Derm Institute Anti-Oxidant Hydration Serum

Derm Institute Anti-Oxidant Hydration Serum
3.8
/ 10
Moisturizing
7.2 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
$$$$

Review

Results you may expect from using Derm Institute Anti-Oxidant Hydration Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Derm Institute Anti-Oxidant Hydration Serum:

  • Light moisturizing. It has a moisturizing rating of 3.8 out of 10.
  • Little anti-wrinkle effect: Derm Institute Anti-Oxidant Hydration Serum has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Soothing: Derm Institute Anti-Oxidant Hydration Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Lightly moisturizing: Derm Institute Anti-Oxidant Hydration Serum has a moisturizing rating of 3.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a high humectancy of 7.2 out of 10, primarily due to Sodium Hyaluronate (est. ≈1.5%), Pentylene Glycol (est. ≈1.1%) and Propanediol (est. ≈1.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Derm Institute Anti-Oxidant Hydration Serum has a minimal anti-wrinkle rating of 0.4 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈0.3%),
 one of the most effective and well-researched anti-wrinkle ingredients.
 
Among others, Derm Institute Anti-Oxidant Hydration Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Camellia Sinensis Leaf Extract, Melia Azadirachta Leaf Extract, and Ubiquinone. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Derm Institute Anti-Oxidant Hydration Serum is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈1.5%), Malpighia Emarginata (Acerola) Fruit Extract (est. ≈1.4%), Algae Extract (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Derm Institute Anti-Oxidant Hydration Serum is rich (> 5%) in soothing ingredients, particularly Cucumis Sativus (Cucumber) Fruit Extract (est. ≈6.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
75
6
1.5
1.4
1.3
1.2
1.1
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
7.2
1.5
1.1
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
3.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.2 10
7.2
1.5
1.1
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
3.8
Ingredient Est. % Benchmark Humectancy
1.5
1.1
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 7.2 10
7.2
All humectants
7.2
1.5
1.1
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.4
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.2 3 Rich in antioxidants
All antioxidants
6.2
Sodium Hyaluronate
1.5
Malpighia Emarginata (Acerola) Fruit Extract
1.4
Niacinamide
0.3
Algae Extract
0.3
Ergothioneine
0.3
Camellia Sinensis Leaf Extract
0.3
Melia Azadirachta Leaf Extract
0.3
Angelica Acutiloba Root Extract
0.3
Mentha Piperita (Peppermint) Leaf Extract
0.3
Veronica Officinalis Extract
0.3
Melissa Officinalis Leaf Extract
0.3
Ubiquinone
0.3
Colloidal Platinum
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 9.6 5 Rich in soothing
All soothing
9.6
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Cucumis Sativus (Cucumber) Fruit Extract
Est. %6
Function
Origin
A soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Sodium Hyaluronate
Est. %1.5
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Malpighia Emarginata (Acerola) Fruit Extract
Est. %1.4
Function
Origin
An extract obtained from the fruits of acerola cherry. It is packed with potent antioxidant vitamin C and carotenoids.
Sodium Polyacrylate
Est. %1.3
Function
Origin
This white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Trideceth-6
Est. %1.2
Function
Origin
Description is coming soon
Pentylene Glycol
Est. %1.1
Function
Origin
A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.
Propanediol
Est. %1
Function
Origin
An excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Algae Extract
Est. %0.3
Function
Origin
The name describes any extract made from any kind of algae. Algae extracts are moisturizing humectants – the gelatin-like polysaccharides bind and retain water, thereby hydrating the skin. Algae is a rich source of emollient and antioxidant compounds.
Alpinia Galanga Leaf Extract
Est. %0.3
Function
Origin
Description is coming soon
Ethoxydiglycol
Est. %0.3
Function
Origin
A type of alcohol with humectant moisturizing properties. It also acts as a solvent, since it mixes well with a variety of other compounds, including water and even some oils.
Niacinamide
Est. %0.3
Function
Origin

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Polyquaternium-51
Est. %0.3
Function
Origin
A biocompatible phospholipid copolymer that is designed to mimic the lipid-based cell membrane found in human skin. Its main function is as a humectant moisturizer.
Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Oleic Acid
Est. %0.3
Function
Origin
An omega-9 fatty acid commonly found in vegetable oils. It is occlusive moisturizing, emollient and emulsifying.
Ergothioneine
Est. %0.3
Function
Origin
A naturally-occurring amino acid that functions as a powerful and versatile antioxidant.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Leuconostoc/Radish Root Ferment Filtrate
Est. %0.3
Function
Origin
A biotechnological fermentation ingredient that is created by feeding radish root to Leuconostoc kimchii. It allegedly contains organic acids and a mixture of peptides known as bacteriocins – which have antimicrobial activity.
Bacopa Monnieri Extract
Est. %0.3
Function
Origin
Description is coming soon
Poria Cocos Extract
Est. %0.3
Function
Origin
Description is coming soon
Squalane
Est. %0.3
Function
Origin
An occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Bisabolol
Est. %0.3
Function
Origin
An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
An antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Angelica Acutiloba Root Extract
Est. %0.3
Function
Origin
Angelica acutiloba root extract is a pungent, aromatic extract derived from the roots of the Japanese angelica tree. It has soothing effects and can be beneficial for itchy or allergy-prone skin [1]. It also contains antioxidants and protects the skin against UV-induced damage.
Sodium Acrylates Copolymer
Est. %0.3
Function
Origin
A synthetic polymer that can come in various forms and is often used to create light gel-like textures. Some versions can also create a light film on the skin.
Hydrogenated Polydecene
Est. %0.3
Function
Origin
A clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
PPG-1 Trideceth-6
Est. %0.3
Function
Origin
Description is coming soon
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Ethylhexylglycerin
Est. %0.3
Function
Origin
A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Acetyl Tyrosine
Est. %0.3
Function
Origin
Acetyl tyrosine is a derivative of the amino acid tyrosine. It is used as a tanning agent in skincare, helping pigment cells (melanosomes) to produce more dark skin pigment.
Proline
Est. %0.3
Function
Origin
The best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Hydrolyzed Vegetable Protein
Est. %0.3
Function
Origin
A blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Adenosine Triphosphate
Est. %0.3
Function
Origin
A cellular energy source that is thought to revitalize skin cells.
Allantoin
Est. %0.3
Function
Origin
A fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Panthenol
Est. %0.3
Function
Origin
A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Sodium Polyglutamate
Est. %0.3
Function
Origin
Description is coming soon
Carrageenan
Est. %0.3
Function
Origin
A gum-like thickener derived from a species of red algae called Irish moss. It helps to form a soft film on the skin, and aids in stabilizing product forms.
Malva Sylvestris (Mallow) Extract
Est. %0.3
Function
Origin
A vibrant, purple extract obtained from the dark flowers of common mallow. Its main active ingredient is an emollient and soothing thick mucilage.
Mentha Piperita (Peppermint) Leaf Extract
Est. %0.3
Function
Origin
A fragrant extract derived from the leaves of peppermint. It contains a pleasant-smelling essential oil, as well as plenty of antioxidant flavonoids, terpenes, and phenolic acids.
Primula Veris Extract
Est. %0.3
Function
Origin
Derived from either the root or flower of the cowslip primrose, this soothing extract contains anti-inflammatory triterpene saponins and phenolic acids.
Alchemilla Vulgaris Extract
Est. %0.3
Function
Origin
A soothing extract that is derived from the lady's mantle plant. It contains plenty of astringent tannins and certain anti-inflammatory compounds.
Veronica Officinalis Extract
Est. %0.3
Function
Origin
An antioxidant extract obtained from a native European flowering plant called heath speedwell, otherwise known as Paul's betony.
Melissa Officinalis Leaf Extract
Est. %0.3
Function
Origin
A fragrant extract derived from lemon balm leaves with antioxidant and antiviral flavonoids and terpenes. It has a lovely, fresh, lemon-like scent.
Achillea Millefolium Extract
Est. %0.3
Function
Origin
An extract obtained from the common yarrow. It is full of astringent and anti-inflammatory phytochemicals that help with inflamed skin and wound healing, have soothing and refreshing effects on the skin, and give the product a fresh, green, and spicy scent.
Ubiquinone
Est. %0.3
Function
Origin
Also known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Potassium Hydroxide
Est. %0.3
Function
Origin
A very alkaline ingredient, meaning that it has a high pH. Potassium hydroxide is therefore useful in bringing a low pH in a cosmetic product up to a more neutral, skin-safe level.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Tris(Tetramethylhydroxypiperidinol) Citrate
Est. %0.3
Function
Origin
Description is coming soon
Capryloyl Heptapeptide-12
Est. %0.3
Function
Origin
Description is coming soon
Gold (CI 77480)
Est. %0.3
Function
Origin

A colorant used in skincare, typically processed into fine particles for uniform dispersion. Its luxurious hue enhances product aesthetics, while its role as a slip and surface modifier improves texture and application. Despite touted anti-aging benefits, definitive scientific evidence is lacking.

Acetyl Tetrapeptide-17
Est. %0.3
Function
Origin
Description is coming soon
Colloidal Platinum
Est. %0.3
Function
Origin
Description is coming soon