MediCube Age-R Glutathione Glow Serum Review

MediCube Age-R Glutathione Glow Serum
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.4 Occlusivity icon Occlusivity
4.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does MediCube Age-R Glutathione Glow Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what MediCube Age-R Glutathione Glow Serum has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.2 out of 10.
  • Considerable anti-wrinkle efficacy: MediCube Age-R Glutathione Glow Serum has an anti-wrinkle rating of 4.5 out of 10, indicating a moderate ability to reduce wrinkles.
  • Antioxidant protection.

Key Benefits of MediCube Age-R Glutathione Glow Serum

 
These are the key benefits you can expect from using MediCube Age-R Glutathione Glow Serum:
 

Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, MediCube Age-R Glutathione Glow Serum is quite moisturizing, with a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.4 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%), PEG-8 (est. ≈4.0%) and Niacinamide (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Considerable Anti-Wrinkle Efficacy

According to CreamScan analysis, MediCube Age-R Glutathione Glow Serum has a moderate anti-wrinkle rating of 4.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈3.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, MediCube Age-R Glutathione Glow Serum also contains contains Adenosine and Beta-Glucan, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that MediCube Age-R Glutathione Glow Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of MediCube Age-R Glutathione Glow Serum

 
Here’s an overview of the pros and cons of MediCube Age-R Glutathione Glow Serum to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Provides considerable anti-wrinkle efficacy thanks to Niacinamide
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • We couldn't find any

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
PEG-8
Function:
Origin:
Niacinamide
Function:
Origin:
Butylene Glycol
Function:
Origin:
Methylpropanediol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Betaine
Function:
Origin:
Glycereth-26
Function:
Origin:
Bis-PEG-18 Methyl Ether Dimethyl Silane
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Bifida Ferment Lysate
Function:
Origin:
Methyl Gluceth-20
Function:
Origin:
Panthenol
Function:
Origin:
Squalane
Function:
Origin:
Glucosylrutin
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Carbomer
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Tromethamine
Function:
Origin:
Xanthan Gum
Function:
Origin:
Propanediol
Function:
Origin:
Flavor (Aroma)
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Glutathione
Function:
Origin:
Adenosine
Function:
Origin:
Ceramide NP
Function:
Origin:
Sodium Phytate
Function:
Origin:
Benzyl Glycol
Function:
Origin:
Hydrolyzed Glycosaminoglycans
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Dextrin
Function:
Origin:
Theobroma Cacao (Cocoa) Extract
Function:
Origin:
Beta-Glucan
Function:
Origin:
Cyanocobalamin
Function:
Origin:
Sodium Hyaluronate Crosspolymer
Function:
Origin:
Tocopherol
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Hydroxypropyltrimonium Hyaluronate
Function:
Origin:
Soluble Collagen
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:
Sodium Stearoyl Glutamate
Function:
Origin:

Ratings

All humectants
21.7
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.9
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 21.7 10
10.0
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.9 20
0.4
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 21.7 10
10
All humectants
21.7
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
All occlusives 0.9 20
0.4
All occlusives
0.9
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
n/a
- 0.3 -
n/a
- 0.3 -
Total
4.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.4 3 Rich in antioxidants
All antioxidants
5.4
Niacinamide
3
Glucosylrutin
0.3
Glutathione
0.3
Sodium Hyaluronate
0.3
Theobroma Cacao (Cocoa) Extract
0.3
Beta-Glucan
0.3
Tocopherol
0.3
Hydrolyzed Hyaluronic Acid
0.3
Hyaluronic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
0.3
0.3
All soothing 4.2 5 No
All soothing
4.2
3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

PEG-8
Est. %4
Function
Origin
PEG-8A synthetic liquid that serves as a humectant. It also works as a solvent because of its ability to dissolve a wide range of ingredients.
Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Butylene Glycol
Est. %2
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Methylpropanediol
Est. %1.5
Function
Origin
MethylpropanediolMethylpropanediol is a unique glycol that contains two primary hydroxyl groups. That makes methylpropanediol a powerful humectant and an excellent solvent.
1,2-Hexanediol
Est. %1.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Betaine
Est. %1
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Glycereth-26
Est. %0.3
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Bis-PEG-18 Methyl Ether Dimethyl Silane
Est. %0.3
Function
Origin
Bis-PEG-18 Methyl Ether Dimethyl SilaneA silicone with the unusual trait of being able to disperse in water. It moisturizes the skin as a humectant and leaves a soft and smooth after-feel. This ingredient also has foam-boosting properties.
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Bifida Ferment Lysate
Est. %0.3
Function
Origin
Bifida Ferment LysateA mixture of probiotic bacteria. According to the patent holder, it contains enzymes that are able to repair damaged DNA in skin cells. A single study confirms that it is able to reduce skin sensitivity.
Methyl Gluceth-20
Est. %0.3
Function
Origin
Methyl Gluceth-20A humectant synthetically derived from glucose. It takes on the form of a clear, syrupy liquid.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Squalane
Est. %0.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Glucosylrutin
Est. %0.3
Function
Origin
Glucosylrutin
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Propanediol
Est. %0.3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Flavor (Aroma)
Est. %0.3
Function
Origin
Flavor (Aroma)Under trade secret law, manufacturers have the right not to disclose what exactly went into the flavor and use the unspecific word 'flavor' instead. Flavor is added to products that have the potential to be consumed, such as lipsticks.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Sodium Phytate
Est. %0.3
Function
Origin
Sodium PhytateSodium phytate is a chelating agent that serves to remove heavy metal ions from water. Removing metal ions helps other ingredients, such as antioxidants and preservatives, to perform better and keep products from separating.
Benzyl Glycol
Est. %0.3
Function
Origin
Benzyl Glycol
Hydrolyzed Glycosaminoglycans
Est. %0.3
Function
Origin
Hydrolyzed Glycosaminoglycans
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Dextrin
Est. %0.3
Function
Origin
DextrinA partially hydrolyzed potato starch, most commonly used as a viscosity controlling and binding agent. When dispersed into water, it can create textures ranging from a thick paste to a soft gel.
Theobroma Cacao (Cocoa) Extract
Est. %0.3
Function
Origin
Theobroma Cacao (Cocoa) Extract

An extract from cocoa beans or cocoa powder with lots of beneficial compounds such as stimulant caffeine, antioxidant and astringent flavanols, and tannins – which are responsible for its bitter taste.

Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Cyanocobalamin
Est. %0.3
Function
Origin
CyanocobalaminA product of bacterial fermentation that may have soothing and rejuvenating skin effects.
Sodium Hyaluronate Crosspolymer
Est. %0.3
Function
Origin
Sodium Hyaluronate CrosspolymerA modified version of regular hyaluronic acid. It attracts large volumes of water, thereby making it an effective humectant moisturizing ingredient.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Hydroxypropyltrimonium Hyaluronate
Est. %0.3
Function
Origin
Hydroxypropyltrimonium Hyaluronate
Soluble Collagen
Est. %0.3
Function
Origin
Soluble CollagenA protein obtained from farm or marine animals. Collagen molecules are too big to penetrate the skin so when they are applied via a skincare product they sit on top of the skin and act as humectant moisturizers.
Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.
Sodium Stearoyl Glutamate
Est. %0.3
Function
Origin
Sodium Stearoyl GlutamateA useful ingredient for both cleansing and emulsifying purposes. It is a powerful agent for washing away dirt and oils from the skin.