Numbuzin No.5 Vitamin Concentrated Serum

Numbuzin No.5 Vitamin Concentrated Serum
5.4
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.8 Occlusivity icon Occlusivity
6.1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Does Numbuzin No.5 Vitamin Concentrated Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Numbuzin No.5 Vitamin Concentrated Serum:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.4 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.1 out of 10, Numbuzin No.5 Vitamin Concentrated Serum is effective in minimizing wrinkles.
  • Soothing: Numbuzin No.5 Vitamin Concentrated Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, Numbuzin No.5 Vitamin Concentrated Serum is quite moisturizing, with a moisturizing rating of 5.4 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.8 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Niacinamide (est. ≈4.0%) and Panthenol (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Significant anti-wrinkle efficacy

According to CreamScan analysis, Numbuzin No.5 Vitamin Concentrated Serum has a high anti-wrinkle rating of 6.1 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈4.0%),
     one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
  • Ascorbic Acid (est. ≈0.3%),
     or Vitamin C, a popular ingredient, yet with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 20 participants (Humbert et al.). This study showed that a cream with a relatively high concentration of 5% ascorbic acid reduced the average wrinkle depth by 7% after 6 months of use, compared to a vehicle (the same formulation without ascorbic acid).
Among others, Numbuzin No.5 Vitamin Concentrated Serum also contains some ingredients often marketed as effective in reducing wrinkles, specifically Melia Azadirachta Leaf Extract, 3-O-Ethyl Ascorbic Acid, Adenosine, Beta-Glucan, Ascorbyl Glucoside, and Ubiquinone. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Numbuzin No.5 Vitamin Concentrated Serum is rich (> 3%) in antioxidants, specifically Vaccinium Vitis-Idaea Fruit Extract (est. ≈70.0%) and Niacinamide (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing and calming potential

Based on the ingredient list analysis, Numbuzin No.5 Vitamin Concentrated Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈4.0%) and Panthenol (est. ≈3.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Vaccinium Vitis-Idaea Fruit Extract
Function:
Origin:
Butylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
Panthenol
Function:
Origin:
Water
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Neopentyl Glycol Dicaprate
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Sorbitol
Function:
Origin:
Bifida Ferment Lysate
Function:
Origin:
Chondrus Crispus Extract
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Saccharum Officinarum (Sugarcane) Extract
Function:
Origin:
Alpha-Arbutin
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Melia Azadirachta Flower Extract
Function:
Origin:
Ocimum Sanctum Leaf Extract
Function:
Origin:
Melia Azadirachta Leaf Extract
Function:
Origin:
Curcuma Longa (Turmeric) Root Extract
Function:
Origin:
Corallina Officinalis Extract
Function:
Origin:
Tremella Fuciformis (Mushroom) Extract
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
3-O-Ethyl Ascorbic Acid
Function:
Origin:
Bisabolol
Function:
Origin:
Tromethamine
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Adenosine
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Allantoin
Function:
Origin:
Glutathione
Function:
Origin:
Ceramide NP
Function:
Origin:
Beta-Glucan
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Tocopherol
Function:
Origin:
Ascorbic Acid
Function:
Origin:
Ascorbyl Glucoside
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Hydroxypropyl Cyclodextrin
Function:
Origin:
Ubiquinone
Function:
Origin:
Thioctic Acid
Function:
Origin:
Potassium Hydroxide
Function:
Origin:
Behenyl Alcohol
Function:
Origin:
Carbomer
Function:
Origin:
Xanthan Gum
Function:
Origin:
Disodium EDTA
Function:
Origin:

Ratings

All humectants
16.3
6
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.6
1.0
0.3
0.3
Benchmark
20
Moisturizing rating
5.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 16.3 10
10.0
6
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.6 20
0.8
1.0
0.3
0.3
Moisturizing rating
5.4
Ingredient Est. % Benchmark Humectancy
6
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 16.3 10
10
All humectants
16.3
6
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1
0.3
0.3
All occlusives 1.6 20
0.8
All occlusives
1.6
1.0
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
2.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
6.1
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
3-O-Ethyl Ascorbic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ascorbyl Glucoside
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6.1
Ingredient Est. % Benchmark
Rich in Antioxidants
70
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 79.1 3 Rich in antioxidants
All antioxidants
79.1
Vaccinium Vitis-Idaea Fruit Extract
70
Niacinamide
4
Ascorbic Acid
0.3
Saccharum Officinarum (Sugarcane) Extract
0.3
Alpha-Arbutin
0.3
Sodium Hyaluronate
0.3
Melia Azadirachta Flower Extract
0.3
Ocimum Sanctum Leaf Extract
0.3
Melia Azadirachta Leaf Extract
0.3
Curcuma Longa (Turmeric) Root Extract
0.3
Corallina Officinalis Extract
0.3
3-O-Ethyl Ascorbic Acid
0.3
Glutathione
0.3
Beta-Glucan
0.3
Tocopherol
0.3
Ascorbyl Glucoside
0.3
Tocopheryl Acetate
0.3
Ubiquinone
0.3
Thioctic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 9.4 5 Rich in soothing
All soothing
9.4
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Vaccinium Vitis-Idaea Fruit Extract
Est. %70
Function
Origin
Vaccinium Vitis-Idaea Fruit Extract
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Niacinamide
Est. %4
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Panthenol
Est. %3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Water
Est. %2
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
1,2-Hexanediol
Est. %1.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Neopentyl Glycol Dicaprate
Est. %1.3
Function
Origin
Neopentyl Glycol Dicaprate
Caprylic/Capric Triglyceride
Est. %1
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Sorbitol
Est. %0.3
Function
Origin
SorbitolA sweet-tasting alcohol derived from glucose. Aside from its sweet taste (for which it is used as a very common sweetener), Sorbitol is also very good at retaining water and is used in skincare as a humectant.
Bifida Ferment Lysate
Est. %0.3
Function
Origin
Bifida Ferment LysateA mixture of probiotic bacteria. According to the patent holder, it contains enzymes that are able to repair damaged DNA in skin cells. A single study confirms that it is able to reduce skin sensitivity.
Chondrus Crispus Extract
Est. %0.3
Function
Origin
Chondrus Crispus ExtractAn extract from the species of red marine algae called Irish moss or carrageen moss. It is edible and widely used to produce carrageenan, a polysaccharide with humectant moisturizing and soothing properties.
Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Saccharum Officinarum (Sugarcane) Extract
Est. %0.3
Function
Origin
Saccharum Officinarum (Sugarcane) ExtractAn antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Alpha-Arbutin
Est. %0.3
Function
Origin
Alpha-Arbutin
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Melia Azadirachta Flower Extract
Est. %0.3
Function
Origin
Melia Azadirachta Flower ExtractAn antioxidant extract derived from the flowers of the Indian lilac, also known as Neem. It is often used in traditional medicine in India. The Neem flower extracts contain limonoids, which are currently under research for their anti-pigment activity.
Ocimum Sanctum Leaf Extract
Est. %0.3
Function
Origin
Ocimum Sanctum Leaf ExtractAn extract derived from the leaves of Holy Basil, also known as Tulsi, a traditional herb used in Ayurveda medicine. It contains antioxidant and anti-inflammatory rosmarinic acid, galic acid, flavonoids, and a sweet-scented essential oil.
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
Melia Azadirachta Leaf ExtractAn antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Curcuma Longa (Turmeric) Root Extract
Est. %0.3
Function
Origin
Curcuma Longa (Turmeric) Root ExtractAn extract derived from the thick roots of curcuma (turmeric), a famous yellow spice and a major ingredient in curry powder. It is used in skincare for its proven antioxidant and anti-inflammatory properties.
Corallina Officinalis Extract
Est. %0.3
Function
Origin
Corallina Officinalis ExtractAn extract from red marine alga, Corallina officinalis is used in skincare for its antioxidant properties. It also contains an immense amount of calcium and special, sulfur-containing polysaccharides.
Tremella Fuciformis (Mushroom) Extract
Est. %0.3
Function
Origin
Tremella Fuciformis (Mushroom) ExtractAn extract derived from an edible mushroom known as snow fungus. It is full of various proteins, fiber, and humectant moisturizing polysaccharides.
Pentylene Glycol
Est. %0.3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Glycerin
Est. %0.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

3-O-Ethyl Ascorbic Acid
Est. %0.3
Function
Origin
3-O-Ethyl Ascorbic AcidA derivative of vitamin C. Its stability in skincare formulations is better than ascorbic acid’s, although clinical studies are yet to indicate whether it has the same collagen-boosting benefits.
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Ascorbic Acid
Est. %0.3
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Ascorbyl Glucoside
Est. %0.3
Function
Origin
Ascorbyl GlucosideA derivative of vitamin C. It is more stable and less irritating than ascorbic acid. There are unfortunately no clinical studies on ascorbyl glucoside’s anti-pigment or anti-acne efficacy alone.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Hydroxypropyl Cyclodextrin
Est. %0.3
Function
Origin
Hydroxypropyl CyclodextrinA white crystalline powder that can reduce odors coming from other ingredients in a product.
Ubiquinone
Est. %0.3
Function
Origin
UbiquinoneAlso known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Thioctic Acid
Est. %0.3
Function
Origin
Thioctic Acid
Potassium Hydroxide
Est. %0.3
Function
Origin
Potassium HydroxideA very alkaline ingredient, meaning that it has a high pH. Potassium hydroxide is therefore useful in bringing a low pH in a cosmetic product up to a more neutral, skin-safe level.
Behenyl Alcohol
Est. %0.3
Function
Origin
Behenyl AlcoholA fatty alcohol with emollient properties. It is used as a co-emulsifier and thickener and tends to result in a product with a smooth and creamy application texture.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.