iS Clinical Reparative Moisture Emulsion

iS Clinical Reparative Moisture Emulsion
6.3
/ 10
Moisturizing
9.2 Humectancy icon Humectancy
3.4 Occlusivity icon Occlusivity
Rich
in Antioxidants

Review

Results you may expect from using iS Clinical Reparative Moisture Emulsion:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using iS Clinical Reparative Moisture Emulsion:

  • Significant moisturizing. It has a moisturizing rating of 6.3 out of 10.
  • Antioxidant protection.

How moisturizing is it?

Highly moisturizing: iS Clinical Reparative Moisture Emulsion has a moisturizing rating of 6.3 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a very high humectancy of 9.2 out of 10, primarily due to the substantial concentration of Sodium Hyaluronate (est. ≈2.5%) and Glycerin (est. ≈2.4%), and a moderate occlusivity of 3.4 out of 10, mainly due to the significant content of Squalane (est. ≈2.3%) and Caprylic/Capric Triglyceride (est. ≈2.2%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical Reparative Moisture Emulsion has a zero anti-wrinkle rating.

It contains some ingredients marketed as effective in reducing wrinkles, specifically Haberlea Rhodopensis Leaf Extract, Dipalmitoyl Hydroxyproline, Tripeptide-10 Citrulline, Tripeptide-1, Retinyl Palmitate, and Ascorbyl Palmitate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that iS Clinical Reparative Moisture Emulsion is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈2.5%) and Tocopherol (est. ≈2.1%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
75
Water
2.5
Sodium Hyaluronate
2.4
Glycerin
2.3
Squalane
2.2
Caprylic/Capric Triglyceride
2.1
Tocopherol
2
Panthenyl Triacetate
1.5
Ethyl Linoleate
1.3
Butylene Glycol
1
Acetyl Tyrosine
0.3
Proline
0.3
Lecithin
0.3
Glycosaminoglycans
0.3
Beta Vulgaris (Beet) Root Extract
0.3
Haberlea Rhodopensis Leaf Extract
0.3
Xanthan Gum
0.3
Carbomer
0.3
Triethanolamine
0.3
Urea
0.3
Glucose
0.3
Guanidine HCl
0.3
Cetearyl Alcohol
0.3
Ceteareth-20
0.3
Dimethicone
0.3
Yeast Extract
0.3
Dipalmitoyl Hydroxyproline
0.3
Cyclomethicone
0.3
Hydrolyzed Vegetable Protein
0.3
Hydrolyzed Soy Protein
0.3
Tripeptide-10 Citrulline
0.3
Tripeptide-1
0.3
Polysorbate 40
0.3
Superoxide Dismutase
0.3
PVP
0.3
Panthenol
0.3
Phospholipids
0.3
Retinyl Palmitate
0.3
Tocopheryl Acetate
0.3
Ascorbyl Palmitate
0.3
Calcium Pantothenate
0.3
Ethylbisiminomethylguaiacol Manganese Chloride
0.3
1,2-Hexanediol
0.3
Caprylyl Glycol
0.3
Disodium EDTA
Est. %
Water
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Glycerin
Function:
Origin:
Squalane
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Tocopherol
Function:
Origin:
Panthenyl Triacetate
Function:
Origin:
Ethyl Linoleate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Acetyl Tyrosine
Function:
Origin:
Proline
Function:
Origin:
Lecithin
Function:
Origin:
Glycosaminoglycans
Function:
Origin:
Beta Vulgaris (Beet) Root Extract
Function:
Origin:
Haberlea Rhodopensis Leaf Extract
Function:
Origin:
Xanthan Gum
Function:
Origin:
Carbomer
Function:
Origin:
Triethanolamine
Function:
Origin:
Urea
Function:
Origin:
Glucose
Function:
Origin:
Guanidine HCl
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Ceteareth-20
Function:
Origin:
Dimethicone
Function:
Origin:
Yeast Extract
Function:
Origin:
Dipalmitoyl Hydroxyproline
Function:
Origin:
Cyclomethicone
Function:
Origin:
Hydrolyzed Vegetable Protein
Function:
Origin:
Hydrolyzed Soy Protein
Function:
Origin:
Tripeptide-10 Citrulline
Function:
Origin:
Tripeptide-1
Function:
Origin:
Polysorbate 40
Function:
Origin:
Superoxide Dismutase
Function:
Origin:
PVP
Function:
Origin:
Panthenol
Function:
Origin:
Phospholipids
Function:
Origin:
Retinyl Palmitate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Ascorbyl Palmitate
Function:
Origin:
Calcium Pantothenate
Function:
Origin:
Ethylbisiminomethylguaiacol Manganese Chloride
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Disodium EDTA
Function:
Origin:

Ratings

All humectants
9.2
2.5
2.4
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
6.9
2.3
2.2
2.1
0.3
Benchmark
20
Moisturizing rating
6.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.2 10
9.2
2.5
2.4
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 6.9 20
3.4
2.3
2.2
2.1
0.3
Moisturizing rating
6.3
Ingredient Est. % Benchmark Humectancy
2.5
2.4
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 9.2 10
9.2
All humectants
9.2
2.5
2.4
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2.3
2.2
2.1
0.3
All occlusives 6.9 20
3.4
All occlusives
6.9
2.3
2.2
2.1
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Haberlea Rhodopensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dipalmitoyl Hydroxyproline
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-10 Citrulline
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ascorbyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
2.1
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.1 3 Rich in antioxidants
All antioxidants
6.1
Sodium Hyaluronate
2.5
Tocopherol
2.1
Beta Vulgaris (Beet) Root Extract
0.3
Superoxide Dismutase
0.3
Tocopheryl Acetate
0.3
Ascorbyl Palmitate
0.3
Ethylbisiminomethylguaiacol Manganese Chloride
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Sodium Hyaluronate
Est. %2.5
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Glycerin
Est. %2.4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Squalane
Est. %2.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Caprylic/Capric Triglyceride
Est. %2.2
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Tocopherol
Est. %2.1
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Panthenyl Triacetate
Est. %2
Function
Origin
Panthenyl Triacetate
Ethyl Linoleate
Est. %1.5
Function
Origin
Ethyl Linoleate
Butylene Glycol
Est. %1.3
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Acetyl Tyrosine
Est. %1
Function
Origin
Acetyl TyrosineAcetyl tyrosine is a derivative of the amino acid tyrosine. It is used as a tanning agent in skincare, helping pigment cells (melanosomes) to produce more dark skin pigment.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Glycosaminoglycans
Est. %0.3
Function
Origin
GlycosaminoglycansA blanket term used for the structural polysaccharides of the skin, such as hyaluronic acid and chondroitin. They add to a skincare product's film-forming and water-binding properties.
Beta Vulgaris (Beet) Root Extract
Est. %0.3
Function
Origin
Beta Vulgaris (Beet) Root ExtractA purple-red extract with antioxidant activity that is obtained from red beetroot.
Haberlea Rhodopensis Leaf Extract
Est. %0.3
Function
Origin
Haberlea Rhodopensis Leaf ExtractA prospective anti-wrinkle extract derived from a rare plant – the Orpheus flower. Studies have shown that it increases skin elasticity and promotes collagen production. It also contains moisturizing polysaccharides.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Triethanolamine
Est. %0.3
Function
Origin
TriethanolamineA clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Urea
Est. %0.3
Function
Origin
UreaUrea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Glucose
Est. %0.3
Function
Origin
GlucoseA simple sugar that is also one of two components of sucrose, or table sugar. It is used as a humectant in skincare products. Glucose is also used to flavor lip care cosmetics because of its mildly sweet taste.
Guanidine HCl
Est. %0.3
Function
Origin
Guanidine HCl
Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Ceteareth-20
Est. %0.3
Function
Origin
Ceteareth-20A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Yeast Extract
Est. %0.3
Function
Origin
Yeast ExtractAlso labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
Dipalmitoyl Hydroxyproline
Est. %0.3
Function
Origin
Dipalmitoyl HydroxyprolineAn amino acid derivative. It helps with skin moisturization and may have wrinkle-reducing effects.
Cyclomethicone
Est. %0.3
Function
Origin
CyclomethiconeA blend of emollient silicones that leaves a smooth and non-greasy after-feel. Unlike other types of oils, it does not leave any residue on the skin, which is part of what makes it so popular.
Hydrolyzed Vegetable Protein
Est. %0.3
Function
Origin
Hydrolyzed Vegetable ProteinA blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Hydrolyzed Soy Protein
Est. %0.3
Function
Origin
Hydrolyzed Soy ProteinA mixture of proteins obtained from soybeans. It can have many different functions depending on the manufacturer, although it is most commonly used in skincare products as a humectant moisturizing ingredient.
Tripeptide-10 Citrulline
Est. %0.3
Function
Origin
Tripeptide-10 CitrullineA synthetically made peptide that controls the proper formation of collagen strands in the skin. It was tested in a clinical trial and showed increased skin flexibility and collagen-repair activity.
Tripeptide-1
Est. %0.3
Function
Origin
Tripeptide-1

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Polysorbate 40
Est. %0.3
Function
Origin
Polysorbate 40One of a series of emulsifiers/surfactants that is standard in many creams or lotions. High amounts of polysorbates can feel sticky, but they are often paired with other emulsifiers to better stabilize products.
Superoxide Dismutase
Est. %0.3
Function
Origin
Superoxide Dismutase
PVP
Est. %0.3
Function
Origin
PVPAn excellent film-former used in hairsprays, peel-off masks, and even some self-tanning products. These films are strong and hold onto the skin.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Retinyl Palmitate
Est. %0.3
Function
Origin
Retinyl PalmitateAn esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Ascorbyl Palmitate
Est. %0.3
Function
Origin
Ascorbyl PalmitateA form of vitamin C derived from ascorbic acid and palmitic acid. It is more stable and less irritating than ascorbic acid. Unfortunately, Ascorbyl Palmitate lacks the studies to prove its anti-wrinkle efficacy.
Calcium Pantothenate
Est. %0.3
Function
Origin
Calcium PantothenateA vitamin B5 derivative that reduces static buildup on the skin.
Ethylbisiminomethylguaiacol Manganese Chloride
Est. %0.3
Function
Origin
Ethylbisiminomethylguaiacol Manganese Chloride
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.