Osmosis Beauty Renew Advanced Retinal Serum Review

Osmosis Beauty Renew Advanced Retinal Serum
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
10Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Osmosis Beauty Renew Advanced Retinal Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Osmosis Beauty Renew Advanced Retinal Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
✅ Potent anti-wrinkle effect with the highest possible efficacy rating. With an anti-wrinkle rating of 10 out of 10, Osmosis Beauty Renew Advanced Retinal Serum is highly potent in reducing wrinkles.
✅ Soothing: Osmosis Beauty Renew Advanced Retinal Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Osmosis Beauty Renew Advanced Retinal Serum

 
These are the key benefits you can expect from using Osmosis Beauty Renew Advanced Retinal Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Osmosis Beauty Renew Advanced Retinal Serum is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Niacinamide (est. ≈5.0%), Pentylene Glycol (est. ≈3.0%) and Glycerin (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣🟣 Potent Anti-Wrinkle Efficacy

According to CreamScan analysis, Osmosis Beauty Renew Advanced Retinal Serum has a maximum anti-wrinkle rating of 10 out of 10.

It contains 3 active ingredients with proven anti-wrinkle efficacy:

1️⃣ Niacinamide (est. ≈5.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
2️⃣ Retinal (est. ≈0.05%),
 also known as retinaldehyde, is a potent retinoid with anti-wrinkle efficacy confirmed by a single clinical study involving 125 participants (Creidi et al.). This study demonstrated that a cream containing 0.05% retinal reduced the average wrinkle depth by 8% after 18 weeks of use, compared to a vehicle (the same formulation without retinal).
 
3️⃣ Asiaticoside (est. ≈1.3%),
 derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 27 participants (Lee et al.). This study demonstrated that a cream containing 0.1% asiaticoside reduced the average wrinkle depth by 8% after 12 weeks of use, compared to a vehicle (the same formulation without asiaticoside).
 
Among others, Osmosis Beauty Renew Advanced Retinal Serum also contains some ingredients marketed often as effective in reducing wrinkles, specifically Caprooyl Tetrapeptide-3, Palmitoyl Tripeptide-38, and Beta-Glucan. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Osmosis Beauty Renew Advanced Retinal Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈5.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Osmosis Beauty Renew Advanced Retinal Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈5.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Osmosis Beauty Renew Advanced Retinal Serum

 
CreamScan AI identified a few things to consider before adding Osmosis Beauty Renew Advanced Retinal Serum to your skincare routine:
 

⚠️ If It’s an Exfoliator, It May Increase Skin Photosensitivity Due to Lactic Acid

This product contains lactic acid, a popular AHA known for its ability to gently exfoliate and brighten the skin. It works by removing dead skin cells, revealing new, more delicate skin that is more vulnerable to sun damage.

In smaller quantities, lactic acid is often used as a pH adjuster and may not significantly contribute to exfoliation. However, at higher concentrations, it functions as an effective exfoliant with benefits and risks similar to other AHAs. Products with AHAs, including lactic acid, may increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

If this product is designed for exfoliation, applying a broad-spectrum sunscreen with at least SPF 30 daily is essential to protect your skin. Always check the label or the manufacturer’s website for specific usage instructions.

Pros & Cons of Osmosis Beauty Renew Advanced Retinal Serum

 
Here’s an overview of the pros and cons of Osmosis Beauty Renew Advanced Retinal Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers potent anti-wrinkle efficacy with the highest possible rating of 10 out of 10 thanks to ingredients like Niacinamide and Retinal, among others
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients, specifically Niacinamide
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Osmosis Beauty Renew Advanced Retinal Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Osmosis Beauty Renew Advanced Retinal Serum
 is highly effective in treating wrinkles, featuring ingredients with solid, robust evidence of anti-wrinkle efficacy, in concentrations that may deliver a significant anti-wrinkle effect.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, Osmosis Beauty Renew Advanced Retinal Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
That said, there are some things about Osmosis Beauty Renew Advanced Retinal Serum worth noting.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
75
5
4
3
2
1.5
1.3
1
0.3
0.3
0.05
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Niacinamide
Function:
Origin:
Phosphatidylcholine
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Cyclodextrin
Function:
Origin:
Asiaticoside
Function:
Origin:
Chlorella Vulgaris Extract
Function:
Origin:
Caprooyl Tetrapeptide-3
Function:
Origin:
Epilobium Angustifolium Flower/Leaf/Stem Extract
Function:
Origin:
Retinal
Function:
Origin:
Palmitoyl Tripeptide-38
Function:
Origin:
Lactic Acid
Function:
Origin:
Dimethyl Sulfone
Function:
Origin:
Fulvic Acid
Function:
Origin:
Hydroxyproline
Function:
Origin:
Beta-Glucan
Function:
Origin:
Thioctic Acid
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Lavandula Angustifolia (Lavender) Oil
Function:
Origin:
Rubus Chamaemorus Seed Oil
Function:
Origin:
Santalum Austrocaledonicum Wood Oil
Function:
Origin:
Pogostemon Cablin Oil
Function:
Origin:
Lonicera Caprifolium (Honeysuckle) Flower Extract
Function:
Origin:
Lonicera Japonica (Honeysuckle) Flower Extract
Function:
Origin:
Dextran
Function:
Origin:
Xanthan Gum
Function:
Origin:
Alcohol Denat.
Function:
Origin:
Hydroxypropyl Cyclodextrin
Function:
Origin:
Benzyl Alcohol
Function:
Origin:

Ratings

All humectants
10.9
5
3
2
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.9 10
10.0
5
3
2
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
5
3
2
0.3
0.3
0.3
All humectants 10.9 10
10
All humectants
10.9
5
3
2
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 5 6
5 /10 0.05 0.05 5
3 /10 0.1 1.3 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
10
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
5
Retinal
5
Ingredient anti-wrinkle power
5 /10
when present at, %
0.05
in this formula, est. %
0.05
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
1.3
Caprooyl Tetrapeptide-3
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-38
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
10
Ingredient Est. % Benchmark
Rich in Antioxidants
5
1.3
1
0.3
0.3
0.3
0.3
0.3
All antioxidants 8.8 3 Rich in antioxidants
All antioxidants
8.8
Niacinamide
5
Asiaticoside
1.3
Chlorella Vulgaris Extract
1
Epilobium Angustifolium Flower/Leaf/Stem Extract
0.3
Beta-Glucan
0.3
Thioctic Acid
0.3
Sodium Hyaluronate
0.3
Lonicera Japonica (Honeysuckle) Flower Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
5
0.3
0.3
All soothing 5.6 5 Rich in soothing
All soothing
5.6
5
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Niacinamide
Est. %5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Phosphatidylcholine
Est. %4
Function
Origin
PhosphatidylcholineA special emulsifying lipid used to create delivery spheres called liposomes.
Pentylene Glycol
Est. %3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Glycerin
Est. %2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Cyclodextrin
Est. %1.5
Function
Origin
CyclodextrinA naturally derived ingredient with the ability to absorb other compounds and remove harmful metal ions from water.
Asiaticoside
Est. %1.3
Function
Origin
Asiaticoside

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Chlorella Vulgaris Extract
Est. %1
Function
Origin
Chlorella Vulgaris ExtractA dried mass of tiny, single-cell green algae. It is widely used as a food source or dietary supplement since it is rich in proteins, amino acids, minerals, and vitamins. This dark green extract is used as an antioxidant agent in skincare.
Caprooyl Tetrapeptide-3
Est. %0.3
Function
Origin
Caprooyl Tetrapeptide-3

A synthetically made peptide that was designed to emulate the skin growth factor. It is said to boost the production of the skin's structural elements and the dermo-epidermal junction, although this has not been independently tested.

Epilobium Angustifolium Flower/Leaf/Stem Extract
Est. %0.3
Function
Origin
Epilobium Angustifolium Flower/Leaf/Stem ExtractAn extract from a plant known in North America as Fireweed and in Europe as Willowherb. It is commonly used in traditional herbal medicine. Due to its abundant content of tannins and flavonoids, it has great astringent and antioxidant properties.
Retinal
Est. %0.05
Function
Origin
Retinal

A potent ingredient of the retinoid group with confirmed anti-wrinkle capabilities.

Palmitoyl Tripeptide-38
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-38

A small synthetic peptide that increases the production of collagen, fibronectin, and hyaluronic acid in the skin. It has also been shown to reduce wrinkles in combination with other anti-aging ingredients.

Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Dimethyl Sulfone
Est. %0.3
Function
Origin
Dimethyl Sulfone
Fulvic Acid
Est. %0.3
Function
Origin
Fulvic Acid
Hydroxyproline
Est. %0.3
Function
Origin
HydroxyprolineAn amino acid that may promote collagen synthesis.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Thioctic Acid
Est. %0.3
Function
Origin
Thioctic Acid
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Lavandula Angustifolia (Lavender) Oil
Est. %0.3
Function
Origin
Lavandula Angustifolia (Lavender) OilAn essential oil derived from common, or true, lavender. It is used in skincare for its lovely, calming scent. Like all essential oils, however, it may cause a contact skin allergy in more sensitive individuals.
Rubus Chamaemorus Seed Oil
Est. %0.3
Function
Origin
Rubus Chamaemorus Seed Oil
Santalum Austrocaledonicum Wood Oil
Est. %0.3
Function
Origin
Santalum Austrocaledonicum Wood Oil
Pogostemon Cablin Oil
Est. %0.3
Function
Origin
Pogostemon Cablin OilA luxurious, fragrant essential oil obtained from patchouli leaves. It contains germacrene, patchoulol, and norpatchoulenol - which are responsible for its musky, earthy, and sweet scent.
Lonicera Caprifolium (Honeysuckle) Flower Extract
Est. %0.3
Function
Origin
Lonicera Caprifolium (Honeysuckle) Flower ExtractA fragrant extract derived from the flowers of the Italian honeysuckle. It has a pleasant, sweet, floral scent. Not much is known about its compounds and their functions.
Lonicera Japonica (Honeysuckle) Flower Extract
Est. %0.3
Function
Origin
Lonicera Japonica (Honeysuckle) Flower ExtractAn extract from the white flowers of the Japanese honeysuckle. Apart from an essential oil responsible for its jasmine-like scent, the extract also contains antioxidant and anti-inflammatory iridoids, flavonoids, and phenolic acids.
Dextran
Est. %0.3
Function
Origin
DextranA naturally derived sucrose metabolite that thickens water and bulks emulsions.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Alcohol Denat.
Est. %0.3
Function
Origin
Alcohol Denat.

Denatured alcohol is ethanol that contains additives that make it unsafe to consume. It is mainly used as a solvent and an antimicrobial agent. A major drawback to alcohol denat. is that it dries out the skin.

Hydroxypropyl Cyclodextrin
Est. %0.3
Function
Origin
Hydroxypropyl CyclodextrinA white crystalline powder that can reduce odors coming from other ingredients in a product.
Benzyl Alcohol
Est. %0.3
Function
Origin
Benzyl Alcohol

A multifunctional ingredient that is supplied as a clear, colorless liquid. Its main function is as a flavoring agent and fragrance. It also acts as a broad-spectrum preservative, solvent, and viscosity-controlling agent that thins the product.