Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum

Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum
6.8
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
3.6 Occlusivity icon Occlusivity
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Does Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum:

  • Significant moisturizing. It has a moisturizing rating of 6.8 out of 10.
  • Soothing: Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Lightweight moisturizer perfect for oily to normal skin

According to CreamScan analysis, Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum is highly moisturizing, with a moisturizing rating of 6.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Aloe Barbadensis Leaf Juice (est. ≈70.0%) and Glycerin (est. ≈6.0%), and a moderate occlusivity of 3.6 out of 10, mainly due to the high content of Simmondsia Chinensis (Jojoba) Seed Oil (est. ≈4.0%).

This type of moisturizer is ideal for people with oily skin who want maximum hydration in a relatively lightweight, non-greasy formula. It combines a significant amount of humectants with a limited amount of occlusive ingredients to boost moisturizing efficacy without feeling too heavy.

This product may also be a good choice for people with normal skin who prefer fast-absorbing textures, as it balances significant moisturizing potential with a relatively lightweight texture.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Questionable anti-wrinkle efficacy

According to CreamScan analysis, Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum has a zero anti-wrinkle rating.

It contains some ingredients often marketed as effective in reducing wrinkles, specifically Ubiquinone, Magnesium Ascorbyl Phosphate, Malus Domestica Fruit Cell Culture Extract, and Acetyl Hexapeptide-8. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum is rich (> 3%) in antioxidants, specifically Aloe Barbadensis Leaf Juice (est. ≈70.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing and calming potential

Based on the ingredient list analysis, Juice Beauty STEM CELLULAR Anti-Wrinkle Retinol Overnight Serum is rich (> 5%) in soothing ingredients, particularly Aloe Barbadensis Leaf Juice (est. ≈70.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

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Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Aloe Barbadensis Leaf Juice
Function:
Origin:
Glycerin
Function:
Origin:
Simmondsia Chinensis (Jojoba) Seed Oil
Function:
Origin:
Coconut Alkanes
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Stearic Acid
Function:
Origin:
Pyrus Malus (Apple) Juice
Function:
Origin:
Vitis Vinifera (Grape) Juice
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Oil
Function:
Origin:
Glyceryl Stearate Citrate
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Oenothera Biennis Leaf Cell Extract
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
Gossypium Herbaceum (Cotton) Seed Oil
Function:
Origin:
Linum Usitatissimum (Linseed) Seed Oil
Function:
Origin:
Bidens Pilosa Extract
Function:
Origin:
Astrocaryum Murumuru Seed Butter
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Ubiquinone
Function:
Origin:
Tocopherol
Function:
Origin:
Panthenol
Function:
Origin:
Magnesium Ascorbyl Phosphate
Function:
Origin:
Coco-Caprylate/Caprate
Function:
Origin:
Malus Domestica Fruit Cell Culture Extract
Function:
Origin:
Vitis Vinifera (Grape) Fruit Cell Extract
Function:
Origin:
Citrus Limon (Lemon) Leaf Extract
Function:
Origin:
Camellia Sinensis Extract
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Xanthan Gum
Function:
Origin:
Mica
Function:
Origin:
Allantoin
Function:
Origin:
Titanium Dioxide (CI 77891)
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Diheptyl Succinate
Function:
Origin:
Polyglyceryl-6 Distearate
Function:
Origin:
Capryloyl Glycerin/Sebacic Acid Copolymer
Function:
Origin:
Thioctic Acid
Function:
Origin:
Litsea Cubeba Fruit Oil
Function:
Origin:
Cinnamomum Camphora (Camphor) Bark Oil
Function:
Origin:

Ratings

All humectants
78.1
70
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
7.3
4.0
1.5
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
6.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 78.1 10
10.0
70
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 7.3 20
3.6
4.0
1.5
0.3
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
6.8
Ingredient Est. % Benchmark Humectancy
70
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 78.1 10
10
All humectants
78.1
70
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
1.5
0.3
0.3
0.3
0.3
0.3
0.3
All occlusives 7.3 20
3.6
All occlusives
7.3
4.0
1.5
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Magnesium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Malus Domestica Fruit Cell Culture Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
70
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 73.7 3 Rich in antioxidants
All antioxidants
73.7
Aloe Barbadensis Leaf Juice
70
Vitis Vinifera (Grape) Juice
1
Sodium Hyaluronate
0.3
Ubiquinone
0.3
Tocopherol
0.3
Magnesium Ascorbyl Phosphate
0.3
Malus Domestica Fruit Cell Culture Extract
0.3
Vitis Vinifera (Grape) Fruit Cell Extract
0.3
Citrus Limon (Lemon) Leaf Extract
0.3
Camellia Sinensis Extract
0.3
Thioctic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
70
0.3
0.3
0.3
All soothing 70.9 5 Rich in soothing
All soothing
70.9
70
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Aloe Barbadensis Leaf Juice
Est. %70
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Simmondsia Chinensis (Jojoba) Seed Oil
Est. %4
Function
Origin
Simmondsia Chinensis (Jojoba) Seed OilA liquid plant wax, also known as Jojoba oil, pressed from the seeds of Simmondsia chinensis. These seeds can contain up to 50% of liquid wax. It is used as an occlusive moisturizer, emollient, and emulsifier.
Coconut Alkanes
Est. %3
Function
Origin
Coconut AlkanesAn occlusive moisturizing and emollient mixture that is similar to paraffin. It is produced from coconut oil and can allegedly form a soft, non-greasy film on the skin’s surface. It can be used as an alternative to silicones.
Glyceryl Stearate
Est. %2
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Stearic Acid
Est. %1.5
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Pyrus Malus (Apple) Juice
Est. %1.3
Function
Origin
Pyrus Malus (Apple) Juice
Vitis Vinifera (Grape) Juice
Est. %1
Function
Origin
Vitis Vinifera (Grape) JuiceA grape-derivative with numerous beneficial antioxidant, astringent, and exfoliating compounds.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) Seed OilA fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Glyceryl Stearate Citrate
Est. %0.3
Function
Origin
Glyceryl Stearate CitrateAn ingredient composed of citric acid, stearic acid, and glycerin. Glyceryl stearate citrate acts as an emollient in skincare products, making the skin appear smooth and pleasant to the touch.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Stearyl Alcohol
Est. %0.3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Oenothera Biennis Leaf Cell Extract
Est. %0.3
Function
Origin
Oenothera Biennis Leaf Cell Extract
Butyrospermum Parkii (Shea) Butter
Est. %0.3
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
Gossypium Herbaceum (Cotton) Seed Oil
Est. %0.3
Function
Origin
Gossypium Herbaceum (Cotton) Seed OilDerived from the seeds of the cotton plant, this emollient and occlusive fatty oil is mainly comprised of linoleic and palmitic acids. It also contains large amounts of phospholipids - key components of all cell membranes.
Linum Usitatissimum (Linseed) Seed Oil
Est. %0.3
Function
Origin
Linum Usitatissimum (Linseed) Seed OilAn emollient and occlusive fatty oil pressed from flax seeds. It is the richest source of linolenic fatty acid (it contains up to 50% of it) among vegetable oils.
Bidens Pilosa Extract
Est. %0.3
Function
Origin
Bidens Pilosa Extract
Astrocaryum Murumuru Seed Butter
Est. %0.3
Function
Origin
Astrocaryum Murumuru Seed ButterA butter-like, occlusive moisturizing, and emollient fatty oil extracted from the seeds of Murumuru palm. It consists mainly of lauric and myristic acid, as well as smaller amounts of oleic acid.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Ubiquinone
Est. %0.3
Function
Origin
UbiquinoneAlso known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Magnesium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Magnesium Ascorbyl PhosphateOne of the best-researched derivatives of vitamin C. It is more resistant to light and air and retains all the properties of ascorbic acid – antioxidant, collagen-boosting, and anti-pigmentation, but with less irritation.
Coco-Caprylate/Caprate
Est. %0.3
Function
Origin
Coco-Caprylate/CaprateA naturally-derived emollient ester. It is a blend of caprylates and caprates and, relative to other emollients, is lightweight and dry on the skin. As a result, coco-caprylate/caprate serves as a natural alternative to volatile silicones.
Malus Domestica Fruit Cell Culture Extract
Est. %0.3
Function
Origin
Malus Domestica Fruit Cell Culture ExtractAn extract that comes from a certain apple cultivar. It is claimed to have superior properties over any other apple extracts and the patent holder claims that it has anti-wrinkle activity.
Vitis Vinifera (Grape) Fruit Cell Extract
Est. %0.3
Function
Origin
Vitis Vinifera (Grape) Fruit Cell ExtractA cell culture extract obtained from a red grape with claimed antioxidant, astringent, and photoprotective properties.
Citrus Limon (Lemon) Leaf Extract
Est. %0.3
Function
Origin
Citrus Limon (Lemon) Leaf Extract
Camellia Sinensis Extract
Est. %0.3
Function
Origin
Camellia Sinensis Extract

An antioxidant, astringent, and soothing extract derived from green tea. It performs as an anti-aging ingredient in the deeper layers of the skin.

Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Mica
Est. %0.3
Function
Origin
MicaA mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
Titanium Dioxide (CI 77891)One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Diheptyl Succinate
Est. %0.3
Function
Origin
Diheptyl SuccinateA naturally-derived ingredient made from castor oil and wheat . Usually it is part of an ingredient blend as an alternative to silicones. It helps improve the spread of a product and reduce tackiness while remaining light on the skin.
Polyglyceryl-6 Distearate
Est. %0.3
Function
Origin
Polyglyceryl-6 Distearate
Capryloyl Glycerin/Sebacic Acid Copolymer
Est. %0.3
Function
Origin
Capryloyl Glycerin/Sebacic Acid CopolymerA naturally-derived film-former that increases water resistance of a product. It is also referred to as an alternative to dimethicone.
Thioctic Acid
Est. %0.3
Function
Origin
Thioctic Acid
Litsea Cubeba Fruit Oil
Est. %0.3
Function
Origin
Litsea Cubeba Fruit OilA lemon-scented essential oil distilled from the fruits of an evergreen tree native to Southeast Asia.
Cinnamomum Camphora (Camphor) Bark Oil
Est. %0.3
Function
Origin
Cinnamomum Camphora (Camphor) Bark Oil