SkinBetter Science Interufse Intensive Treatment Lines

SkinBetter Science Interufse Intensive Treatment Lines
4.2
/ 10
Moisturizing
7.0 Humectancy icon Humectancy
1.3 Occlusivity icon Occlusivity
0.6Anti-wrinkle icon/ 10
Anti-wrinkle

Review

Does SkinBetter Science Interufse Intensive Treatment Lines work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using SkinBetter Science Interufse Intensive Treatment Lines:

  • Moderate moisturizing. It has a moisturizing rating of 4.2 out of 10.
  • Little anti-wrinkle effect: SkinBetter Science Interufse Intensive Treatment Lines has an anti-wrinkle rating of 0.6 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

Lightweight moisturizer well-suited for oily skin and a humectant enhancement for any skincare routine

According to CreamScan analysis, SkinBetter Science Interufse Intensive Treatment Lines is quite moisturizing, with a moisturizing rating of 4.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.3 out of 10 and a high humectancy of 7.0 out of 10, primarily due to the high content of Glycerin (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It can also be a good option for people with normal skin who prefer lightweight moisturizers.

Such a humectant engancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Little anti-wrinkle efficacy

According to CreamScan analysis, SkinBetter Science Interufse Intensive Treatment Lines has a minimal anti-wrinkle rating of 0.6 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Ascorbyl Tetraisopalmitate (est. ≈0.3%), 
 the only derivative of ascorbic acid with solid evidence of anti-wrinkle efficacy. A single clinical study involving 23 participants (Mariko et al.) demonstrated that a cream with 1% ATIP reduced the average depth of periorbital wrinkles by 6% after 8 weeks of use, compared to a vehicle (the same formulation without ATIP).
 
Among others, SkinBetter Science Interufse Intensive Treatment Lines also contains some ingredients often marketed as effective in reducing wrinkles, specifically Acetyl Glucosamine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, and Dipeptide Diaminobutyroyl Benzylamide Diacetate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
C12-15 Alkyl Benzoate
Function:
Origin:
Glycerin
Function:
Origin:
PEG-16 Macadamia Glycerides
Function:
Origin:
Dimethicone
Function:
Origin:
Acetyl Glucosamine
Function:
Origin:
Alcohol Denat.
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Sodium Citrate
Function:
Origin:
Ascorbyl Tetraisopalmitate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Glycine
Function:
Origin:
Hydroxyproline
Function:
Origin:
Proline
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Hexapeptide-48 HCl
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:
Pisum Sativum (Pea) Extract
Function:
Origin:
Glycine Soja (Soybean) Seed Extract
Function:
Origin:
Glucosamine HCl
Function:
Origin:
Ophiopogon Japonicus Root Extract
Function:
Origin:
Bambusa Vulgaris Leaf/Stem Extract
Function:
Origin:
Hydrolyzed Lupine Protein
Function:
Origin:
Oleic Acid
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
C18-36 Acid Glycol Ester
Function:
Origin:
PEG-7 Trimethylolpropane Coconut Ether
Function:
Origin:
Sorbitan Laurate
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Polyisobutene
Function:
Origin:
C18-36 Acid Triglyceride
Function:
Origin:
Carbomer
Function:
Origin:
Acrylates Copolymer
Function:
Origin:
Citric Acid
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
7.0
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.6
2.0
0.3
0.3
Benchmark
20
Moisturizing rating
4.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.0 10
7.0
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.6 20
1.3
2.0
0.3
0.3
Moisturizing rating
4.2
Ingredient Est. % Benchmark Humectancy
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 7.0 10
7
All humectants
7.0
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2
0.3
0.3
All occlusives 2.6 20
1.3
All occlusives
2.6
2.0
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2 /10 1 0.3 0.6
n/a
- 1.5 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.6
Ascorbyl Tetraisopalmitate
0.6
Ingredient anti-wrinkle power
2 /10
when present at, %
1
in this formula, est. %
0.3
Acetyl Glucosamine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dipeptide Diaminobutyroyl Benzylamide Diacetate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.6
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
All antioxidants 1.2 3 No
All antioxidants
1.2
Ascorbyl Tetraisopalmitate
0.3
Sodium Hyaluronate
0.3
Glycine Soja (Soybean) Seed Extract
0.3
Ophiopogon Japonicus Root Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
C12-15 Alkyl Benzoate
Est. %6
Function
Origin
C12-15 Alkyl BenzoateA synthetic emollient ester. It works to improve the appearance of the skin by filling in the microcracks on the surface, thereby making the skin appear softer and smoother. It imparts a lightweight, velvety feel.
Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

PEG-16 Macadamia Glycerides
Est. %3
Function
Origin
PEG-16 Macadamia Glycerides
Dimethicone
Est. %2
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Acetyl Glucosamine
Est. %1.5
Function
Origin
Acetyl GlucosamineA body-natural amino-saccharide used in skincare as an anti-pigment ingredient. Some other benefits of acetyl glucosamine include decreased skin flakiness, improved wound healing, and even a slight reduction in facial wrinkles.
Alcohol Denat.
Est. %1.3
Function
Origin
Alcohol Denat.

Denatured alcohol is ethanol that contains additives that make it unsafe to consume. It is mainly used as a solvent and an antimicrobial agent. A major drawback to alcohol denat. is that it dries out the skin.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %1
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Ascorbyl Tetraisopalmitate
Est. %0.3
Function
Origin
Ascorbyl Tetraisopalmitate

Ascorbyl Tetraisopalmitate (ATIP) is an oil-soluble derivative of ascorbic acid, or vitamin C. It is more stable than ascorbic acid, with studies supporting its collagen-boosting and anti-pigment effects.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Hydroxyproline
Est. %0.3
Function
Origin
HydroxyprolineAn amino acid that may promote collagen synthesis.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Hexapeptide-48 HCl
Est. %0.3
Function
Origin
Hexapeptide-48 HCl
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Dipeptide Diaminobutyroyl Benzylamide Diacetate
Est. %0.3
Function
Origin
Dipeptide Diaminobutyroyl Benzylamide DiacetateA synthetically made peptide similar to the proteins in viper venom. Similarly to Botox, it works by inhibiting contractions of mimic muscles, thereby offering a short-term reduction in mimic wrinkles.
Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.
Pisum Sativum (Pea) Extract
Est. %0.3
Function
Origin
Pisum Sativum (Pea) ExtractAn extract derived from peas that contains many proteins with humectant moisturizing properties. Patents have claimed that it is able to stimulate cell renewal and increase melanin production.
Glycine Soja (Soybean) Seed Extract
Est. %0.3
Function
Origin
Glycine Soja (Soybean) Seed ExtractAn antioxidant, soothing, and wound healing extract derived from soybeans. Soybeans are a famous source of phytoestrogens - plant compounds that have a similar effect to steroid hormones.
Glucosamine HCl
Est. %0.3
Function
Origin
Glucosamine HClA naturally occurring compound that reduces static and lowers the pH of skincare products.
Ophiopogon Japonicus Root Extract
Est. %0.3
Function
Origin
Ophiopogon Japonicus Root ExtractA moisturizing extract derived from the roots of the dwarf lilyturf, also known as mondo grass. It is rich in humectant polysaccharides and contains anti-inflammatory and antioxidant compounds.
Bambusa Vulgaris Leaf/Stem Extract
Est. %0.3
Function
Origin
Bambusa Vulgaris Leaf/Stem Extract
Hydrolyzed Lupine Protein
Est. %0.3
Function
Origin
Hydrolyzed Lupine Protein
Oleic Acid
Est. %0.3
Function
Origin
Oleic AcidAn omega-9 fatty acid commonly found in vegetable oils. It is occlusive moisturizing, emollient and emulsifying.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
C18-36 Acid Glycol Ester
Est. %0.3
Function
Origin
C18-36 Acid Glycol Ester
PEG-7 Trimethylolpropane Coconut Ether
Est. %0.3
Function
Origin
PEG-7 Trimethylolpropane Coconut Ether
Sorbitan Laurate
Est. %0.3
Function
Origin
Sorbitan LaurateSorbitan laurate is a sugar-based emulsifier similar to sucrose palmitate. It keeps oil broken into small droplets throughout water because of its chemical shape and nature (this is how most oil-in-water emulsifiers work by the way). These kinds of emulsifiers are mild enough to even be used in food preparations.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Polyisobutene
Est. %0.3
Function
Origin
PolyisobuteneA highly viscous liquid that is used in lip gloss formulations to prolong wear time and add shimmer. Polyisobutene dramatically increases the thickness of skincare products it is added to.
C18-36 Acid Triglyceride
Est. %0.3
Function
Origin
C18-36 Acid Triglyceride
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Acrylates Copolymer
Est. %0.3
Function
Origin
Acrylates CopolymerA highly functional synthetic ingredient that forms a protective layer on the skin and reduces static buildup. It gives an emollient feel to the product, including a silky after-feel.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.