Celladix Sebum Rebalancing RX 131 Ampoule Review

Celladix Sebum Rebalancing RX 131 Ampoule
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Ingredients

Celladix Sebum Rebalancing RX 131 Ampoule Ingredients

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Full Ingredient List (INCI):

Water, Dipropylene Glycol, Butylene Glycol, Glycereth-26, Niacinamide, Glycerin, Betaine, Phytosterols, Ceramide NP, Squalane, Lauric Acid, Arachidic Acid, Behenic Acid, Beta-Glucan, Paulownia Tomentosa Leaf Extract, Cinnamomum Cassia Bark Extract, Cinnamomum Japonicum Leaf Extract, Cinnamomum Camphora (Camphor) Leaf Extract, Laurus Nobilis Leaf Extract, Coriandrum Sativum (Coriander) Extract, Eucalyptus Globulus Leaf Extract, Scutellaria Baicalensis Root Extract, Machilus Thunbergii Branch Extract, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Polyglyceryl-10 Myristate, Hydroxyacetophenone, Panthenol, Disodium EDTA, Sodium Hyaluronate, Xanthan Gum, Sodium Polyacrylate, Ethylhexylglycerin, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Lavandula Hybrida Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Lavandula Angustifolia (Lavender) Oil, Amyris Balsamifera Bark Oil, Ocimum Basilicum (Basil) Oil, Limonene, Linalool, Adenosine
Review

Does Celladix Sebum Rebalancing RX 131 Ampoule Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Celladix Sebum Rebalancing RX 131 Ampoule has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
✅ Modest anti-wrinkle efficacy: Celladix Sebum Rebalancing RX 131 Ampoule has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection

  

Key Benefits of Celladix Sebum Rebalancing RX 131 Ampoule

 
These are the key benefits you can expect from using Celladix Sebum Rebalancing RX 131 Ampoule:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Celladix Sebum Rebalancing RX 131 Ampoule is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈4.0%), Glycereth-26 (est. ≈3.0%) and Niacinamide (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Celladix Sebum Rebalancing RX 131 Ampoule has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Celladix Sebum Rebalancing RX 131 Ampoule also contains contains Beta-Glucan and Adenosine, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Celladix Sebum Rebalancing RX 131 Ampoule is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Celladix Sebum Rebalancing RX 131 Ampoule

 
Here’s an overview of the pros and cons of Celladix Sebum Rebalancing RX 131 Ampoule to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Celladix Sebum Rebalancing RX 131 Ampoule

 
Based on the ingredient list analysis, CreamScan AI suggests that Celladix Sebum Rebalancing RX 131 Ampoule
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
Celladix Sebum Rebalancing RX 131 Ampoule contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, Celladix Sebum Rebalancing RX 131 Ampoule helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.04
Est. %
Water
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycereth-26
Function:
Origin:
Niacinamide
Function:
Origin:
Glycerin
Function:
Origin:
Betaine
Function:
Origin:
Phytosterols
Function:
Origin:
Ceramide NP
Function:
Origin:
Squalane
Function:
Origin:
Lauric Acid
Function:
Origin:
Arachidic Acid
Function:
Origin:
Behenic Acid
Function:
Origin:
Beta-Glucan
Function:
Origin:
Paulownia Tomentosa Leaf Extract
Function:
Origin:
Cinnamomum Cassia Bark Extract
Function:
Origin:
Cinnamomum Japonicum Leaf Extract
Function:
Origin:
Cinnamomum Camphora (Camphor) Leaf Extract
Function:
Origin:
Laurus Nobilis Leaf Extract
Function:
Origin:
Coriandrum Sativum (Coriander) Extract
Function:
Origin:
Eucalyptus Globulus Leaf Extract
Function:
Origin:
Scutellaria Baicalensis Root Extract
Function:
Origin:
Machilus Thunbergii Branch Extract
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Polyglyceryl-10 Myristate
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
Panthenol
Function:
Origin:
Disodium EDTA
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Xanthan Gum
Function:
Origin:
Sodium Polyacrylate
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
Function:
Origin:
Lavandula Hybrida Oil
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Peel Oil
Function:
Origin:
Lavandula Angustifolia (Lavender) Oil
Function:
Origin:
Amyris Balsamifera Bark Oil
Function:
Origin:
Ocimum Basilicum (Basil) Oil
Function:
Origin:
Limonene
Function:
Origin:
Linalool
Function:
Origin:
Adenosine
Function:
Origin:

Ratings

All humectants
13.6
4
3
2
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 13.6 10
10.0
4
3
2
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
4
3
2
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 13.6 10
10
All humectants
13.6
4
3
2
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
n/a
- 0.3 -
n/a
- 0.04 -
Total
3
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.04
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2
1
0.3
0.3
0.3
0.3
0.3
All antioxidants 4.5 3 Rich in antioxidants
All antioxidants
4.5
Niacinamide
2
Phytosterols
1
Beta-Glucan
0.3
Cinnamomum Japonicum Leaf Extract
0.3
Scutellaria Baicalensis Root Extract
0.3
Hydroxyacetophenone
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
All soothing 3.2 5 No
All soothing
3.2
2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Dipropylene Glycol
Est. %6
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Butylene Glycol
Est. %4
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycereth-26
Est. %3
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Betaine
Est. %1.3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Phytosterols
Est. %1
Function
Origin
PhytosterolsA plant-based version of cholesterol that is used for its emollient properties in skincare. The richest sources of phytosterols are corn, rapeseed, and wheat germ oil.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Squalane
Est. %0.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Lauric Acid
Est. %0.3
Function
Origin
Lauric AcidA fatty acid derived from various vegetable oils such as palm or coconut oil. It helps to maintain the barrier function of the skin and is also used as a cleansing or emulsifying agent. Lauric acid is listed among common comedogenic ingredients by acne.org.
Arachidic Acid
Est. %0.3
Function
Origin
Arachidic Acid
Behenic Acid
Est. %0.3
Function
Origin
Behenic AcidA naturally-occuring ingredient from certain plant oils, behenic acid acts as an emulsifier and surfactant and provides a soft cushiony feeling.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Paulownia Tomentosa Leaf Extract
Est. %0.3
Function
Origin
Paulownia Tomentosa Leaf Extract
Cinnamomum Cassia Bark Extract
Est. %0.3
Function
Origin
Cinnamomum Cassia Bark ExtractA fragrant extract obtained from Chinese cinnamon bark with some added antioxidant and antimicrobial effects. The essential oil is responsible for its cinnamon scent.
Cinnamomum Japonicum Leaf Extract
Est. %0.3
Function
Origin
Cinnamomum Japonicum Leaf Extract
Cinnamomum Camphora (Camphor) Leaf Extract
Est. %0.3
Function
Origin
Cinnamomum Camphora (Camphor) Leaf Extract
Laurus Nobilis Leaf Extract
Est. %0.3
Function
Origin
Laurus Nobilis Leaf Extract
Coriandrum Sativum (Coriander) Extract
Est. %0.3
Function
Origin
Coriandrum Sativum (Coriander) Extract
Eucalyptus Globulus Leaf Extract
Est. %0.3
Function
Origin
Eucalyptus Globulus Leaf ExtractA fragrant extract obtained from the mature leaves of the Eucalyptus tree. It contains cineole, the main constituent of eucalyptus essential oil.
Scutellaria Baicalensis Root Extract
Est. %0.3
Function
Origin
Scutellaria Baicalensis Root ExtractA powerful antioxidant, soothing, and astringent extract derived from the roots of Baikal/Chinese skullcap. It contains various unique flavonoids that are believed to soothe irritated and inflamed skin and protect from UV-induced oxidative damage.
Machilus Thunbergii Branch Extract
Est. %0.3
Function
Origin
Machilus Thunbergii Branch Extract
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Polyglyceryl-10 Myristate
Est. %0.3
Function
Origin
Polyglyceryl-10 MyristateA solubilizer that can help incorporate small amounts of oil to an otherwise watery product while providing lightweight skin feel.
Hydroxyacetophenone
Est. %0.3
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Sodium Polyacrylate
Est. %0.3
Function
Origin
Sodium PolyacrylateThis white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Citrus Aurantium Bergamia (Bergamot) Fruit Oil
Est. %0.3
Function
Origin
Citrus Aurantium Bergamia (Bergamot) Fruit Oil

An essential oil expressed from the peels of the bergamot orange. The scent of bergamot oil is woodier than those of other citrus essential oils. This essential oil is still not recommended if you are sensitive to citrus fruits.

Lavandula Hybrida Oil
Est. %0.3
Function
Origin
Lavandula Hybrida OilA fragrant essential oil distilled from a lavender hybrid of the two most common lavender species: true lavender and spike lavender. It contains linalool and linalyl acetate as well as eucalyptol and camphor, which altogether give it a cooling, lavender scent.
Citrus Aurantium Dulcis (Orange) Peel Oil
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Peel Oil

An essential oil derived from the peels of the sweet orange. It is commonly used as a fragrance because of its pleasant, citrusy scent. The main constituent of the essential oil is limonene (up to 96%).

Lavandula Angustifolia (Lavender) Oil
Est. %0.3
Function
Origin
Lavandula Angustifolia (Lavender) OilAn essential oil derived from common, or true, lavender. It is used in skincare for its lovely, calming scent. Like all essential oils, however, it may cause a contact skin allergy in more sensitive individuals.
Amyris Balsamifera Bark Oil
Est. %0.3
Function
Origin
Amyris Balsamifera Bark OilA fragrant oil derived from the bark of the Amyris tree, also known as torchwood. It gives off a relaxing, woody scent and sometimes substitutes sandalwood oil.
Ocimum Basilicum (Basil) Oil
Est. %0.3
Function
Origin
Ocimum Basilicum (Basil) OilAn essential oil derived from basil. It contains linalool and methyl chavicol which give the oil its characteristic fresh, green aroma.
Limonene
Est. %0.3
Function
Origin
Limonene

One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.

Linalool
Est. %0.3
Function
Origin
LinaloolA fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Adenosine
Est. %0.04
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.