Numbuzin No. 5 Goodbye Blemish Serum

Numbuzin No. 5 Goodbye Blemish Serum
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
2.1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Does Numbuzin No. 5 Goodbye Blemish Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Numbuzin No. 5 Goodbye Blemish Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.1 out of 10.
  • Some anti-wrinkle efficacy: Numbuzin No. 5 Goodbye Blemish Serum has an anti-wrinkle rating of 2.1 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Soothing: Numbuzin No. 5 Goodbye Blemish Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Numbuzin No. 5 Goodbye Blemish Serum has a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Methyl Gluceth-20 (est. ≈4.0%) and Glycerin (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Numbuzin No. 5 Goodbye Blemish Serum has a slight anti-wrinkle rating of 2.1 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈1.3%),
     one of the most effective and well-researched anti-wrinkle ingredients.
  • Ascorbic Acid (est. ≈0.3%),
     or Vitamin C, a popular anti-wrinkle ingredient, yet with average efficacy confirmed by only one study.
Among others, Numbuzin No. 5 Goodbye Blemish Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Melia Azadirachta Leaf Extract, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Ascorbyl Glucoside, and 3-O-Ethyl Ascorbic Acid. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Numbuzin No. 5 Goodbye Blemish Serum is rich (> 3%) in antioxidants, specifically Hippophae Rhamnoides Extract (est. ≈70.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Numbuzin No. 5 Goodbye Blemish Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈1.3%), Ocimum Sanctum Leaf Extract (est. ≈0.3%), Melia Azadirachta Leaf Extract (est. ≈0.3%), and others.

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.15
0.3
Est. %
Hippophae Rhamnoides Extract
Function:
Origin:
Butylene Glycol
Function:
Origin:
Methyl Gluceth-20
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Niacinamide
Function:
Origin:
Melia Azadirachta Flower Extract
Function:
Origin:
Ocimum Sanctum Leaf Extract
Function:
Origin:
Melia Azadirachta Leaf Extract
Function:
Origin:
Curcuma Longa (Turmeric) Root Extract
Function:
Origin:
Corallina Officinalis Extract
Function:
Origin:
Citrus Limon (Lemon) Peel Oil
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Peel Oil
Function:
Origin:
Citrus Aurantifolia (Lime) Oil
Function:
Origin:
Polygonum Cuspidatum Root Extract
Function:
Origin:
Scutellaria Baicalensis Root Extract
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Extract
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Rosmarinus Officinalis (Rosemary) Leaf Extract
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Ascorbyl Glucoside
Function:
Origin:
Ascorbic Acid
Function:
Origin:
3-O-Ethyl Ascorbic Acid
Function:
Origin:
Panthenol
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Glycereth-26
Function:
Origin:
Ammonium Acryloyldimethyltaurate/VP Copolymer
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Carbomer
Function:
Origin:
Allantoin
Function:
Origin:
Tromethamine
Function:
Origin:
Water
Function:
Origin:
Hydrolyzed Jojoba Esters
Function:
Origin:
Disodium EDTA
Function:
Origin:
Citral
Function:
Origin:
Limonene
Function:
Origin:

Ratings

All humectants
15.7
6
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 15.7 10
10.0
6
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 15.7 10
10
All humectants
15.7
6
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1.3 2
2.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.1
Niacinamide
2
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1.3
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ascorbyl Glucoside
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
3-O-Ethyl Ascorbic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.1
Ingredient Est. % Benchmark
Rich in Antioxidants
70
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 76.8 3 Rich in antioxidants
All antioxidants
76.8
Hippophae Rhamnoides Extract
70
Niacinamide
1.3
Melia Azadirachta Flower Extract
1
Ascorbic Acid
0.3
Ocimum Sanctum Leaf Extract
0.3
Melia Azadirachta Leaf Extract
0.3
Curcuma Longa (Turmeric) Root Extract
0.3
Corallina Officinalis Extract
0.3
Polygonum Cuspidatum Root Extract
0.3
Scutellaria Baicalensis Root Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Chamomilla Recutita (Matricaria) Flower Extract
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Centella Asiatica Extract
0.3
Ascorbyl Glucoside
0.3
3-O-Ethyl Ascorbic Acid
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 5.2 5 Rich in soothing
All soothing
5.2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Hippophae Rhamnoides Extract
Est. %70
Function
Origin
Hippophae Rhamnoides ExtractAn extract from sea buckthorn fruits. It contains various antioxidant and astringent compounds and significantly improved skin elasticity in a small clinical study.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Methyl Gluceth-20
Est. %4
Function
Origin
Methyl Gluceth-20A humectant synthetically derived from glucose. It takes on the form of a clear, syrupy liquid.
Dipropylene Glycol
Est. %3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Glycerin
Est. %2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

1,2-Hexanediol
Est. %1.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Niacinamide
Est. %1.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Melia Azadirachta Flower Extract
Est. %1
Function
Origin
Melia Azadirachta Flower ExtractAn antioxidant extract derived from the flowers of the Indian lilac, also known as Neem. It is often used in traditional medicine in India. The Neem flower extracts contain limonoids, which are currently under research for their anti-pigment activity.
Ocimum Sanctum Leaf Extract
Est. %0.3
Function
Origin
Ocimum Sanctum Leaf ExtractAn extract derived from the leaves of Holy Basil, also known as Tulsi, a traditional herb used in Ayurveda medicine. It contains antioxidant and anti-inflammatory rosmarinic acid, galic acid, flavonoids, and a sweet-scented essential oil.
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
Melia Azadirachta Leaf ExtractAn antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Curcuma Longa (Turmeric) Root Extract
Est. %0.3
Function
Origin
Curcuma Longa (Turmeric) Root ExtractAn extract derived from the thick roots of curcuma (turmeric), a famous yellow spice and a major ingredient in curry powder. It is used in skincare for its proven antioxidant and anti-inflammatory properties.
Corallina Officinalis Extract
Est. %0.3
Function
Origin
Corallina Officinalis ExtractAn extract from red marine alga, Corallina officinalis is used in skincare for its antioxidant properties. It also contains an immense amount of calcium and special, sulfur-containing polysaccharides.
Citrus Limon (Lemon) Peel Oil
Est. %0.3
Function
Origin
Citrus Limon (Lemon) Peel Oil

A fragrant essential oil extracted from the rind or peel of a lemon. It is mainly comprised of limonene (up to 70%) and has a fresh, citrusy scent. Lemon peel oil may cause a sun-induced skin rash in people with a sensitivity towards citrus fruits.

Citrus Aurantium Dulcis (Orange) Peel Oil
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Peel Oil

An essential oil derived from the peels of the sweet orange. It is commonly used as a fragrance because of its pleasant, citrusy scent. The main constituent of the essential oil is limonene (up to 96%).

Citrus Aurantifolia (Lime) Oil
Est. %0.3
Function
Origin
Citrus Aurantifolia (Lime) Oil

A fragrant essential oil extracted from lime peels that is mostly comprised of limonene, pinene, terpinene, and terpineol - which give off a sweet citrusy scent.

Polygonum Cuspidatum Root Extract
Est. %0.3
Function
Origin
Polygonum Cuspidatum Root ExtractAn extract from the roots of the Japanese knotweed, a plant from East Asia that has spread around the world as an invasive plant. It contains various antioxidant, anti-inflammatory, and potentially anti-pigment (more tests are necessary) phytochemicals.
Scutellaria Baicalensis Root Extract
Est. %0.3
Function
Origin
Scutellaria Baicalensis Root ExtractA powerful antioxidant, soothing, and astringent extract derived from the roots of Baikal/Chinese skullcap. It contains various unique flavonoids that are believed to soothe irritated and inflamed skin and protect from UV-induced oxidative damage.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
Camellia Sinensis Leaf Extract

An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.

Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root ExtractAn extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Chamomilla Recutita (Matricaria) Flower Extract
Est. %0.3
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
Rosmarinus Officinalis (Rosemary) Leaf ExtractA soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Ascorbyl Glucoside
Est. %0.3
Function
Origin
Ascorbyl GlucosideA derivative of vitamin C. It is more stable and less irritating than ascorbic acid. There are unfortunately no clinical studies on ascorbyl glucoside’s anti-pigment or anti-acne efficacy alone.
Ascorbic Acid
Est. %0.3
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

3-O-Ethyl Ascorbic Acid
Est. %0.3
Function
Origin
3-O-Ethyl Ascorbic AcidA derivative of vitamin C. Its stability in skincare formulations is better than ascorbic acid’s, although clinical studies are yet to indicate whether it has the same collagen-boosting benefits.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Glycereth-26
Est. %0.3
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %0.3
Function
Origin
Ammonium Acryloyldimethyltaurate/VP CopolymerA polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Water
Est. %0.3
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Hydrolyzed Jojoba Esters
Est. %0.3
Function
Origin
Hydrolyzed Jojoba EstersAn occlusive moisturizing mixture of fatty acids and fatty alcohols obtained from jojoba oil. It is also used as a formula helper.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Citral
Est. %0.15
Function
Origin
Citral

A fragrant compound found in many essential oils (especially lemon myrtle and lemongrass essential oil). It has a sweet, lemon-like scent. People with sensitive skin should try to avoid products with citral, or at least do a patch test before using.

Limonene
Est. %0.3
Function
Origin
Limonene

One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.