A skin-identical dipeptide that acts as a powerful antioxidant. It protects our skin from harmful glycation and can enhance the activity of other active ingredients in the skincare product.


Carnosine is a naturally occurring peptide that plays many important roles in the human organism.

It is a dipeptide consisting of alanine and histidine and acts as an antioxidant in skin tissue, inactivating the products of oxidative stress and lipid peroxidation.

It has one interesting additional property – according to the latest research, it is able to prevent protein glycation. You have probably never heard of it, so let’s break it down into simple terms.

Sugar is fuel for our cells, but too much for too long can be damaging. Molecules of glucose might bind to proteins, creating so-called Advanced glycation end products (AGEs). AGEs are a common result of uncontrolled diabetes, although they tend to appear with age as well.

Collagen is particularly vulnerable to glycation because it is a long-living protein exposed to a lot of stress during its lifetime. Glycated collagen gradually loses its functionality and adds to skin aging. Studies suggest that carnosine is able to prevent this from happening – both as a nutritional supplement and in the form of 0,2% carnosine cream.

Carnosine is often added to anti-aging skincare products, where it improves the function of other active ingredients such as hyaluronic acid and other peptides.


Babizhayev M. A. (2006). Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products. Life sciences, 78(20), 2343–2357.
Babizhayev, M. A., et al. (2012). Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and skin aging. The Journal of dermatological treatment, 23(5), 345–384.
Narda, M., et al. (2018). Novel Facial Cream Containing Carnosine Inhibits Formation of Advanced Glycation End-Products in Human Skin. Skin pharmacology and physiology, 31(6), 324–331.
Guaitolini, E., et al. (2019). Randomized, Placebo-controlled Study of a Nutraceutical Based on Hyaluronic Acid, L-carnosine, and Methylsulfonylmethane in Facial Skin Aesthetics and Well-being. The Journal of clinical and aesthetic dermatology, 12(4), 40–45.
Garre, A., et al. (2017). Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study. Clinical, cosmetic and investigational dermatology, 10, 473–482.