Genabelle PDRN Rejuvenating Cream Review

Genabelle PDRN Rejuvenating Cream
7.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
4.5 Occlusivity icon Occlusivity
2.2Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Genabelle PDRN Rejuvenating Cream Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Genabelle PDRN Rejuvenating Cream has to offer:
 
  • Significant moisturizing. It has a moisturizing rating of 7.2 out of 10.
  • Modest anti-wrinkle efficacy: Genabelle PDRN Rejuvenating Cream has an anti-wrinkle rating of 2.2 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Soothing: Genabelle PDRN Rejuvenating Cream contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Key Benefits of Genabelle PDRN Rejuvenating Cream

 
These are the key benefits you can expect from using Genabelle PDRN Rejuvenating Cream:
 

Perfect Moisturizer for Normal to Dry Skin with a Balanced Texture, Neither Too Light nor Too Heavy

According to CreamScan analysis, Genabelle PDRN Rejuvenating Cream is highly moisturizing, with a moisturizing rating of 7.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%) and Glyceryl Glucoside (est. ≈2.0%), and a moderate occlusivity of 4.5 out of 10, mainly due to the high content of Phenyl Trimethicone (est. ≈4.0%) and Oenothera Biennis (Evening Primrose) Oil (est. ≈3.0%).

This type of moisturizer is ideal for people with normal skin who want maximum hydration in a formula with a balanced texture - neither too light nor too heavy. It combines a high concentration of humectants with a significant amount of occlusive ingredients to deliver effective dual-action moisturizing for normal skin.

This product may also be a good choice for people with normal to dry skin for daily hydration, as it balances significant moisturizing potential with a balanced texture, neither too light nor too heavy.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Genabelle PDRN Rejuvenating Cream has a modest level of anti-wrinkle efficacy, rated 2.2 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈1.5%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Genabelle PDRN Rejuvenating Cream also contains some ingredients marketed often as effective in reducing wrinkles, specifically Centella Asiatica Extract, Adenosine, and Acetyl Hexapeptide-8. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Genabelle PDRN Rejuvenating Cream is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈1.5%), Chamomilla Recutita (Matricaria) Flower Extract (est. ≈1.0%), Centella Asiatica Extract (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin Soothing and Calming Potential

Based on the ingredient list analysis, Genabelle PDRN Rejuvenating Cream is rich (> 5%) in soothing ingredients, particularly Oenothera Biennis (Evening Primrose) Oil (est. ≈3.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Genabelle PDRN Rejuvenating Cream

 
Here’s an overview of the pros and cons of Genabelle PDRN Rejuvenating Cream to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Perfect for moisturizing normal skin
  • Balanced texture, neither too light nor too heavy
  • Offers modest anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
  • Potentially soothing, as it contains a high concentration of soothing ingredients, specifically Oenothera Biennis (Evening Primrose) Oil

Cons: 

  • We couldn't find any

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Phenyl Trimethicone
Function:
Origin:
Oenothera Biennis (Evening Primrose) Oil
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Glyceryl Glucoside
Function:
Origin:
Niacinamide
Function:
Origin:
Beeswax
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Portulaca Oleracea Extract
Function:
Origin:
Vitex Agnus-Castus Extract
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Dimethicone
Function:
Origin:
Dimethicone/Vinyl Dimethicone Crosspolymer
Function:
Origin:
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Function:
Origin:
Butylene Glycol
Function:
Origin:
Ceramide NP
Function:
Origin:
Sodium DNA
Function:
Origin:
Sodium Polyacrylate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Adenosine
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Oligopeptide-127 rh-Oligopeptide-1
Function:
Origin:
Arginine
Function:
Origin:
Carbomer
Function:
Origin:
Tocopherol
Function:
Origin:
Tranexamic Acid
Function:
Origin:
Trideceth-6
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Hydrogenated Polydecene
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
Disodium EDTA
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
11.0
6
2
1.5
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
8.9
4.0
3.0
1.3
0.3
0.3
Benchmark
20
Moisturizing rating
7.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 11.0 10
10.0
6
2
1.5
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 8.9 20
4.5
4.0
3.0
1.3
0.3
0.3
Moisturizing rating
7.2
Ingredient Est. % Benchmark Humectancy
6
2
1.5
0.3
0.3
0.3
0.3
0.3
All humectants 11.0 10
10
All humectants
11.0
6
2
1.5
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
3
1.3
0.3
0.3
All occlusives 8.9 20
4.5
All occlusives
8.9
4.0
3.0
1.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1.5 2.2
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.2
Niacinamide
2.2
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1.5
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.2
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1
0.3
0.3
0.3
0.3
0.3
All antioxidants 4 3 Rich in antioxidants
All antioxidants
4
Niacinamide
1.5
Chamomilla Recutita (Matricaria) Flower Extract
1
Centella Asiatica Extract
0.3
Portulaca Oleracea Extract
0.3
Sodium Hyaluronate
0.3
Tocopherol
0.3
Hydroxyacetophenone
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
1.5
1
0.3
0.3
All soothing 6.1 5 Rich in soothing
All soothing
6.1
3
1.5
1
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Dipropylene Glycol
Est. %9
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Phenyl Trimethicone
Est. %4
Function
Origin
Phenyl TrimethiconeA silicone fluid that is used as an occlusive moisturizer. It applies smoothly to the skin and reduces the tack associated with organic oils.
Oenothera Biennis (Evening Primrose) Oil
Est. %3
Function
Origin
Oenothera Biennis (Evening Primrose) OilAn occlusive moisturizing and emollient fatty oil expressed from the seeds of a yellow-flowered plant which often opens its flowers in the evening (hence the name). It is light and suitable for problematic, eczematous, and inflammation-prone skin.
Cetearyl Alcohol
Est. %2.5
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Glyceryl Glucoside
Est. %2
Function
Origin
Glyceryl Glucoside
Niacinamide
Est. %1.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Beeswax
Est. %1.3
Function
Origin
BeeswaxA waxy substance made by bees while they are building their honeycombs. It is an occlusive moisturizing and emollient ingredient with wound healing and antimicrobial properties similar to those of honey. Its bleached, purified form is called Cera alba.
Chamomilla Recutita (Matricaria) Flower Extract
Est. %1
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Portulaca Oleracea Extract
Est. %0.3
Function
Origin
Portulaca Oleracea ExtractDerived from green or common purslane, this moisturizing extract is particularly rich in alpha-linolenic acid, an omega-3 fatty acid, and contains antioxidant glutathione and vitamin E. As a herbal medicine, it is believed to treat headaches and inflammation.
Vitex Agnus-Castus Extract
Est. %0.3
Function
Origin
Vitex Agnus-Castus Extract
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Dimethicone/Vinyl Dimethicone Crosspolymer
Est. %0.3
Function
Origin
Dimethicone/Vinyl Dimethicone CrosspolymerThis ingredient can refer to several kinds of dimethicone crosspolymers. Like other silicones, it makes products feel slippery and non-greasy but can also increase the thickness or improve the water-resistance of a formula.
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Est. %0.3
Function
Origin
Lauryl PEG-9 Polydimethylsiloxyethyl DimethiconeA powerful emulsifier with the unique trait of being able to work in both oil- and silicone-based formulas. It can also function as a thickener in low concentrations.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Sodium DNA
Est. %0.3
Function
Origin
Sodium DNA
Sodium Polyacrylate
Est. %0.3
Function
Origin
Sodium PolyacrylateThis white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Oligopeptide-127 rh-Oligopeptide-1
Est. %0.3
Function
Origin
Oligopeptide-127 rh-Oligopeptide-1
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Tranexamic Acid
Est. %0.3
Function
Origin
Tranexamic AcidA synthetic amino acid that is used as an astringent to stop the bleeding from small cuts. It also has proven anti-pigment and redness-reducing effects.
Trideceth-6
Est. %0.3
Function
Origin
Trideceth-6
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Hydrogenated Polydecene
Est. %0.3
Function
Origin
Hydrogenated PolydeceneA clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Hydroxyacetophenone
Est. %0.3
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.