Derm Institute Anti-Oxidant Hydration Cream

Derm Institute Anti-Oxidant Hydration Cream
7.6
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
5.1 Occlusivity icon Occlusivity
2Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does Derm Institute Anti-Oxidant Hydration Cream work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Derm Institute Anti-Oxidant Hydration Cream:

  • Significant moisturizing. It has a moisturizing rating of 7.6 out of 10.
  • Some anti-wrinkle efficacy: Derm Institute Anti-Oxidant Hydration Cream has an anti-wrinkle rating of 2.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Perfect moisturizer for normal to dry skin with a relatively lightweight texture

According to CreamScan analysis, Derm Institute Anti-Oxidant Hydration Cream is highly moisturizing, with a moisturizing rating of 7.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Butylene Glycol (est. ≈9.0%), and a moderate occlusivity of 5.1 out of 10, mainly due to the high content of Simmondsia Chinensis (Jojoba) Seed Oil (est. ≈6.0%).

This type of moisturizer is ideal for people with normal skin. It combines a high concentration of humectants with a significant amount of occlusive ingredients to deliver effective dual-action moisturizing for normal skin.

This product may also be a good choice for people with normal to dry skin for daily hydration, as it balances significant moisturizing potential with a relatively lightweight texture.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, Derm Institute Anti-Oxidant Hydration Cream has a slight anti-wrinkle rating of 2.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈1.3%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Derm Institute Anti-Oxidant Hydration Cream also contains contains Camellia Sinensis Leaf Extract and Melia Azadirachta Leaf Extract, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Derm Institute Anti-Oxidant Hydration Cream is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈1.3%), Crithmum Maritimum Extract (est. ≈0.3%), Tocopheryl Acetate (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
2
1.9
1.8
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Simmondsia Chinensis (Jojoba) Seed Oil
Function:
Origin:
Isododecane
Function:
Origin:
Sclerotium Gum
Function:
Origin:
Cetyl Ethylhexanoate
Function:
Origin:
Triethylhexanoin
Function:
Origin:
Octyldodecyl Stearoyl Stearate
Function:
Origin:
Niacinamide
Function:
Origin:
Saccharide Isomerate
Function:
Origin:
PEG-30 Dipolyhydroxystearate
Function:
Origin:
Propanediol
Function:
Origin:
Disodium Phosphate
Function:
Origin:
Xanthan Gum
Function:
Origin:
Sodium Phosphate
Function:
Origin:
Glyceryl Caprylate
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Crithmum Maritimum Extract
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Panthenol
Function:
Origin:
Alpinia Galanga Leaf Extract
Function:
Origin:
Sodium Chloride
Function:
Origin:
Lecithin
Function:
Origin:
Oleic Acid
Function:
Origin:
Bisabolol
Function:
Origin:
Limnanthes Alba (Meadowfoam) Seed Oil
Function:
Origin:
Ceramide NP
Function:
Origin:
Ceramide AP
Function:
Origin:
Ceramide EOP
Function:
Origin:
Phytosphingosine
Function:
Origin:
Cholesterol
Function:
Origin:
Bacopa Monnieri Extract
Function:
Origin:
Angelica Acutiloba Root Extract
Function:
Origin:
Poria Cocos Extract
Function:
Origin:
Algae Extract
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Sodium Citrate
Function:
Origin:
Arginine
Function:
Origin:
Allantoin
Function:
Origin:
Fragrance
Function:
Origin:
Melia Azadirachta Leaf Extract
Function:
Origin:
Chlorphenesin
Function:
Origin:
Hydroxypropyltrimonium Hyaluronate
Function:
Origin:
Acetyl Tetrapeptide-17
Function:
Origin:
Colloidal Platinum
Function:
Origin:
Capryloyl Heptapeptide-12
Function:
Origin:
Gold (CI 77480)
Function:
Origin:
Resveratrol
Function:
Origin:
Pyridoxine HCl
Function:
Origin:

Ratings

All humectants
13.7
9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
10.2
6.0
1.8
1.5
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
7.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 13.7 10
10.0
9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 10.2 20
5.1
6.0
1.8
1.5
0.3
0.3
0.3
Moisturizing rating
7.6
Ingredient Est. % Benchmark Humectancy
9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 13.7 10
10
All humectants
13.7
9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
6
1.8
1.5
0.3
0.3
0.3
All occlusives 10.2 20
5.1
All occlusives
10.2
6.0
1.8
1.5
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1.3 2
n/a
- 0.3 -
n/a
- 0.3 -
Total
2
Niacinamide
2
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2
Ingredient Est. % Benchmark
Rich in Antioxidants
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 4 3 Rich in antioxidants
All antioxidants
4
Niacinamide
1.3
Crithmum Maritimum Extract
0.3
Tocopheryl Acetate
0.3
Angelica Acutiloba Root Extract
0.3
Algae Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Sodium Hyaluronate
0.3
Melia Azadirachta Leaf Extract
0.3
Colloidal Platinum
0.3
Resveratrol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 3.7 5 No
All soothing
3.7
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %9
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Simmondsia Chinensis (Jojoba) Seed Oil
Est. %6
Function
Origin
Simmondsia Chinensis (Jojoba) Seed OilA liquid plant wax, also known as Jojoba oil, pressed from the seeds of Simmondsia chinensis. These seeds can contain up to 50% of liquid wax. It is used as an occlusive moisturizer, emollient, and emulsifier.
Isododecane
Est. %4
Function
Origin
IsododecaneAn emollient derived from petroleum with high spreadability. It is often used as a replacement for oils and silicones because it leaves no residue behind on the skin. When a product is labeled as “oil-free” it may contain isododecane instead of heavier oils.
Sclerotium Gum
Est. %2
Function
Origin
Sclerotium GumA thickener with a silky, velvety feel that many manufacturers use as an alternative to silicones.
Cetyl Ethylhexanoate
Est. %1.9
Function
Origin
Cetyl EthylhexanoateA clear, pale yellow liquid, that functions as an emollient and a solvent, meaning that it is useful for dissolving oil-soluble ingredients.
Triethylhexanoin
Est. %1.8
Function
Origin
TriethylhexanoinAn occlusive and emollient ester of glycerin and a fatty acid. It is easily spreadable and does not leave a sticky after-feel.
Octyldodecyl Stearoyl Stearate
Est. %1.5
Function
Origin
Octyldodecyl Stearoyl Stearate
Niacinamide
Est. %1.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Saccharide Isomerate
Est. %1
Function
Origin
Saccharide IsomerateA naturally-derived humectant that provides moisturization at low levels and is less sticky than other humectants like glycerin.
PEG-30 Dipolyhydroxystearate
Est. %0.3
Function
Origin
PEG-30 Dipolyhydroxystearate
Propanediol
Est. %0.3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Disodium Phosphate
Est. %0.3
Function
Origin
Disodium PhosphateAn inorganic ingredient primarily used in skincare products as a pH adjuster.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Sodium Phosphate
Est. %0.3
Function
Origin
Sodium PhosphateA sodium salt of phosphoric acid that increases pH.
Glyceryl Caprylate
Est. %0.3
Function
Origin
Glyceryl CaprylateA waxy solid derived from vegetable oils that has emollient and emulsifying properties. It is also known to boost the efficacy of organic acid preservatives by destabilizing the microbe's cell membrane.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Crithmum Maritimum Extract
Est. %0.3
Function
Origin
Crithmum Maritimum ExtractDerived from sea fennel, this extract contains antioxidant flavonoids and organic acids and has a spicy, herbaceous aroma.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Alpinia Galanga Leaf Extract
Est. %0.3
Function
Origin
Alpinia Galanga Leaf Extract
Sodium Chloride
Est. %0.3
Function
Origin
Sodium Chloride

You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions.

Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Oleic Acid
Est. %0.3
Function
Origin
Oleic AcidAn omega-9 fatty acid commonly found in vegetable oils. It is occlusive moisturizing, emollient and emulsifying.
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Limnanthes Alba (Meadowfoam) Seed Oil
Est. %0.3
Function
Origin
Limnanthes Alba (Meadowfoam) Seed OilA fatty oil expressed from the seeds of meadowfoam. It is used in skincare as an occlusive moisturizer and emollient that leaves the skin feeling soft and silky after application.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Ceramide AP
Est. %0.3
Function
Origin
Ceramide APPreviously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Ceramide EOP
Est. %0.3
Function
Origin
Ceramide EOP

Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.

Phytosphingosine
Est. %0.3
Function
Origin
PhytosphingosineA key component of ceramides NP, AP, and EOP. It has barrier repair properties and stimulates the production of the skin’s Natural Moisturizing Factor. Phytosphingosine has strong antimicrobial and anti-inflammatory activity, which can be used to treat acne.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Bacopa Monnieri Extract
Est. %0.3
Function
Origin
Bacopa Monnieri Extract
Angelica Acutiloba Root Extract
Est. %0.3
Function
Origin
Angelica Acutiloba Root ExtractAngelica acutiloba root extract is a pungent, aromatic extract derived from the roots of the Japanese angelica tree. It has soothing effects and can be beneficial for itchy or allergy-prone skin [1]. It also contains antioxidants and protects the skin against UV-induced damage.
Poria Cocos Extract
Est. %0.3
Function
Origin
Poria Cocos Extract
Algae Extract
Est. %0.3
Function
Origin
Algae ExtractThe name describes any extract made from any kind of algae. Algae extracts are moisturizing humectants – the gelatin-like polysaccharides bind and retain water, thereby hydrating the skin. Algae is a rich source of emollient and antioxidant compounds.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
Camellia Sinensis Leaf Extract

An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
Melia Azadirachta Leaf ExtractAn antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Hydroxypropyltrimonium Hyaluronate
Est. %0.3
Function
Origin
Hydroxypropyltrimonium Hyaluronate
Acetyl Tetrapeptide-17
Est. %0.3
Function
Origin
Acetyl Tetrapeptide-17
Colloidal Platinum
Est. %0.3
Function
Origin
Colloidal Platinum
Capryloyl Heptapeptide-12
Est. %0.3
Function
Origin
Capryloyl Heptapeptide-12
Gold (CI 77480)
Est. %0.3
Function
Origin
Gold (CI 77480)

A colorant used in skincare, typically processed into fine particles for uniform dispersion. Its luxurious hue enhances product aesthetics, while its role as a slip and surface modifier improves texture and application. Despite touted anti-aging benefits, definitive scientific evidence is lacking.

Resveratrol
Est. %0.3
Function
Origin
ResveratrolA famous plant-based polyphenol found mainly in red grapes. It is a potent antioxidant, soothing, and wound healing ingredient.
Pyridoxine HCl
Est. %0.3
Function
Origin
Pyridoxine HClA B-vitamin that helps regulate sebum production.