SkinMedica GlyPro Antioxidant Serum

SkinMedica GlyPro Antioxidant Serum
4.4
/ 10
Moisturizing
7.9 Humectancy icon Humectancy
1.0 Occlusivity icon Occlusivity
1.5Anti-wrinkle icon/ 10
Anti-wrinkle
$$$$

Review

Results you may expect from using SkinMedica GlyPro Antioxidant Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using SkinMedica GlyPro Antioxidant Serum:

  • Moderate moisturizing. It has a moisturizing rating of 4.4 out of 10.
  • Little anti-wrinkle effect: SkinMedica GlyPro Antioxidant Serum has an anti-wrinkle rating of 1.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

How moisturizing is it?

Quite moisturizing: SkinMedica GlyPro Antioxidant Serum has a moisturizing rating of 4.4 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.0 out of 10 and a high humectancy of 7.9 out of 10, primarily due to the high content of Glycerin (est. ≈4.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, SkinMedica GlyPro Antioxidant Serum has a minimal anti-wrinkle rating of 1.5 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈6.0%),
 highly effective in peelings, yet with below-average anti-wrinkle efficacy when used in leave-on skincare products.
 
Among others, SkinMedica GlyPro Antioxidant Serum also contains Olea Europaea (Olive) Leaf Extract, an ingredient marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Olea Europaea (Olive) Leaf Extract provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
7.9
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.0
2.0
Benchmark
20
Moisturizing rating
4.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.9 10
7.9
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.0 20
1.0
2.0
Moisturizing rating
4.4
Ingredient Est. % Benchmark Humectancy
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 7.9 10
7.9
All humectants
7.9
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2
All occlusives 2.0 20
1.0
All occlusives
2.0
2.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 6 1.5
n/a
- 0.3 -
Total
1.5
Glycolic Acid
1.5
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
6
Olea Europaea (Olive) Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
1.5
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 2.1 3 No
All antioxidants
2.1
Camellia Oleifera Leaf Extract
0.3
Punica Granatum Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Aloe Barbadensis Leaf Extract
0.3
Sodium Hyaluronate
0.3
Mannitol
0.3
Olea Europaea (Olive) Leaf Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
0.3
All soothing 1.5 5 No
All soothing
1.5
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycolic Acid
Est. %6
Function
Origin

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Glycerin
Est. %4
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Isononyl Isononanoate
Est. %3
Function
Origin
An ester of a branched fatty acid with a branched fatty alcohol. It is an easily spreadable emollient that has a silky, dry, non-greasy feel on the skin.
Phenyl Trimethicone
Est. %2
Function
Origin
A silicone fluid that is used as an occlusive moisturizer. It applies smoothly to the skin and reduces the tack associated with organic oils.
Cyclomethicone
Est. %1.5
Function
Origin
A blend of emollient silicones that leaves a smooth and non-greasy after-feel. Unlike other types of oils, it does not leave any residue on the skin, which is part of what makes it so popular.
Cassia Angustifolia Seed Polysaccharide
Est. %1.3
Function
Origin
An ingredient obtained from a plant commonly called Senna. Polysaccharides are known to create a mild humectant film on the skin, helping to retain moisture. It can also make the skin appear smooth and contribute to a glowing look.
Bis-Hydroxyethoxypropyl Dimethicone
Est. %1
Function
Origin
Description is coming soon
C14-22 Alcohols
Est. %0.3
Function
Origin
A naturally-derived emulsion stabilizer that has a light feel. It is not a drying alcohol, in fact the emulsions it helps create can make the skin feel soft and cushioned.
C12-20 Alkyl Glucoside
Est. %0.3
Function
Origin
Description is coming soon
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Camellia Oleifera Leaf Extract
Est. %0.3
Function
Origin
An emollient extract derived from the leaves of the Tea-oil Camellia, which is native to Southeast Asia. It contains astringent and wound-healing tannins that create a tightening feeling on the skin and can speed up the healing process of small cuts.
Punica Granatum Extract
Est. %0.3
Function
Origin
An extract made from pomegranate fruit. The fleshy and juicy part of the fruit mainly contains antioxidant red pigments and polyphenols. The rinds contain large amounts of tannins, which are astringent and leave the skin feeling tightened and refreshed.
Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
An extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Anthemis Nobilis Flower Extract
Est. %0.3
Function
Origin
An antioxidant and soothing flower extract derived from Roman chamomile. It contains an essential oil that gives it a sweet and floral aroma.
Aloe Barbadensis Leaf Extract
Est. %0.3
Function
Origin
Derived from Aloe vera leaves, this moisturizing humectant, soothing, and antioxidant extract is commonly used in products targeting eczema, sunburn, or dermatitis. It soothes the skin and reduces the signs of inflammation and sensitivity.
Stevia Rebaudiana Leaf/Stem Extract
Est. %0.3
Function
Origin
An extract derived from stevia, a natural sweetener. It adds flavor and fragrance to skin and lip care products.
Sodium PCA
Est. %0.3
Function
Origin
One of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Urea
Est. %0.3
Function
Origin
Urea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Trehalose
Est. %0.3
Function
Origin
A sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Polyquaternium-51
Est. %0.3
Function
Origin
A biocompatible phospholipid copolymer that is designed to mimic the lipid-based cell membrane found in human skin. Its main function is as a humectant moisturizer.
Sodium Hyaluronate
Est. %0.3
Function
Origin

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Cetearyl Alcohol
Est. %0.3
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Ceteareth-33
Est. %0.3
Function
Origin
Description is coming soon
Mannitol
Est. %0.3
Function
Origin
A sweet-tasting, sugar-derived, humectant alcohol that can stabilize a skincare formula and offer some antioxidant and soothing properties.
Cyclodextrin
Est. %0.3
Function
Origin
A naturally derived ingredient with the ability to absorb other compounds and remove harmful metal ions from water.
Yeast Extract
Est. %0.3
Function
Origin
Also labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
Disodium Succinate
Est. %0.3
Function
Origin
Description is coming soon
Olea Europaea (Olive) Leaf Extract
Est. %0.3
Function
Origin
An antioxidant and fragrant extract from the leaves of the olive tree. It contains a promising anti-aging compound called Oleuropein, and a prospective anti-pigment compound called Cornoside.
Polysilicone-11
Est. %0.3
Function
Origin
A synthetic rubber-like substance of the silicone family that has no color or distinct scent. These are large molecules that cannot penetrate the skin but instead create a thin silky film on the skin's surface.
Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Polyacrylate-13
Est. %0.3
Function
Origin
A synthetic, film-forming ingredient that creates a network around other ingredients in the formula and protects them from being easily washed away.
Polyisobutene
Est. %0.3
Function
Origin
A highly viscous liquid that is used in lip gloss formulations to prolong wear time and add shimmer. Polyisobutene dramatically increases the thickness of skincare products it is added to.
Polysorbate 20
Est. %0.3
Function
Origin
A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Hexylene Glycol
Est. %0.3
Function
Origin
A multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Triacetin
Est. %0.3
Function
Origin
Description is coming soon
Ammonium Hydroxide
Est. %0.3
Function
Origin
A weakly basic ingredient that can adjust pH to a higher level.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Ethylhexylglycerin
Est. %0.3
Function
Origin
A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Potassium Sorbate
Est. %0.3
Function
Origin
A preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.