Wellderma G Plus Silver Peptide Ampoule Review

Wellderma G Plus Silver Peptide Ampoule
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Wellderma G Plus Silver Peptide Ampoule Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Wellderma G Plus Silver Peptide Ampoule has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Wellderma G Plus Silver Peptide Ampoule is effective in minimizing wrinkles.
✅ Soothing: Wellderma G Plus Silver Peptide Ampoule contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Wellderma G Plus Silver Peptide Ampoule

 
These are the key benefits you can expect from using Wellderma G Plus Silver Peptide Ampoule:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Wellderma G Plus Silver Peptide Ampoule is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Niacinamide (est. ≈4.0%) and Propanediol (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Wellderma G Plus Silver Peptide Ampoule has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈4.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Wellderma G Plus Silver Peptide Ampoule also contains some ingredients marketed often as effective in reducing wrinkles, specifically Copper Tripeptide-1, Adenosine, and Melia Azadirachta Leaf Extract. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Wellderma G Plus Silver Peptide Ampoule is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Wellderma G Plus Silver Peptide Ampoule is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈4.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Wellderma G Plus Silver Peptide Ampoule

 
Here’s an overview of the pros and cons of Wellderma G Plus Silver Peptide Ampoule to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients, specifically Niacinamide
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Wellderma G Plus Silver Peptide Ampoule

 
Based on the ingredient list analysis, CreamScan AI suggests that Wellderma G Plus Silver Peptide Ampoule
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, Wellderma G Plus Silver Peptide Ampoule helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
Propanediol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Polyglycerin-3
Function:
Origin:
CI 77015
Function:
Origin:
Titanium Dioxide (CI 77891)
Function:
Origin:
Calcium Alginate
Function:
Origin:
Gellan Gum
Function:
Origin:
Agar
Function:
Origin:
Iron Oxides (CI 77492)
Function:
Origin:
Copper Tripeptide-1
Function:
Origin:
sh-Decapeptide-7
Function:
Origin:
sh-Octapeptide-4
Function:
Origin:
sh-Oligopeptide-9
Function:
Origin:
Nicotinoyl Tripeptide-1
Function:
Origin:
Lysine
Function:
Origin:
Histidine
Function:
Origin:
Arginine
Function:
Origin:
Aspartic Acid
Function:
Origin:
Threonine
Function:
Origin:
Serine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Proline
Function:
Origin:
Glycine
Function:
Origin:
Alanine
Function:
Origin:
Valine
Function:
Origin:
Methionine
Function:
Origin:
Isoleucine
Function:
Origin:
Leucine
Function:
Origin:
Tyrosine
Function:
Origin:
Phenylalanine
Function:
Origin:
Cysteine
Function:
Origin:
Punica Granatum Fruit Extract
Function:
Origin:
Ficus Carica (Fig) Fruit Extract
Function:
Origin:
Morus Alba Fruit Extract
Function:
Origin:
Ginkgo Biloba Nut Extract
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
PEG-60 Hydrogenated Castor Oil
Function:
Origin:
Adenosine
Function:
Origin:
Carbomer
Function:
Origin:
Hydroxyethylcellulose
Function:
Origin:
Silver Sulfate
Function:
Origin:
Melia Azadirachta Leaf Extract
Function:
Origin:
Eclipta Prostrata Extract
Function:
Origin:
Ocimum Sanctum Leaf Extract
Function:
Origin:
Corallina Officinalis Extract
Function:
Origin:
Moringa Oleifera Seed Oil
Function:
Origin:
Disodium EDTA
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
18.7
6
4
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 18.7 10
10.0
6
4
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
4
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 18.7 10
10
All humectants
18.7
6
4
3
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
Copper Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 7.6 3 Rich in antioxidants
All antioxidants
7.6
Niacinamide
4
Copper Tripeptide-1
0.3
sh-Decapeptide-7
0.3
sh-Octapeptide-4
0.3
Nicotinoyl Tripeptide-1
0.3
Cysteine
0.3
Punica Granatum Fruit Extract
0.3
Morus Alba Fruit Extract
0.3
Sodium Hyaluronate
0.3
Melia Azadirachta Leaf Extract
0.3
Ocimum Sanctum Leaf Extract
0.3
Corallina Officinalis Extract
0.3
Moringa Oleifera Seed Oil
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
0.3
0.3
0.3
0.3
0.3
All soothing 5.5 5 Rich in soothing
All soothing
5.5
4
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Niacinamide
Est. %4
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Propanediol
Est. %3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
1,2-Hexanediol
Est. %2
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Polyglycerin-3
Est. %1.5
Function
Origin
Polyglycerin-3
CI 77015
Est. %1.3
Function
Origin
CI 77015
Titanium Dioxide (CI 77891)
Est. %1
Function
Origin
Titanium Dioxide (CI 77891)One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Calcium Alginate
Est. %0.3
Function
Origin
Calcium Alginate
Gellan Gum
Est. %0.3
Function
Origin
Gellan GumA polysaccharide gel created by a species of bacteria called Sphingomonas elodea. It is used to either create soft, viscous, elastic gels or hard, brittle gels.
Agar
Est. %0.3
Function
Origin
AgarA multifunctional jelly derived from red algae that can thicken water-based products.
Iron Oxides (CI 77492)
Est. %0.3
Function
Origin
Iron Oxides (CI 77492)Also known as iron (III) oxide, this ingredient is a yellow-colored pigment that can either be derived from minerals or produced synthetically. It adds yellow tones to cosmetic products.
Copper Tripeptide-1
Est. %0.3
Function
Origin
Copper Tripeptide-1

A skin-identical, copper-binding peptide that promotes the synthesis of all structural elements in the skin.

sh-Decapeptide-7
Est. %0.3
Function
Origin
sh-Decapeptide-7
sh-Octapeptide-4
Est. %0.3
Function
Origin
sh-Octapeptide-4
sh-Oligopeptide-9
Est. %0.3
Function
Origin
sh-Oligopeptide-9
Nicotinoyl Tripeptide-1
Est. %0.3
Function
Origin
Nicotinoyl Tripeptide-1
Lysine
Est. %0.3
Function
Origin
LysineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It is slightly alkaline and helps to balance the product's pH. It may have a slightly fishy smell.
Histidine
Est. %0.3
Function
Origin
HistidineA humectant moisturizing amino acid with weak antioxidant effects that is a part of the skin’s Natural Moisturizing Factor. It can attract water to the skin’s surface and is slightly alkaline, thereby helping to balance a product's pH.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Aspartic Acid
Est. %0.3
Function
Origin
Aspartic AcidA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to retain water on the skin’s surface and is slightly acidic, thereby helping to balance the pH of a skincare product.
Threonine
Est. %0.3
Function
Origin
ThreonineAn essential amino acid that may play a role in collagen production. However, more research is needed in order to confirm or deny these claims.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Valine
Est. %0.3
Function
Origin
ValineAn essential amino acid (meaning our body cannot make it on its own and we get it from food instead). Like some other amino acids, Valine is a part of the skin's Natural Moisturizing Factor.
Methionine
Est. %0.3
Function
Origin
MethionineMethionine is a sulfur-containing amino acid that is a part of all the proteins in the body. It supports hair growth, but other than that there isn't much information about its functions in personal care products.
Isoleucine
Est. %0.3
Function
Origin
IsoleucineA humectant moisturizing, essential amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to increase water content on the skin’s surface and can increase the barrier repair effects of ceramides.
Leucine
Est. %0.3
Function
Origin
LeucineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to increase water content on the skin’s surface and is often used in conjunction with anti-pigmentation products.
Tyrosine
Est. %0.3
Function
Origin
Tyrosine
Phenylalanine
Est. %0.3
Function
Origin
PhenylalanineAn essential amino acid used in the treatment of vitiligo and other pigmentation issues. It is considered less effective than other anti-pigment ingredients and is often used in combination with them.
Cysteine
Est. %0.3
Function
Origin
CysteineA multifunctional amino acid that acts as a reducing agent and an antioxidant.
Punica Granatum Fruit Extract
Est. %0.3
Function
Origin
Punica Granatum Fruit ExtractA pomegranate fruit extract that contains antioxidant polyphenols and a rare emollient punicic acid. It is aimed at dry, irritated skin.
Ficus Carica (Fig) Fruit Extract
Est. %0.3
Function
Origin
Ficus Carica (Fig) Fruit ExtractA humectant and emollient extract derived from fig fruits. It contains a variety of good phytochemicals such as phenolic acids, flavonoids, and tannins.
Morus Alba Fruit Extract
Est. %0.3
Function
Origin
Morus Alba Fruit Extract
Ginkgo Biloba Nut Extract
Est. %0.3
Function
Origin
Ginkgo Biloba Nut Extract
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

PEG-60 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
PEG-60 Hydrogenated Castor OilA white paste-like substance derived from castor oil that belongs to a group of ingredients called PEGs (polyethylene glycols). It acts as a perfume solubilizer that helps fragrance agents dissolve in water and as a cleansing agent.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Hydroxyethylcellulose
Est. %0.3
Function
Origin
HydroxyethylcelluloseA naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Silver Sulfate
Est. %0.3
Function
Origin
Silver Sulfate
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
Melia Azadirachta Leaf ExtractAn antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Eclipta Prostrata Extract
Est. %0.3
Function
Origin
Eclipta Prostrata ExtractA soothing extract of false daisy that contains a variety of active anti-inflammatory phytochemicals such as flavonoids, terpenes, phytosterols, and special compounds called thiopenes.
Ocimum Sanctum Leaf Extract
Est. %0.3
Function
Origin
Ocimum Sanctum Leaf ExtractAn extract derived from the leaves of Holy Basil, also known as Tulsi, a traditional herb used in Ayurveda medicine. It contains antioxidant and anti-inflammatory rosmarinic acid, galic acid, flavonoids, and a sweet-scented essential oil.
Corallina Officinalis Extract
Est. %0.3
Function
Origin
Corallina Officinalis ExtractAn extract from red marine alga, Corallina officinalis is used in skincare for its antioxidant properties. It also contains an immense amount of calcium and special, sulfur-containing polysaccharides.
Moringa Oleifera Seed Oil
Est. %0.3
Function
Origin
Moringa Oleifera Seed OilAn oil obtained from the seeds of Moringa oleifera, a fast-growing bush native to Northern India and the sub-Himalayan regions. It contains mainly oleic acid, as well as many additional anti-inflammatory compounds and high levels of vitamin E.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.