Neocutis Bio Cream Firm

Neocutis Bio Cream Firm
4.8
/ 10
Moisturizing
7.6 Humectancy icon Humectancy
1.9 Occlusivity icon Occlusivity
2.2Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does Neocutis Bio Cream Firm work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Neocutis Bio Cream Firm:

  • Moderate moisturizing. It has a moisturizing rating of 4.8 out of 10.
  • Some anti-wrinkle efficacy: Neocutis Bio Cream Firm has an anti-wrinkle rating of 2.2 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Lightweight moisturizer well-suited for oily skin and a humectant enhancement for any skincare routine

According to CreamScan analysis, Neocutis Bio Cream Firm is quite moisturizing, with a moisturizing rating of 4.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.9 out of 10 and a high humectancy of 7.6 out of 10, primarily due to the high content of Propylene Glycol (est. ≈3.0%) and Glycerin (est. ≈2.5%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It can also be a good option for people with normal skin who prefer lightweight moisturizers.

Such a humectant engancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, Neocutis Bio Cream Firm has a slight anti-wrinkle rating of 2.2 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈1.5%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Neocutis Bio Cream Firm also contains Tetrapeptide-21, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Tetrapeptide-21 provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Neocutis Bio Cream Firm is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈1.5%), Argania Spinosa Kernel Oil (est. ≈1.0%), Borago Officinalis Seed Oil (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Octyldodecanol
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Decyl Oleate
Function:
Origin:
Propylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Stearic Acid
Function:
Origin:
Niacinamide
Function:
Origin:
Ceteareth-20
Function:
Origin:
Argania Spinosa Kernel Oil
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Cutaneous Lysate
Function:
Origin:
Tetrapeptide-21
Function:
Origin:
Palmitoyl Tripeptide-1 Acetate
Function:
Origin:
Sodium Lauroyl Lactylate
Function:
Origin:
Borago Officinalis Seed Oil
Function:
Origin:
Dimethicone
Function:
Origin:
Citric Acid
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Capryloyl Carnosine
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Ceteareth-12
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Cetyl Palmitate
Function:
Origin:
Ceramide NG
Function:
Origin:
Myreth-3 Myristate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Carbomer
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Ceramide NP
Function:
Origin:
Ceramide AP
Function:
Origin:
Phytosphingosine
Function:
Origin:
Cholesterol
Function:
Origin:
Xanthan Gum
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Ceramide EOP
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
BHT
Function:
Origin:
Disodium EDTA
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
7.6
3
2.5
1.5
0.3
0.3
Benchmark
10
All occlusives
3.9
2.0
1.0
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
4.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.6 10
7.6
3
2.5
1.5
0.3
0.3
Occlusivity All occlusives 3.9 20
1.9
2.0
1.0
0.3
0.3
0.3
Moisturizing rating
4.8
Ingredient Est. % Benchmark Humectancy
3
2.5
1.5
0.3
0.3
All humectants 7.6 10
7.6
All humectants
7.6
3
2.5
1.5
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2
1
0.3
0.3
0.3
All occlusives 3.9 20
1.9
All occlusives
3.9
2.0
1.0
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1.5 2.2
n/a
- 0.3 -
Total
2.2
Niacinamide
2.2
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1.5
Tetrapeptide-21
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.2
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1
0.3
0.3
0.3
All antioxidants 3.4 3 Rich in antioxidants
All antioxidants
3.4
Niacinamide
1.5
Argania Spinosa Kernel Oil
1
Borago Officinalis Seed Oil
0.3
Tocopheryl Acetate
0.3
BHT
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.5
0.3
0.3
All soothing 2.1 5 No
All soothing
2.1
1.5
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Octyldodecanol
Est. %9
Function
Origin
OctyldodecanolAn emollient fatty alcohol that spreads easily without leaving a greasy residue on the skin. It is also used as a solvent and dispersing agent for other ingredients.
Glyceryl Stearate
Est. %6
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Decyl Oleate
Est. %4
Function
Origin
Decyl OleateA vegetable-derived or synthetically produced ester that feels velvety and makes the skin feel soft. It is non-greasy and helps reduce stickiness in formulas and improve spreadability.
Propylene Glycol
Est. %3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Glycerin
Est. %2.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Stearic Acid
Est. %2
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Niacinamide
Est. %1.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Ceteareth-20
Est. %1.3
Function
Origin
Ceteareth-20A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Argania Spinosa Kernel Oil
Est. %1
Function
Origin
Argania Spinosa Kernel OilA fatty oil from Moroccan argan tree kernels commonly used as an occlusive moisturizer and emollient. Its uniqueness comes from its compounds: vitamin E, phospholipids, phenolic compounds, and rare phytosterols with antioxidant and emollient effects.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Cutaneous Lysate
Est. %0.3
Function
Origin
Cutaneous Lysate
Tetrapeptide-21
Est. %0.3
Function
Origin
Tetrapeptide-21

A synthetically made peptide (similar to skin proteins) designed to increase the synthesis of collagen, HA, and fibronectin. It has been clinically proven to improve skin quality and elasticity, as well as the appearance of wrinkles.

Palmitoyl Tripeptide-1 Acetate
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1 Acetate
Sodium Lauroyl Lactylate
Est. %0.3
Function
Origin
Sodium Lauroyl LactylateA multifunctional ingredient that produces foamy cleansers and allows oil and water to mix.
Borago Officinalis Seed Oil
Est. %0.3
Function
Origin
Borago Officinalis Seed OilA fatty emollient and occlusive oil expressed from the seeds of borage flowers. It has a uniquely high content of a rare gamma-linolenic acid and also contains squalene, phytosterols, and vitamin E.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Capryloyl Carnosine
Est. %0.3
Function
Origin
Capryloyl Carnosine
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Ceteareth-12
Est. %0.3
Function
Origin
Ceteareth-12A waxy emulsifier that can build stable emulsions.
Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Cetyl Palmitate
Est. %0.3
Function
Origin
Cetyl PalmitateA moisturizing occlusive and emollient wax ester that consists of cetyl alcohol and palmitic acid. In nature, cetyl palmitate is found, and was first identified, in spermaceti, a waxy substance from inside the skull of the sperm whale.
Ceramide NG
Est. %0.3
Function
Origin
Ceramide NGA lipid that is mainly found on scalp skin and that helps with the barrier repair. It is one of the less popular ceramides and is usually used in combination with other ceramides for better barrier repair properties.
Myreth-3 Myristate
Est. %0.3
Function
Origin
Myreth-3 Myristate
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Ceramide AP
Est. %0.3
Function
Origin
Ceramide APPreviously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Phytosphingosine
Est. %0.3
Function
Origin
PhytosphingosineA key component of ceramides NP, AP, and EOP. It has barrier repair properties and stimulates the production of the skin’s Natural Moisturizing Factor. Phytosphingosine has strong antimicrobial and anti-inflammatory activity, which can be used to treat acne.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Ceramide EOP
Est. %0.3
Function
Origin
Ceramide EOP

Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.

Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

BHT
Est. %0.3
Function
Origin
BHTAn antioxidant ingredient that naturally occurs in green algae and some bacteria or fungi but, for commercial use, is created synthetically. BHT is also used occasionally as a fragrance, where it presents a sweet, camphor-like odor.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.