Shiseido WrinkleResist24 Protective Hand Revitalizer Review

Shiseido WrinkleResist24 Protective Hand Revitalizer
5.8
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.6 Occlusivity icon Occlusivity
Rich
in Antioxidants
Ingredients

Shiseido WrinkleResist24 Protective Hand Revitalizer Ingredients

Hover to see details. On mobile? Tap for ingredient stories!

Full Ingredient List (INCI):

Water, Glycerin, Octocrylene, Octinoxate, Dipropylene Glycol, Avobenzone, Caprylic/Capric Triglyceride, Oxybenzone, Behenyl Alcohol, Butylene Glycol, Isohexadecane, SD Alcohol 40-B, Sorbitol, Silica, Myristyl Myristate, Dimethicone, Polybutylene Glycol/PPG-9/1 Copolymer, Stearyl Alcohol, Triisostearin, Phytosteryl Macadamiate, Tocopheryl Acetate, 2-O-Ethyl Ascorbic Acid, Potassium Ascorbyl Tocopheryl Phosphate, Arginine HCl, Saxifraga Sarmentosa Extract, Sapindus Mukorossi Peel Extract, Panax Ginseng Root Extract, Angelica Acutiloba Root Extract, Sodium Acetylated Hyaluronate, Hydroxyproline, Uncaria Gambir Extract, Chlorella Vulgaris Extract, Thymus Serpyllum Extract, Beheneth-20, Alcohol, Succinoglycan, Trisodium EDTA, Sodium Citrate, Sodium Metaphosphate, Citric Acid, BHT, Sodium Metabisulfite, Tocopherol, Phenoxyethanol, Fragrance, Iron Oxides
Review

Does Shiseido WrinkleResist24 Protective Hand Revitalizer Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Shiseido WrinkleResist24 Protective Hand Revitalizer has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.8 out of 10.
✅ Antioxidant protection

  

Key Benefits of Shiseido WrinkleResist24 Protective Hand Revitalizer

 
These are the key benefits you can expect from using Shiseido WrinkleResist24 Protective Hand Revitalizer:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Shiseido WrinkleResist24 Protective Hand Revitalizer is quite moisturizing, with a moisturizing rating of 5.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.6 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Shiseido WrinkleResist24 Protective Hand Revitalizer is rich (> 3%) in antioxidants, specifically Tocopheryl Acetate (est. ≈0.3%), 2-O-Ethyl Ascorbic Acid (est. ≈0.3%), Potassium Ascorbyl Tocopheryl Phosphate (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Shiseido WrinkleResist24 Protective Hand Revitalizer

 
CreamScan identified a few things to consider before adding Shiseido WrinkleResist24 Protective Hand Revitalizer to your skincare routine:
 

⚠️ Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Shiseido WrinkleResist24 Protective Hand Revitalizer is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains 2-O-Ethyl Ascorbic Acid, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of 2-O-Ethyl Ascorbic Acid provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically rule out the possibility that 2-O-Ethyl Ascorbic Acid may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.

Therefore, this ingredient does not generate the anti-wrinkle rating.

📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Shiseido WrinkleResist24 Protective Hand Revitalizer

 
Here’s an overview of the pros and cons of Shiseido WrinkleResist24 Protective Hand Revitalizer to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ Questionable anti-wrinkle efficacy
   

Summary: Shiseido WrinkleResist24 Protective Hand Revitalizer

 
Based on the ingredient list analysis, CreamScan AI suggests that Shiseido WrinkleResist24 Protective Hand Revitalizer
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
With its high antioxidant content, Shiseido WrinkleResist24 Protective Hand Revitalizer helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Shiseido WrinkleResist24 Protective Hand Revitalizer worth noting.
 
If one of your main reasons for considering Shiseido WrinkleResist24 Protective Hand Revitalizer is its potential anti-aging effects, please note that, according to CreamScan analysis, its anti-wrinkle efficacy is questionable. None of the ingredients in this product provide substantial evidence of their anti-wrinkle efficacy according to CreamScan Research Evaluation Standards.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
60
9
5
4.9
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Octocrylene
Function:
Origin:
Octinoxate
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Avobenzone
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Oxybenzone
Function:
Origin:
Behenyl Alcohol
Function:
Origin:
Butylene Glycol
Function:
Origin:
Isohexadecane
Function:
Origin:
SD Alcohol 40-B
Function:
Origin:
Sorbitol
Function:
Origin:
Silica
Function:
Origin:
Myristyl Myristate
Function:
Origin:
Dimethicone
Function:
Origin:
Polybutylene Glycol/PPG-9/1 Copolymer
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Triisostearin
Function:
Origin:
Phytosteryl Macadamiate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
2-O-Ethyl Ascorbic Acid
Function:
Origin:
Potassium Ascorbyl Tocopheryl Phosphate
Function:
Origin:
Arginine HCl
Function:
Origin:
Saxifraga Sarmentosa Extract
Function:
Origin:
Sapindus Mukorossi Peel Extract
Function:
Origin:
Panax Ginseng Root Extract
Function:
Origin:
Angelica Acutiloba Root Extract
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:
Hydroxyproline
Function:
Origin:
Uncaria Gambir Extract
Function:
Origin:
Chlorella Vulgaris Extract
Function:
Origin:
Thymus Serpyllum Extract
Function:
Origin:
Beheneth-20
Function:
Origin:
Alcohol
Function:
Origin:
Succinoglycan
Function:
Origin:
Trisodium EDTA
Function:
Origin:
Sodium Citrate
Function:
Origin:
Sodium Metaphosphate
Function:
Origin:
Citric Acid
Function:
Origin:
BHT
Function:
Origin:
Sodium Metabisulfite
Function:
Origin:
Tocopherol
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Fragrance
Function:
Origin:
Iron Oxides
Function:
Origin:

Ratings

All humectants
10.9
9
1
0.3
0.3
0.3
Benchmark
10
All occlusives
3.2
2.0
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.9 10
10.0
9
1
0.3
0.3
0.3
Occlusivity All occlusives 3.2 20
1.6
2.0
0.3
0.3
0.3
0.3
Moisturizing rating
5.8
Ingredient Est. % Benchmark Humectancy
9
1
0.3
0.3
0.3
All humectants 10.9 10
10
All humectants
10.9
9
1
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2
0.3
0.3
0.3
0.3
All occlusives 3.2 20
1.6
All occlusives
3.2
2.0
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
Total
0
2-O-Ethyl Ascorbic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3 3 Rich in antioxidants
All antioxidants
3
Tocopheryl Acetate
0.3
2-O-Ethyl Ascorbic Acid
0.3
Potassium Ascorbyl Tocopheryl Phosphate
0.3
Saxifraga Sarmentosa Extract
0.3
Panax Ginseng Root Extract
0.3
Angelica Acutiloba Root Extract
0.3
Chlorella Vulgaris Extract
0.3
BHT
0.3
Sodium Metabisulfite
0.3
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Octocrylene
Est. %5
Function
Origin
OctocryleneA synthetic compound that protects skin against harmful ultraviolet light.
Octinoxate
Est. %4.9
Function
Origin
OctinoxateA chemical sunscreen also known as ethylhexyl methoxycinnamate. It protects against UVB, which causes the skin to burn and tan and can lead to certain types of skin cancers. For broad-spectrum protection claims, octinoxate should be paired with a UVA sunscreen.
Dipropylene Glycol
Est. %3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Avobenzone
Est. %2.5
Function
Origin
AvobenzoneA popular sunscreen that protects against UVA rays, which cause premature aging and skin cancer. Avobenzone degrades after about 30 minutes of sun exposure and becomes ineffective. It is therefore often paired with UV-filter stabilizers such as octocrylene.
Caprylic/Capric Triglyceride
Est. %2
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Oxybenzone
Est. %1.5
Function
Origin
OxybenzoneA chemical sunscreen that protects against burning caused by UVB radiation.
Behenyl Alcohol
Est. %1.3
Function
Origin
Behenyl AlcoholA fatty alcohol with emollient properties. It is used as a co-emulsifier and thickener and tends to result in a product with a smooth and creamy application texture.
Butylene Glycol
Est. %1
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Isohexadecane
Est. %0.3
Function
Origin
IsohexadecaneA clear, colorless liquid that is commonly used as an emollient. It is made up of pure hydrocarbons and leaves a dry feeling on the skin upon application. It also increases the spreadability of a product.
SD Alcohol 40-B
Est. %0.3
Function
Origin
SD Alcohol 40-BA natural ingredient containing a denaturant to discourage drinking.
Sorbitol
Est. %0.3
Function
Origin
SorbitolA sweet-tasting alcohol derived from glucose. Aside from its sweet taste (for which it is used as a very common sweetener), Sorbitol is also very good at retaining water and is used in skincare as a humectant.
Silica
Est. %0.3
Function
Origin
SilicaA widely used cosmetic ingredient with the same chemical composition as the sand found on beaches. A common function of silica is its ability to control viscosity. In certain chemical forms, it can effectively thicken cream-style products.
Myristyl Myristate
Est. %0.3
Function
Origin
Myristyl MyristateAn occlusive moisturizing and emollient ester that is derived from vegetables. This soft, wax-like ester produces a soft and creamy sensorial profile. Myristyl myristate is listed as a common comedogenic ingredient by acne.org.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Polybutylene Glycol/PPG-9/1 Copolymer
Est. %0.3
Function
Origin
Polybutylene Glycol/PPG-9/1 Copolymer
Stearyl Alcohol
Est. %0.3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Triisostearin
Est. %0.3
Function
Origin
Triisostearin
Phytosteryl Macadamiate
Est. %0.3
Function
Origin
Phytosteryl MacadamiateA richly emollient and occlusive moisturizing product of binding fatty acids from macadamia oil (mostly oleic and palmitoleic acid) with soybean oil phytosterols. It is also used as a formula helper.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

2-O-Ethyl Ascorbic Acid
Est. %0.3
Function
Origin
2-O-Ethyl Ascorbic AcidA derivative of vitamin C. There are no clinical studies on this ingredient as of yet, and so we don't know if it is as effective as the other ascorbic acid derivatives.
Potassium Ascorbyl Tocopheryl Phosphate
Est. %0.3
Function
Origin
Potassium Ascorbyl Tocopheryl Phosphate
Arginine HCl
Est. %0.3
Function
Origin
Arginine HClArginine HCl, or Arginine Hydrochloride, is an ionized, salt-like version of Arginine, one of the components of natural moisturizing factor (you can read more about this amino acid here). Their uses are basically the same, and both are used as humectant moisturizing ingredients in skincare products.
Saxifraga Sarmentosa Extract
Est. %0.3
Function
Origin
Saxifraga Sarmentosa ExtractA soothing extract obtained from the strawberry saxifrage plant. It contains antioxidant flavonoids.
Sapindus Mukorossi Peel Extract
Est. %0.3
Function
Origin
Sapindus Mukorossi Peel Extract
Panax Ginseng Root Extract
Est. %0.3
Function
Origin
Panax Ginseng Root ExtractDerived from the roots of the Korean Ginseng, this extract contains a mixture of antioxidant and soothing ginsenosides which are proven to reduce inflammation and treat eczema. The root is a major part of Chinese traditional medicine.
Angelica Acutiloba Root Extract
Est. %0.3
Function
Origin
Angelica Acutiloba Root ExtractAngelica acutiloba root extract is a pungent, aromatic extract derived from the roots of the Japanese angelica tree. It has soothing effects and can be beneficial for itchy or allergy-prone skin [1]. It also contains antioxidants and protects the skin against UV-induced damage.
Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.
Hydroxyproline
Est. %0.3
Function
Origin
HydroxyprolineAn amino acid that may promote collagen synthesis.
Uncaria Gambir Extract
Est. %0.3
Function
Origin
Uncaria Gambir Extract
Chlorella Vulgaris Extract
Est. %0.3
Function
Origin
Chlorella Vulgaris ExtractA dried mass of tiny, single-cell green algae. It is widely used as a food source or dietary supplement since it is rich in proteins, amino acids, minerals, and vitamins. This dark green extract is used as an antioxidant agent in skincare.
Thymus Serpyllum Extract
Est. %0.3
Function
Origin
Thymus Serpyllum Extract
Beheneth-20
Est. %0.3
Function
Origin
Beheneth-20
Alcohol
Est. %0.3
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
Succinoglycan
Est. %0.3
Function
Origin
Succinoglycan
Trisodium EDTA
Est. %0.3
Function
Origin
Trisodium EDTAA chelating agent designed to encapsulate potentially harmful heavy metal ions that enter the formula through the water source. Once encapsulated, these heavy metal ions become inert.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Sodium Metaphosphate
Est. %0.3
Function
Origin
Sodium MetaphosphateA sodium salt that captures heavy metal ions and raises the pH.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
BHT
Est. %0.3
Function
Origin
BHTAn antioxidant ingredient that naturally occurs in green algae and some bacteria or fungi but, for commercial use, is created synthetically. BHT is also used occasionally as a fragrance, where it presents a sweet, camphor-like odor.
Sodium Metabisulfite
Est. %0.3
Function
Origin
Sodium MetabisulfiteA preservative that is especially effective at preventing fungus and mold growth. It is normally combined with a strong bactericidal preservative in order to achieve broad-spectrum protection. Sodium metabisulfite is also used as an antioxidant.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Iron Oxides
Est. %0.3
Function
Origin
Iron OxidesMineral pigments used to provide color in skincare products. These naturally occurring pigments are available in yellow, red, brown, and black powders.