Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment Review

Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment
7.3
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
4.6 Occlusivity icon Occlusivity
Review

Does Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment has to offer:
 
  • Significant moisturizing. It has a moisturizing rating of 7.3 out of 10.

Key Benefits of Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment

 
These are the key benefits you can expect from using Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment:
 

Perfect Moisturizer for Normal to Dry Skin with a balanced texture, neither too light nor too heavy

According to CreamScan analysis, Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment is highly moisturizing, with a moisturizing rating of 7.3 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%) and Butylene Glycol (est. ≈2.0%), and a moderate occlusivity of 4.6 out of 10, mainly due to the high content of Caprylic/Capric Triglyceride (est. ≈4.0%) and Simmondsia Chinensis (Jojoba) Seed Oil (est. ≈3.0%).

This type of moisturizer is ideal for people with normal skin who want maximum hydration in a formula with a balanced texture - neither too light nor too heavy. It combines a high concentration of humectants with a significant amount of occlusive ingredients to deliver effective dual-action moisturizing for normal skin.

This product may also be a good choice for people with normal to dry skin for daily hydration, as it balances significant moisturizing potential with a balanced texture, neither too light nor too heavy.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment

 
CreamScan AI identified a few things to consider before adding Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment to your skincare routine:
 

Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains some ingredients often marketed as effective in reducing wrinkles, specifically Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, and Adenosine. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. 

While this does not categorically exclude the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were accessible to the CreamScan team at the time of publication.

Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment

 
Here’s an overview of the pros and cons of Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Perfect for moisturizing normal skin
  • Balanced texture, neither too light nor too heavy
  • Can enhance the moisturizing efficacy of a skincare routine for dry skin

Cons: 

  • Questionable anti-wrinkle efficacy

Ingredients

Est. % Ingredient Origin Functions
65
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Simmondsia Chinensis (Jojoba) Seed Oil
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycereth-26
Function:
Origin:
Squalane
Function:
Origin:
Stearyl Olivate
Function:
Origin:
Octyldodecyl Olivate
Function:
Origin:
Di-C12-15 Alkyl Fumarate
Function:
Origin:
Dimethicone
Function:
Origin:
Stearic Acid
Function:
Origin:
Palmitoyl Tripeptide-38
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Palmitoyl Oligopeptide
Function:
Origin:
Pantothenic Acid
Function:
Origin:
Rhododendron Ferrugineum Leaf Cell Culture Extract
Function:
Origin:
Globularia Cordifolia Callus Culture Extract
Function:
Origin:
Foeniculum Vulgare (Fennel) Fruit Extract
Function:
Origin:
Humulus Lupulus (Hops) Extract
Function:
Origin:
Melissa Officinalis Leaf Extract
Function:
Origin:
Viscum Album (Mistletoe) Leaf Extract
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Achillea Millefolium Extract
Function:
Origin:
Glycine Soja (Soybean) Sterols
Function:
Origin:
Adenosine
Function:
Origin:
Urea
Function:
Origin:
Allantoin
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Hydroxypropyl Cyclodextrin
Function:
Origin:
Coco-Glucoside
Function:
Origin:
Mica
Function:
Origin:
Titanium Dioxide (CI 77891)
Function:
Origin:
Iron Oxides (CI 77492)
Function:
Origin:
Lecithin
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Lactic Acid
Function:
Origin:
Polysorbate 60
Function:
Origin:
Carbomer
Function:
Origin:
Polysorbate 20
Function:
Origin:
Polymethyl Methacrylate
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Dimethiconol
Function:
Origin:
Polyglyceryl-3 Diisostearate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Arginine
Function:
Origin:
Citrus Paradisi (Grapefruit) Peel Extract
Function:
Origin:
Hydroxypropyl Bislauramide MEA
Function:
Origin:
Lactic Acid/Glycolic Acid Copolymer
Function:
Origin:
Dextran
Function:
Origin:
Disodium EDTA
Function:
Origin:
Isomalt
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:

Ratings

All humectants
12.5
6
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
9.2
4.0
3.0
1.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
7.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.5 10
10.0
6
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 9.2 20
4.6
4.0
3.0
1.3
0.3
0.3
0.3
Moisturizing rating
7.3
Ingredient Est. % Benchmark Humectancy
6
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 12.5 10
10
All humectants
12.5
6
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
3
1.3
0.3
0.3
0.3
All occlusives 9.2 20
4.6
All occlusives
9.2
4.0
3.0
1.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Palmitoyl Tripeptide-38
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Oligopeptide
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
All antioxidants 1.5 3 No
All antioxidants
1.5
Humulus Lupulus (Hops) Extract
0.3
Melissa Officinalis Leaf Extract
0.3
Chamomilla Recutita (Matricaria) Flower Extract
0.3
Sodium Hyaluronate
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 2.4 5 No
All soothing
2.4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Caprylic/Capric Triglyceride
Est. %4
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Simmondsia Chinensis (Jojoba) Seed Oil
Est. %3
Function
Origin
Simmondsia Chinensis (Jojoba) Seed OilA liquid plant wax, also known as Jojoba oil, pressed from the seeds of Simmondsia chinensis. These seeds can contain up to 50% of liquid wax. It is used as an occlusive moisturizer, emollient, and emulsifier.
Butylene Glycol
Est. %2
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycereth-26
Est. %1.5
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Squalane
Est. %1.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Stearyl Olivate
Est. %1
Function
Origin
Stearyl Olivate
Octyldodecyl Olivate
Est. %0.3
Function
Origin
Octyldodecyl Olivate
Di-C12-15 Alkyl Fumarate
Est. %0.3
Function
Origin
Di-C12-15 Alkyl Fumarate
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Stearic Acid
Est. %0.3
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Palmitoyl Tripeptide-38
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-38

A small synthetic peptide that increases the production of collagen, fibronectin, and hyaluronic acid in the skin. It has also been shown to reduce wrinkles in combination with other anti-aging ingredients.

Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Palmitoyl Oligopeptide
Est. %0.3
Function
Origin
Palmitoyl Oligopeptide

This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity.

Pantothenic Acid
Est. %0.3
Function
Origin
Pantothenic AcidAlso known as vitamin B5, this ingredient helps to restore healthy moisturization of the skin and is essential for good skin health. Due to poor stability and skin penetration, panthenol is usually preferred over pantothenic acid.
Rhododendron Ferrugineum Leaf Cell Culture Extract
Est. %0.3
Function
Origin
Rhododendron Ferrugineum Leaf Cell Culture Extract
Globularia Cordifolia Callus Culture Extract
Est. %0.3
Function
Origin
Globularia Cordifolia Callus Culture Extract
Foeniculum Vulgare (Fennel) Fruit Extract
Est. %0.3
Function
Origin
Foeniculum Vulgare (Fennel) Fruit ExtractA fragrant extract derived from fennel that contains a warm, spicy essential oil and an emollient fatty oil.
Humulus Lupulus (Hops) Extract
Est. %0.3
Function
Origin
Humulus Lupulus (Hops) ExtractAn extract from hops flowers. Hops have been used traditionally to treat skin inflammation. The extract is rich in antioxidants and has antifungal and antimicrobial activity.
Melissa Officinalis Leaf Extract
Est. %0.3
Function
Origin
Melissa Officinalis Leaf ExtractA fragrant extract derived from lemon balm leaves with antioxidant and antiviral flavonoids and terpenes. It has a lovely, fresh, lemon-like scent.
Viscum Album (Mistletoe) Leaf Extract
Est. %0.3
Function
Origin
Viscum Album (Mistletoe) Leaf Extract
Chamomilla Recutita (Matricaria) Flower Extract
Est. %0.3
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Achillea Millefolium Extract
Est. %0.3
Function
Origin
Achillea Millefolium ExtractAn extract obtained from the common yarrow. It is full of astringent and anti-inflammatory phytochemicals that help with inflamed skin and wound healing, have soothing and refreshing effects on the skin, and give the product a fresh, green, and spicy scent.
Glycine Soja (Soybean) Sterols
Est. %0.3
Function
Origin
Glycine Soja (Soybean) SterolsA mixture of phytosterols isolated from soybean oil. Phytosterols, when used in skincare products, have emollient properties and can make the skin feel softer and smoother.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Urea
Est. %0.3
Function
Origin
UreaUrea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Hydroxypropyl Cyclodextrin
Est. %0.3
Function
Origin
Hydroxypropyl CyclodextrinA white crystalline powder that can reduce odors coming from other ingredients in a product.
Coco-Glucoside
Est. %0.3
Function
Origin
Coco-GlucosideA mild cleansing and foaming agent. It can be used on its own as a gentle cleanser in a skin cleansing product or can be combined with more powerful cleansing agents, called anionic surfactants, to make them milder on the skin.
Mica
Est. %0.3
Function
Origin
MicaA mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
Titanium Dioxide (CI 77891)One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Iron Oxides (CI 77492)
Est. %0.3
Function
Origin
Iron Oxides (CI 77492)Also known as iron (III) oxide, this ingredient is a yellow-colored pigment that can either be derived from minerals or produced synthetically. It adds yellow tones to cosmetic products.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Polymethyl Methacrylate
Est. %0.3
Function
Origin
Polymethyl MethacrylateA powdered ingredient with an impressive sensory profile that gives off a creamy, sometimes velvety feeling on the skin. It is made up of tiny microspheres that roll smoothly across the skin and create slip and high spreadability.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Dimethiconol
Est. %0.3
Function
Origin
DimethiconolA synthetic dimethicone with rich, non-tacky emolliency. It features the typical sensorial profile of silicones, with high spreadability and a luxurious, oil-free after-feel. Dimethiconol can also serve as an antifoaming agent.
Polyglyceryl-3 Diisostearate
Est. %0.3
Function
Origin
Polyglyceryl-3 DiisostearateA vegetable-based ingredient that stabilizes mixtures of oil and water.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Citrus Paradisi (Grapefruit) Peel Extract
Est. %0.3
Function
Origin
Citrus Paradisi (Grapefruit) Peel Extract
Hydroxypropyl Bislauramide MEA
Est. %0.3
Function
Origin
Hydroxypropyl Bislauramide MEA
Lactic Acid/Glycolic Acid Copolymer
Est. %0.3
Function
Origin
Lactic Acid/Glycolic Acid Copolymer
Dextran
Est. %0.3
Function
Origin
DextranA naturally derived sucrose metabolite that thickens water and bulks emulsions.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Isomalt
Est. %0.3
Function
Origin
IsomaltIsomalt is a mixture of medium-sized sugars (a.k.a. oligosaccharides) that is prepared from sucrose by treatment with enzymes. In skincare products, it acts as a water-binding humectant ingredient that also serves as a bulking and anticaking agent. It has a mildly sweet taste.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.