SkinMedica GlyPro Renewal Cream

SkinMedica GlyPro Renewal Cream
5.0
/ 10
Moisturizing
9.0 Humectancy icon Humectancy
1.1 Occlusivity icon Occlusivity
1.5Anti-wrinkle icon/ 10
Anti-wrinkle
$$$$

Review

Results you may expect from using SkinMedica GlyPro Renewal Cream:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using SkinMedica GlyPro Renewal Cream:

  • Moderate moisturizing. It has a moisturizing rating of 5.0 out of 10.
  • Little anti-wrinkle effect: SkinMedica GlyPro Renewal Cream has an anti-wrinkle rating of 1.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

How moisturizing is it?

Quite moisturizing: SkinMedica GlyPro Renewal Cream has a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.1 out of 10 and a very high humectancy of 9.0 out of 10, primarily due to the high content of Glycerin (est. ≈4.0%) and Pentylene Glycol (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, SkinMedica GlyPro Renewal Cream has a minimal anti-wrinkle rating of 1.5 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈20.0%),
 highly effective in peelings, yet with below-average anti-wrinkle efficacy when used in leave-on skincare products.
 
Among others, SkinMedica GlyPro Renewal Cream also contains some ingredients marketed as effective in reducing wrinkles, specifically Dipeptide Diaminobutyroyl Benzylamide Diacetate, Olea Europaea (Olive) Leaf Extract, and Magnesium Ascorbyl Phosphate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
50
20
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
9.0
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.2
1.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.0 10
9.0
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.2 20
1.1
1.3
0.3
0.3
0.3
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 9.0 10
9
All humectants
9.0
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.3
0.3
0.3
0.3
All occlusives 2.2 20
1.1
All occlusives
2.2
1.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 20 1.5
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
1.5
Glycolic Acid
1.5
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
20
Dipeptide Diaminobutyroyl Benzylamide Diacetate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Olea Europaea (Olive) Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Magnesium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
1.5
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 1.8 3 No
All antioxidants
1.8
Algae Extract
0.3
Sodium Hyaluronate
0.3
Olea Europaea (Olive) Leaf Extract
0.3
Superoxide Dismutase
0.3
Magnesium Ascorbyl Phosphate
0.3
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %50
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycolic Acid
Est. %20
Function
Origin

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Cyclopentasiloxane
Est. %6
Function
Origin
A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Glycerin
Est. %4
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Bis-Hydroxyethoxypropyl Dimethicone
Est. %3
Function
Origin
Description is coming soon
Cetearyl Alcohol
Est. %2.5
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Pentylene Glycol
Est. %2
Function
Origin

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Stearyl Alcohol
Est. %1.5
Function
Origin
A natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Caprylic/Capric Triglyceride
Est. %1.3
Function
Origin
A natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Ceresin
Est. %1
Function
Origin
A naturally-derived wax often used to create solid products.
Saccharide Isomerate
Est. %0.3
Function
Origin
A naturally-derived humectant that provides moisturization at low levels and is less sticky than other humectants like glycerin.
Cyclohexasiloxane
Est. %0.3
Function
Origin
A clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Cetearyl Glucoside
Est. %0.3
Function
Origin
An emulsifier that creates stable mixtures of oil in water that feel soft and spread easily. Cetearyl glucoside is sold with cetearyl alcohol as an emulsifier blend and also provides some body to the formula.
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Est. %0.3
Function
Origin
A synthetically made peptide similar to the proteins in viper venom. Similarly to Botox, it works by inhibiting contractions of mimic muscles, thereby offering a short-term reduction in mimic wrinkles.
Algae Extract
Est. %0.3
Function
Origin
The name describes any extract made from any kind of algae. Algae extracts are moisturizing humectants – the gelatin-like polysaccharides bind and retain water, thereby hydrating the skin. Algae is a rich source of emollient and antioxidant compounds.
Glyceryl Stearate
Est. %0.3
Function
Origin
An emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %0.3
Function
Origin
This surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Octyldodecanol
Est. %0.3
Function
Origin
An emollient fatty alcohol that spreads easily without leaving a greasy residue on the skin. It is also used as a solvent and dispersing agent for other ingredients.
Irvingia Gabonensis Kernel Butter
Est. %0.3
Function
Origin
Description is coming soon
Hydrogenated Coco-Glycerides
Est. %0.3
Function
Origin
A vegetable-derived stabilized oily solid that can act as an alternative to petroleum jelly. Like petroleum jelly it can bring creaminess to a formula.
Magnesium Aluminum Silicate
Est. %0.3
Function
Origin
A naturally occurring clay that is hygroscopic, which means that it easily absorbs water. This ingredient is thus commonly used as an absorbent and emulsion stabilizer. It also modifies slip by improving the spreadability of the products it is used in.
Polyacrylate-13
Est. %0.3
Function
Origin
A synthetic, film-forming ingredient that creates a network around other ingredients in the formula and protects them from being easily washed away.
Polyisobutene
Est. %0.3
Function
Origin
A highly viscous liquid that is used in lip gloss formulations to prolong wear time and add shimmer. Polyisobutene dramatically increases the thickness of skincare products it is added to.
Polysorbate 20
Est. %0.3
Function
Origin
A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Stearic Acid
Est. %0.3
Function
Origin
A saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Sodium PCA
Est. %0.3
Function
Origin
One of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Urea
Est. %0.3
Function
Origin
Urea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Trehalose
Est. %0.3
Function
Origin
A sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Polyquaternium-51
Est. %0.3
Function
Origin
A biocompatible phospholipid copolymer that is designed to mimic the lipid-based cell membrane found in human skin. Its main function is as a humectant moisturizer.
Sodium Hyaluronate
Est. %0.3
Function
Origin

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Hydroxyethylcellulose
Est. %0.3
Function
Origin
A naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Dimethicone Crosspolymer
Est. %0.3
Function
Origin
A group of ingredients that are typically added to skincare products to adjust the formula. Dimethicone Crosspolymers stabilize a formula, regulate its thickness and consistency and give the product a velvety feel.
Olea Europaea (Olive) Leaf Extract
Est. %0.3
Function
Origin
An antioxidant and fragrant extract from the leaves of the olive tree. It contains a promising anti-aging compound called Oleuropein, and a prospective anti-pigment compound called Cornoside.
Superoxide Dismutase
Est. %0.3
Function
Origin
Description is coming soon
Magnesium Ascorbyl Phosphate
Est. %0.3
Function
Origin
One of the best-researched derivatives of vitamin C. It is more resistant to light and air and retains all the properties of ascorbic acid – antioxidant, collagen-boosting, and anti-pigmentation, but with less irritation.
Tocopherol
Est. %0.3
Function
Origin

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Hexylene Glycol
Est. %0.3
Function
Origin
A multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Triacetin
Est. %0.3
Function
Origin
Description is coming soon
Aluminum Hydroxide
Est. %0.3
Function
Origin
A white mineral powder, also known as alumina, that is derived from aluminum metal. It is frequently used as an abrasive in exfoliating products and as a thickener. Aluminum oxide is also a great opacifier.
Ammonium Hydroxide
Est. %0.3
Function
Origin
A weakly basic ingredient that can adjust pH to a higher level.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Ethylhexylglycerin
Est. %0.3
Function
Origin
A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Potassium Sorbate
Est. %0.3
Function
Origin
A preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.