Cetaphil Healthy Renew Purified Peptides Eye Gel Serum

Cetaphil Healthy Renew Purified Peptides Eye Gel Serum
5.6
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.2 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Does Cetaphil Healthy Renew Purified Peptides Eye Gel Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Cetaphil Healthy Renew Purified Peptides Eye Gel Serum:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.6 out of 10.
  • Some anti-wrinkle efficacy: Cetaphil Healthy Renew Purified Peptides Eye Gel Serum has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Soothing: Cetaphil Healthy Renew Purified Peptides Eye Gel Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, Cetaphil Healthy Renew Purified Peptides Eye Gel Serum is quite moisturizing, with a moisturizing rating of 5.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈7.5%), Propanediol (est. ≈5.0%) and Panthenol (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, Cetaphil Healthy Renew Purified Peptides Eye Gel Serum has a slight anti-wrinkle rating of 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Cetaphil Healthy Renew Purified Peptides Eye Gel Serum also contains Adenosine, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Adenosine provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Cetaphil Healthy Renew Purified Peptides Eye Gel Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing and calming potential

Based on the ingredient list analysis, Cetaphil Healthy Renew Purified Peptides Eye Gel Serum is rich (> 5%) in soothing ingredients, particularly Panthenol (est. ≈3.0%) and Niacinamide (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
65
7.5
5
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Propanediol
Function:
Origin:
Panthenol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Niacinamide
Function:
Origin:
C13-15 Alkane
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Cocos Nucifera (Coconut) Oil
Function:
Origin:
Sodium Polyacryloyldimethyl Taurate
Function:
Origin:
Hydrogenated Polydecene
Function:
Origin:
Silica
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Vinyl Dimethicone
Function:
Origin:
C14-22 Alcohols
Function:
Origin:
Leontopodium Alpinum Extract
Function:
Origin:
Polyglyceryl-2 Stearate
Function:
Origin:
Polyacrylate-13
Function:
Origin:
C12-20 Alkyl Glucoside
Function:
Origin:
Oryza Sativa (Rice) Lees Extract
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Polyisobutene
Function:
Origin:
Hydrolyzed Soy Flour
Function:
Origin:
Adenosine
Function:
Origin:
Dimethicone/Vinyl Dimethicone Crosspolymer
Function:
Origin:
Butylene Glycol
Function:
Origin:
Trisodium Ethylenediamine Disuccinate
Function:
Origin:
Acacia Senegal Gum
Function:
Origin:
Citric Acid
Function:
Origin:
Agar
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Polysorbate 20
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Xanthan Gum
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Buddleja Davidii Extract
Function:
Origin:
Thymus Vulgaris (Thyme) Extract
Function:
Origin:

Ratings

All humectants
18.7
7.5
5
3
2
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.3
1.3
1.0
Benchmark
20
Moisturizing rating
5.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 18.7 10
10.0
7.5
5
3
2
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.3 20
1.2
1.3
1.0
Moisturizing rating
5.6
Ingredient Est. % Benchmark Humectancy
7.5
5
3
2
0.3
0.3
0.3
0.3
All humectants 18.7 10
10
All humectants
18.7
7.5
5
3
2
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.3
1
All occlusives 2.3 20
1.2
All occlusives
2.3
1.3
1.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
n/a
- 0.3 -
Total
3
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.5 3 Rich in antioxidants
All antioxidants
3.5
Niacinamide
2
Tocopheryl Acetate
0.3
Leontopodium Alpinum Extract
0.3
Sodium Hyaluronate
0.3
Buddleja Davidii Extract
0.3
Thymus Vulgaris (Thyme) Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
2
0.3
All soothing 5.3 5 Rich in soothing
All soothing
5.3
3
2
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %7.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Propanediol
Est. %5
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Panthenol
Est. %3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
1,2-Hexanediol
Est. %2.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

C13-15 Alkane
Est. %1.5
Function
Origin
C13-15 Alkane
Butyrospermum Parkii (Shea) Butter
Est. %1.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Cocos Nucifera (Coconut) Oil
Est. %1
Function
Origin
Cocos Nucifera (Coconut) OilA famous occlusive moisturizing and emollient oil. It is derived from coconuts and may give a product a lovely coconut scent. Coconut oil is listed as a common comedogenic ingredient by acne.org.
Sodium Polyacryloyldimethyl Taurate
Est. %0.3
Function
Origin
Sodium Polyacryloyldimethyl Taurate
Hydrogenated Polydecene
Est. %0.3
Function
Origin
Hydrogenated PolydeceneA clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Silica
Est. %0.3
Function
Origin
SilicaA widely used cosmetic ingredient with the same chemical composition as the sand found on beaches. A common function of silica is its ability to control viscosity. In certain chemical forms, it can effectively thicken cream-style products.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Vinyl Dimethicone
Est. %0.3
Function
Origin
Vinyl Dimethicone
C14-22 Alcohols
Est. %0.3
Function
Origin
C14-22 AlcoholsA naturally-derived emulsion stabilizer that has a light feel. It is not a drying alcohol, in fact the emulsions it helps create can make the skin feel soft and cushioned.
Leontopodium Alpinum Extract
Est. %0.3
Function
Origin
Leontopodium Alpinum ExtractAn extract from a beautiful alpine plant called Edelweiss. It contains a rare compound called leontopodic acid with antioxidant, antibacterial, and anti-inflammatory properties.
Polyglyceryl-2 Stearate
Est. %0.3
Function
Origin
Polyglyceryl-2 Stearate
Polyacrylate-13
Est. %0.3
Function
Origin
Polyacrylate-13A synthetic, film-forming ingredient that creates a network around other ingredients in the formula and protects them from being easily washed away.
C12-20 Alkyl Glucoside
Est. %0.3
Function
Origin
C12-20 Alkyl Glucoside
Oryza Sativa (Rice) Lees Extract
Est. %0.3
Function
Origin
Oryza Sativa (Rice) Lees Extract
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Stearyl Alcohol
Est. %0.3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Polyisobutene
Est. %0.3
Function
Origin
PolyisobuteneA highly viscous liquid that is used in lip gloss formulations to prolong wear time and add shimmer. Polyisobutene dramatically increases the thickness of skincare products it is added to.
Hydrolyzed Soy Flour
Est. %0.3
Function
Origin
Hydrolyzed Soy Flour
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Dimethicone/Vinyl Dimethicone Crosspolymer
Est. %0.3
Function
Origin
Dimethicone/Vinyl Dimethicone CrosspolymerThis ingredient can refer to several kinds of dimethicone crosspolymers. Like other silicones, it makes products feel slippery and non-greasy but can also increase the thickness or improve the water-resistance of a formula.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Trisodium Ethylenediamine Disuccinate
Est. %0.3
Function
Origin
Trisodium Ethylenediamine DisuccinateA chelating agent that disables harmful heavy metal ions present in skincare.
Acacia Senegal Gum
Est. %0.3
Function
Origin
Acacia Senegal GumA formula helper, also known as gum arabic, derived from the African Acacia tree. It is used in skincare formulas due to its good adhesive and film-forming properties.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Agar
Est. %0.3
Function
Origin
AgarA multifunctional jelly derived from red algae that can thicken water-based products.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Buddleja Davidii Extract
Est. %0.3
Function
Origin
Buddleja Davidii ExtractAn extract of summer lilac with antioxidant and anti-inflammatory compounds such as iridoids, various terpenes, flavonoids, and phenolic acids. More research is needed in order to evaluate its functions.
Thymus Vulgaris (Thyme) Extract
Est. %0.3
Function
Origin
Thymus Vulgaris (Thyme) ExtractDerived from thyme, this antioxidant, antiseptic and fragrant extract consists mainly of thyme essential oil (with its spicy herbal scent), flavonoids, terpenes, and organic acids.