A small synthetic peptide that increases the production of collagen, fibronectin, and hyaluronic acid in the skin. It has also been shown to reduce wrinkles in combination with other anti-aging ingredients.
Palmitoyl Tripeptide-38 is a short peptide with three amino acids (Lys-Met-Lys) with a palmitic acid on one end for better solubility in oils and increased skin absorption. It is used under the trademarked name MATRIXYL™ synthe'6 and is said to be a pro‐collagen lipopeptide able to increase the production of collagen, fibronectin, and hyaluronic acid.
There have been two clinical evaluations of this ingredient in a mixture with other anti-aging ingredients and both have reported good anti-wrinkle results.
For Palmitoyl Tripeptide-38 as an ingredient on its own, we only have the results from the manufacturer’s tests based on user reviews. 25 women reported various decreases in signs of aging after using a 2% cream.
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