Mediheal THE I.P.I Brightening Ampoule Mask Review

Mediheal THE I.P.I Brightening Ampoule Mask
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
4.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Ingredients

Mediheal THE I.P.I Brightening Ampoule Mask Ingredients

Hover to see details. On mobile? Tap for ingredient stories!

Full Ingredient List (INCI):

Water, Butylene Glycol, Propanediol, Niacinamide, Glycerin, 1,2-Hexanediol, Carbomer, Tromethamine, Betaine, Trehalose, Panthenol, Polyglyceryl-10 Laurate, Salix Alba (Willow) Bark Extract, Allantoin, Adenosine, Chamaecyparis Obtusa Leaf Extract, Disodium EDTA, Gluconic Acid, Sodium Ascorbyl Phosphate, Mandelic Acid, Capryloyl Salicylic Acid, Lactobionic Acid, Glycine, Glutamic Acid, Sodium Hyaluronate Crosspolymer, Aspartic Acid, Tranexamic Acid, Sodium Polyacrylate, Sodium Chloride, Sodium Hyaluronate, Glutathione, Serine, Histidine, Arginine, Alanine, Threonine, Proline, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Magnesium Chloride, Fullerenes, Calcium Chloride, Fragrance
Review

Does Mediheal THE I.P.I Brightening Ampoule Mask Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Mediheal THE I.P.I Brightening Ampoule Mask has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Considerable anti-wrinkle efficacy: Mediheal THE I.P.I Brightening Ampoule Mask has an anti-wrinkle rating of 4.5 out of 10, indicating a moderate ability to reduce wrinkles.
✅ Antioxidant protection

  

Key Benefits of Mediheal THE I.P.I Brightening Ampoule Mask

 
These are the key benefits you can expect from using Mediheal THE I.P.I Brightening Ampoule Mask:
 

🔵 Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Mediheal THE I.P.I Brightening Ampoule Mask is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Propanediol (est. ≈4.0%) and Niacinamide (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Considerable Anti-Wrinkle Efficacy

According to CreamScan analysis, Mediheal THE I.P.I Brightening Ampoule Mask has a moderate anti-wrinkle rating of 4.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈3.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Mediheal THE I.P.I Brightening Ampoule Mask also contains some ingredients marketed often as effective in reducing wrinkles, specifically Adenosine, Sodium Ascorbyl Phosphate, and Lactobionic Acid. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Mediheal THE I.P.I Brightening Ampoule Mask is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Mediheal THE I.P.I Brightening Ampoule Mask

 
CreamScan identified a few things to consider before adding Mediheal THE I.P.I Brightening Ampoule Mask to your skincare routine:
 

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Mediheal THE I.P.I Brightening Ampoule Mask as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Mediheal THE I.P.I Brightening Ampoule Mask

 
Here’s an overview of the pros and cons of Mediheal THE I.P.I Brightening Ampoule Mask to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Provides considerable anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
   

Summary: Mediheal THE I.P.I Brightening Ampoule Mask

 
Based on the ingredient list analysis, CreamScan AI suggests that Mediheal THE I.P.I Brightening Ampoule Mask
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
Mediheal THE I.P.I Brightening Ampoule Mask contains ingredients with solid, robust evidence of anti-wrinkle efficacy, in concentrations that may deliver a noticeable anti-wrinkle effect.
 
With its high antioxidant content, Mediheal THE I.P.I Brightening Ampoule Mask helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Mediheal THE I.P.I Brightening Ampoule Mask worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Propanediol
Function:
Origin:
Niacinamide
Function:
Origin:
Glycerin
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Carbomer
Function:
Origin:
Tromethamine
Function:
Origin:
Betaine
Function:
Origin:
Trehalose
Function:
Origin:
Panthenol
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Salix Alba (Willow) Bark Extract
Function:
Origin:
Allantoin
Function:
Origin:
Adenosine
Function:
Origin:
Chamaecyparis Obtusa Leaf Extract
Function:
Origin:
Disodium EDTA
Function:
Origin:
Gluconic Acid
Function:
Origin:
Sodium Ascorbyl Phosphate
Function:
Origin:
Mandelic Acid
Function:
Origin:
Capryloyl Salicylic Acid
Function:
Origin:
Lactobionic Acid
Function:
Origin:
Glycine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Sodium Hyaluronate Crosspolymer
Function:
Origin:
Aspartic Acid
Function:
Origin:
Tranexamic Acid
Function:
Origin:
Sodium Polyacrylate
Function:
Origin:
Sodium Chloride
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Glutathione
Function:
Origin:
Serine
Function:
Origin:
Histidine
Function:
Origin:
Arginine
Function:
Origin:
Alanine
Function:
Origin:
Threonine
Function:
Origin:
Proline
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Magnesium Chloride
Function:
Origin:
Fullerenes
Function:
Origin:
Calcium Chloride
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
19.5
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 19.5 10
10.0
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 19.5 10
10
All humectants
19.5
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
4.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Sodium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Lactobionic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
0.3
All antioxidants 3.9 3 Rich in antioxidants
All antioxidants
3.9
Niacinamide
3
Sodium Ascorbyl Phosphate
0.3
Sodium Hyaluronate
0.3
Glutathione
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
0.3
0.3
All soothing 4.2 5 No
All soothing
4.2
3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Propanediol
Est. %4
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Glycerin
Est. %2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

1,2-Hexanediol
Est. %1.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Carbomer
Est. %1.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Tromethamine
Est. %1
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Betaine
Est. %0.3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Trehalose
Est. %0.3
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Salix Alba (Willow) Bark Extract
Est. %0.3
Function
Origin
Salix Alba (Willow) Bark ExtractA potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Chamaecyparis Obtusa Leaf Extract
Est. %0.3
Function
Origin
Chamaecyparis Obtusa Leaf Extract
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Gluconic Acid
Est. %0.3
Function
Origin
Gluconic Acid
Sodium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Sodium Ascorbyl PhosphateThe most researched derivative of vitamin C. It boosts collagen synthesis, thereby improving skin structure and elasticity. SAP is effective in the treatment of inflamed acne lesions and has a weak but positive effect on pigmentation issues.
Mandelic Acid
Est. %0.3
Function
Origin
Mandelic AcidDerived from almonds, this ingredient is one of the gentlest AHAs and is used for its exfoliating and antimicrobial properties. It is particularly beneficial for acne but also helps to treat post-inflammatory hyperpigmentation.
Capryloyl Salicylic Acid
Est. %0.3
Function
Origin
Capryloyl Salicylic AcidA derivative of salicylic acid, with bigger and more lipid-soluble molecules. This makes it more powerful and safer than salicylic acid. It is used as an exfoliating and peeling agent.
Lactobionic Acid
Est. %0.3
Function
Origin
Lactobionic AcidA very gentle and non-irritating PHA derived from lactic acid. It has exfoliating and humectant properties and can improve skin elasticity.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Sodium Hyaluronate Crosspolymer
Est. %0.3
Function
Origin
Sodium Hyaluronate CrosspolymerA modified version of regular hyaluronic acid. It attracts large volumes of water, thereby making it an effective humectant moisturizing ingredient.
Aspartic Acid
Est. %0.3
Function
Origin
Aspartic AcidA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to retain water on the skin’s surface and is slightly acidic, thereby helping to balance the pH of a skincare product.
Tranexamic Acid
Est. %0.3
Function
Origin
Tranexamic AcidA synthetic amino acid that is used as an astringent to stop the bleeding from small cuts. It also has proven anti-pigment and redness-reducing effects.
Sodium Polyacrylate
Est. %0.3
Function
Origin
Sodium PolyacrylateThis white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Sodium Chloride
Est. %0.3
Function
Origin
Sodium Chloride

You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Histidine
Est. %0.3
Function
Origin
HistidineA humectant moisturizing amino acid with weak antioxidant effects that is a part of the skin’s Natural Moisturizing Factor. It can attract water to the skin’s surface and is slightly alkaline, thereby helping to balance a product's pH.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Threonine
Est. %0.3
Function
Origin
ThreonineAn essential amino acid that may play a role in collagen production. However, more research is needed in order to confirm or deny these claims.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Magnesium Chloride
Est. %0.3
Function
Origin
Magnesium ChlorideA chloride salt with a bitter taste and the ability to thicken water-in-oil emulsions.
Fullerenes
Est. %0.3
Function
Origin
Fullerenes
Calcium Chloride
Est. %0.3
Function
Origin
Calcium ChlorideA salt that can stabilize emulsions through thickening. It also serves as an astringent.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.