Institut Esthederm Cellular Concentrate Fundamental Serum Review

Institut Esthederm Cellular Concentrate Fundamental Serum
6.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
2.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Review

Does Institut Esthederm Cellular Concentrate Fundamental Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Institut Esthederm Cellular Concentrate Fundamental Serum has to offer:
 
✅ Significant moisturizing. It has a moisturizing rating of 6.0 out of 10.
✅ Antioxidant protection

  

Key Benefits of Institut Esthederm Cellular Concentrate Fundamental Serum

 
These are the key benefits you can expect from using Institut Esthederm Cellular Concentrate Fundamental Serum:
 

🔵 Lightweight Moisturizer Perfect for Combination and Oily Skin

According to CreamScan analysis, Institut Esthederm Cellular Concentrate Fundamental Serum is highly moisturizing, with a moisturizing rating of 6.0 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 2.0 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%).

This type of moisturizer is ideal for people with combination and oily skin who want maximum hydration in a relatively lightweight, non-greasy formula. It combines a significant amount of humectants with a limited amount of occlusive ingredients to boost moisturizing efficacy without feeling too heavy.

This product may also be a good choice for people with normal skin who prefer fast-absorbing textures, as it balances significant moisturizing potential with a relatively lightweight texture.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to combination and oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Institut Esthederm Cellular Concentrate Fundamental Serum is rich (> 3%) in antioxidants, specifically Tocopheryl Acetate (est. ≈1.5%), Mannitol (est. ≈1.3%), Sodium Hyaluronate (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Institut Esthederm Cellular Concentrate Fundamental Serum

 
CreamScan AI identified a few things to consider before adding Institut Esthederm Cellular Concentrate Fundamental Serum to your skincare routine:
 

⚠️ Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Institut Esthederm Cellular Concentrate Fundamental Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Acetyl Tetrapeptide-9 and Soy Isoflavones, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.

Therefore, these ingredients do not generate the anti-wrinkle rating.

📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Institut Esthederm Cellular Concentrate Fundamental Serum

 
Here’s an overview of the pros and cons of Institut Esthederm Cellular Concentrate Fundamental Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing perfect for combination and oily skin
✅ Also a good choice for people with normal skin who prefer fast-absorbing textures
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ Questionable anti-wrinkle efficacy
   

Summary: Institut Esthederm Cellular Concentrate Fundamental Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Institut Esthederm Cellular Concentrate Fundamental Serum
, when used alone, delivers lightweight, humectant-rich moisturizing, perfect for combination and oily skin. It's also a great option for those with normal skin who prefer fast-absorbing textures. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
With its high antioxidant content, Institut Esthederm Cellular Concentrate Fundamental Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Institut Esthederm Cellular Concentrate Fundamental Serum worth noting.
 
If one of your main reasons for considering Institut Esthederm Cellular Concentrate Fundamental Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, its anti-wrinkle efficacy is questionable. None of the ingredients in this product provide substantial evidence of their anti-wrinkle efficacy according to CreamScan Research Evaluation Standards.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Dimethicone
Function:
Origin:
Caprylic Acid
Function:
Origin:
Sodium Polyacrylate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Mannitol
Function:
Origin:
Propylene Glycol
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Butylene Glycol
Function:
Origin:
Chlorphenesin
Function:
Origin:
Fomes Officinalis (Mushroom) Extract
Function:
Origin:
Trideceth-6
Function:
Origin:
Creatine
Function:
Origin:
Disodium EDTA
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Laminaria Ochroleuca Extract
Function:
Origin:
PEG/PPG-18/18 Dimethicone
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Laminaria Saccharina Extract
Function:
Origin:
Rhamnose
Function:
Origin:
Carnosine
Function:
Origin:
Disodium Adenosine Triphosphate
Function:
Origin:
Methylparaben
Function:
Origin:
Laminaria Digitata Extract
Function:
Origin:
Alcohol
Function:
Origin:
PEG-40 Hydrogenated Castor Oil
Function:
Origin:
Acetyl Tetrapeptide-9
Function:
Origin:
Polysorbate 80
Function:
Origin:
Plankton Extract
Function:
Origin:
Propylparaben
Function:
Origin:
Lecithin
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Superoxide Dismutase
Function:
Origin:
Tromethamine
Function:
Origin:
Soy Isoflavones
Function:
Origin:
Caviar Water
Function:
Origin:

Ratings

All humectants
11.3
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
4.0
4.0
Benchmark
20
Moisturizing rating
6.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 11.3 10
10.0
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 4.0 20
2.0
4.0
Moisturizing rating
6.0
Ingredient Est. % Benchmark Humectancy
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 11.3 10
10
All humectants
11.3
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
All occlusives 4.0 20
2.0
All occlusives
4.0
4.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Acetyl Tetrapeptide-9
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Soy Isoflavones
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 4.3 3 Rich in antioxidants
All antioxidants
4.3
Tocopheryl Acetate
1.5
Mannitol
1.3
Sodium Hyaluronate
0.3
Carnosine
0.3
Laminaria Digitata Extract
0.3
Superoxide Dismutase
0.3
Soy Isoflavones
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.3
0.3
All soothing 1.6 5 No
All soothing
1.6
1.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Dimethicone
Est. %4
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Caprylic Acid
Est. %3
Function
Origin
Caprylic Acid
Sodium Polyacrylate
Est. %2
Function
Origin
Sodium PolyacrylateThis white powder is primarily used as a viscosity controlling agent. It is added to the water phase, which then thickens to form a clear gel. Sodium polyacrylate can also serve as an emollient, absorbent, and emulsion stabilizer.
Tocopheryl Acetate
Est. %1.5
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Mannitol
Est. %1.3
Function
Origin
MannitolA sweet-tasting, sugar-derived, humectant alcohol that can stabilize a skincare formula and offer some antioxidant and soothing properties.
Propylene Glycol
Est. %1
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Cyclopentasiloxane
Est. %0.3
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Fomes Officinalis (Mushroom) Extract
Est. %0.3
Function
Origin
Fomes Officinalis (Mushroom) Extract
Trideceth-6
Est. %0.3
Function
Origin
Trideceth-6
Creatine
Est. %0.3
Function
Origin
CreatineAn amino acid-like compound that regulates cellular energy metabolism. It is used in skincare to moisturize and bind water to the skin and can also improve skin firmness when combined with folic acid.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Laminaria Ochroleuca Extract
Est. %0.3
Function
Origin
Laminaria Ochroleuca ExtractDerived from a species of edible brown seaweed known as golden kelp, this extract contains many different moisturizing and gel-forming polysaccharides, antioxidant compounds, and minerals.
PEG/PPG-18/18 Dimethicone
Est. %0.3
Function
Origin
PEG/PPG-18/18 DimethiconeA silicone-based emulsifier that has the ability to create non-sticky and non-greasy formulas.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Laminaria Saccharina Extract
Est. %0.3
Function
Origin
Laminaria Saccharina ExtractA soothing extract derived from a species of edible brown seaweed called sugar kelp or Devil’s apron (due to its shape and large surface). It contains water-binding and soothing polysaccharides, as well as many beneficial minerals.
Rhamnose
Est. %0.3
Function
Origin
RhamnoseA naturally occurring deoxy sugar that replenishes water levels in the skin.
Carnosine
Est. %0.3
Function
Origin
CarnosineA skin-identical dipeptide that acts as a powerful antioxidant. It protects our skin from harmful glycation and can enhance the activity of other active ingredients in the skincare product.
Disodium Adenosine Triphosphate
Est. %0.3
Function
Origin
Disodium Adenosine Triphosphate
Methylparaben
Est. %0.3
Function
Origin
MethylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Laminaria Digitata Extract
Est. %0.3
Function
Origin
Laminaria Digitata ExtractAn antioxidant extract obtained from an edible brown seaweed called oarweed. It contains many humectant and gelling polysaccharides, as well as beneficial minerals.
Alcohol
Est. %0.3
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
PEG-40 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
PEG-40 Hydrogenated Castor OilA castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
Acetyl Tetrapeptide-9
Est. %0.3
Function
Origin
Acetyl Tetrapeptide-9

A synthetically made peptide that works as a signal peptide, increasing the production of collagen in the skin.

Polysorbate 80
Est. %0.3
Function
Origin
Polysorbate 80A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.
Plankton Extract
Est. %0.3
Function
Origin
Plankton ExtractAn extract from a mixture of various tiny marine animals, algae, seaweeds, and microscopic organisms jointly called plankton. One patent refers to it as a moisturizing humectant ingredient.
Propylparaben
Est. %0.3
Function
Origin
PropylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Pentylene Glycol
Est. %0.3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Superoxide Dismutase
Est. %0.3
Function
Origin
Superoxide Dismutase
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Soy Isoflavones
Est. %0.3
Function
Origin
Soy IsoflavonesBioactive compounds isolated from soybeans. They act as phytoestrogens to support collagen production in aging skin.
Caviar Water
Est. %0.3
Function
Origin
Caviar Water