SkinMedica Rejuvenative Moisturizer

SkinMedica Rejuvenative Moisturizer
7.0
/ 10
Moisturizing
6.5 Humectancy icon Humectancy
7.4 Occlusivity icon Occlusivity
2Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does SkinMedica Rejuvenative Moisturizer work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using SkinMedica Rejuvenative Moisturizer:

  • Significant moisturizing. It has a moisturizing rating of 7.0 out of 10.
  • Some anti-wrinkle efficacy: SkinMedica Rejuvenative Moisturizer has an anti-wrinkle rating of 2.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Well-suited moisturizer for normal to dry skin

According to CreamScan analysis, SkinMedica Rejuvenative Moisturizer is highly moisturizing, with a moisturizing rating of 7.0 out of 10.

Is it more humectant or occlusive? This product has relatively comparable levels of humectancy and occlusivity: a high humectancy of 6.5 out of 10, primarily due to the substantial concentration of Diglycerin (est. ≈4.0%), and a high occlusivity of 7.4 out of 10, mainly due to the significant content of Caprylic/Capric Triglyceride (est. ≈9.0%) and Isostearyl Behenate (est. ≈3.0%).

This type of moisturizer is well-suited for people with normal skin who want significant hydration in a rich yet not overly thick formula. It combines a significant amount of humectants and occlusive ingredients to provide effective dual-action moisturizing.

The product’s occlusive profile suggests a texture that is rich and creamy but not overly thick, offering the potential to absorb into the skin without leaving a greasy afterfeel in most cases.

This product may also be a good choice for people with dry (but not very dry) skin for daily hydration, as it strikes a balance between significant moisturizing potential and a texture that is not too thick.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, SkinMedica Rejuvenative Moisturizer has a slight anti-wrinkle rating of 2.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Ascorbyl Tetraisopalmitate (est. ≈1.5%), 
 the only derivative of ascorbic acid with solid evidence of anti-wrinkle efficacy. A single clinical study involving 23 participants (Mariko et al.) demonstrated that a cream with 1% ATIP reduced the average depth of periorbital wrinkles by 6% after 8 weeks of use, compared to a vehicle (the same formulation without ATIP).
 
Among others, SkinMedica Rejuvenative Moisturizer also contains Retinyl Palmitate, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Retinyl Palmitate provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that SkinMedica Rejuvenative Moisturizer is rich (> 3%) in antioxidants, specifically Tocopheryl Acetate (est. ≈6.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

.

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Diglycerin
Function:
Origin:
Isostearyl Behenate
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Ascorbyl Tetraisopalmitate
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Panthenol
Function:
Origin:
Phytosterols
Function:
Origin:
Tocopherol
Function:
Origin:
Tocotrienols
Function:
Origin:
Squalene
Function:
Origin:
Oryza Sativa (Rice) Bran Wax
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Algae Extract
Function:
Origin:
Bisabolol
Function:
Origin:
Ginkgo Biloba Leaf Extract
Function:
Origin:
Avena Sativa (Oat) Kernel Extract
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Stearyl Glycyrrhetinate
Function:
Origin:
Retinyl Palmitate
Function:
Origin:
Glycerin
Function:
Origin:
Glyceryl Polyacrylate
Function:
Origin:
Dimethicone
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Ceteareth-20
Function:
Origin:
Caprylyl Methicone
Function:
Origin:
Carbomer
Function:
Origin:
Tromethamine
Function:
Origin:
Disodium EDTA
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
6.5
4
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
14.8
9.0
3.0
1.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
7.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 6.5 10
6.5
4
1
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 14.8 20
7.4
9.0
3.0
1.3
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
7.0
Ingredient Est. % Benchmark Humectancy
4
1
0.3
0.3
0.3
0.3
0.3
All humectants 6.5 10
6.5
All humectants
6.5
4
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
9
3
1.3
0.3
0.3
0.3
0.3
0.3
All occlusives 14.8 20
7.4
All occlusives
14.8
9.0
3.0
1.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2 /10 1 1.5 2
n/a
- 0.3 -
Total
2
Ascorbyl Tetraisopalmitate
2
Ingredient anti-wrinkle power
2 /10
when present at, %
1
in this formula, est. %
1.5
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2
Ingredient Est. % Benchmark
Rich in Antioxidants
6
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 9.9 3 Rich in antioxidants
All antioxidants
9.9
Tocopheryl Acetate
6
Ascorbyl Tetraisopalmitate
1.5
Phytosterols
0.3
Tocopherol
0.3
Squalene
0.3
Aloe Barbadensis Leaf Juice
0.3
Algae Extract
0.3
Ginkgo Biloba Leaf Extract
0.3
Avena Sativa (Oat) Kernel Extract
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1
0.3
0.3
0.3
0.3
0.3
All soothing 2.5 5 No
All soothing
2.5
1
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Caprylic/Capric Triglyceride
Est. %9
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Tocopheryl Acetate
Est. %6
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Diglycerin
Est. %4
Function
Origin
DiglycerinA powerful humectant that collects moisture, making skin feel hydrated and supple. Diglycerin is less sticky and a stronger humectant, but slower absorbing than standard glycerin.
Isostearyl Behenate
Est. %3
Function
Origin
Isostearyl Behenate
Glyceryl Stearate
Est. %2.5
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %2
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Ascorbyl Tetraisopalmitate
Est. %1.5
Function
Origin
Ascorbyl Tetraisopalmitate

Ascorbyl Tetraisopalmitate (ATIP) is an oil-soluble derivative of ascorbic acid, or vitamin C. It is more stable than ascorbic acid, with studies supporting its collagen-boosting and anti-pigment effects.

Butyrospermum Parkii (Shea) Butter
Est. %1.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Panthenol
Est. %1
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Phytosterols
Est. %0.3
Function
Origin
PhytosterolsA plant-based version of cholesterol that is used for its emollient properties in skincare. The richest sources of phytosterols are corn, rapeseed, and wheat germ oil.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Tocotrienols
Est. %0.3
Function
Origin
Tocotrienols
Squalene
Est. %0.3
Function
Origin
SqualeneOne of the main ingredients in the skin’s sebum. It helps to rebuild the natural oily film on the skin’s surface and to prevent transdermal water loss. Squalene is listed among common comedogenic ingredients by acne.org.
Oryza Sativa (Rice) Bran Wax
Est. %0.3
Function
Origin
Oryza Sativa (Rice) Bran WaxA solid, strongly emollient, and occlusive moisturizing wax obtained from rice bran oil. It is also used as a formula helper.
Aloe Barbadensis Leaf Juice
Est. %0.3
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Algae Extract
Est. %0.3
Function
Origin
Algae ExtractThe name describes any extract made from any kind of algae. Algae extracts are moisturizing humectants – the gelatin-like polysaccharides bind and retain water, thereby hydrating the skin. Algae is a rich source of emollient and antioxidant compounds.
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Ginkgo Biloba Leaf Extract
Est. %0.3
Function
Origin
Ginkgo Biloba Leaf ExtractAn antioxidant, astringent and soothing extract derived from Ginkgo biloba tree leaves, a rare Chinese tree that is endangered in the wild, but grown nowadays as a decorative tree in parks. When taken orally, the extract can improve memory and brain function.
Avena Sativa (Oat) Kernel Extract
Est. %0.3
Function
Origin
Avena Sativa (Oat) Kernel ExtractA beneficial extract obtained from Oat groats popular in products aimed at eczema-prone skin. It contains skin healing beta-glucan, anti-inflammatory phenolic compounds, antioxidant flavonoids, various lipids, proteins, and moisturizing amino acids.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Stearyl Glycyrrhetinate
Est. %0.3
Function
Origin
Stearyl GlycyrrhetinateA plant compound obtained from licorice root. It is a powerful soothing ingredient that acts similar to steroid hormones and helps to treat inflamed and irritated skin.
Retinyl Palmitate
Est. %0.3
Function
Origin
Retinyl PalmitateAn esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Glycerin
Est. %0.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Glyceryl Polyacrylate
Est. %0.3
Function
Origin
Glyceryl PolyacrylateA synthetic thickening polymer that can be used in a variety of product types. This polymer can feel lightweight but can also stand up to heavier ingredients in products like body butters.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Ceteareth-20
Est. %0.3
Function
Origin
Ceteareth-20A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Caprylyl Methicone
Est. %0.3
Function
Origin
Caprylyl MethiconeA liquid silicone with occlusive moisturizing properties. Being compatible with natural oils is a challenge for most silicones, but caprylyl methicone plays well with all types of oils.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.