NeoStrata Cellular Restoration Review

NeoStrata Cellular Restoration
4.2
/ 10
Moisturizing
7.0 Humectancy icon Humectancy
1.4 Occlusivity icon Occlusivity
1.5Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does NeoStrata Cellular Restoration Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what NeoStrata Cellular Restoration has to offer:
 
Moderate moisturizing. It has a moisturizing rating of 4.2 out of 10.
✅ Slight anti-wrinkle effect: NeoStrata Cellular Restoration has an anti-wrinkle rating of 1.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

  

Key Benefits of NeoStrata Cellular Restoration

 
These are the key benefits you can expect from using NeoStrata Cellular Restoration:
 

🔵 Lightweight Moisturizer Well-Suited for Oily Skin

According to CreamScan analysis, NeoStrata Cellular Restoration is quite moisturizing, with a moisturizing rating of 4.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.4 out of 10 and a high humectancy of 7.0 out of 10, primarily due to the high content of Gluconolactone (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It can also be a good option for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Enhancement for Any Skincare Routine

But it’s not limited to oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, NeoStrata Cellular Restoration has a slight anti-wrinkle rating of 1.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈6.0%),
 a highly effective ingredient in peelings but with moderate anti-wrinkle efficacy in leave-on skincare products, as supported by a single clinical study. This study, involving 72 participants (Thibault et al.), demonstrated that a lotion with 5% GA reduced the fine wrinkling score by 6% after 34 days of use, compared to a vehicle (the same formulation without GA).
 
Among others, NeoStrata Cellular Restoration contains some ingredients often marketed as effective in reducing wrinkles, specifically Gluconolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, and Malus Domestica Fruit Cell Culture Extract. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: NeoStrata Cellular Restoration

 
CreamScan AI identified a few things to consider before adding NeoStrata Cellular Restoration to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Glycolic Acid

This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. Its action works by removing dead skin cells, revealing new, more delicate skin that is particularly vulnerable to sun damage.

As a result, using products with glycolic acid, regardless of concentration, may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To counteract this increased sun sensitivity, apply a broad-spectrum sunscreen with at least SPF 30 daily to protect your skin during glycolic acid treatment.

❗️Please always check the manufacturer's instructions for using the product, either on their website or product label.

Pros & Cons of NeoStrata Cellular Restoration

 
Here’s an overview of the pros and cons of NeoStrata Cellular Restoration to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing well-suited for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
Provides slight anti-wrinkle efficacy
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to glycolic acid
   

Summary: NeoStrata Cellular Restoration

 
Based on the ingredient list analysis, CreamScan AI suggests that NeoStrata Cellular Restoration
, when used alone, delivers lightweight, humectant-rich moisturizing that is well-suited for oily skin. As part of a moisturizing routine, it provides a humectant enhancement, beneficial for all skin types.
 
NeoStrata Cellular Restoration contains ingredients with proven evidence of anti-wrinkle efficacy that may offer a slight anti-wrinkle effect. As a result, you can expect a positive, though relatively minimal, impact on wrinkles.
 
 
That said, there are some things about NeoStrata Cellular Restoration worth noting.
 
This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. However, glycolic acid - regardless of concentration - can increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays. Therefore, it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 during glycolic acid treatment.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Glycolic Acid
Function:
Origin:
Maltobionic Acid
Function:
Origin:
Gluconolactone
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Isononyl Isononanoate
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Hydrogenated Polydecene
Function:
Origin:
Arginine
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Dimethicone
Function:
Origin:
Ammonium Hydroxide
Function:
Origin:
Propylene Glycol
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Cyclohexasiloxane
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Malus Domestica Fruit Cell Culture Extract
Function:
Origin:
Vitis Vinifera (Grape) Seed Extract
Function:
Origin:
Euterpe Oleracea Fruit Extract
Function:
Origin:
Punica Granatum Extract
Function:
Origin:
Vaccinium Angustifolium (Blueberry) Fruit Juice
Function:
Origin:
Rosa Damascena Flower Oil
Function:
Origin:
Methyldihydrojasmonate
Function:
Origin:
Ethylene Brassylate
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Lecithin
Function:
Origin:
PEG-75 Stearate
Function:
Origin:
Steareth-20
Function:
Origin:
Ceteth-20
Function:
Origin:
Triethyl Citrate
Function:
Origin:
Xanthan Gum
Function:
Origin:
Magnesium Aluminum Silicate
Function:
Origin:
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Function:
Origin:
Sodium Bisulfite
Function:
Origin:
Disodium EDTA
Function:
Origin:
Carbomer
Function:
Origin:
Polysorbate 20
Function:
Origin:
Chlorphenesin
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Caramel
Function:
Origin:
Yellow 5 (CI 19140)
Function:
Origin:

Ratings

All humectants
7.0
3
1.5
1.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.8
2.5
0.3
Benchmark
20
Moisturizing rating
4.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.0 10
7.0
3
1.5
1.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.8 20
1.4
2.5
0.3
Moisturizing rating
4.2
Ingredient Est. % Benchmark Humectancy
3
1.5
1.3
0.3
0.3
0.3
0.3
All humectants 7.0 10
7
All humectants
7.0
3
1.5
1.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2.5
0.3
All occlusives 2.8 20
1.4
All occlusives
2.8
2.5
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 6 1.5
n/a
- 3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
1.5
Glycolic Acid
1.5
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
6
Gluconolactone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Malus Domestica Fruit Cell Culture Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
1.5
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 2.4 3 No
All antioxidants
2.4
Tocopheryl Acetate
0.3
Malus Domestica Fruit Cell Culture Extract
0.3
Vitis Vinifera (Grape) Seed Extract
0.3
Euterpe Oleracea Fruit Extract
0.3
Punica Granatum Extract
0.3
Rosa Damascena Flower Oil
0.3
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
0.3
Sodium Bisulfite
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glyceryl Stearate
Est. %9
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Glycolic Acid
Est. %6
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Maltobionic Acid
Est. %4
Function
Origin
Maltobionic Acid
Gluconolactone
Est. %3
Function
Origin
GluconolactoneA PHA derived from glucose. It has exfoliating and humectant properties and acts as a penetration enhancer for other ingredients. It has also been shown to assist in the treatment of acne and the prevention of photoaging.
Butyrospermum Parkii (Shea) Butter
Est. %2.5
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Isononyl Isononanoate
Est. %2
Function
Origin
Isononyl IsononanoateAn ester of a branched fatty acid with a branched fatty alcohol. It is an easily spreadable emollient that has a silky, dry, non-greasy feel on the skin.
Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %1.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Stearyl Alcohol
Est. %1
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Hydrogenated Polydecene
Est. %0.3
Function
Origin
Hydrogenated PolydeceneA clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Cyclopentasiloxane
Est. %0.3
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Ammonium Hydroxide
Est. %0.3
Function
Origin
Ammonium HydroxideA weakly basic ingredient that can adjust pH to a higher level.
Propylene Glycol
Est. %0.3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Cyclohexasiloxane
Est. %0.3
Function
Origin
CyclohexasiloxaneA clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Malus Domestica Fruit Cell Culture Extract
Est. %0.3
Function
Origin
Malus Domestica Fruit Cell Culture ExtractAn extract that comes from a certain apple cultivar. It is claimed to have superior properties over any other apple extracts and the patent holder claims that it has anti-wrinkle activity.
Vitis Vinifera (Grape) Seed Extract
Est. %0.3
Function
Origin
Vitis Vinifera (Grape) Seed ExtractA potent antioxidant and emollient extract derived from grape seeds. It contains antioxidant flavonoids, tannins, proanthocyanidins, phytosterols, carotenoids, and vitamin E. It is often used in skincare products aimed at soothing and healing irritated skin.
Euterpe Oleracea Fruit Extract
Est. %0.3
Function
Origin
Euterpe Oleracea Fruit ExtractAn antioxidant extract obtained from the fruits of the acai palm. It has a high content of anthocyanins, responsible for the dark purple color, as well as other antioxidant phenolic compounds.
Punica Granatum Extract
Est. %0.3
Function
Origin
Punica Granatum ExtractAn extract made from pomegranate fruit. The fleshy and juicy part of the fruit mainly contains antioxidant red pigments and polyphenols. The rinds contain large amounts of tannins, which are astringent and leave the skin feeling tightened and refreshed.
Vaccinium Angustifolium (Blueberry) Fruit Juice
Est. %0.3
Function
Origin
Vaccinium Angustifolium (Blueberry) Fruit Juice
Rosa Damascena Flower Oil
Est. %0.3
Function
Origin
Rosa Damascena Flower OilAlso known as Damask rose oil, it is one of the most precious and expensive essential oils in the world obtained from the petals of the Damask rose. It is used in skincare as a luxurious fragrance.
Methyldihydrojasmonate
Est. %0.3
Function
Origin
Methyldihydrojasmonate
Ethylene Brassylate
Est. %0.3
Function
Origin
Ethylene BrassylateA synthetic fragrance ingredient known for its musky scent. Like most fragrance ingredients, it can be irritating.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
PEG-75 Stearate
Est. %0.3
Function
Origin
PEG-75 Stearate
Steareth-20
Est. %0.3
Function
Origin
Steareth-20A white to light brown reaction product of a clear gas and stearyl alcohol. Like the other steareth ingredients, steareth-20 is a waxy emulsifier that can help to form a stable emulsion, even in extreme conditions.
Ceteth-20
Est. %0.3
Function
Origin
Ceteth-20A very mild but effective polyethylene-based cleanser and emulsifier.
Triethyl Citrate
Est. %0.3
Function
Origin
Triethyl Citrate
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Magnesium Aluminum Silicate
Est. %0.3
Function
Origin
Magnesium Aluminum SilicateA naturally occurring clay that is hygroscopic, which means that it easily absorbs water. This ingredient is thus commonly used as an absorbent and emulsion stabilizer. It also modifies slip by improving the spreadability of the products it is used in.
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Est. %0.3
Function
Origin
Pentaerythrityl Tetra-di-t-butyl HydroxyhydrocinnamateAn antioxidant that protects vulnerable ingredients from the damage caused by ultraviolet radiation, which can also lead to the generation of damaging free radical species.
Sodium Bisulfite
Est. %0.3
Function
Origin
Sodium BisulfiteAn inorganic salt that kills bacteria and protects against oxidation.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Caramel
Est. %0.3
Function
Origin
CaramelA natural ingredient that is derived from the heat treatment of table sugar. Caramel is used in skincare as a natural colorant that can create transparent, dark brown solutions. It also works as a fragrance, where it provides a sweet, sugary scent.
Yellow 5 (CI 19140)
Est. %0.3
Function
Origin
Yellow 5 (CI 19140)A bright yellow colorant that is often also listed as FD&C Yellow 5.