NEOGEN Dermalogy Real Ferment Micro Serum

NEOGEN Dermalogy Real Ferment Micro Serum
5.5
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.0 Occlusivity icon Occlusivity
0.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Does NEOGEN Dermalogy Real Ferment Micro Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using NEOGEN Dermalogy Real Ferment Micro Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.5 out of 10.
  • Little anti-wrinkle effect: NEOGEN Dermalogy Real Ferment Micro Serum has an anti-wrinkle rating of 0.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Soothing: NEOGEN Dermalogy Real Ferment Micro Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: NEOGEN Dermalogy Real Ferment Micro Serum has a moisturizing rating of 5.5 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.0 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Saccharomyces Ferment Filtrate (est. ≈22.0%), Butylene Glycol (est. ≈6.0%) and Glycerin (est. ≈3.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, NEOGEN Dermalogy Real Ferment Micro Serum has a minimal anti-wrinkle rating of 0.5 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:
    • Niacinamide (est. ≈0.3%),
       one of the most effective and well-researched anti-wrinkle ingredients.
    • Ascorbic Acid (est. ≈0.3%),
       or Vitamin C, a popular anti-wrinkle ingredient, yet with average efficacy confirmed by only one study.
Among others, NEOGEN Dermalogy Real Ferment Micro Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Camellia Sinensis Leaf Extract, Adenosine, Centella Asiatica Extract, and Ubiquinone. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that NEOGEN Dermalogy Real Ferment Micro Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈0.3%), Camellia Sinensis Leaf Extract (est. ≈0.3%), Lactobacillus (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, NEOGEN Dermalogy Real Ferment Micro Serum is rich (> 5%) in soothing ingredients, particularly Bifida Ferment Lysate (est. ≈40.0%) and Saccharomyces Ferment Filtrate (est. ≈22.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
40
22
11
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Bifida Ferment Lysate
Function:
Origin:
Saccharomyces Ferment Filtrate
Function:
Origin:
Betula Alba Juice
Function:
Origin:
Butylene Glycol
Function:
Origin:
Rice Ferment Filtrate (Sake)
Function:
Origin:
Glycerin
Function:
Origin:
Cetyl Ethylhexanoate
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Aspergillus Ferment
Function:
Origin:
Dimethicone
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
Niacinamide
Function:
Origin:
Cyclohexasiloxane
Function:
Origin:
Polyacrylate-13
Function:
Origin:
Water
Function:
Origin:
Panthenol
Function:
Origin:
Dimethicone/Vinyl Dimethicone Crosspolymer
Function:
Origin:
Polyisobutene
Function:
Origin:
PEG-7 Glyceryl Cocoate
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Cetearyl Olivate
Function:
Origin:
Sorbitan Olivate
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Polysorbate 20
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Lactobacillus
Function:
Origin:
Xanthan Gum
Function:
Origin:
Sodium Polyacrylate
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Adenosine
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Tropolone
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Pichia/Resveratrol Ferment Extract
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Hydrolyzed Collagen
Function:
Origin:
Glutathione
Function:
Origin:
Ascorbic Acid
Function:
Origin:
Ubiquinone
Function:
Origin:
Thioctic Acid
Function:
Origin:
Tocopherol
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Disodium EDTA
Function:
Origin:

Ratings

All humectants
33.1
22
6
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.1
1.5
0.3
0.3
Benchmark
20
Moisturizing rating
5.5
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 33.1 10
10.0
22
6
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.1 20
1.0
1.5
0.3
0.3
Moisturizing rating
5.5
Ingredient Est. % Benchmark Humectancy
22
6
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 33.1 10
10
All humectants
33.1
22
6
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.5
0.3
0.3
All occlusives 2.1 20
1.0
All occlusives
2.1
1.5
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 0.3 0.4
2.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.5
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.5
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.3 3 Rich in antioxidants
All antioxidants
3.3
Niacinamide
0.3
Ascorbic Acid
0.3
Camellia Sinensis Leaf Extract
0.3
Lactobacillus
0.3
Sodium Hyaluronate
0.3
Tropolone
0.3
Centella Asiatica Extract
0.3
Glutathione
0.3
Ubiquinone
0.3
Thioctic Acid
0.3
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
40
22
0.3
0.3
0.3
0.3
All soothing 63.2 5 Rich in soothing
All soothing
63.2
40
22
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Bifida Ferment Lysate
Est. %40
Function
Origin
Bifida Ferment LysateA mixture of probiotic bacteria. According to the patent holder, it contains enzymes that are able to repair damaged DNA in skin cells. A single study confirms that it is able to reduce skin sensitivity.
Saccharomyces Ferment Filtrate
Est. %22
Function
Origin
Saccharomyces Ferment FiltrateA yeast mixture that contains humectant moisturizing amino acids, nucleic acids (building blocks of DNA), peptides, various minerals, and vitamins.
Betula Alba Juice
Est. %11
Function
Origin
Betula Alba Juice
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Rice Ferment Filtrate (Sake)
Est. %4
Function
Origin
Rice Ferment Filtrate (Sake)
Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Cetyl Ethylhexanoate
Est. %2
Function
Origin
Cetyl EthylhexanoateA clear, pale yellow liquid, that functions as an emollient and a solvent, meaning that it is useful for dissolving oil-soluble ingredients.
Caprylic/Capric Triglyceride
Est. %1.5
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Aspergillus Ferment
Est. %1
Function
Origin
Aspergillus Ferment
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Cyclopentasiloxane
Est. %0.3
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Cyclohexasiloxane
Est. %0.3
Function
Origin
CyclohexasiloxaneA clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.
Polyacrylate-13
Est. %0.3
Function
Origin
Polyacrylate-13A synthetic, film-forming ingredient that creates a network around other ingredients in the formula and protects them from being easily washed away.
Water
Est. %0.3
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Dimethicone/Vinyl Dimethicone Crosspolymer
Est. %0.3
Function
Origin
Dimethicone/Vinyl Dimethicone CrosspolymerThis ingredient can refer to several kinds of dimethicone crosspolymers. Like other silicones, it makes products feel slippery and non-greasy but can also increase the thickness or improve the water-resistance of a formula.
Polyisobutene
Est. %0.3
Function
Origin
PolyisobuteneA highly viscous liquid that is used in lip gloss formulations to prolong wear time and add shimmer. Polyisobutene dramatically increases the thickness of skincare products it is added to.
PEG-7 Glyceryl Cocoate
Est. %0.3
Function
Origin
PEG-7 Glyceryl Cocoate

A clear, pale yellow, oil-like emollient manufactured synthetically from coconut oil and polyethylene glycol. It is also used as an emulsifying agent.

Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
Camellia Sinensis Leaf Extract

An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.

Cetearyl Olivate
Est. %0.3
Function
Origin
Cetearyl Olivate

A multifunctional ingredient derived from plants that primarily serves as an emulsifier. Supplied as a waxy ivory-colored flake, it can also be used as an emollient and slip modifier that gives a product an overall light, silky finish.

Sorbitan Olivate
Est. %0.3
Function
Origin
Sorbitan OlivateAn ester of sorbitol (a type of sugar alcohol) and olive oil fatty acids. It is used as an emulsifying agent to stabilize oil droplets in water (or vice versa).
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Lactobacillus
Est. %0.3
Function
Origin
LactobacillusA genus of probiotic bacteria. Lactobacillus bacteria are part of the human microflora and their ferment products contain antioxidants.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Sodium Polyacrylate
Est. %0.3
Function
Origin
Sodium PolyacrylateThis white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Tropolone
Est. %0.3
Function
Origin
TropoloneA naturally occurring ingredient with unusual molecular structure that fights free radicals.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Pichia/Resveratrol Ferment Extract
Est. %0.3
Function
Origin
Pichia/Resveratrol Ferment Extract
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Hydrolyzed Collagen
Est. %0.3
Function
Origin
Hydrolyzed Collagen

A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.

Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Ascorbic Acid
Est. %0.3
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Ubiquinone
Est. %0.3
Function
Origin
UbiquinoneAlso known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Thioctic Acid
Est. %0.3
Function
Origin
Thioctic Acid
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.