SkinMedica Replenish Hydrating Cream

SkinMedica Replenish Hydrating Cream
5.3
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity

Review

Does SkinMedica Replenish Hydrating Cream work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using SkinMedica Replenish Hydrating Cream:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.3 out of 10.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, SkinMedica Replenish Hydrating Cream is quite moisturizing, with a moisturizing rating of 5.3 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Questionable anti-wrinkle efficacy

According to CreamScan analysis, SkinMedica Replenish Hydrating Cream has a zero anti-wrinkle rating.

It contains Magnesium Ascorbyl Phosphate, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Magnesium Ascorbyl Phosphate provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
60
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Sucrose Cocoate
Function:
Origin:
Isododecane
Function:
Origin:
Isohexadecane
Function:
Origin:
Cyclohexasiloxane
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Microcrystalline Cellulose
Function:
Origin:
Sodium PCA
Function:
Origin:
Phytosteryl Isostearate
Function:
Origin:
Allantoin Glycyrrhetinic Acid
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Ceramide NP
Function:
Origin:
Polysilicone-11
Function:
Origin:
Hydrolyzed Caesalpinia Spinosa Gum
Function:
Origin:
Caesalpinia Spinosa Gum
Function:
Origin:
Linoleic Acid
Function:
Origin:
Linolenic Acid
Function:
Origin:
Tocopherol
Function:
Origin:
Panicum Miliaceum (Millet) Seed Extract
Function:
Origin:
Bisabolol
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Camellia Oleifera Leaf Extract
Function:
Origin:
Magnesium Ascorbyl Phosphate
Function:
Origin:
Superoxide Dismutase
Function:
Origin:
Cetyl Hydroxyethylcellulose
Function:
Origin:
Cellulose Gum
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
Disodium EDTA
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
10.2
9
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.2 10
10.0
9
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
5.3
Ingredient Est. % Benchmark Humectancy
9
0.3
0.3
0.3
0.3
All humectants 10.2 10
10
All humectants
10.2
9
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
Total
0
Magnesium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 2.1 3 No
All antioxidants
2.1
Tocopheryl Acetate
0.3
Tocopherol
0.3
Sodium Hyaluronate
0.3
Camellia Oleifera Leaf Extract
0.3
Magnesium Ascorbyl Phosphate
0.3
Superoxide Dismutase
0.3
Hydroxyacetophenone
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Cyclopentasiloxane
Est. %6
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Cetyl Alcohol
Est. %4
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Stearyl Alcohol
Est. %3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Sucrose Cocoate
Est. %2.5
Function
Origin
Sucrose Cocoate
Isododecane
Est. %2
Function
Origin
IsododecaneAn emollient derived from petroleum with high spreadability. It is often used as a replacement for oils and silicones because it leaves no residue behind on the skin. When a product is labeled as “oil-free” it may contain isododecane instead of heavier oils.
Isohexadecane
Est. %1.5
Function
Origin
IsohexadecaneA clear, colorless liquid that is commonly used as an emollient. It is made up of pure hydrocarbons and leaves a dry feeling on the skin upon application. It also increases the spreadability of a product.
Cyclohexasiloxane
Est. %1.3
Function
Origin
CyclohexasiloxaneA clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Glyceryl Stearate
Est. %1
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Microcrystalline Cellulose
Est. %0.3
Function
Origin
Microcrystalline CelluloseA plant-based ingredient derived from cellulose. The rough version of microcrystalline cellulose is used in scrubs instead of plastic microbeads and the finer version is used as a thickener and stabilizer and readily absorbs oil and sweat.
Sodium PCA
Est. %0.3
Function
Origin
Sodium PCAOne of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Phytosteryl Isostearate
Est. %0.3
Function
Origin
Phytosteryl Isostearate
Allantoin Glycyrrhetinic Acid
Est. %0.3
Function
Origin
Allantoin Glycyrrhetinic Acid
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Polysilicone-11
Est. %0.3
Function
Origin
Polysilicone-11A synthetic rubber-like substance of the silicone family that has no color or distinct scent. These are large molecules that cannot penetrate the skin but instead create a thin silky film on the skin's surface.
Hydrolyzed Caesalpinia Spinosa Gum
Est. %0.3
Function
Origin
Hydrolyzed Caesalpinia Spinosa Gum
Caesalpinia Spinosa Gum
Est. %0.3
Function
Origin
Caesalpinia Spinosa GumA plant-based formula helper also known as Tara gum that contains thickening galactomannans (polysaccharides).
Linoleic Acid
Est. %0.3
Function
Origin
Linoleic AcidA fatty acid isolated from various plant oils (notably evening primrose, safflower, grape seed, and sunflower oil). It is an occlusive moisturizer and emollient that doesn't leave an oily, sticky residue and is especially suitable for oily and acne-prone skin.
Linolenic Acid
Est. %0.3
Function
Origin
Linolenic AcidAn essential polyunsaturated occlusive fatty acid isolated from various plant oils. It is necessary for the correct barrier function of the skin and moisturizes without leaving a sticky after-feel.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Panicum Miliaceum (Millet) Seed Extract
Est. %0.3
Function
Origin
Panicum Miliaceum (Millet) Seed Extract
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Camellia Oleifera Leaf Extract
Est. %0.3
Function
Origin
Camellia Oleifera Leaf ExtractAn emollient extract derived from the leaves of the Tea-oil Camellia, which is native to Southeast Asia. It contains astringent and wound-healing tannins that create a tightening feeling on the skin and can speed up the healing process of small cuts.
Magnesium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Magnesium Ascorbyl PhosphateOne of the best-researched derivatives of vitamin C. It is more resistant to light and air and retains all the properties of ascorbic acid – antioxidant, collagen-boosting, and anti-pigmentation, but with less irritation.
Superoxide Dismutase
Est. %0.3
Function
Origin
Superoxide Dismutase
Cetyl Hydroxyethylcellulose
Est. %0.3
Function
Origin
Cetyl HydroxyethylcelluloseA naturally-derived polymer that helps products feel buttery and bouncy and can reduce stringiness in a formula.
Cellulose Gum
Est. %0.3
Function
Origin
Cellulose GumA polymer that is derived from its namesake, cellulose, which is plant-based. It has many formula-helper benefits, including thickening and product stabilization.
Hydroxyacetophenone
Est. %0.3
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.