MediCube PDRN Pink Cica Soothing Toner Review

MediCube PDRN Pink Cica Soothing Toner
4.4
/ 10
Moisturizing
8.9 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does MediCube PDRN Pink Cica Soothing Toner Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what MediCube PDRN Pink Cica Soothing Toner has to offer:
 
  • Moderate moisturizing. It has a moisturizing rating of 4.4 out of 10.
  • Slight anti-wrinkle effect: MediCube PDRN Pink Cica Soothing Toner has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

Key Benefits of MediCube PDRN Pink Cica Soothing Toner

 
These are the key benefits you can expect from using MediCube PDRN Pink Cica Soothing Toner:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, MediCube PDRN Pink Cica Soothing Toner is quite moisturizing, with a moisturizing rating of 4.4 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a very high humectancy of 8.9 out of 10, primarily due to the high content of Gluconolactone (est. ≈3.0%) and Allantoin (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, MediCube PDRN Pink Cica Soothing Toner has a slight anti-wrinkle rating of 0.4 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈0.3%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, MediCube PDRN Pink Cica Soothing Toner also contains some ingredients often marketed as effective in reducing wrinkles, specifically Gluconolactone, Adenosine, Centella Asiatica Leaf Extract, Centella Asiatica Extract, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, and some others. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: MediCube PDRN Pink Cica Soothing Toner

 
CreamScan AI identified a few things to consider before adding MediCube PDRN Pink Cica Soothing Toner to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using MediCube PDRN Pink Cica Soothing Toner as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of MediCube PDRN Pink Cica Soothing Toner

 
Here’s an overview of the pros and cons of MediCube PDRN Pink Cica Soothing Toner to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Provides slight anti-wrinkle efficacy

Cons: 

  • Needs to be paired with occlusives to seal in humectants if used as a standalone moisturizer

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Sodium Citrate
Function:
Origin:
Citric Acid
Function:
Origin:
Gluconolactone
Function:
Origin:
Allantoin
Function:
Origin:
Disodium EDTA
Function:
Origin:
Xylitol
Function:
Origin:
Niacinamide
Function:
Origin:
Adenosine
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Polyglyceryl-4 Laurate
Function:
Origin:
Caprylyl/Capryl Glucoside
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Sodium DNA
Function:
Origin:
Cyanocobalamin
Function:
Origin:
Centella Asiatica Leaf Extract
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Zea Mays (Corn) Leaf Extract
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Glycine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Arginine
Function:
Origin:
Copper Tripeptide-1
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Palmitoyl Pentapeptide-4
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Carica Papaya (Papaya) Fruit Extract
Function:
Origin:
Pyrus Malus (Apple) Fruit Extract
Function:
Origin:
Prunus Mume Fruit Extract
Function:
Origin:

Ratings

All humectants
8.9
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
4.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 8.9 10
8.9
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
4.4
Ingredient Est. % Benchmark Humectancy
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 8.9 10
8.9
All humectants
8.9
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 0.3 0.4
n/a
- 3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.4
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Gluconolactone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Centella Asiatica Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Pentapeptide-4
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 2.1 3 No
All antioxidants
2.1
Niacinamide
0.3
Centella Asiatica Leaf Extract
0.3
Centella Asiatica Extract
0.3
Sodium Hyaluronate
0.3
Copper Tripeptide-1
0.3
Carica Papaya (Papaya) Fruit Extract
0.3
Pyrus Malus (Apple) Fruit Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 3.8 5 No
All soothing
3.8
2
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Sodium Citrate
Est. %6
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Citric Acid
Est. %4
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Gluconolactone
Est. %3
Function
Origin
GluconolactoneA PHA derived from glucose. It has exfoliating and humectant properties and acts as a penetration enhancer for other ingredients. It has also been shown to assist in the treatment of acne and the prevention of photoaging.
Allantoin
Est. %2
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Xylitol
Est. %0.3
Function
Origin
XylitolAn organic compound that is most well-known for its use as a sweetener that also protects your teeth from cavities. Xylitol is used in skincare as a moisturizing humectant and has been shown to improve the protective barrier function of the skin.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Glycerin
Est. %0.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Polyglyceryl-4 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-4 Laurate
Caprylyl/Capryl Glucoside
Est. %0.3
Function
Origin
Caprylyl/Capryl GlucosideA naturally-derived surfactant used for gentle cleansing and foam-boosting when combined with other surfactants.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Sodium DNA
Est. %0.3
Function
Origin
Sodium DNA
Cyanocobalamin
Est. %0.3
Function
Origin
CyanocobalaminA product of bacterial fermentation that may have soothing and rejuvenating skin effects.
Centella Asiatica Leaf Extract
Est. %0.3
Function
Origin
Centella Asiatica Leaf ExtractA well-researched soothing, wound-healing, and promising anti-aging extract that is obtained from the leaves of the Gotu Kola.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Zea Mays (Corn) Leaf Extract
Est. %0.3
Function
Origin
Zea Mays (Corn) Leaf Extract
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Copper Tripeptide-1
Est. %0.3
Function
Origin
Copper Tripeptide-1

A skin-identical, copper-binding peptide that promotes the synthesis of all structural elements in the skin.

Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Palmitoyl Pentapeptide-4
Est. %0.3
Function
Origin
Palmitoyl Pentapeptide-4

A famous synthetically made peptide that works as a signal peptide, telling skin cells to create more collagen and other structural proteins. It has been clinically tested and found to be effective at reducing fine wrinkles.

Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Carica Papaya (Papaya) Fruit Extract
Est. %0.3
Function
Origin
Carica Papaya (Papaya) Fruit ExtractA soothing extract obtained derived from the papaya fruit. It contains a skin softening and mildly exfoliating enzyme called papain, as well as various anti-inflammatory and antioxidant compounds that can assist in the wound healing process.
Pyrus Malus (Apple) Fruit Extract
Est. %0.3
Function
Origin
Pyrus Malus (Apple) Fruit ExtractAn extract derived from apple fruit that has humectant moisturizing and antioxidant properties, as well as gentle anti-pigment effects. It contains humectant sugars, anti-pigment organic acids, and flavonoids.
Prunus Mume Fruit Extract
Est. %0.3
Function
Origin
Prunus Mume Fruit Extract