Cetaphil Healthy Renew Purified Peptides Night Cream

Cetaphil Healthy Renew Purified Peptides Night Cream
5.5
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.0 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle

Review

Results you may expect from using Cetaphil Healthy Renew Purified Peptides Night Cream:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Cetaphil Healthy Renew Purified Peptides Night Cream:

  • Moderate moisturizing. It has a moisturizing rating of 5.5 out of 10.
  • Little anti-wrinkle effect: Cetaphil Healthy Renew Purified Peptides Night Cream has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

How moisturizing is it?

Quite moisturizing: Cetaphil Healthy Renew Purified Peptides Night Cream has a moisturizing rating of 5.5 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.0 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Propanediol (est. ≈9.0%) and Panthenol (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Cetaphil Healthy Renew Purified Peptides Night Cream has a minimal anti-wrinkle rating of 0.4 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈0.3%),
 one of the most effective and well-researched anti-wrinkle ingredients.
 
Among others, Cetaphil Healthy Renew Purified Peptides Night Cream also contains Adenosine, an ingredient marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Adenosine provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
60
Water
9
Propanediol
6
Cetyl Ethylhexanoate
4
Dibutyl Adipate
3
Hydrogenated Polydecene
2.5
Coco-Caprylate/Caprate
2
Panthenol
1.5
Polyglyceryl-6 Stearate
1.3
Glycerin
1
Beeswax
0.3
Cetearyl Alcohol
0.3
Niacinamide
0.3
Palmitic Acid
0.3
Stearic Acid
0.3
Butyrospermum Parkii (Shea) Butter
0.3
Glyceryl Stearate
0.3
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
0.3
Carbomer
0.3
Caprylyl Glycol
0.3
Isohexadecane
0.3
Leontopodium Alpinum Extract
0.3
Polyglyceryl-6 Behenate
0.3
Ethylhexylglycerin
0.3
Tromethamine
0.3
Hydrogenated Olive Oil Unsaponifiables
0.3
Oryza Sativa (Rice) Lees Extract
0.3
Tocopheryl Acetate
0.3
Polysorbate 80
0.3
1,2-Hexanediol
0.3
Adenosine
0.3
Sorbitan Oleate
0.3
Citric Acid
0.3
Sodium Benzoate
0.3
Potassium Sorbate
0.3
Hydrolyzed Soy Flour
0.3
Buddleja Davidii Extract
0.3
Thymus Vulgaris (Thyme) Extract
Est. %
Water
Function:
Origin:
Propanediol
Function:
Origin:
Cetyl Ethylhexanoate
Function:
Origin:
Dibutyl Adipate
Function:
Origin:
Hydrogenated Polydecene
Function:
Origin:
Coco-Caprylate/Caprate
Function:
Origin:
Panthenol
Function:
Origin:
Polyglyceryl-6 Stearate
Function:
Origin:
Glycerin
Function:
Origin:
Beeswax
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Niacinamide
Function:
Origin:
Palmitic Acid
Function:
Origin:
Stearic Acid
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Carbomer
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Isohexadecane
Function:
Origin:
Leontopodium Alpinum Extract
Function:
Origin:
Polyglyceryl-6 Behenate
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Tromethamine
Function:
Origin:
Hydrogenated Olive Oil Unsaponifiables
Function:
Origin:
Oryza Sativa (Rice) Lees Extract
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Polysorbate 80
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Adenosine
Function:
Origin:
Sorbitan Oleate
Function:
Origin:
Citric Acid
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Hydrolyzed Soy Flour
Function:
Origin:
Buddleja Davidii Extract
Function:
Origin:
Thymus Vulgaris (Thyme) Extract
Function:
Origin:

Ratings

All humectants
13.2
9
2
1.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.9
1.0
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.5
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 13.2 10
10.0
9
2
1.3
0.3
0.3
0.3
Occlusivity All occlusives 1.9 20
1.0
1.0
0.3
0.3
0.3
Moisturizing rating
5.5
Ingredient Est. % Benchmark Humectancy
9
2
1.3
0.3
0.3
0.3
All humectants 13.2 10
10
All humectants
13.2
9
2
1.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1
0.3
0.3
0.3
All occlusives 1.9 20
1.0
All occlusives
1.9
1.0
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 0.3 0.4
n/a
- 0.3 -
Total
0.4
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
All antioxidants 1.5 3 No
All antioxidants
1.5
Niacinamide
0.3
Leontopodium Alpinum Extract
0.3
Tocopheryl Acetate
0.3
Buddleja Davidii Extract
0.3
Thymus Vulgaris (Thyme) Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
All soothing 2.6 5 No
All soothing
2.6
2
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Propanediol
Est. %9
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Cetyl Ethylhexanoate
Est. %6
Function
Origin
Cetyl EthylhexanoateA clear, pale yellow liquid, that functions as an emollient and a solvent, meaning that it is useful for dissolving oil-soluble ingredients.
Dibutyl Adipate
Est. %4
Function
Origin
Dibutyl AdipateDescription is coming soon
Hydrogenated Polydecene
Est. %3
Function
Origin
Hydrogenated PolydeceneA clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Coco-Caprylate/Caprate
Est. %2.5
Function
Origin
Coco-Caprylate/CaprateA naturally-derived emollient ester. It is a blend of caprylates and caprates and, relative to other emollients, is lightweight and dry on the skin. As a result, coco-caprylate/caprate serves as a natural alternative to volatile silicones.
Panthenol
Est. %2
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Polyglyceryl-6 Stearate
Est. %1.5
Function
Origin
Polyglyceryl-6 StearateDescription is coming soon
Glycerin
Est. %1.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Beeswax
Est. %1
Function
Origin
BeeswaxA waxy substance made by bees while they are building their honeycombs. It is an occlusive moisturizing and emollient ingredient with wound healing and antimicrobial properties similar to those of honey. Its bleached, purified form is called Cera alba.
Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Palmitic Acid
Est. %0.3
Function
Origin
Palmitic AcidA saturated fatty acid used in skincare as a strongly occlusive moisturizer and barrier repairing, emollient ingredient. It is a waxy-looking, white solid. Palmitic acid can be commonly found in animal and vegetable fats, notably palm oil.
Stearic Acid
Est. %0.3
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Isohexadecane
Est. %0.3
Function
Origin
IsohexadecaneA clear, colorless liquid that is commonly used as an emollient. It is made up of pure hydrocarbons and leaves a dry feeling on the skin upon application. It also increases the spreadability of a product.
Leontopodium Alpinum Extract
Est. %0.3
Function
Origin
Leontopodium Alpinum ExtractAn extract from a beautiful alpine plant called Edelweiss. It contains a rare compound called leontopodic acid with antioxidant, antibacterial, and anti-inflammatory properties.
Polyglyceryl-6 Behenate
Est. %0.3
Function
Origin
Polyglyceryl-6 BehenateDescription is coming soon
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Hydrogenated Olive Oil Unsaponifiables
Est. %0.3
Function
Origin
Hydrogenated Olive Oil UnsaponifiablesA strongly emollient fraction of olive oil. It contains sterols and fatty alcohols along with various antioxidant compounds and squalane - which replenishes skin sebum.
Oryza Sativa (Rice) Lees Extract
Est. %0.3
Function
Origin
Oryza Sativa (Rice) Lees ExtractDescription is coming soon
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Polysorbate 80
Est. %0.3
Function
Origin
Polysorbate 80A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Sorbitan Oleate
Est. %0.3
Function
Origin
Sorbitan OleateA vegetable-based ingredient that stabilizes mixtures of oil and water. Sorbitan oleate serves primarily as an emulsifier that produces water-in-oil emulsions.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Hydrolyzed Soy Flour
Est. %0.3
Function
Origin
Hydrolyzed Soy FlourDescription is coming soon
Buddleja Davidii Extract
Est. %0.3
Function
Origin
Buddleja Davidii ExtractAn extract of summer lilac with antioxidant and anti-inflammatory compounds such as iridoids, various terpenes, flavonoids, and phenolic acids. More research is needed in order to evaluate its functions.
Thymus Vulgaris (Thyme) Extract
Est. %0.3
Function
Origin
Thymus Vulgaris (Thyme) ExtractDerived from thyme, this antioxidant, antiseptic and fragrant extract consists mainly of thyme essential oil (with its spicy herbal scent), flavonoids, terpenes, and organic acids.