LETIPharma Letisr Anti-Redness Serum Review

LETIPharma Letisr Anti-Redness Serum
7.4
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
4.9 Occlusivity icon Occlusivity
2.1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does LETIPharma Letisr Anti-Redness Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what LETIPharma Letisr Anti-Redness Serum has to offer:
 
  • Significant moisturizing. It has a moisturizing rating of 7.4 out of 10.
  • Modest anti-wrinkle efficacy: LETIPharma Letisr Anti-Redness Serum has an anti-wrinkle rating of 2.1 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Key Benefits of LETIPharma Letisr Anti-Redness Serum

 
These are the key benefits you can expect from using LETIPharma Letisr Anti-Redness Serum:
 

Perfect Moisturizer for Normal to Dry Skin with a balanced texture, neither too light nor too heavy

According to CreamScan analysis, LETIPharma Letisr Anti-Redness Serum is highly moisturizing, with a moisturizing rating of 7.4 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%) and Butylene Glycol (est. ≈2.0%), and a moderate occlusivity of 4.9 out of 10, mainly due to the high content of Plukenetia Volubilis Seed Oil (est. ≈4.0%) and Ribes Nigrum (Black Currant) Seed Oil (est. ≈3.0%).

This type of moisturizer is ideal for people with normal skin who want maximum hydration in a formula with a balanced texture - neither too light nor too heavy. It combines a high concentration of humectants with a significant amount of occlusive ingredients to deliver effective dual-action moisturizing for normal skin.

This product may also be a good choice for people with normal to dry skin for daily hydration, as it balances significant moisturizing potential with a balanced texture, neither too light nor too heavy.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, LETIPharma Letisr Anti-Redness Serum has a modest level of anti-wrinkle efficacy, rated 2.1 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈1.0%),
     one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
  • Ascorbyl Tetraisopalmitate (est. ≈0.3%),
     the only derivative of ascorbic acid with solid evidence of anti-wrinkle efficacy. A single clinical study involving 23 participants (Mariko et al.) demonstrated that a cream with 1% ATIP reduced the average depth of periorbital wrinkles by 6% after 8 weeks of use, compared to a vehicle (the same formulation without ATIP).
Among others, LETIPharma Letisr Anti-Redness Serum also contains some ingredients marketed often as effective in reducing wrinkles, specifically Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, and Palmitoyl Tripeptide-1. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that LETIPharma Letisr Anti-Redness Serum is rich (> 3%) in antioxidants, specifically Plukenetia Volubilis Seed Oil (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of LETIPharma Letisr Anti-Redness Serum

 
Here’s an overview of the pros and cons of LETIPharma Letisr Anti-Redness Serum to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Perfect for moisturizing normal skin
  • Balanced texture, neither too light nor too heavy
  • Can enhance the moisturizing efficacy of a skincare routine for dry skin
  • Offers modest anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage such as UV radiation and pollution

Cons: 

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Plukenetia Volubilis Seed Oil
Function:
Origin:
Ribes Nigrum (Black Currant) Seed Oil
Function:
Origin:
Butylene Glycol
Function:
Origin:
Dimethicone
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables
Function:
Origin:
Niacinamide
Function:
Origin:
Panthenol
Function:
Origin:
Polymethylsilsesquioxane
Function:
Origin:
Octyldodecanol
Function:
Origin:
Polyacrylate Crosspolymer-6
Function:
Origin:
Butyrospermum Parkii (Shea) Butter Extract
Function:
Origin:
Sodium Dextran Sulfate
Function:
Origin:
Sodium Methylesculetin Acetate
Function:
Origin:
Octyldodecyl Xyloside
Function:
Origin:
Hordeum Vulgare Cera
Function:
Origin:
Argania Spinosa Kernel Oil
Function:
Origin:
Chlorella Vulgaris Extract
Function:
Origin:
Rutin
Function:
Origin:
Phaseolus Lunatus (Green Bean) Seed Extract
Function:
Origin:
Allantoin
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Tocopherol
Function:
Origin:
Ascorbyl Tetraisopalmitate
Function:
Origin:
Hydrolyzed Algin
Function:
Origin:
Pisum Sativum (Pea) Extract
Function:
Origin:
Biosaccharide Gum-2
Function:
Origin:
Acetyl Tetrapeptide-15
Function:
Origin:
Palmitoyl Tripeptide-5
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Citric Acid
Function:
Origin:
Sodium Citrate
Function:
Origin:
Cetyl Hydroxyethylcellulose
Function:
Origin:
Mannitol
Function:
Origin:
Trisodium Ethylenediamine Disuccinate
Function:
Origin:
Cyclodextrin
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Lactic Acid
Function:
Origin:
Dipotassium Phosphate
Function:
Origin:
Diethylhexyl Syringylidenemalonate
Function:
Origin:
p-Anisic Acid
Function:
Origin:
Fragrance
Function:
Origin:
Sodium Hydroxide
Function:
Origin:

Ratings

All humectants
10.8
6
2
1
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
9.7
4.0
3.0
1.5
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
7.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.8 10
10.0
6
2
1
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 9.7 20
4.9
4.0
3.0
1.5
0.3
0.3
0.3
0.3
Moisturizing rating
7.4
Ingredient Est. % Benchmark Humectancy
6
2
1
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 10.8 10
10
All humectants
10.8
6
2
1
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
3
1.5
0.3
0.3
0.3
0.3
All occlusives 9.7 20
4.9
All occlusives
9.7
4.0
3.0
1.5
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1 1.5
2 /10 1 0.3 0.6
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.1
Niacinamide
1.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1
Ascorbyl Tetraisopalmitate
0.6
Ingredient anti-wrinkle power
2 /10
when present at, %
1
in this formula, est. %
0.3
Palmitoyl Tripeptide-5
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.1
Ingredient Est. % Benchmark
Rich in Antioxidants
4
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 8 3 Rich in antioxidants
All antioxidants
8
Plukenetia Volubilis Seed Oil
4
Niacinamide
1
Ascorbyl Tetraisopalmitate
0.3
Argania Spinosa Kernel Oil
0.3
Chlorella Vulgaris Extract
0.3
Rutin
0.3
Tocopheryl Acetate
0.3
Tocopherol
0.3
Hydrolyzed Algin
0.3
Mannitol
0.3
Diethylhexyl Syringylidenemalonate
0.3
p-Anisic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.3
1
0.3
0.3
0.3
All soothing 3.2 5 No
All soothing
3.2
1.3
1
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Plukenetia Volubilis Seed Oil
Est. %4
Function
Origin
Plukenetia Volubilis Seed OilAn occlusive moisturizing fatty oil derived from the seeds of a South American tree known as Inca nut. It is rich in emollient alpha-linolenic acid, linoleic acid, vitamin E, and various phenolic compounds.
Ribes Nigrum (Black Currant) Seed Oil
Est. %3
Function
Origin
Ribes Nigrum (Black Currant) Seed OilA richly emollient and occlusive moisturizing fatty oil extracted from black currant seeds. It has a unique content of polyunsaturated fatty acids and is suitable for oily and acne-prone skin.
Butylene Glycol
Est. %2
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Dimethicone
Est. %1.5
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables
Est. %1.3
Function
Origin
Helianthus Annuus (Sunflower) Seed Oil UnsaponifiablesA strongly emollient and occlusive moisturizing fraction of sunflower oil that consists of waxes, sterols, phospholipids, and vitamin E.
Niacinamide
Est. %1
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Polymethylsilsesquioxane
Est. %0.3
Function
Origin
PolymethylsilsesquioxaneA type of spherical powder that functions on a ball-bearing effect in which the tiny microspheres roll around on the skin and create lubricity. Polymethylsilsesquioxane offers extra slip to skincare products and makes the skin feel soft and smooth.
Octyldodecanol
Est. %0.3
Function
Origin
OctyldodecanolAn emollient fatty alcohol that spreads easily without leaving a greasy residue on the skin. It is also used as a solvent and dispersing agent for other ingredients.
Polyacrylate Crosspolymer-6
Est. %0.3
Function
Origin
Polyacrylate Crosspolymer-6A polymeric ingredient that works best in water-based formulas to create gel textures. It helps to stabilize emulsions and control viscosity.
Butyrospermum Parkii (Shea) Butter Extract
Est. %0.3
Function
Origin
Butyrospermum Parkii (Shea) Butter Extract

For the most part, shea butter extract has the same composition and uses as the regular shea butter. It is used in skincare products as an emollient ingredient.

Sodium Dextran Sulfate
Est. %0.3
Function
Origin
Sodium Dextran Sulfate
Sodium Methylesculetin Acetate
Est. %0.3
Function
Origin
Sodium Methylesculetin Acetate
Octyldodecyl Xyloside
Est. %0.3
Function
Origin
Octyldodecyl Xyloside
Hordeum Vulgare Cera
Est. %0.3
Function
Origin
Hordeum Vulgare Cera
Argania Spinosa Kernel Oil
Est. %0.3
Function
Origin
Argania Spinosa Kernel OilA fatty oil from Moroccan argan tree kernels commonly used as an occlusive moisturizer and emollient. Its uniqueness comes from its compounds: vitamin E, phospholipids, phenolic compounds, and rare phytosterols with antioxidant and emollient effects.
Chlorella Vulgaris Extract
Est. %0.3
Function
Origin
Chlorella Vulgaris ExtractA dried mass of tiny, single-cell green algae. It is widely used as a food source or dietary supplement since it is rich in proteins, amino acids, minerals, and vitamins. This dark green extract is used as an antioxidant agent in skincare.
Rutin
Est. %0.3
Function
Origin
Rutin
Phaseolus Lunatus (Green Bean) Seed Extract
Est. %0.3
Function
Origin
Phaseolus Lunatus (Green Bean) Seed Extract
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Ascorbyl Tetraisopalmitate
Est. %0.3
Function
Origin
Ascorbyl Tetraisopalmitate

Ascorbyl Tetraisopalmitate (ATIP) is an oil-soluble derivative of ascorbic acid, or vitamin C. It is more stable than ascorbic acid, with studies supporting its collagen-boosting and anti-pigment effects.

Hydrolyzed Algin
Est. %0.3
Function
Origin
Hydrolyzed AlginA humectant moisturizing mixture of algae-based polysaccharides, also known as alginate, that have undergone the process of hydrolysis.
Pisum Sativum (Pea) Extract
Est. %0.3
Function
Origin
Pisum Sativum (Pea) ExtractAn extract derived from peas that contains many proteins with humectant moisturizing properties. Patents have claimed that it is able to stimulate cell renewal and increase melanin production.
Biosaccharide Gum-2
Est. %0.3
Function
Origin
Biosaccharide Gum-2
Acetyl Tetrapeptide-15
Est. %0.3
Function
Origin
Acetyl Tetrapeptide-15

Description is coming soon

Palmitoyl Tripeptide-5
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-5

A small synthetic peptide that signals the skin to produce more collagen. It has been clinically tested and proven to reduce skin roughness and the appearance of wrinkles.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Cetyl Hydroxyethylcellulose
Est. %0.3
Function
Origin
Cetyl HydroxyethylcelluloseA naturally-derived polymer that helps products feel buttery and bouncy and can reduce stringiness in a formula.
Mannitol
Est. %0.3
Function
Origin
MannitolA sweet-tasting, sugar-derived, humectant alcohol that can stabilize a skincare formula and offer some antioxidant and soothing properties.
Trisodium Ethylenediamine Disuccinate
Est. %0.3
Function
Origin
Trisodium Ethylenediamine DisuccinateA chelating agent that disables harmful heavy metal ions present in skincare.
Cyclodextrin
Est. %0.3
Function
Origin
CyclodextrinA naturally derived ingredient with the ability to absorb other compounds and remove harmful metal ions from water.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Dipotassium Phosphate
Est. %0.3
Function
Origin
Dipotassium Phosphate
Diethylhexyl Syringylidenemalonate
Est. %0.3
Function
Origin
Diethylhexyl Syringylidenemalonate
p-Anisic Acid
Est. %0.3
Function
Origin
p-Anisic AcidA simple phenolic acid with antioxidant and antimicrobial properties that is used as a preservative. It has a faint, sweet aroma and can be found in anise, fennel, and cocoa seeds.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.