Skintific Gentle A Retinol Renewal Serum

Skintific Gentle A Retinol Renewal Serum
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
7.9Anti-wrinkle icon/ 10
Anti-wrinkle

Review

Does Skintific Gentle A Retinol Renewal Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Skintific Gentle A Retinol Renewal Serum:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 7.9 out of 10, Skintific Gentle A Retinol Renewal Serum is effective in minimizing wrinkles.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, Skintific Gentle A Retinol Renewal Serum is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%) and Glycerin (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Significant anti-wrinkle efficacy

According to CreamScan analysis, Skintific Gentle A Retinol Renewal Serum has a high anti-wrinkle rating of 7.9 out of 10.

It contains 3 active ingredients with proven anti-wrinkle efficacy:

  • Retinal (est. ≈0.05%),
     also known as retinaldehyde, is a potent retinoid with anti-wrinkle efficacy confirmed by a single clinical study involving 125 participants (Creidi et al.). This study demonstrated that a cream containing 0.05% retinal reduced the average wrinkle depth by 8% after 18 weeks of use, compared to a vehicle (the same formulation without retinal).
  • Retinol (est. ≈0.1%),
     the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
  • Niacinamide (est. ≈0.3%),
     one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
Among others, Skintific Gentle A Retinol Renewal Serum also contains some ingredients often marketed as effective in reducing wrinkles, specifically Hydroxypinacolone Retinoate, Palmitoyl Pentapeptide-4, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Centella Asiatica Extract, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
0.1
0.05
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Diethoxyethyl Succinate
Function:
Origin:
Retinol
Function:
Origin:
Retinal
Function:
Origin:
Dimethicone/Vinyl Dimethicone Crosspolymer
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Hydroxypinacolone Retinoate
Function:
Origin:
Niacinamide
Function:
Origin:
Propanediol
Function:
Origin:
Carbomer
Function:
Origin:
Ammonium Acryloyldimethyltaurate/VP Copolymer
Function:
Origin:
Calcium Alginate
Function:
Origin:
Agar
Function:
Origin:
Palmitoyl Pentapeptide-4
Function:
Origin:
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Function:
Origin:
Acetyl Tetrapeptide-5
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Disodium EDTA
Function:
Origin:
Ceramide AS
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Ceramide NS
Function:
Origin:
Tocopherol
Function:
Origin:
Ceramide NP
Function:
Origin:
Ceramide AP
Function:
Origin:
Ceramide EOP
Function:
Origin:
o-Cymen-5-ol
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Caprylhydroxamic Acid
Function:
Origin:
Gentiana Scabra Root Extract
Function:
Origin:
Piper Methysticum Leaf/Root/Stem Extract
Function:
Origin:
Carnosine
Function:
Origin:
Polygonum Bistorta Root Extract
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:

Ratings

All humectants
11.8
6
4
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 11.8 10
10.0
6
4
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
4
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 11.8 10
10
All humectants
11.8
6
4
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
5 /10 0.05 0.05 5
10 /10 0.4 0.1 2.5
6 /10 4 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
7.9
Retinal
5
Ingredient anti-wrinkle power
5 /10
when present at, %
0.05
in this formula, est. %
0.05
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Hydroxypinacolone Retinoate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Pentapeptide-4
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dipeptide Diaminobutyroyl Benzylamide Diacetate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
7.9
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 2.1 3 No
All antioxidants
2.1
Niacinamide
0.3
Hydroxypinacolone Retinoate
0.3
Sodium Hyaluronate
0.3
Centella Asiatica Extract
0.3
Tocopherol
0.3
o-Cymen-5-ol
0.3
Carnosine
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Diethoxyethyl Succinate
Est. %3
Function
Origin
Diethoxyethyl Succinate
Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Retinal
Est. %0.05
Function
Origin
Retinal

A potent ingredient of the retinoid group with confirmed anti-wrinkle capabilities.

Dimethicone/Vinyl Dimethicone Crosspolymer
Est. %0.3
Function
Origin
Dimethicone/Vinyl Dimethicone CrosspolymerThis ingredient can refer to several kinds of dimethicone crosspolymers. Like other silicones, it makes products feel slippery and non-greasy but can also increase the thickness or improve the water-resistance of a formula.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Hydroxypinacolone Retinoate
Est. %0.3
Function
Origin
Hydroxypinacolone RetinoateThe newest derivative of vitamin A with improved stability, less irritation, and (allegedly) direct vitamin A action. Studies recommend it for acne treatment and collagen-boosting effects.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Propanediol
Est. %0.3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %0.3
Function
Origin
Ammonium Acryloyldimethyltaurate/VP CopolymerA polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.
Calcium Alginate
Est. %0.3
Function
Origin
Calcium Alginate
Agar
Est. %0.3
Function
Origin
AgarA multifunctional jelly derived from red algae that can thicken water-based products.
Palmitoyl Pentapeptide-4
Est. %0.3
Function
Origin
Palmitoyl Pentapeptide-4

A famous synthetically made peptide that works as a signal peptide, telling skin cells to create more collagen and other structural proteins. It has been clinically tested and found to be effective at reducing fine wrinkles.

Dipeptide Diaminobutyroyl Benzylamide Diacetate
Est. %0.3
Function
Origin
Dipeptide Diaminobutyroyl Benzylamide DiacetateA synthetically made peptide similar to the proteins in viper venom. Similarly to Botox, it works by inhibiting contractions of mimic muscles, thereby offering a short-term reduction in mimic wrinkles.
Acetyl Tetrapeptide-5
Est. %0.3
Function
Origin
Acetyl Tetrapeptide-5

A synthetically made peptide that was designed to reduce puffy eyebags by regulating the water balance between blood vessels and the skin. It has not been independently tested yet.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Ceramide AS
Est. %0.3
Function
Origin
Ceramide AS
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Ceramide NS
Est. %0.3
Function
Origin
Ceramide NSA wax-like lipid natural to the skin’s lipid matrix. It is less frequently used but, in combination with other ceramides, can help to restore balance in the skin’s lipid barrier.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Ceramide AP
Est. %0.3
Function
Origin
Ceramide APPreviously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Ceramide EOP
Est. %0.3
Function
Origin
Ceramide EOP

Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.

o-Cymen-5-ol
Est. %0.3
Function
Origin
o-Cymen-5-olA preservative related to chemicals found in the herb thyme. It has its own unique smell but is very effective even at small amounts.
Pentylene Glycol
Est. %0.3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Caprylhydroxamic Acid
Est. %0.3
Function
Origin
Caprylhydroxamic AcidA chelating agent used alongside preservatives in order to boost their antimicrobial activity.
Gentiana Scabra Root Extract
Est. %0.3
Function
Origin
Gentiana Scabra Root Extract
Piper Methysticum Leaf/Root/Stem Extract
Est. %0.3
Function
Origin
Piper Methysticum Leaf/Root/Stem Extract
Carnosine
Est. %0.3
Function
Origin
CarnosineA skin-identical dipeptide that acts as a powerful antioxidant. It protects our skin from harmful glycation and can enhance the activity of other active ingredients in the skincare product.
Polygonum Bistorta Root Extract
Est. %0.3
Function
Origin
Polygonum Bistorta Root Extract
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.