iS Clinical Youth Intensive Creme

iS Clinical Youth Intensive Creme
5.6
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.3 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does iS Clinical Youth Intensive Creme work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using iS Clinical Youth Intensive Creme:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.6 out of 10.
  • Some anti-wrinkle efficacy: iS Clinical Youth Intensive Creme has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, iS Clinical Youth Intensive Creme is quite moisturizing, with a moisturizing rating of 5.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.3 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Hyaluronic Acid (est. ≈2.5%), Glycerin (est. ≈2.2%) and Urea (est. ≈2.1%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical Youth Intensive Creme has a slight anti-wrinkle rating of 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Asiaticoside (est. ≈0.3%), 
 derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 27 participants (Lee et al.). This study demonstrated that a cream containing 0.1% asiaticoside reduced the average wrinkle depth by 8% after 12 weeks of use, compared to a vehicle (the same formulation without asiaticoside).
 
Among others, iS Clinical Youth Intensive Creme also contains some ingredients often marketed as effective in reducing wrinkles, specifically Tripeptide-1, Tetrahexyldecyl Ascorbate, Dipalmitoyl Hydroxyproline, Retinyl Palmitate, Asiatic Acid, Madecassic Acid, Ascorbyl Palmitate, Soy Isoflavones, and some others. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that iS Clinical Youth Intensive Creme is rich (> 3%) in antioxidants, specifically Hyaluronic Acid (est. ≈2.5%) and Vaccinium Myrtillus Fruit/Leaf Extract (est. ≈2.3%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
70
2.5
2.4
2.3
2.2
2.1
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Vaccinium Myrtillus Fruit/Leaf Extract
Function:
Origin:
Glycerin
Function:
Origin:
Urea
Function:
Origin:
Glucose
Function:
Origin:
Guanidine HCl
Function:
Origin:
Tripeptide-1
Function:
Origin:
Saccharum Officinarum (Sugarcane) Extract
Function:
Origin:
Salix Alba (Willow) Bark Extract
Function:
Origin:
Glyceryl Dilaurate
Function:
Origin:
Tetrahexyldecyl Ascorbate
Function:
Origin:
Dimethicone
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Dipalmitoyl Hydroxyproline
Function:
Origin:
Superoxide Dismutase
Function:
Origin:
Ormenis Multicaulis Oil
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Peel Oil
Function:
Origin:
Phospholipids
Function:
Origin:
Retinyl Palmitate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Pantothenic Acid
Function:
Origin:
Acer Saccharum (Sugar Maple) Extract
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Fruit Extract
Function:
Origin:
Citrus Limon (Lemon) Fruit Extract
Function:
Origin:
Asiaticoside
Function:
Origin:
Asiatic Acid
Function:
Origin:
Madecassic Acid
Function:
Origin:
Ascorbyl Palmitate
Function:
Origin:
PEG-8/SMDI Copolymer
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Soy Isoflavones
Function:
Origin:
Ethylbisiminomethylguaiacol Manganese Chloride
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Ethylhexyl Palmitate
Function:
Origin:
Silica Dimethyl Silylate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Ceteareth-20
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Carbomer
Function:
Origin:
Xanthan Gum
Function:
Origin:
PVP
Function:
Origin:
Panthenol
Function:
Origin:
Triethanolamine
Function:
Origin:
Disodium EDTA
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Methylglucoside Phosphate
Function:
Origin:
Copper Lysinate/Prolinate
Function:
Origin:

Ratings

All humectants
10.9
2.5
2.2
2.1
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.7
2.4
0.3
Benchmark
20
Moisturizing rating
5.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.9 10
10.0
2.5
2.2
2.1
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.7 20
1.3
2.4
0.3
Moisturizing rating
5.6
Ingredient Est. % Benchmark Humectancy
2.5
2.2
2.1
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 10.9 10
10
All humectants
10.9
2.5
2.2
2.1
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2.4
0.3
All occlusives 2.7 20
1.3
All occlusives
2.7
2.4
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
3 /10 0.1 0.3 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tetrahexyldecyl Ascorbate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dipalmitoyl Hydroxyproline
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ascorbyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Soy Isoflavones
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Lysinate/Prolinate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
2.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 7.8 3 Rich in antioxidants
All antioxidants
7.8
Hyaluronic Acid
2.5
Vaccinium Myrtillus Fruit/Leaf Extract
2.3
Asiaticoside
0.3
Saccharum Officinarum (Sugarcane) Extract
0.3
Tetrahexyldecyl Ascorbate
0.3
Superoxide Dismutase
0.3
Tocopheryl Acetate
0.3
Acer Saccharum (Sugar Maple) Extract
0.3
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Ascorbyl Palmitate
0.3
Soy Isoflavones
0.3
Ethylbisiminomethylguaiacol Manganese Chloride
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Hyaluronic Acid
Est. %2.5
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Caprylic/Capric Triglyceride
Est. %2.4
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Vaccinium Myrtillus Fruit/Leaf Extract
Est. %2.3
Function
Origin
Vaccinium Myrtillus Fruit/Leaf ExtractDerived from the berries and leaves of the bilberry plant, this powerful antioxidant, astringent, and refreshing extract is rich in anthocyanins, flavonoids, and tannins.
Glycerin
Est. %2.2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Urea
Est. %2.1
Function
Origin
UreaUrea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Glucose
Est. %2
Function
Origin
GlucoseA simple sugar that is also one of two components of sucrose, or table sugar. It is used as a humectant in skincare products. Glucose is also used to flavor lip care cosmetics because of its mildly sweet taste.
Guanidine HCl
Est. %1.5
Function
Origin
Guanidine HCl
Tripeptide-1
Est. %0.3
Function
Origin
Tripeptide-1

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Saccharum Officinarum (Sugarcane) Extract
Est. %0.3
Function
Origin
Saccharum Officinarum (Sugarcane) ExtractAn antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Salix Alba (Willow) Bark Extract
Est. %0.3
Function
Origin
Salix Alba (Willow) Bark ExtractA potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Glyceryl Dilaurate
Est. %0.3
Function
Origin
Glyceryl Dilaurate
Tetrahexyldecyl Ascorbate
Est. %0.3
Function
Origin
Tetrahexyldecyl AscorbateA lipid-soluble form of vitamin C that is more stable and less irritating than ascorbic acid. According to a recent clinical study, THDA has all the capabilities of regular vitamin C, including anti-wrinkle and anti-pigment activity.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Dipalmitoyl Hydroxyproline
Est. %0.3
Function
Origin
Dipalmitoyl HydroxyprolineAn amino acid derivative. It helps with skin moisturization and may have wrinkle-reducing effects.
Superoxide Dismutase
Est. %0.3
Function
Origin
Superoxide Dismutase
Ormenis Multicaulis Oil
Est. %0.3
Function
Origin
Ormenis Multicaulis OilA fragrant essential oil isolated from the flowers of the Moroccan chamomile. The scent may vary from camphoraceous to fruity or balsamic, depending on the harvest location.
Citrus Aurantium Dulcis (Orange) Peel Oil
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Peel Oil

An essential oil derived from the peels of the sweet orange. It is commonly used as a fragrance because of its pleasant, citrusy scent. The main constituent of the essential oil is limonene (up to 96%).

Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Retinyl Palmitate
Est. %0.3
Function
Origin
Retinyl PalmitateAn esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Pantothenic Acid
Est. %0.3
Function
Origin
Pantothenic AcidAlso known as vitamin B5, this ingredient helps to restore healthy moisturization of the skin and is essential for good skin health. Due to poor stability and skin penetration, panthenol is usually preferred over pantothenic acid.
Acer Saccharum (Sugar Maple) Extract
Est. %0.3
Function
Origin
Acer Saccharum (Sugar Maple) ExtractAn antioxidant extract from sugar maple bark and sap – the same sweet sap used to make maple syrup. It has a faint vanilla smell and is used in skincare for its exfoliating properties. This is because of the small sugar crystals present in the extract.
Citrus Aurantium Dulcis (Orange) Fruit Extract
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Fruit Extract

An extract from the fruit of the sweet orange. It contains fragrant sweet orange essential oil, high amounts of antioxidant flavonoids (mainly hesperidin), and carotenoids – which give it the orange color.

Citrus Limon (Lemon) Fruit Extract
Est. %0.3
Function
Origin
Citrus Limon (Lemon) Fruit Extract

A fragrant extract from lemon peels that contains various antioxidant flavonoids, organic acids, and limonoids – which are currently under investigation as potential anti-wrinkle and anti-pigment compounds.

Asiaticoside
Est. %0.3
Function
Origin
Asiaticoside

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Asiatic Acid
Est. %0.3
Function
Origin
Asiatic AcidA compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.
Madecassic Acid
Est. %0.3
Function
Origin
Madecassic AcidAn isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
Ascorbyl Palmitate
Est. %0.3
Function
Origin
Ascorbyl PalmitateA form of vitamin C derived from ascorbic acid and palmitic acid. It is more stable and less irritating than ascorbic acid. Unfortunately, Ascorbyl Palmitate lacks the studies to prove its anti-wrinkle efficacy.
PEG-8/SMDI Copolymer
Est. %0.3
Function
Origin
PEG-8/SMDI Copolymer
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Soy Isoflavones
Est. %0.3
Function
Origin
Soy IsoflavonesBioactive compounds isolated from soybeans. They act as phytoestrogens to support collagen production in aging skin.
Ethylbisiminomethylguaiacol Manganese Chloride
Est. %0.3
Function
Origin
Ethylbisiminomethylguaiacol Manganese Chloride
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Ethylhexyl Palmitate
Est. %0.3
Function
Origin
Ethylhexyl PalmitateA rich emollient without the oily after-feel, making it a popular replacement for mineral oil. It is derived from natural sources such as palm oil and palm kernel oil. Ethylhexyl palmitate is listed as a common comedogenic ingredient by acne.org.
Silica Dimethyl Silylate
Est. %0.3
Function
Origin
Silica Dimethyl SilylateA synthetic 'filler' powder primarily used as a formula helper. It is added in skincare products to adjust their consistency and thickness.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Ceteareth-20
Est. %0.3
Function
Origin
Ceteareth-20A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
PVP
Est. %0.3
Function
Origin
PVPAn excellent film-former used in hairsprays, peel-off masks, and even some self-tanning products. These films are strong and hold onto the skin.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Triethanolamine
Est. %0.3
Function
Origin
TriethanolamineA clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Methylglucoside Phosphate
Est. %0.3
Function
Origin
Methylglucoside PhosphateA derivative of glucose. It is allegedly an activated form of glucose that may be able to serve as an energy source to the skin, although this claim has not been supported by any research.
Copper Lysinate/Prolinate
Est. %0.3
Function
Origin
Copper Lysinate/ProlinateA complex of copper and two amino acids. It may stimulate the production of collagen in the skin because of the supply of copper, thus resulting in anti-wrinkle effects. This, however, has not been confirmed by studies.