Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum

Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum
5.2
/ 10
Moisturizing
9.9 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
Rich
in Antioxidants
$$$$

Review

Results you may expect from using Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.2 out of 10.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum has a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a very high humectancy of 9.9 out of 10, primarily due to the high content of Propanediol (est. ≈6.0%) and Glycerin (est. ≈3.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum has a zero anti-wrinkle rating.

It contains Tetrahexyldecyl Ascorbate and Palmitoyl Tripeptide-38, two ingredients marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Perricone MD Essential Fx Acyl-Glutathione Eyelid Lift Serum is rich (> 3%) in antioxidants, specifically Tetrahexyldecyl Ascorbate (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
9.9
6
3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.9 10
9.9
6
3
0.3
0.3
0.3
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
6
3
0.3
0.3
0.3
All humectants 9.9 10
9.9
All humectants
9.9
6
3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 2 -
n/a
- 0.3 -
Total
0
Tetrahexyldecyl Ascorbate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
2
Palmitoyl Tripeptide-38
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
2
1.5
0.3
0.3
0.3
0.3
All antioxidants 4.7 3 Rich in antioxidants
All antioxidants
4.7
Tetrahexyldecyl Ascorbate
2
S-Palmitoylglutathione
1.5
Avena Sativa (Oat) Kernel Extract
0.3
Salvia Hispanica Seed Oil
0.3
Sodium Hyaluronate
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
All soothing 0.6 5 No
All soothing
0.6
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Propanediol
Est. %6
Function
Origin
An excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Pantethine
Est. %4
Function
Origin
A synthetic emollient that provides a soft and smooth feeling to skin. Most emollients are oil-based, but pantethine dissolves in water.
Glycerin
Est. %3
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Tetrahexyldecyl Ascorbate
Est. %2
Function
Origin
A lipid-soluble form of vitamin C that is more stable and less irritating than ascorbic acid. According to a recent clinical study, THDA has all the capabilities of regular vitamin C, including anti-wrinkle and anti-pigment activity.
S-Palmitoylglutathione
Est. %1.5
Function
Origin
Description is coming soon
Dimethyl MEA
Est. %1.3
Function
Origin
Dimethyl MEA is a chemical compound with many names - it can also be listed as DMAE, deanol or 2-dimethylaminoethanol. It is described as a colorless liquid with a fishy smell. DMAE is added to skincare products to regulate the pH balance, but can potentially be toxic.
Palmitoyl Tripeptide-38
Est. %0.3
Function
Origin

A small synthetic peptide that increases the production of collagen, fibronectin, and hyaluronic acid in the skin. It has also been shown to reduce wrinkles in combination with other anti-aging ingredients.

Acetyl Tyrosine
Est. %0.3
Function
Origin
Acetyl tyrosine is a derivative of the amino acid tyrosine. It is used as a tanning agent in skincare, helping pigment cells (melanosomes) to produce more dark skin pigment.
Avena Sativa (Oat) Kernel Extract
Est. %0.3
Function
Origin
A beneficial extract obtained from Oat groats popular in products aimed at eczema-prone skin. It contains skin healing beta-glucan, anti-inflammatory phenolic compounds, antioxidant flavonoids, various lipids, proteins, and moisturizing amino acids.
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Macadamia Ternifolia Seed Oil
Est. %0.3
Function
Origin
An occlusive moisturizing and emollient oil extracted from macadamia nuts. It is clear and pale yellow with a pleasant nutty aroma and contains oleic and palmitoleic fatty acids, tocopherols, phytosterols, squalene, and polyphenols.
Linum Usitatissimum (Linseed) Seed Oil
Est. %0.3
Function
Origin
An emollient and occlusive fatty oil pressed from flax seeds. It is the richest source of linolenic fatty acid (it contains up to 50% of it) among vegetable oils.
Salvia Hispanica Seed Oil
Est. %0.3
Function
Origin
An oil extracted from Chia seeds. It has a unique ratio of omega-3 and omega-6 fatty acids, making it the richest source of polyunsaturated fatty acids. It also contains antioxidant phytosterols and tocopherols (vitamin E).
Silica Cetyl Silylate
Est. %0.3
Function
Origin
Description is coming soon
Ethylhexylglycerin
Est. %0.3
Function
Origin
A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Sodium Hyaluronate
Est. %0.3
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
A fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
A soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Tetrasodium Glutamate Diacetate
Est. %0.3
Function
Origin
A biodegradable chelating agent that chemically captures the heavy metal ions naturally present in water and disarms their harmful effects.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
A synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Hydroxypropyl Cyclodextrin
Est. %0.3
Function
Origin
A white crystalline powder that can reduce odors coming from other ingredients in a product.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Silica
Est. %0.3
Function
Origin
A widely used cosmetic ingredient with the same chemical composition as the sand found on beaches. A common function of silica is its ability to control viscosity. In certain chemical forms, it can effectively thicken cream-style products.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Iron Oxides (CI 77491)
Est. %0.3
Function
Origin
A red colorant also known as red iron oxide. This is an EU-approved colorant used in a wide variety of products.