Perricone MD Cold Plasma+ Advanced Serum Concentrate

Perricone MD Cold Plasma+ Advanced Serum Concentrate
4.4
/ 10
Moisturizing
8.2 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
0.1Anti-wrinkle icon/ 10
Anti-wrinkle
$$$$

Review

Results you may expect from using Perricone MD Cold Plasma+ Advanced Serum Concentrate:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Perricone MD Cold Plasma+ Advanced Serum Concentrate:

  • Moderate moisturizing. It has a moisturizing rating of 4.4 out of 10.
  • Little anti-wrinkle effect: Perricone MD Cold Plasma+ Advanced Serum Concentrate has an anti-wrinkle rating of 0.1 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

How moisturizing is it?

Quite moisturizing: Perricone MD Cold Plasma+ Advanced Serum Concentrate has a moisturizing rating of 4.4 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a very high humectancy of 8.2 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Perricone MD Cold Plasma+ Advanced Serum Concentrate has a minimal anti-wrinkle rating of 0.1 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈0.3%),
 highly effective in peelings, yet with below-average anti-wrinkle efficacy when used in leave-on skincare products.
 
Among others, Perricone MD Cold Plasma+ Advanced Serum Concentrate also contains some ingredients marketed as effective in reducing wrinkles, specifically Tetrahexyldecyl Ascorbate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Gluconate, Retinyl Palmitate, and Copper Tripeptide-1. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
8.2
6
1.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
4.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 8.2 10
8.2
6
1.3
0.3
0.3
0.3
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
4.4
Ingredient Est. % Benchmark Humectancy
6
1.3
0.3
0.3
0.3
All humectants 8.2 10
8.2
All humectants
8.2
6
1.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.1
Glycolic Acid
0.1
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
0.3
Tetrahexyldecyl Ascorbate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Gluconate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.1
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
All antioxidants 1.2 3 No
All antioxidants
1.2
Tetrahexyldecyl Ascorbate
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Sodium Hyaluronate
0.3
Copper Tripeptide-1
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
All soothing 1.2 5 No
All soothing
1.2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Isopropyl Palmitate
Est. %4
Function
Origin
An emollient ester of palmitic acid and isopropanol that gives the skin a smooth, soft, dry, non-oily after-feel. Isopropyl palmitate is listed as a common comedogenic ingredient by acne.org.
Cetearyl Alcohol
Est. %3
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Glyceryl Stearate
Est. %2
Function
Origin
An emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %1.5
Function
Origin
This surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Butylene Glycol
Est. %1.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Phosphatidylcholine
Est. %1
Function
Origin
A special emulsifying lipid used to create delivery spheres called liposomes.
Tetrahexyldecyl Ascorbate
Est. %0.3
Function
Origin
A lipid-soluble form of vitamin C that is more stable and less irritating than ascorbic acid. According to a recent clinical study, THDA has all the capabilities of regular vitamin C, including anti-wrinkle and anti-pigment activity.
Dimethyl MEA
Est. %0.3
Function
Origin
Dimethyl MEA is a chemical compound with many names - it can also be listed as DMAE, deanol or 2-dimethylaminoethanol. It is described as a colorless liquid with a fishy smell. DMAE is added to skincare products to regulate the pH balance, but can potentially be toxic.
Acetyl Hexapeptide-8
Est. %0.3
Function
Origin

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Tyrosine
Est. %0.3
Function
Origin
Description is coming soon
Glycolic Acid
Est. %0.3
Function
Origin

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
A fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Magnesium Aspartate
Est. %0.3
Function
Origin
A humectant salt of aspartic acid, a common amino acid found in the body. According to the manufacturer, magnesium aspartate in skincare products supports the supply of magnesium to skin cells.
Zinc Gluconate
Est. %0.3
Function
Origin
One of the most commonly used ingredients in anti-acne products. It is an organic salt of zinc that helps to combat microbial infections, soothes and heals inflamed pimples, and regulates hormones in the skin.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
A soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Copper Gluconate
Est. %0.3
Function
Origin
An organic salt of copper that can aid in the wound healing process. The manufacturer claims it also has soothing and anti-inflammatory properties, although this has yet to be confirmed. Copper gluconate is also a perspective anti-wrinkle ingredient.
Sodium Hyaluronate
Est. %0.3
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Retinyl Palmitate
Est. %0.3
Function
Origin
An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Echium Plantagineum Seed Oil
Est. %0.3
Function
Origin
An emollient and occlusive oil from the Purple Viper’s Bugloss plant. It contains oleic, linoleic, alpha-linolenic acids, as well as very rare polyunsaturated called stearidonic acid. It is suitable for all skin types.
Hydrolyzed Myrtus Communis Leaf Extract
Est. %0.3
Function
Origin
Description is coming soon
Copper Tripeptide-1
Est. %0.3
Function
Origin

A skin-identical, copper-binding peptide that promotes the synthesis of all structural elements in the skin.

Dimethicone
Est. %0.3
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Ceteareth-20
Est. %0.3
Function
Origin
A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Cyclopentasiloxane
Est. %0.3
Function
Origin
A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Cyclohexasiloxane
Est. %0.3
Function
Origin
A clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Polysorbate 20
Est. %0.3
Function
Origin
A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Zea Mays (Corn) Oil
Est. %0.3
Function
Origin
An occlusive moisturizing fatty oil extracted from the germ of corn grains. It is made up of linoleic, oleic, and palmitic acids, and is suitable for all skin types.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Sorbic Acid
Est. %0.3
Function
Origin
An organic acid that can be naturally found in the berries of the Mountain ash, although it is manufactured synthetically for skincare purposes. It is used as a preservative and antimicrobial agent, protecting a skincare product from spoiling.