Make p:rem Poncirus Trifoliata C Dark Spot Serum

Make p:rem Poncirus Trifoliata C Dark Spot Serum
5.3
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
3.6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does Make p:rem Poncirus Trifoliata C Dark Spot Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Make p:rem Poncirus Trifoliata C Dark Spot Serum:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.3 out of 10.
  • Some anti-wrinkle efficacy: Make p:rem Poncirus Trifoliata C Dark Spot Serum has an anti-wrinkle rating of 3.6 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, Make p:rem Poncirus Trifoliata C Dark Spot Serum is quite moisturizing, with a moisturizing rating of 5.3 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Propanediol (est. ≈6.0%), Glycerin (est. ≈4.0%) and Niacinamide (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, Make p:rem Poncirus Trifoliata C Dark Spot Serum has a slight anti-wrinkle rating of 3.6 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈2.0%),
     one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
  • Ascorbyl Tetraisopalmitate (est. ≈0.3%),
     the only derivative of ascorbic acid with solid evidence of anti-wrinkle efficacy. A single clinical study involving 23 participants (Mariko et al.) demonstrated that a cream with 1% ATIP reduced the average depth of periorbital wrinkles by 6% after 8 weeks of use, compared to a vehicle (the same formulation without ATIP).
Among others, Make p:rem Poncirus Trifoliata C Dark Spot Serum also contains contains Melia Azadirachta Leaf Extract and Adenosine, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Make p:rem Poncirus Trifoliata C Dark Spot Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Poncirus Trifoliata Fruit Extract
Function:
Origin:
Propanediol
Function:
Origin:
Glycerin
Function:
Origin:
Neopentyl Glycol Dicaprate
Function:
Origin:
Niacinamide
Function:
Origin:
Water
Function:
Origin:
Betaine
Function:
Origin:
Pentylene Glycol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Panthenol
Function:
Origin:
Ascorbyl Tetraisopalmitate
Function:
Origin:
Terminalia Ferdinandiana Fruit Extract
Function:
Origin:
Tranexamic Acid
Function:
Origin:
Tocopherol
Function:
Origin:
Simmondsia Chinensis (Jojoba) Seed Oil
Function:
Origin:
Macadamia Integrifolia Seed Oil
Function:
Origin:
Chondrus Crispus Extract
Function:
Origin:
Saccharum Officinarum (Sugarcane) Extract
Function:
Origin:
Melia Azadirachta Flower Extract
Function:
Origin:
Melia Azadirachta Leaf Extract
Function:
Origin:
Curcuma Longa (Turmeric) Root Extract
Function:
Origin:
Ocimum Sanctum Leaf Extract
Function:
Origin:
Theobroma Cacao (Cocoa) Seed Extract
Function:
Origin:
Corallina Officinalis Extract
Function:
Origin:
Tromethamine
Function:
Origin:
Sodium PCA
Function:
Origin:
Arbutin
Function:
Origin:
Adenosine
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Sodium Phytate
Function:
Origin:
Dextrin
Function:
Origin:
Behenyl Alcohol
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Carbomer
Function:
Origin:

Ratings

All humectants
16.1
6
4
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 16.1 10
10.0
6
4
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
5.3
Ingredient Est. % Benchmark Humectancy
6
4
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 16.1 10
10
All humectants
16.1
6
4
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
2 /10 1 0.3 0.6
n/a
- 0.3 -
n/a
- 0.3 -
Total
3.6
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Ascorbyl Tetraisopalmitate
0.6
Ingredient anti-wrinkle power
2 /10
when present at, %
1
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3.6
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.3 3 Rich in antioxidants
All antioxidants
5.3
Niacinamide
2
Ascorbyl Tetraisopalmitate
0.3
Terminalia Ferdinandiana Fruit Extract
0.3
Tocopherol
0.3
Saccharum Officinarum (Sugarcane) Extract
0.3
Melia Azadirachta Flower Extract
0.3
Melia Azadirachta Leaf Extract
0.3
Curcuma Longa (Turmeric) Root Extract
0.3
Ocimum Sanctum Leaf Extract
0.3
Theobroma Cacao (Cocoa) Seed Extract
0.3
Corallina Officinalis Extract
0.3
Arbutin
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
All soothing 3.2 5 No
All soothing
3.2
2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Poncirus Trifoliata Fruit Extract
Est. %75
Function
Origin
Poncirus Trifoliata Fruit Extract
Propanediol
Est. %6
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Neopentyl Glycol Dicaprate
Est. %3
Function
Origin
Neopentyl Glycol Dicaprate
Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Water
Est. %1.5
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Betaine
Est. %1.3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Pentylene Glycol
Est. %1
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Ascorbyl Tetraisopalmitate
Est. %0.3
Function
Origin
Ascorbyl Tetraisopalmitate

Ascorbyl Tetraisopalmitate (ATIP) is an oil-soluble derivative of ascorbic acid, or vitamin C. It is more stable than ascorbic acid, with studies supporting its collagen-boosting and anti-pigment effects.

Terminalia Ferdinandiana Fruit Extract
Est. %0.3
Function
Origin
Terminalia Ferdinandiana Fruit ExtractExtracted from the fruits of the Kakadu plum (which is the richest source of vitamin C among all plants) this ingredient acts as an excellent antioxidant. Besides this, it is also an antimicrobial agent with some humectant properties.
Tranexamic Acid
Est. %0.3
Function
Origin
Tranexamic AcidA synthetic amino acid that is used as an astringent to stop the bleeding from small cuts. It also has proven anti-pigment and redness-reducing effects.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Simmondsia Chinensis (Jojoba) Seed Oil
Est. %0.3
Function
Origin
Simmondsia Chinensis (Jojoba) Seed OilA liquid plant wax, also known as Jojoba oil, pressed from the seeds of Simmondsia chinensis. These seeds can contain up to 50% of liquid wax. It is used as an occlusive moisturizer, emollient, and emulsifier.
Macadamia Integrifolia Seed Oil
Est. %0.3
Function
Origin
Macadamia Integrifolia Seed OilExtracted from macadamia nuts, this emollient and occlusive moisturizing oil is composed mostly of oleic and palmitoleic fatty acids. It is suitable for dry and eczema-prone skin.
Chondrus Crispus Extract
Est. %0.3
Function
Origin
Chondrus Crispus ExtractAn extract from the species of red marine algae called Irish moss or carrageen moss. It is edible and widely used to produce carrageenan, a polysaccharide with humectant moisturizing and soothing properties.
Saccharum Officinarum (Sugarcane) Extract
Est. %0.3
Function
Origin
Saccharum Officinarum (Sugarcane) ExtractAn antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Melia Azadirachta Flower Extract
Est. %0.3
Function
Origin
Melia Azadirachta Flower ExtractAn antioxidant extract derived from the flowers of the Indian lilac, also known as Neem. It is often used in traditional medicine in India. The Neem flower extracts contain limonoids, which are currently under research for their anti-pigment activity.
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
Melia Azadirachta Leaf ExtractAn antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Curcuma Longa (Turmeric) Root Extract
Est. %0.3
Function
Origin
Curcuma Longa (Turmeric) Root ExtractAn extract derived from the thick roots of curcuma (turmeric), a famous yellow spice and a major ingredient in curry powder. It is used in skincare for its proven antioxidant and anti-inflammatory properties.
Ocimum Sanctum Leaf Extract
Est. %0.3
Function
Origin
Ocimum Sanctum Leaf ExtractAn extract derived from the leaves of Holy Basil, also known as Tulsi, a traditional herb used in Ayurveda medicine. It contains antioxidant and anti-inflammatory rosmarinic acid, galic acid, flavonoids, and a sweet-scented essential oil.
Theobroma Cacao (Cocoa) Seed Extract
Est. %0.3
Function
Origin
Theobroma Cacao (Cocoa) Seed ExtractA cocoa beans extract that contains caffeine and astringent and antioxidant flavonols and tannins.
Corallina Officinalis Extract
Est. %0.3
Function
Origin
Corallina Officinalis ExtractAn extract from red marine alga, Corallina officinalis is used in skincare for its antioxidant properties. It also contains an immense amount of calcium and special, sulfur-containing polysaccharides.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Sodium PCA
Est. %0.3
Function
Origin
Sodium PCAOne of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Arbutin
Est. %0.3
Function
Origin
ArbutinOne of the few potent anti-pigment compounds found naturally in bearberry or cranberry leaves. When applied to the skin, this ingredient converts into hydroquinone, with tyrosinase inhibiting effects.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Sodium Phytate
Est. %0.3
Function
Origin
Sodium PhytateSodium phytate is a chelating agent that serves to remove heavy metal ions from water. Removing metal ions helps other ingredients, such as antioxidants and preservatives, to perform better and keep products from separating.
Dextrin
Est. %0.3
Function
Origin
DextrinA partially hydrolyzed potato starch, most commonly used as a viscosity controlling and binding agent. When dispersed into water, it can create textures ranging from a thick paste to a soft gel.
Behenyl Alcohol
Est. %0.3
Function
Origin
Behenyl AlcoholA fatty alcohol with emollient properties. It is used as a co-emulsifier and thickener and tends to result in a product with a smooth and creamy application texture.
Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.