Coxir Intensive EGF Peptide Cream

Coxir Intensive EGF Peptide Cream
5.8
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.6 Occlusivity icon Occlusivity
2.2Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Results you may expect from using Coxir Intensive EGF Peptide Cream:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Coxir Intensive EGF Peptide Cream:

  • Moderate moisturizing. It has a moisturizing rating of 5.8 out of 10.
  • Some anti-wrinkle efficacy: Coxir Intensive EGF Peptide Cream has an anti-wrinkle rating of 2.2 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Coxir Intensive EGF Peptide Cream has a moisturizing rating of 5.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.6 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%), Propylene Glycol (est. ≈4.0%) and Methyl Gluceth-20 (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Coxir Intensive EGF Peptide Cream has a slight anti-wrinkle rating of 2.2 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈1.5%), 
 one of the most effective and well-researched anti-wrinkle ingredients.
 
Among others, Coxir Intensive EGF Peptide Cream also contains some ingredients marketed as effective in reducing wrinkles, specifically Adenosine, sh-Oligopeptide-1, and Copper Tripeptide-1. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Coxir Intensive EGF Peptide Cream is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈1.5%), Copper Tripeptide-1 (est. ≈0.3%), Myrciaria Dubia Fruit Extract (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
60
Water
9
Glycerin
6
Glyceryl Acetate
4
Propylene Glycol
3
Butylene Glycol Dicaprylate/Dicaprate
2.5
Dimethicone/Vinyl Dimethicone Crosspolymer
2
Methyl Gluceth-20
1.5
Niacinamide
1.3
1,2-Hexanediol
1
Betaine
0.3
Diisostearyl Malate
0.3
Cyclomethicone
0.3
PEG/PPG-18/4 Copolymer
0.3
Sodium Caprylate
0.3
Isohexadecane
0.3
Polysorbate 80
0.3
Adenosine
0.3
Butylene Glycol
0.3
Hydrogenated Lecithin
0.3
sh-Oligopeptide-1
0.3
Copper Tripeptide-1
0.3
Hydrogenated Vegetable Oil
0.3
Tri-C14-15 Alkyl Citrate
0.3
Myrciaria Dubia Fruit Extract
0.3
Malpighia Emarginata Fruit Extract
0.3
Tocopheryl Acetate
0.3
Arginine
0.3
Carbomer
0.3
Panthenol
0.3
Lonicera Japonica (Honeysuckle) Flower Extract
0.3
Solanum Lycopersicum (Tomato) Fruit Extract
0.3
Lilium Tigrinum Extract
0.3
Nelumbo Nucifera Seed Extract
0.3
Chrysanthemum Indicum Flower Extract
0.3
Hydrolyzed Collagen
0.3
Acanthopanax Senticosus (Eleuthero) Root Extract
0.3
Punica Granatum Fruit Extract
0.3
Panax Ginseng Root Extract
0.3
Carthamus Tinctorius (Safflower) Flower Extract
0.3
Xanthan Gum
0.3
Malva Sylvestris (Mallow) Flower Extract
0.3
Buddleja Davidii Extract
0.3
Thymus Vulgaris (Thyme) Extract
0.3
Camellia Sinensis Callus Culture Extract
0.3
Phaseolus Radiatus Meristem Cell Culture Extract
0.3
Panax Ginseng Callus Culture Extract
0.3
Phenoxyethanol
0.3
Ethylhexylglycerin
0.3
Fragrance
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Glyceryl Acetate
Function:
Origin:
Propylene Glycol
Function:
Origin:
Butylene Glycol Dicaprylate/Dicaprate
Function:
Origin:
Dimethicone/Vinyl Dimethicone Crosspolymer
Function:
Origin:
Methyl Gluceth-20
Function:
Origin:
Niacinamide
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Betaine
Function:
Origin:
Diisostearyl Malate
Function:
Origin:
Cyclomethicone
Function:
Origin:
PEG/PPG-18/4 Copolymer
Function:
Origin:
Sodium Caprylate
Function:
Origin:
Isohexadecane
Function:
Origin:
Polysorbate 80
Function:
Origin:
Adenosine
Function:
Origin:
Butylene Glycol
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
sh-Oligopeptide-1
Function:
Origin:
Copper Tripeptide-1
Function:
Origin:
Hydrogenated Vegetable Oil
Function:
Origin:
Tri-C14-15 Alkyl Citrate
Function:
Origin:
Myrciaria Dubia Fruit Extract
Function:
Origin:
Malpighia Emarginata Fruit Extract
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Arginine
Function:
Origin:
Carbomer
Function:
Origin:
Panthenol
Function:
Origin:
Lonicera Japonica (Honeysuckle) Flower Extract
Function:
Origin:
Solanum Lycopersicum (Tomato) Fruit Extract
Function:
Origin:
Lilium Tigrinum Extract
Function:
Origin:
Nelumbo Nucifera Seed Extract
Function:
Origin:
Chrysanthemum Indicum Flower Extract
Function:
Origin:
Hydrolyzed Collagen
Function:
Origin:
Acanthopanax Senticosus (Eleuthero) Root Extract
Function:
Origin:
Punica Granatum Fruit Extract
Function:
Origin:
Panax Ginseng Root Extract
Function:
Origin:
Carthamus Tinctorius (Safflower) Flower Extract
Function:
Origin:
Xanthan Gum
Function:
Origin:
Malva Sylvestris (Mallow) Flower Extract
Function:
Origin:
Buddleja Davidii Extract
Function:
Origin:
Thymus Vulgaris (Thyme) Extract
Function:
Origin:
Camellia Sinensis Callus Culture Extract
Function:
Origin:
Phaseolus Radiatus Meristem Cell Culture Extract
Function:
Origin:
Panax Ginseng Callus Culture Extract
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
19.0
9
4
2
1.5
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
3.3
3.0
0.3
Benchmark
20
Moisturizing rating
5.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 19.0 10
10.0
9
4
2
1.5
1
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 3.3 20
1.6
3.0
0.3
Moisturizing rating
5.8
Ingredient Est. % Benchmark Humectancy
9
4
2
1.5
1
0.3
0.3
0.3
0.3
0.3
All humectants 19.0 10
10
All humectants
19.0
9
4
2
1.5
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
3
0.3
All occlusives 3.3 20
1.6
All occlusives
3.3
3.0
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1.5 2.2
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.2
Niacinamide
2.2
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1.5
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
sh-Oligopeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.2
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 4.8 3 Rich in antioxidants
All antioxidants
4.8
Niacinamide
1.5
Copper Tripeptide-1
0.3
Myrciaria Dubia Fruit Extract
0.3
Malpighia Emarginata Fruit Extract
0.3
Tocopheryl Acetate
0.3
Lonicera Japonica (Honeysuckle) Flower Extract
0.3
Solanum Lycopersicum (Tomato) Fruit Extract
0.3
Nelumbo Nucifera Seed Extract
0.3
Punica Granatum Fruit Extract
0.3
Panax Ginseng Root Extract
0.3
Buddleja Davidii Extract
0.3
Thymus Vulgaris (Thyme) Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.5
0.3
0.3
0.3
0.3
0.3
All soothing 3 5 No
All soothing
3
1.5
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Glyceryl Acetate
Est. %6
Function
Origin
Glyceryl Acetate
Propylene Glycol
Est. %4
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Butylene Glycol Dicaprylate/Dicaprate
Est. %3
Function
Origin
Butylene Glycol Dicaprylate/Dicaprate

Description is coming soon

Dimethicone/Vinyl Dimethicone Crosspolymer
Est. %2.5
Function
Origin
Dimethicone/Vinyl Dimethicone CrosspolymerThis ingredient can refer to several kinds of dimethicone crosspolymers. Like other silicones, it makes products feel slippery and non-greasy but can also increase the thickness or improve the water-resistance of a formula.
Methyl Gluceth-20
Est. %2
Function
Origin
Methyl Gluceth-20A humectant synthetically derived from glucose. It takes on the form of a clear, syrupy liquid.
Niacinamide
Est. %1.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

1,2-Hexanediol
Est. %1.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Betaine
Est. %1
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Diisostearyl Malate
Est. %0.3
Function
Origin
Diisostearyl MalateAn emollient ester that softens the skin and keeps it feeling smooth. It is characterized by a cushiony feel and glossy sheen, which is why it is frequently used in lip products.
Cyclomethicone
Est. %0.3
Function
Origin
CyclomethiconeA blend of emollient silicones that leaves a smooth and non-greasy after-feel. Unlike other types of oils, it does not leave any residue on the skin, which is part of what makes it so popular.
PEG/PPG-18/4 Copolymer
Est. %0.3
Function
Origin
PEG/PPG-18/4 Copolymer
Sodium Caprylate
Est. %0.3
Function
Origin
Sodium Caprylate
Isohexadecane
Est. %0.3
Function
Origin
IsohexadecaneA clear, colorless liquid that is commonly used as an emollient. It is made up of pure hydrocarbons and leaves a dry feeling on the skin upon application. It also increases the spreadability of a product.
Polysorbate 80
Est. %0.3
Function
Origin
Polysorbate 80A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Butylene Glycol
Est. %0.3
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
sh-Oligopeptide-1
Est. %0.3
Function
Origin
sh-Oligopeptide-1

Also known as Human Epidermal Growth Factor. It increases metabolism in skin cells and is claimed to improves skin texture and elasticity.

Copper Tripeptide-1
Est. %0.3
Function
Origin
Copper Tripeptide-1

A skin-identical, copper-binding peptide that promotes the synthesis of all structural elements in the skin.

Hydrogenated Vegetable Oil
Est. %0.3
Function
Origin
Hydrogenated Vegetable OilA solid, butter-like substance that is a highly occlusive moisturizer and emollient. It is a mixture of various plant oils (such as soy, olive, corn, canola, peanut, and many others) which has been refined.
Tri-C14-15 Alkyl Citrate
Est. %0.3
Function
Origin
Tri-C14-15 Alkyl Citrate
Myrciaria Dubia Fruit Extract
Est. %0.3
Function
Origin
Myrciaria Dubia Fruit ExtractAn extract obtained from the berry pulp of the camu camu bushy tree, which boasts a uniquely high concentration of vitamin C. The extract also contains emollient fatty acids and moisturizing amino acids.
Malpighia Emarginata Fruit Extract
Est. %0.3
Function
Origin
Malpighia Emarginata Fruit Extract

Description is coming soon

Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Lonicera Japonica (Honeysuckle) Flower Extract
Est. %0.3
Function
Origin
Lonicera Japonica (Honeysuckle) Flower ExtractAn extract from the white flowers of the Japanese honeysuckle. Apart from an essential oil responsible for its jasmine-like scent, the extract also contains antioxidant and anti-inflammatory iridoids, flavonoids, and phenolic acids.
Solanum Lycopersicum (Tomato) Fruit Extract
Est. %0.3
Function
Origin
Solanum Lycopersicum (Tomato) Fruit ExtractA bright red extract obtained from tomato fruit. Its main bioactive compound is lycopene, a powerful antioxidant. It also contains other antioxidants like various phenolic acids and flavonoids.
Lilium Tigrinum Extract
Est. %0.3
Function
Origin
Lilium Tigrinum Extract
Nelumbo Nucifera Seed Extract
Est. %0.3
Function
Origin
Nelumbo Nucifera Seed Extract
Chrysanthemum Indicum Flower Extract
Est. %0.3
Function
Origin
Chrysanthemum Indicum Flower Extract
Hydrolyzed Collagen
Est. %0.3
Function
Origin
Hydrolyzed Collagen

A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.

Acanthopanax Senticosus (Eleuthero) Root Extract
Est. %0.3
Function
Origin
Acanthopanax Senticosus (Eleuthero) Root Extract
Punica Granatum Fruit Extract
Est. %0.3
Function
Origin
Punica Granatum Fruit ExtractA pomegranate fruit extract that contains antioxidant polyphenols and a rare emollient punicic acid. It is aimed at dry, irritated skin.
Panax Ginseng Root Extract
Est. %0.3
Function
Origin
Panax Ginseng Root ExtractDerived from the roots of the Korean Ginseng, this extract contains a mixture of antioxidant and soothing ginsenosides which are proven to reduce inflammation and treat eczema. The root is a major part of Chinese traditional medicine.
Carthamus Tinctorius (Safflower) Flower Extract
Est. %0.3
Function
Origin
Carthamus Tinctorius (Safflower) Flower ExtractA bright orange extract obtained from the flowers of the safflower plant. It has been shown to reduce the signs of photoaging, have anti-pigment activity, and promote hair growth. The studies on humans, however, are so far lacking.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Malva Sylvestris (Mallow) Flower Extract
Est. %0.3
Function
Origin
Malva Sylvestris (Mallow) Flower Extract
Buddleja Davidii Extract
Est. %0.3
Function
Origin
Buddleja Davidii ExtractAn extract of summer lilac with antioxidant and anti-inflammatory compounds such as iridoids, various terpenes, flavonoids, and phenolic acids. More research is needed in order to evaluate its functions.
Thymus Vulgaris (Thyme) Extract
Est. %0.3
Function
Origin
Thymus Vulgaris (Thyme) ExtractDerived from thyme, this antioxidant, antiseptic and fragrant extract consists mainly of thyme essential oil (with its spicy herbal scent), flavonoids, terpenes, and organic acids.
Camellia Sinensis Callus Culture Extract
Est. %0.3
Function
Origin
Camellia Sinensis Callus Culture Extract
Phaseolus Radiatus Meristem Cell Culture Extract
Est. %0.3
Function
Origin
Phaseolus Radiatus Meristem Cell Culture Extract
Panax Ginseng Callus Culture Extract
Est. %0.3
Function
Origin
Panax Ginseng Callus Culture Extract
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.