Sesderma C Vit 5 Liposomal Serum Review

Sesderma C Vit 5 Liposomal Serum
3.9
/ 10
Moisturizing
7.8 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Ingredients

Sesderma C Vit 5 Liposomal Serum Ingredients

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Full Ingredient List (INCI):

Water, Glycerin, Phosphatidylcholine, Polymethyl Methacrylate, PEG-40 Hydrogenated Castor Oil, Ammonium Polyacryloyldimethyl Taurate, Alcohol, Ascorbyl Glucoside, Benzoic Acid, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Caesalpinia Spinosa Fruit Extract, Caprylyl Glycol, Centella Asiatica Extract, Yellow 6 (CI 15985), Citral, Citronellyl Methylcrotonate, Limonene, Disodium EDTA, Hydrochloric Acid, Kappaphycus Alvarezii Extract, Linalool, Magnesium Ascorbyl Phosphate, Methylsilanol Mannuronate, Fragrance, Phenoxyethanol, Polysorbate 20, Polysorbate 60, Potassium Sorbate, Propylene Glycol, Sodium Ascorbate, Sodium Chloride, Sodium Cholate, Sodium Hyaluronate, Sodium Hydroxide, Soluble Proteoglycan, Sorbic Acid, Tocopheryl Acetate, Triethyl Citrate, Trisodium Ascorbyl Palmitate Phosphate, Xanthan Gum
Review

Does Sesderma C Vit 5 Liposomal Serum Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Sesderma C Vit 5 Liposomal Serum has to offer:
 
✅ Light moisturizing. It has a moisturizing rating of 3.9 out of 10.
✅ Antioxidant protection

  

Key Benefits of Sesderma C Vit 5 Liposomal Serum

 
These are the key benefits you can expect from using Sesderma C Vit 5 Liposomal Serum:
 

🔵 Lightweight Purely Humectant Moisturizer Well-Suited for Oily Skin

According to CreamScan analysis, Sesderma C Vit 5 Liposomal Serum is lightly moisturizing, with a moisturizing rating of 3.9 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a high humectancy of 7.8 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Enhancement for Any Skincare Routine

But it’s not limited to oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Sesderma C Vit 5 Liposomal Serum is rich (> 3%) in antioxidants, specifically Ascorbyl Glucoside (est. ≈1.0%), Caesalpinia Spinosa Fruit Extract (est. ≈0.3%), Centella Asiatica Extract (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Sesderma C Vit 5 Liposomal Serum

 
CreamScan identified a few things to consider before adding Sesderma C Vit 5 Liposomal Serum to your skincare routine:
 

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Sesderma C Vit 5 Liposomal Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

⚠️ Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Sesderma C Vit 5 Liposomal Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains some ingredients often marketed as effective in reducing wrinkles, specifically Ascorbyl Glucoside, Centella Asiatica Extract, Magnesium Ascorbyl Phosphate, and Sodium Ascorbate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. 

While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.

Therefore, these ingredients do not generate the anti-wrinkle rating.

📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Sesderma C Vit 5 Liposomal Serum

 
Here’s an overview of the pros and cons of Sesderma C Vit 5 Liposomal Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing well-suited for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
⚠️ Questionable anti-wrinkle efficacy
   

Summary: Sesderma C Vit 5 Liposomal Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Sesderma C Vit 5 Liposomal Serum
, when used alone, delivers lightweight, humectant-rich moisturizing that is well-suited for oily skin. As part of a moisturizing routine, it provides a humectant enhancement, beneficial for all skin types.
 
With its high antioxidant content, Sesderma C Vit 5 Liposomal Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Sesderma C Vit 5 Liposomal Serum worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
If one of your main reasons for considering Sesderma C Vit 5 Liposomal Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, its anti-wrinkle efficacy is questionable. None of the ingredients in this product provide substantial evidence of their anti-wrinkle efficacy according to CreamScan Research Evaluation Standards.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.15
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Phosphatidylcholine
Function:
Origin:
Polymethyl Methacrylate
Function:
Origin:
PEG-40 Hydrogenated Castor Oil
Function:
Origin:
Ammonium Polyacryloyldimethyl Taurate
Function:
Origin:
Alcohol
Function:
Origin:
Ascorbyl Glucoside
Function:
Origin:
Benzoic Acid
Function:
Origin:
Bis-PEG-18 Methyl Ether Dimethyl Silane
Function:
Origin:
Butylene Glycol
Function:
Origin:
Caesalpinia Spinosa Fruit Extract
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Yellow 6 (CI 15985)
Function:
Origin:
Citral
Function:
Origin:
Citronellyl Methylcrotonate
Function:
Origin:
Limonene
Function:
Origin:
Disodium EDTA
Function:
Origin:
Hydrochloric Acid
Function:
Origin:
Kappaphycus Alvarezii Extract
Function:
Origin:
Linalool
Function:
Origin:
Magnesium Ascorbyl Phosphate
Function:
Origin:
Methylsilanol Mannuronate
Function:
Origin:
Fragrance
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Polysorbate 20
Function:
Origin:
Polysorbate 60
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Propylene Glycol
Function:
Origin:
Sodium Ascorbate
Function:
Origin:
Sodium Chloride
Function:
Origin:
Sodium Cholate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Soluble Proteoglycan
Function:
Origin:
Sorbic Acid
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Triethyl Citrate
Function:
Origin:
Trisodium Ascorbyl Palmitate Phosphate
Function:
Origin:
Xanthan Gum
Function:
Origin:

Ratings

All humectants
7.8
6
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
3.9
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.8 10
7.8
6
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
3.9
Ingredient Est. % Benchmark Humectancy
6
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 7.8 10
7.8
All humectants
7.8
6
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 1 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Ascorbyl Glucoside
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Magnesium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Sodium Ascorbate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.4 3 Rich in antioxidants
All antioxidants
3.4
Ascorbyl Glucoside
1
Caesalpinia Spinosa Fruit Extract
0.3
Centella Asiatica Extract
0.3
Kappaphycus Alvarezii Extract
0.3
Magnesium Ascorbyl Phosphate
0.3
Sodium Ascorbate
0.3
Sodium Hyaluronate
0.3
Tocopheryl Acetate
0.3
Trisodium Ascorbyl Palmitate Phosphate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Phosphatidylcholine
Est. %4
Function
Origin
PhosphatidylcholineA special emulsifying lipid used to create delivery spheres called liposomes.
Polymethyl Methacrylate
Est. %3
Function
Origin
Polymethyl MethacrylateA powdered ingredient with an impressive sensory profile that gives off a creamy, sometimes velvety feeling on the skin. It is made up of tiny microspheres that roll smoothly across the skin and create slip and high spreadability.
PEG-40 Hydrogenated Castor Oil
Est. %2
Function
Origin
PEG-40 Hydrogenated Castor OilA castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
Ammonium Polyacryloyldimethyl Taurate
Est. %1.5
Function
Origin
Ammonium Polyacryloyldimethyl TaurateAn emulsion stabilizer and thickener with gelling properties. The products containing this ingredient frequently feature lightweight and refreshing aesthetics upon application to the skin.
Alcohol
Est. %1.3
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
Ascorbyl Glucoside
Est. %1
Function
Origin
Ascorbyl GlucosideA derivative of vitamin C. It is more stable and less irritating than ascorbic acid. There are unfortunately no clinical studies on ascorbyl glucoside’s anti-pigment or anti-acne efficacy alone.
Benzoic Acid
Est. %0.3
Function
Origin
Benzoic AcidA preservative effective against fungi, yeast, and some bacteria. It is commonly paired with phenoxyethanol to create a broad spectrum preservation system. Benzoic acid can also serve as a pH adjuster, fragrance, and bulking agent.
Bis-PEG-18 Methyl Ether Dimethyl Silane
Est. %0.3
Function
Origin
Bis-PEG-18 Methyl Ether Dimethyl SilaneA silicone with the unusual trait of being able to disperse in water. It moisturizes the skin as a humectant and leaves a soft and smooth after-feel. This ingredient also has foam-boosting properties.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Caesalpinia Spinosa Fruit Extract
Est. %0.3
Function
Origin
Caesalpinia Spinosa Fruit ExtractA powerful astringent ingredient extracted from Tara seed pods. It also has antioxidant benefits.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Yellow 6 (CI 15985)
Est. %0.3
Function
Origin
Yellow 6 (CI 15985)A petroleum-derived reddish-yellow dye, also known as Sunset Yellow. It is the third most used pigment in food, cosmetics, and drugs.
Citral
Est. %0.15
Function
Origin
Citral

A fragrant compound found in many essential oils (especially lemon myrtle and lemongrass essential oil). It has a sweet, lemon-like scent. People with sensitive skin should try to avoid products with citral, or at least do a patch test before using.

Citronellyl Methylcrotonate
Est. %0.3
Function
Origin
Citronellyl Methylcrotonate
Limonene
Est. %0.3
Function
Origin
Limonene

One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.

Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Hydrochloric Acid
Est. %0.3
Function
Origin
Hydrochloric Acid
Kappaphycus Alvarezii Extract
Est. %0.3
Function
Origin
Kappaphycus Alvarezii ExtractAn emollient extract obtained from the red marine algae called elkhorn sea moss. It is a good source of moisturizing and antioxidant carrageenan, a seaweed polysaccharide.
Linalool
Est. %0.3
Function
Origin
LinaloolA fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Magnesium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Magnesium Ascorbyl PhosphateOne of the best-researched derivatives of vitamin C. It is more resistant to light and air and retains all the properties of ascorbic acid – antioxidant, collagen-boosting, and anti-pigmentation, but with less irritation.
Methylsilanol Mannuronate
Est. %0.3
Function
Origin
Methylsilanol Mannuronate
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Propylene Glycol
Est. %0.3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Sodium Ascorbate
Est. %0.3
Function
Origin
Sodium AscorbateA well-researched sodium salt of vitamin C. It has antioxidant, collagen-boosting, and pigment-improving properties. It degrades very easily when exposed to air and needs careful packaging.
Sodium Chloride
Est. %0.3
Function
Origin
Sodium Chloride

You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions.

Sodium Cholate
Est. %0.3
Function
Origin
Sodium Cholate
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Soluble Proteoglycan
Est. %0.3
Function
Origin
Soluble Proteoglycan
Sorbic Acid
Est. %0.3
Function
Origin
Sorbic AcidAn organic acid that can be naturally found in the berries of the Mountain ash, although it is manufactured synthetically for skincare purposes. It is used as a preservative and antimicrobial agent, protecting a skincare product from spoiling.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Triethyl Citrate
Est. %0.3
Function
Origin
Triethyl Citrate
Trisodium Ascorbyl Palmitate Phosphate
Est. %0.3
Function
Origin
Trisodium Ascorbyl Palmitate Phosphate
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.