol
Est. %0.3
Function
Origin
Methyl Decenol
Red 4 (CI 14700)
Est. %0.3
Function
Origin
Red 4 (CI 14700)A synthetic dye that is also known as FD&C Red No. 4. This colorant produces a warm red hue that has an orange or yellow undertone.
Yellow 5 (CI 19140)
Est. %0.3
Function
Origin
Yellow 5 (CI 19140)A bright yellow colorant that is often also listed as FD&C Yellow 5.