Paula's Choice Peptide Booster

Paula's Choice Peptide Booster
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle

Review

Does Paula's Choice Peptide Booster work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Paula's Choice Peptide Booster:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
  • Little anti-wrinkle effect: Paula's Choice Peptide Booster has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, Paula's Choice Peptide Booster is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Little anti-wrinkle efficacy

According to CreamScan analysis, Paula's Choice Peptide Booster has a minimal anti-wrinkle rating of 0.4 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Ectoin (est. ≈0.3%), 
 an amino acid-derived ingredient with moderate but proven anti-wrinkle efficacy.  A single clinical study involving 104 participants (Heinrich et al.) confirmed that a cream containing 2% ectoin reduced the average wrinkle width by 7% after 4 weeks of use, compared to the same formulation without ectoin (vehicle).
 
Among others, Paula's Choice Peptide Booster also contains some ingredients often marketed as effective in reducing wrinkles, specifically Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, and Adenosine. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
PEG-8 Dimethicone
Function:
Origin:
Tripeptide-1
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Palmitoyl Hexapeptide-12
Function:
Origin:
Myristoyl Hexapeptide-16
Function:
Origin:
Myristoyl Pentapeptide-17
Function:
Origin:
Hexanoyl Dipeptide-3 Norleucine Acetate
Function:
Origin:
Azelaoyl Bis-Dipeptide-10
Function:
Origin:
Glycoproteins
Function:
Origin:
Phospholipids
Function:
Origin:
Adenosine
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Arginine
Function:
Origin:
Valine
Function:
Origin:
Glycine
Function:
Origin:
Alanine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Serine
Function:
Origin:
Threonine
Function:
Origin:
Yeast Extract
Function:
Origin:
Isoleucine
Function:
Origin:
Proline
Function:
Origin:
Histidine
Function:
Origin:
Phenylalanine
Function:
Origin:
PCA
Function:
Origin:
Phytic Acid
Function:
Origin:
Panax Ginseng Root Extract
Function:
Origin:
Sodium PCA
Function:
Origin:
Psidium Guajava Fruit Extract
Function:
Origin:
Euterpe Oleracea Fruit Extract
Function:
Origin:
Ahnfeltiopsis Concinna Extract
Function:
Origin:
Dextran
Function:
Origin:
Hydrolyzed Silk
Function:
Origin:
Lecithin
Function:
Origin:
Glyceryl Polymethacrylate
Function:
Origin:
C12-16 Pareth-9
Function:
Origin:
Trideceth-12
Function:
Origin:
Sodium Lactate
Function:
Origin:
Carbomer
Function:
Origin:
Aspartic Acid
Function:
Origin:
Polysorbate 20
Function:
Origin:
Butylene Glycol
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
PEG-8
Function:
Origin:
C11-15 Pareth-7
Function:
Origin:
Guar Hydroxypropyltrimonium Chloride
Function:
Origin:
Phytosteryl/Octyldodecyl Lauroyl Glutamate
Function:
Origin:
Ectoin
Function:
Origin:
Citrate Buffer
Function:
Origin:
Trimethylsiloxyamodimethicone
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:

Ratings

All humectants
12.3
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.3 10
10.0
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 12.3 10
10
All humectants
12.3
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 2 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.4
Ectoin
0.4
Ingredient anti-wrinkle power
2.5 /10
when present at, %
2
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Hexapeptide-12
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
All antioxidants 1.5 3 No
All antioxidants
1.5
Palmitoyl Hexapeptide-12
0.3
Glycoproteins
0.3
Panax Ginseng Root Extract
0.3
Psidium Guajava Fruit Extract
0.3
Euterpe Oleracea Fruit Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
All soothing 1.2 5 No
All soothing
1.2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

PEG-8 Dimethicone
Est. %4
Function
Origin
PEG-8 Dimethicone
Tripeptide-1
Est. %0.3
Function
Origin
Tripeptide-1

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Palmitoyl Hexapeptide-12
Est. %0.3
Function
Origin
Palmitoyl Hexapeptide-12

A short, synthetically made peptide similar to elastin fragments. It works as a signal peptide, stimulating the growth of skin cells and facilitating skin repair. It has been tested mostly in test-tube experiments so far.

Myristoyl Hexapeptide-16
Est. %0.3
Function
Origin
Myristoyl Hexapeptide-16
Myristoyl Pentapeptide-17
Est. %0.3
Function
Origin
Myristoyl Pentapeptide-17
Hexanoyl Dipeptide-3 Norleucine Acetate
Est. %0.3
Function
Origin
Hexanoyl Dipeptide-3 Norleucine Acetate
Azelaoyl Bis-Dipeptide-10
Est. %0.3
Function
Origin
Azelaoyl Bis-Dipeptide-10
Glycoproteins
Est. %0.3
Function
Origin
GlycoproteinsA broad term indicating a specific type of proteins, most likely of animal origin.
Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Valine
Est. %0.3
Function
Origin
ValineAn essential amino acid (meaning our body cannot make it on its own and we get it from food instead). Like some other amino acids, Valine is a part of the skin's Natural Moisturizing Factor.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Threonine
Est. %0.3
Function
Origin
ThreonineAn essential amino acid that may play a role in collagen production. However, more research is needed in order to confirm or deny these claims.
Yeast Extract
Est. %0.3
Function
Origin
Yeast ExtractAlso labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
Isoleucine
Est. %0.3
Function
Origin
IsoleucineA humectant moisturizing, essential amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to increase water content on the skin’s surface and can increase the barrier repair effects of ceramides.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Histidine
Est. %0.3
Function
Origin
HistidineA humectant moisturizing amino acid with weak antioxidant effects that is a part of the skin’s Natural Moisturizing Factor. It can attract water to the skin’s surface and is slightly alkaline, thereby helping to balance a product's pH.
Phenylalanine
Est. %0.3
Function
Origin
PhenylalanineAn essential amino acid used in the treatment of vitiligo and other pigmentation issues. It is considered less effective than other anti-pigment ingredients and is often used in combination with them.
PCA
Est. %0.3
Function
Origin
PCAAlso known as pyrrolidone carboxylic acid, this ingredient is one of the main components of the skin's Natural Moisturizing Factor (which prevents the skin’s surface from drying out).
Phytic Acid
Est. %0.3
Function
Origin
Phytic AcidPhytic acid is found in rice and is seen as a cousin of alpha-hydroxy acids. As a chelator, it can bind to certain metals that may cause discoloration in products or reduce the efficacy of other ingredients.
Panax Ginseng Root Extract
Est. %0.3
Function
Origin
Panax Ginseng Root ExtractDerived from the roots of the Korean Ginseng, this extract contains a mixture of antioxidant and soothing ginsenosides which are proven to reduce inflammation and treat eczema. The root is a major part of Chinese traditional medicine.
Sodium PCA
Est. %0.3
Function
Origin
Sodium PCAOne of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Psidium Guajava Fruit Extract
Est. %0.3
Function
Origin
Psidium Guajava Fruit ExtractAn extract obtained from guava fruit of South America with astringent and antioxidant phenolic compounds.
Euterpe Oleracea Fruit Extract
Est. %0.3
Function
Origin
Euterpe Oleracea Fruit ExtractAn antioxidant extract obtained from the fruits of the acai palm. It has a high content of anthocyanins, responsible for the dark purple color, as well as other antioxidant phenolic compounds.
Ahnfeltiopsis Concinna Extract
Est. %0.3
Function
Origin
Ahnfeltiopsis Concinna Extract
Dextran
Est. %0.3
Function
Origin
DextranA naturally derived sucrose metabolite that thickens water and bulks emulsions.
Hydrolyzed Silk
Est. %0.3
Function
Origin
Hydrolyzed SilkA moisturizing ingredient obtained from natural silk. Some studies have shown that hydrolyzed skin proteins have anti-inflammatory properties.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Glyceryl Polymethacrylate
Est. %0.3
Function
Origin
Glyceryl PolymethacrylateA synthetic polymer that is typically used as a viscosity modifier. Its benefits include a light after-feel on the skin and soft film, which is why it is frequently used in serums. It can form transparent gels and suspend some oils and particulates.
C12-16 Pareth-9
Est. %0.3
Function
Origin
C12-16 Pareth-9
Trideceth-12
Est. %0.3
Function
Origin
Trideceth-12
Sodium Lactate
Est. %0.3
Function
Origin
Sodium LactateA sodium salt of lactic acid. Its main function is as a humectant but it can also serve as a pH adjuster. Additionally, sodium lactate can also be used as a chemical exfoliant due to its close chemical relation to lactic acid.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Aspartic Acid
Est. %0.3
Function
Origin
Aspartic AcidA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to retain water on the skin’s surface and is slightly acidic, thereby helping to balance the pH of a skincare product.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
PEG-8
Est. %0.3
Function
Origin
PEG-8A synthetic liquid that serves as a humectant. It also works as a solvent because of its ability to dissolve a wide range of ingredients.
C11-15 Pareth-7
Est. %0.3
Function
Origin
C11-15 Pareth-7
Guar Hydroxypropyltrimonium Chloride
Est. %0.3
Function
Origin
Guar Hydroxypropyltrimonium Chloride
Phytosteryl/Octyldodecyl Lauroyl Glutamate
Est. %0.3
Function
Origin
Phytosteryl/Octyldodecyl Lauroyl GlutamateAn emollient ingredient that is similar to ceramides in its structure. It provides a smooth and soft feeling to the skin.
Ectoin
Est. %0.3
Function
Origin
Ectoin

An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.

Citrate Buffer
Est. %0.3
Function
Origin
Citrate Buffer
Trimethylsiloxyamodimethicone
Est. %0.3
Function
Origin
Trimethylsiloxyamodimethicone
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.