Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer

Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer
8.3
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
6.6 Occlusivity icon Occlusivity
4.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer:

  • Intense moisturizing. It has a moisturizing rating of 8.3 out of 10.
  • Considerable anti-wrinkle efficacy: Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer has an anti-wrinkle rating of 4.5 out of 10, indicating a moderate ability to reduce wrinkles.
  • Antioxidant protection.

Perfect moisturizer for normal to dry skin

According to CreamScan analysis, Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer is intensely moisturizing, with a moisturizing rating of 8.3 out of 10.

Is it more humectant or occlusive? Rather humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%) and Pentylene Glycol (est. ≈4.0%), and a high occlusivity of 6.6 out of 10, mainly due to the significant content of Dimethicone (est. ≈9.0%) and Caprylic/Capric Triglyceride (est. ≈2.0%).

This type of moisturizer is ideal for people with normal skin who want intense hydration in a rich yet not overly thick formula. It combines a high concentration of humectants with a significant amount of occlusive ingredients to provide effective dual-action moisturizing.

The product’s occlusive profile suggests a texture that is rich and creamy but not overly thick, offering the potential to absorb into the skin without leaving a greasy afterfeel in most cases.

This product may also be a good choice for people with dry (but not very dry) skin for daily hydration, as it strikes a balance between significant moisturizing potential and a texture that is not too thick.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Considerable anti-wrinkle efficacy

According to CreamScan analysis, Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer has a moderate anti-wrinkle rating of 4.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈3.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer also contains some ingredients marketed often as effective in reducing wrinkles, specifically Tetrahexyldecyl Ascorbate, Dimethyl MEA, and Copper Gluconate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Perricone MD High Potency Classics Hyaluronic Intensive Moisturizer is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Dimethicone
Function:
Origin:
Glycerin
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
Butylene Glycol
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Ammonium Acryloyldimethyltaurate/VP Copolymer
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Squalane
Function:
Origin:
Sodium Hyaluronate Crosspolymer
Function:
Origin:
Benzyl Alcohol
Function:
Origin:
Urea
Function:
Origin:
Tetrahexyldecyl Ascorbate
Function:
Origin:
Bisabolol
Function:
Origin:
Dimethyl MEA
Function:
Origin:
Styrene/Acrylates Copolymer
Function:
Origin:
Dimethicone/Vinyl Dimethicone Crosspolymer
Function:
Origin:
Carbomer
Function:
Origin:
Sodium Polyacrylate
Function:
Origin:
Phosphatidylcholine
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Citric Acid
Function:
Origin:
Allantoin
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Polysilicone-11
Function:
Origin:
Triacetin
Function:
Origin:
Xanthan Gum
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Sodium Chloride
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Rosmarinus Officinalis (Rosemary) Leaf Extract
Function:
Origin:
Sodium Lactate
Function:
Origin:
Lactic Acid
Function:
Origin:
Serine
Function:
Origin:
Sorbitol
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Docosahexaenoic Acid
Function:
Origin:
Magnesium Aspartate
Function:
Origin:
Zinc Gluconate
Function:
Origin:
Copper Gluconate
Function:
Origin:

Ratings

All humectants
18.2
6
4
3
2.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
13.3
9.0
2.0
1.3
1.0
Benchmark
20
Moisturizing rating
8.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 18.2 10
10.0
6
4
3
2.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 13.3 20
6.6
9.0
2.0
1.3
1.0
Moisturizing rating
8.3
Ingredient Est. % Benchmark Humectancy
6
4
3
2.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 18.2 10
10
All humectants
18.2
6
4
3
2.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
9
2
1.3
1
All occlusives 13.3 20
6.6
All occlusives
13.3
9.0
2.0
1.3
1.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
4.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Tetrahexyldecyl Ascorbate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dimethyl MEA
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Gluconate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
0.3
0.3
0.3
All antioxidants 4.5 3 Rich in antioxidants
All antioxidants
4.5
Niacinamide
3
Tetrahexyldecyl Ascorbate
0.3
Hyaluronic Acid
0.3
Tocopheryl Acetate
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
0.3
0.3
0.3
All soothing 4.5 5 No
All soothing
4.5
3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Dimethicone
Est. %9
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Pentylene Glycol
Est. %4
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Butylene Glycol
Est. %2.5
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Caprylic/Capric Triglyceride
Est. %2
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %1.5
Function
Origin
Ammonium Acryloyldimethyltaurate/VP CopolymerA polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.
Butyrospermum Parkii (Shea) Butter
Est. %1.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Squalane
Est. %1
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Sodium Hyaluronate Crosspolymer
Est. %0.3
Function
Origin
Sodium Hyaluronate CrosspolymerA modified version of regular hyaluronic acid. It attracts large volumes of water, thereby making it an effective humectant moisturizing ingredient.
Benzyl Alcohol
Est. %0.3
Function
Origin
Benzyl Alcohol

A multifunctional ingredient that is supplied as a clear, colorless liquid. Its main function is as a flavoring agent and fragrance. It also acts as a broad-spectrum preservative, solvent, and viscosity-controlling agent that thins the product.

Urea
Est. %0.3
Function
Origin
UreaUrea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Tetrahexyldecyl Ascorbate
Est. %0.3
Function
Origin
Tetrahexyldecyl AscorbateA lipid-soluble form of vitamin C that is more stable and less irritating than ascorbic acid. According to a recent clinical study, THDA has all the capabilities of regular vitamin C, including anti-wrinkle and anti-pigment activity.
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Dimethyl MEA
Est. %0.3
Function
Origin
Dimethyl MEA

Dimethyl MEA, also known as DMAE, or deanol, is a colorless liquid with a fishy smell. It can also be supplied as a crystalline white powder. Some studies suggest it may have some effects on skin firmness. Additionally, DMAE is used to regulate pH balance. It has the potential to be toxic.

Styrene/Acrylates Copolymer
Est. %0.3
Function
Origin
Styrene/Acrylates Copolymer
Dimethicone/Vinyl Dimethicone Crosspolymer
Est. %0.3
Function
Origin
Dimethicone/Vinyl Dimethicone CrosspolymerThis ingredient can refer to several kinds of dimethicone crosspolymers. Like other silicones, it makes products feel slippery and non-greasy but can also increase the thickness or improve the water-resistance of a formula.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Sodium Polyacrylate
Est. %0.3
Function
Origin
Sodium PolyacrylateThis white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Phosphatidylcholine
Est. %0.3
Function
Origin
PhosphatidylcholineA special emulsifying lipid used to create delivery spheres called liposomes.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Polysilicone-11
Est. %0.3
Function
Origin
Polysilicone-11A synthetic rubber-like substance of the silicone family that has no color or distinct scent. These are large molecules that cannot penetrate the skin but instead create a thin silky film on the skin's surface.
Triacetin
Est. %0.3
Function
Origin
Triacetin
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Sodium Chloride
Est. %0.3
Function
Origin
Sodium Chloride

You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
Rosmarinus Officinalis (Rosemary) Leaf ExtractA soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Sodium Lactate
Est. %0.3
Function
Origin
Sodium LactateA sodium salt of lactic acid. Its main function is as a humectant but it can also serve as a pH adjuster. Additionally, sodium lactate can also be used as a chemical exfoliant due to its close chemical relation to lactic acid.
Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Sorbitol
Est. %0.3
Function
Origin
SorbitolA sweet-tasting alcohol derived from glucose. Aside from its sweet taste (for which it is used as a very common sweetener), Sorbitol is also very good at retaining water and is used in skincare as a humectant.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Docosahexaenoic Acid
Est. %0.3
Function
Origin
Docosahexaenoic Acid
Magnesium Aspartate
Est. %0.3
Function
Origin
Magnesium AspartateA humectant salt of aspartic acid, a common amino acid found in the body. According to the manufacturer, magnesium aspartate in skincare products supports the supply of magnesium to skin cells.
Zinc Gluconate
Est. %0.3
Function
Origin
Zinc GluconateOne of the most commonly used ingredients in anti-acne products. It is an organic salt of zinc that helps to combat microbial infections, soothes and heals inflamed pimples, and regulates hormones in the skin.
Copper Gluconate
Est. %0.3
Function
Origin
Copper GluconateAn organic salt of copper that can aid in the wound healing process. The manufacturer claims it also has soothing and anti-inflammatory properties, although this has yet to be confirmed. Copper gluconate is also a perspective anti-wrinkle ingredient.