Cell:Monde Nucleic Acid Refreshing Toner

Cell:Monde Nucleic Acid Refreshing Toner
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
4.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Results you may expect from using Cell:Monde Nucleic Acid Refreshing Toner:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Cell:Monde Nucleic Acid Refreshing Toner:

  • Moderate moisturizing. It has a moisturizing rating of 5.1 out of 10.
  • Considerable anti-wrinkle efficacy: Cell:Monde Nucleic Acid Refreshing Toner has an anti-wrinkle rating of 4.5 out of 10, indicating a moderate ability to reduce wrinkles.
  • Soothing: Cell:Monde Nucleic Acid Refreshing Toner contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Cell:Monde Nucleic Acid Refreshing Toner has a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycereth-26 (est. ≈6.0%) and Niacinamide (est. ≈3.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Cell:Monde Nucleic Acid Refreshing Toner has a moderate anti-wrinkle rating of 4.5 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈3.0%),
 one of the most effective and well-researched anti-wrinkle ingredients.
 
Among others, Cell:Monde Nucleic Acid Refreshing Toner also contains some ingredients marketed as effective in reducing wrinkles, specifically Adenosine, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, and Beta-Glucan. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Cell:Monde Nucleic Acid Refreshing Toner is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Cell:Monde Nucleic Acid Refreshing Toner is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈3.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
70
Water
6
Glycereth-26
4
Dipropylene Glycol
3
Niacinamide
2
1,2-Hexanediol
1.5
Sodium DNA
1.3
Hydroxyethyl Urea
1
Helichrysum Italicum Flower Water
0.3
Butylene Glycol
0.3
PEG-60
0.3
Hydrogenated Castor Oil
0.3
Allantoin
0.3
Dipotassium Glycyrrhizate
0.3
Saccharomyces Cerevisiae Extract
0.3
Glycerin
0.3
Adenosine
0.3
Ocimum Basilicum (Basil) Flower/Leaf/Stem Extract
0.3
Salvia Hispanica Seed Extract
0.3
Avena Sativa (Oat) Kernel Extract
0.3
Hyaluronic Acid
0.3
Sodium Hyaluronate
0.3
Bifida Ferment Lysate
0.3
Centella Asiatica Extract
0.3
Biosaccharide Gum-1
0.3
Scutellaria Baicalensis Root Extract
0.3
Polygonum Cuspidatum Root Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Chamomilla Recutita (Matricaria) Flower Extract
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Beta-Glucan
0.3
Ethylhexylglycerin
0.3
Fragrance
0.3
Disodium EDTA
0.3
Phenoxyethanol
0.3
Benzyl Alcohol
0.3
Potassium Sorbate
0.3
Dehydroacetic Acid
Est. %
Water
Function:
Origin:
Glycereth-26
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Sodium DNA
Function:
Origin:
Hydroxyethyl Urea
Function:
Origin:
Helichrysum Italicum Flower Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
PEG-60
Function:
Origin:
Hydrogenated Castor Oil
Function:
Origin:
Allantoin
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Saccharomyces Cerevisiae Extract
Function:
Origin:
Glycerin
Function:
Origin:
Adenosine
Function:
Origin:
Ocimum Basilicum (Basil) Flower/Leaf/Stem Extract
Function:
Origin:
Salvia Hispanica Seed Extract
Function:
Origin:
Avena Sativa (Oat) Kernel Extract
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Bifida Ferment Lysate
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Biosaccharide Gum-1
Function:
Origin:
Scutellaria Baicalensis Root Extract
Function:
Origin:
Polygonum Cuspidatum Root Extract
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Extract
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Rosmarinus Officinalis (Rosemary) Leaf Extract
Function:
Origin:
Beta-Glucan
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:
Disodium EDTA
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Benzyl Alcohol
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Dehydroacetic Acid
Function:
Origin:

Ratings

All humectants
14.8
6
3
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 14.8 10
10.0
6
3
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
3
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 14.8 10
10
All humectants
14.8
6
3
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
4.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.6 3 Rich in antioxidants
All antioxidants
6.6
Niacinamide
3
Salvia Hispanica Seed Extract
0.3
Avena Sativa (Oat) Kernel Extract
0.3
Hyaluronic Acid
0.3
Sodium Hyaluronate
0.3
Centella Asiatica Extract
0.3
Scutellaria Baicalensis Root Extract
0.3
Polygonum Cuspidatum Root Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Chamomilla Recutita (Matricaria) Flower Extract
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Beta-Glucan
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 6.9 5 Rich in soothing
All soothing
6.9
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycereth-26
Est. %6
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Dipropylene Glycol
Est. %4
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

1,2-Hexanediol
Est. %2
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Sodium DNA
Est. %1.5
Function
Origin
Sodium DNADescription is coming soon
Hydroxyethyl Urea
Est. %1.3
Function
Origin
Hydroxyethyl UreaHydroxyethyl urea is a synthetic derivative of regular urea (read about it here). This ingredient, similarly to urea, is humectant moisturizing and helps to retain more water to the skin’s surface, leaving it more moisturized. There aren't any studies that analyze the effects of this ingredient in great detail.
Helichrysum Italicum Flower Water
Est. %1
Function
Origin
Helichrysum Italicum Flower WaterDescription is coming soon
Butylene Glycol
Est. %0.3
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
PEG-60
Est. %0.3
Function
Origin
PEG-60Description is coming soon
Hydrogenated Castor Oil
Est. %0.3
Function
Origin
Hydrogenated Castor OilA processed, butter-like castor oil. It is solely comprised of occlusive moisturizing and emollient saturated fatty acids and is best suited for dry skin. It can also act as a thickener and emulsifier.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Saccharomyces Cerevisiae Extract
Est. %0.3
Function
Origin
Saccharomyces Cerevisiae ExtractA fungi ingredient made from baker's yeast. It is moisturizing and contains various beneficial compounds that support skin health. Among these is beta-glucan, the praised wound healing polysaccharide.
Glycerin
Est. %0.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Ocimum Basilicum (Basil) Flower/Leaf/Stem Extract
Est. %0.3
Function
Origin
Ocimum Basilicum (Basil) Flower/Leaf/Stem ExtractDescription is coming soon
Salvia Hispanica Seed Extract
Est. %0.3
Function
Origin
Salvia Hispanica Seed ExtractAn extract from Chia seeds that contains emollient seed oil and humectant moisturizing amino acids and polysaccharides. The latter forms water-binding mucilage. Organic acids and flavonoids have antioxidant properties.
Avena Sativa (Oat) Kernel Extract
Est. %0.3
Function
Origin
Avena Sativa (Oat) Kernel ExtractA beneficial extract obtained from Oat groats popular in products aimed at eczema-prone skin. It contains skin healing beta-glucan, anti-inflammatory phenolic compounds, antioxidant flavonoids, various lipids, proteins, and moisturizing amino acids.
Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Bifida Ferment Lysate
Est. %0.3
Function
Origin
Bifida Ferment LysateA mixture of probiotic bacteria. According to the patent holder, it contains enzymes that are able to repair damaged DNA in skin cells. A single study confirms that it is able to reduce skin sensitivity.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Biosaccharide Gum-1
Est. %0.3
Function
Origin
Biosaccharide Gum-1A polysaccharide with humectant moisturizing and soothing properties.
Scutellaria Baicalensis Root Extract
Est. %0.3
Function
Origin
Scutellaria Baicalensis Root ExtractA powerful antioxidant, soothing, and astringent extract derived from the roots of Baikal/Chinese skullcap. It contains various unique flavonoids that are believed to soothe irritated and inflamed skin and protect from UV-induced oxidative damage.
Polygonum Cuspidatum Root Extract
Est. %0.3
Function
Origin
Polygonum Cuspidatum Root ExtractAn extract from the roots of the Japanese knotweed, a plant from East Asia that has spread around the world as an invasive plant. It contains various antioxidant, anti-inflammatory, and potentially anti-pigment (more tests are necessary) phytochemicals.
Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root ExtractAn extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
Camellia Sinensis Leaf ExtractAn antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Chamomilla Recutita (Matricaria) Flower Extract
Est. %0.3
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
Rosmarinus Officinalis (Rosemary) Leaf ExtractA soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Benzyl Alcohol
Est. %0.3
Function
Origin
Benzyl AlcoholA multifunctional ingredient that is supplied as a clear, colorless liquid. Its main function is as a flavoring agent and fragrance. It also acts as a broad-spectrum preservative, solvent, and viscosity-controlling agent that thins the product.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Dehydroacetic Acid
Est. %0.3
Function
Origin
Dehydroacetic AcidA globally approved preservative ingredient. It is a powerful fungicide and a moderate bactericide, which makes it a broad-spectrum preservative. Because it is mildly effective against bacteria, it is often paired with stronger bactericides.