Natura Bisse Inhibit High Definition Serum

Natura Bisse Inhibit High Definition Serum
5.8
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.5 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
$$$$

Review

Results you may expect from using Natura Bisse Inhibit High Definition Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Natura Bisse Inhibit High Definition Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.8 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Natura Bisse Inhibit High Definition Serum is effective in minimizing wrinkles.
  • Soothing: Natura Bisse Inhibit High Definition Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Natura Bisse Inhibit High Definition Serum has a moisturizing rating of 5.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.5 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Niacinamide (est. ≈4.0%), Propanediol (est. ≈3.0%) and Betaine (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Natura Bisse Inhibit High Definition Serum has a high anti-wrinkle rating of 6.0 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈4.0%),
 one of the most effective and well-researched anti-wrinkle ingredients.
 
Among others, Natura Bisse Inhibit High Definition Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically sh-Oligopeptide-1, sh-Polypeptide-1, sh-Polypeptide-9, Acetyl Octapeptide-3, and Palmitoyl Tripeptide-38. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Natura Bisse Inhibit High Definition Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Natura Bisse Inhibit High Definition Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈4.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
60
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
14.5
4
3
2
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
3.0
1.5
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 14.5 10
10.0
4
3
2
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 3.0 20
1.5
1.5
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
5.8
Ingredient Est. % Benchmark Humectancy
4
3
2
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 14.5 10
10
All humectants
14.5
4
3
2
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.5
0.3
0.3
0.3
0.3
0.3
All occlusives 3.0 20
1.5
All occlusives
3.0
1.5
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
sh-Oligopeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
sh-Polypeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
sh-Polypeptide-9
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Octapeptide-3
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-38
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.7 3 Rich in antioxidants
All antioxidants
6.7
Niacinamide
4
Amaranthus Caudatus Seed Extract
0.3
Sodium Hyaluronate
0.3
Hydrolyzed Hyaluronic Acid
0.3
Hydrolyzed Sodium Hyaluronate
0.3
Bacillus/Folic Acid Ferment Filtrate Extract
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Tocopherol
0.3
Benzotriazolyl Dodecyl p-Cresol
0.3
Octadecyl Di-t-butyl-4-hydroxyhydrocinnamate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
1
0.3
All soothing 5.3 5 Rich in soothing
All soothing
5.3
4
1
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
C12-20 Acid PEG-8 Ester
Est. %6
Function
Origin
A powerful synthetic emulsifier that is very gentle to the skin.
Niacinamide
Est. %4
Function
Origin

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Propanediol
Est. %3
Function
Origin
An excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Betaine
Est. %2
Function
Origin
An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Pentaerythrityl Tetracaprylate/Tetracaprate
Est. %1.5
Function
Origin
Description is coming soon
Glyceryl Stearate
Est. %1.3
Function
Origin
An emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Panthenol
Est. %1
Function
Origin
A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Glycerin
Est. %0.3
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Cyclopentasiloxane
Est. %0.3
Function
Origin
A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
A semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Amaranthus Caudatus Seed Extract
Est. %0.3
Function
Origin
An extract from amaranth seeds. Depending on the extraction it can be either rich in humectant essential amino acids (namely lysine), proteins, and minerals or emollient and occlusive fatty acids.
Hydrolyzed Collagen
Est. %0.3
Function
Origin
A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.
Mangifera Indica (Mango) Seed Butter
Est. %0.3
Function
Origin
A fat obtained from the kernel of the mango seed. It is a semi-solid, plant-based butter that is used for consumption, and as an emollient and occlusive moisturizer in skincare.
Xylitylglucoside
Est. %0.3
Function
Origin
An emollient extract from rice bran, the brown outer part of the rice kernel. It includes palmitic, stearic, oleic, linoleic acids, and antioxidants such as tocopherols and γ-oryzanol.
Anhydroxylitol
Est. %0.3
Function
Origin
A derivative of xylitol, a naturally occurring sugar alcohol. It has humectant moisturizing properties.
C10-30 Cholesterol/Lanosterol Esters
Est. %0.3
Function
Origin
A mixture of lipids isolated from lanolin. They are similar to the lipids from the skin’s lipid barrier. It is a very good emollient and leaves a shiny and glossy finish on the skin.
Sorghum Bicolor Stalk Juice
Est. %0.3
Function
Origin
Description is coming soon
Xylitol
Est. %0.3
Function
Origin
An organic compound that is most well-known for its use as a sweetener that also protects your teeth from cavities. Xylitol is used in skincare as a moisturizing humectant and has been shown to improve the protective barrier function of the skin.
Acetyl Glutamine
Est. %0.3
Function
Origin
Description is coming soon
Arginine
Est. %0.3
Function
Origin
A humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Sodium Hyaluronate
Est. %0.3
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Hydrolyzed Sodium Hyaluronate
Est. %0.3
Function
Origin
A very small-molecule version of regular sodium hyaluronate. It is a powerful humectant skin-identical ingredient that absorbs into the skin and offers plumping, smoothing, and anti-wrinkle effects.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
A fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
sh-Oligopeptide-1
Est. %0.3
Function
Origin

Also known as Human Epidermal Growth Factor. It increases metabolism in skin cells and is claimed to improves skin texture and elasticity.

sh-Oligopeptide-2
Est. %0.3
Function
Origin

Description is coming soon

sh-Polypeptide-1
Est. %0.3
Function
Origin

Also known as Basic Fibroblast Growth Factor. It has collagen and elastin-boosting effects and can result in firmer, more elastic skin. It has been tested for scar healing, but its use in skincare products is still a bit controversial.

sh-Polypeptide-9
Est. %0.3
Function
Origin

Also known as Vascular Endothelial Growth Factor. It stimulates the formation of new blood vessels, thereby improving microcirculation. It is not well researched for use in skincare and is still a bit controversial.

sh-Polypeptide-11
Est. %0.3
Function
Origin
Description is coming soon
Bacillus/Folic Acid Ferment Filtrate Extract
Est. %0.3
Function
Origin

Combined with folic acid and derived from Bacillus fermentation, this extract acts as a humectant, retaining moisture to keep skin hydrated, and as an antioxidant, shielding skin from free-radical damage.

Acetyl Octapeptide-3
Est. %0.3
Function
Origin

A synthetically made peptide with an effect similar to Botox - it relaxes the facial muscles and temporarily reduces the appearance of mimic wrinkles.

s-Mu-conotoxin CnIIIC
Est. %0.3
Function
Origin
Description is coming soon
sh-Polypeptide-59
Est. %0.3
Function
Origin
Description is coming soon
Palmitoyl Tripeptide-38
Est. %0.3
Function
Origin

A small synthetic peptide that increases the production of collagen, fibronectin, and hyaluronic acid in the skin. It has also been shown to reduce wrinkles in combination with other anti-aging ingredients.

Copper Heptapeptide-14 Pantothenate
Est. %0.3
Function
Origin
Description is coming soon
Heptapeptide-15 Palmitate
Est. %0.3
Function
Origin
Description is coming soon
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
A soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Tocopherol
Est. %0.3
Function
Origin
Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.
Sodium Polystyrene Sulfonate
Est. %0.3
Function
Origin
Description is coming soon
Dimethicone
Est. %0.3
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Cetyl Phosphate
Est. %0.3
Function
Origin
Description is coming soon
Dimethiconol
Est. %0.3
Function
Origin
A synthetic dimethicone with rich, non-tacky emolliency. It features the typical sensorial profile of silicones, with high spreadability and a luxurious, oil-free after-feel. Dimethiconol can also serve as an antifoaming agent.
Sodium Acrylates Copolymer
Est. %0.3
Function
Origin
A synthetic polymer that can come in various forms and is often used to create light gel-like textures. Some versions can also create a light film on the skin.
Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Hydrogenated Polyisobutene
Est. %0.3
Function
Origin
A viscous liquid that makes a great oil base due to its smooth sensorial profile. It has emollient features, including good spreadability and little tack upon application. It also has the added benefit of being able to thicken products.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
A synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Benzotriazolyl Dodecyl p-Cresol
Est. %0.3
Function
Origin
Description is coming soon
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Octadecyl Di-t-butyl-4-hydroxyhydrocinnamate
Est. %0.3
Function
Origin
Description is coming soon
Phospholipids
Est. %0.3
Function
Origin
A large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Polyglyceryl-10 Stearate
Est. %0.3
Function
Origin
A naturally-derived or synthetically produced mild emulsifier.
Decylene Glycol
Est. %0.3
Function
Origin
Description is coming soon
Silica
Est. %0.3
Function
Origin
A widely used cosmetic ingredient with the same chemical composition as the sand found on beaches. A common function of silica is its ability to control viscosity. In certain chemical forms, it can effectively thicken cream-style products.
Hydroxypropyl Cyclodextrin
Est. %0.3
Function
Origin
A white crystalline powder that can reduce odors coming from other ingredients in a product.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
1,2-Hexanediol
Est. %0.3
Function
Origin
A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Glyceryl Caprylate
Est. %0.3
Function
Origin
A waxy solid derived from vegetable oils that has emollient and emulsifying properties. It is also known to boost the efficacy of organic acid preservatives by destabilizing the microbe's cell membrane.
Polyvinyl Alcohol
Est. %0.3
Function
Origin
A synthetic polymer that thickens water to form a gel and prevents other ingredients from separating.
Lactic Acid/Glycolic Acid Copolymer
Est. %0.3
Function
Origin
Description is coming soon
Octoxynol-9
Est. %0.3
Function
Origin
Description is coming soon
Dextran
Est. %0.3
Function
Origin
A naturally derived sucrose metabolite that thickens water and bulks emulsions.
Polysorbate 20
Est. %0.3
Function
Origin
A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Potassium Sorbate
Est. %0.3
Function
Origin
A preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Sodium Benzoate
Est. %0.3
Function
Origin
A preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Limonene
Est. %0.3
Function
Origin
One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.
Geraniol
Est. %0.3
Function
Origin
A fragrant, volatile, plant-based, liquid chemical that can be naturally found in many essential oils (specifically rose, palmarosa, citronella). It has a rose-like scent. It is a potential irritant and may cause an allergic reaction in some people.
Hydroxycitronellal
Est. %0.3
Function
Origin
A fragrant compound with a scent reminiscent of lilies and sweet tropical melon. It can be found in many different essential oils (such as palmarosa, ylang-ylang, and lemongrass essential oil) but is manufactured synthetically from citronellal.
Linalool
Est. %0.3
Function
Origin
A fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Citronellol
Est. %0.3
Function
Origin
A fragrant compound found naturally in many essential oils (mainly lemongrass). It can have a lemon or a rose scent. People with sensitive skin should try to avoid products with citronellol, or at least do a patch test before using it.
Cinnamyl Alcohol
Est. %0.3
Function
Origin
A naturally-found or synthetically produced component of fragrances. It smells sweet, spicy, and cinnamon-like. It is a known fragrance allergen, but not expected to be irritating when used below recommended limits.
Citral
Est. %0.3
Function
Origin
A fragrant compound found in many essential oils (especially lemon myrtle and lemongrass essential oil). It has a sweet, lemon-like scent. People with sensitive skin should try to avoid products with citral, or at least do a patch test before using.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Mica
Est. %0.3
Function
Origin
A mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Caramel
Est. %0.3
Function
Origin
A natural ingredient that is derived from the heat treatment of table sugar. Caramel is used in skincare as a natural colorant that can create transparent, dark brown solutions. It also works as a fragrance, where it provides a sweet, sugary scent.
Yellow 5 (CI 19140)
Est. %0.3
Function
Origin
A bright yellow colorant that is often also listed as FD&C Yellow 5.